Polymer supported bases in solution-phase synthesis. 2. A convenient method for N-alkylation reactions of weakly acidic heterocycles

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 9, 1998, Pages 1089-1092

  Xu, Wei ^a   Mohan, Raju ^a   Morrissey, Michael M ^a  

^a BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BASE; HETEROCYCLIC COMPOUND; POLYMER;

ALKYLATION; ARTICLE; CHEMICAL REACTION; METHODOLOGY; SYNTHESIS;

ALKYLATION; CHEMISTRY, ORGANIC; HETEROCYCLIC COMPOUNDS; HETEROCYCLIC COMPOUNDS, 1-RING; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANOPHOSPHORUS COMPOUNDS; POLYMERS;

EID: 0032080369     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00173-5     Document Type: Article

References (18)

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14. 10
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18. 3) δ 1.28 (t, J = 7.2 Hz, 3H), 1.78-1.92 (m, 4H), 2.11 (dt, J= 11.1 and 2.7 Hz, 2H), 2.47 (m, 1H), 2.95 (d, J = 11.1 Hz, 2H), 3.58 (s, 2H), 4.25 (q, J = 7.2 Hz, 2H), 4.90 (s, 2H), 6.39 (s, 1H), 7.34 (d, J = 8.7 Hz, 2H), 7.47 (d, J = 8.4 Hz, 2H), 7.63 (d, J = 8.4 Hz, 2H), 7.69 (d, J = 8.7 Hz, 2H).