-
1
-
-
0029909937
-
Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane:a novel mechanism of regulated trafficking
-
Petris MJ, Mercer JFB, Culvenor, JG, Lockhart P, Gleeson PA, Camakaris J: Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane:a novel mechanism of regulated trafficking. EMBO J 1996, 15:6084-6095. This paper describes the Cu-dependent translocation of the Menkes disease ATPase to the plasma membrane. Cu efflux is a critical component of Cu homeostasis in animal cells.
-
(1996)
EMBO J
, vol.15
, pp. 6084-6095
-
-
Petris, M.J.1
Mercer, J.F.B.2
Culvenor, J.G.3
Lockhart, P.4
Gleeson, P.A.5
Camakaris, J.6
-
2
-
-
0030803730
-
Biochemical characterization cf the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae
-
Hung IH, Suzuki M, Yamaguchi Y, Yuan DS, Klausner RD, Gitlin JD: Biochemical characterization cf the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae. J Biol Chem 1997, 272:21461-21466.
-
(1997)
J Biol Chem
, vol.272
, pp. 21461-21466
-
-
Hung, I.H.1
Suzuki, M.2
Yamaguchi, Y.3
Yuan, D.S.4
Klausner, R.D.5
Gitlin, J.D.6
-
4
-
-
0028916909
-
The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake
-
Yuan DS, Stearman R, Dancis A, Dunn T, Beeler T, Klausner RD: The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake. Proc Natl Acad Sci USA 1995, 92:2632-2636.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2632-2636
-
-
Yuan, D.S.1
Stearman, R.2
Dancis, A.3
Dunn, T.4
Beeler, T.5
Klausner, R.D.6
-
5
-
-
0030898098
-
Identification and functional expression of HAH1, a novel human gene involved in copper homeostasis
-
Klomp LWJ, Lin S-J, Yuan DS, Klausner RD, Culotta VC, Gitlin JD: Identification and functional expression of HAH1, a novel human gene involved in copper homeostasis. J Biol Chem 1997, 272:9221-9226. This paper documents the identification of the human homolog of Atx1, the key Cu chaperone for Fet3 biosynthesis.
-
(1997)
J Biol Chem
, vol.272
, pp. 9221-9226
-
-
Klomp, L.W.J.1
Lin, S.-J.2
Yuan, D.S.3
Klausner, R.D.4
Culotta, V.C.5
Gitlin, J.D.6
-
6
-
-
0031045676
-
Isolation of a cDNa encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment
-
Amaravadi R, Glerum DM, Tzagoloff A: Isolation of a cDNA encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment. Hum Genet 1997, 99:329-333.
-
(1997)
Hum Genet
, vol.99
, pp. 329-333
-
-
Amaravadi, R.1
Glerum, D.M.2
Tzagoloff, A.3
-
7
-
-
0030844529
-
HCTR1: A human gene for copper uptake identified by complementation in yeast
-
Zhou B, Gitschier J: hCTR1: a human gene for copper uptake identified by complementation in yeast Proc Natl Acad Sci USA 1997, 94:7481-7486.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7481-7486
-
-
Zhou, B.1
Gitschier, J.2
-
8
-
-
0030846021
-
Regulation of mitochondrial iron accumulation by Yfh1, a putative homolog of frataxin
-
Babcock M, De Silva D, Oaks R, Davis-Kaplan S, Jiralerspong S, Monteermini L, Pandolfo M, Kaplan, J: Regulation of mitochondrial iron accumulation by Yfh1, a putative homolog of frataxin. Science 1997, 276:1709-1712. Mitochondria are shown to be a key organelle in iron homeostasis. Yfh1 is the susceptibility gene for Friedreich's ataxia and is an important regulator of mitochondria Fe metabolism.
-
(1997)
Science
, vol.276
, pp. 1709-1712
-
-
Babcock, M.1
De Silva, D.2
Oaks, R.3
Davis-Kaplan, S.4
Jiralerspong, S.5
Monteermini, L.6
Pandolfo, M.7
Kaplan, J.8
-
9
-
-
0028152451
-
The Saccharomyces cerevisiae copper transport protein (Ctr1p)
-
Dancis A, Haile D, Yuan DS, Klausner RD: The Saccharomyces cerevisiae copper transport protein (Ctr1p). J Biol Chem 1994, 269:25660-25667.
-
(1994)
J Biol Chem
, vol.269
, pp. 25660-25667
-
-
Dancis, A.1
Haile, D.2
Yuan, D.S.3
Klausner, R.D.4
-
10
-
-
0028961739
-
AFT1: A mediator of iron regulated transcriptional control in Saccharomyces cerevisiae
-
Yamaguchi-Iwai Y, Dancis A, Klausner RD: AFT1: a mediator of iron regulated transcriptional control in Saccharomyces cerevisiae. EMBO J 1995, 14:1231-1239.
-
(1995)
EMBO J
, vol.14
, pp. 1231-1239
-
-
Yamaguchi-Iwai, Y.1
Dancis, A.2
Klausner, R.D.3
-
11
-
-
0029921680
-
A permease-oxidase complex involved in high-affinity iron uptake in yeast
-
Stearman R, Yuan DS, Yamaguchi-Iwai Y, Klausner RD, Dancis A: A permease-oxidase complex involved in high-affinity iron uptake in yeast Science 1996, 271:1552-1557.
-
(1996)
Science
, vol.271
, pp. 1552-1557
-
-
Stearman, R.1
Yuan, D.S.2
Yamaguchi-Iwai, Y.3
Klausner, R.D.4
Dancis, A.5
-
12
-
-
0029911793
-
The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation
-
Zhao H, Eide D: The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proc Natl Acad Sci USA 1996, 93:2354-2458.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2354-2458
-
-
Zhao, H.1
Eide, D.2
-
13
-
-
0030941339
-
Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway
-
Labbe S, Zhu Z, Thiele DJ: Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway. J Biol Chem 1997, 272:15951-15958. This paper identifies the Mac1-responsive DNA element in three Cu-responsive genes in yeast. In vivo footprinting reveals a loss of Mac1 DNA binding in Cu-replete cells.
-
(1997)
J Biol Chem
, vol.272
, pp. 15951-15958
-
-
Labbe, S.1
Zhu, Z.2
Thiele, D.J.3
-
14
-
-
0030757298
-
Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1
-
Yamaguchi-lwai Y, Serpe M, Haile D, Yang W, Kosman DJ, Klausner RD, Dancis A: Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1. J Biol Chem 1997, 272:17711-17718. This paper documents that Mac1 is a specific DNA-binding protein and identifies the DNA binding site in the promoters of Cu-responsive genes.
-
(1997)
J Biol Chem
, vol.272
, pp. 17711-17718
-
-
Yamaguchi-lwai, Y.1
Serpe, M.2
Haile, D.3
Yang, W.4
Kosman, D.J.5
Klausner, R.D.6
Dancis, A.7
-
15
-
-
0026506018
-
Ferric reductase of Saccharomyces cerevisiae: Molecular characterization, role in iron uptake, and transcriptional control by iron
-
Dancis A, Roman DG, Anderson GJ, Hinnebush AG, Klausner RD: Ferric reductase of Saccharomyces cerevisiae: molecular characterization, role in iron uptake, and transcriptional control by iron. Proc Natl Acad Sci USA 1990, 89:3869-3873.
-
(1990)
Proc Natl Acad Sci USA
, vol.89
, pp. 3869-3873
-
-
Dancis, A.1
Roman, D.G.2
Anderson, G.J.3
Hinnebush, A.G.4
Klausner, R.D.5
-
16
-
-
0028205244
-
Two distinctly regulated genes are required for ferric reduction, the first step of iron uptake in Saccharomyces cerevisiae
-
Georgatsou E, Alexandraki D: Two distinctly regulated genes are required for ferric reduction, the first step of iron uptake in Saccharomyces cerevisiae. Mol Cell Biol 1994, 14:3065-3073.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3065-3073
-
-
Georgatsou, E.1
Alexandraki, D.2
-
17
-
-
0028799741
-
Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae
-
Hassett R, Kosman DJ: Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae. J Biol Chem 1995, 270:128-134.
-
(1995)
J Biol Chem
, vol.270
, pp. 128-134
-
-
Hassett, R.1
Kosman, D.J.2
-
18
-
-
0029946913
-
Evidence for the Saccharomyces cerevisiae ferrireductase system being a multicomponent electron transfer chain
-
Lesuisse E, Casteras-Simon M, Labbe P: Evidence for the Saccharomyces cerevisiae ferrireductase system being a multicomponent electron transfer chain. J Biol Chem 1996, 271:13578-13583.
-
(1996)
J Biol Chem
, vol.271
, pp. 13578-13583
-
-
Lesuisse, E.1
Casteras-Simon, M.2
Labbe, P.3
-
19
-
-
15844366125
-
The FRE1 ferric reductase of Saccharomyces cerevisiae is a cytochromeb similar to that of NADPH oxidase
-
Shatwell KP, Dancis A, Cross AR, Klausner RD, Segal AW: The FRE1 ferric reductase of Saccharomyces cerevisiae is a cytochromeb similar to that of NADPH oxidase. J Biol Chem 1996, 271:14240-14244. This paper shows that the cell surface metalloreductase Frei is a b-type cytochrome similar to that found in the human neutrophils suggesting that metalloreduction by Fre1, and probably by Fre2, is achieved through reduced nicotinamide dinucletide phosphate (NADPH) oxidation.
-
(1996)
J Biol Chem
, vol.271
, pp. 14240-14244
-
-
Shatwell, Kp.1
Dancis, A.2
Cross, A.R.3
Klausner, R.D.4
Segal, A.W.5
-
20
-
-
0030924805
-
The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator
-
Georgatsou E, Mavrogiananis LA, Fragiadakis GS, Alexandraki D: The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator. J Biol Chem 1997, 272:13786-13792.
-
(1997)
J Biol Chem
, vol.272
, pp. 13786-13792
-
-
Georgatsou, E.1
Mavrogiananis, L.A.2
Fragiadakis, G.S.3
Alexandraki, D.4
-
21
-
-
0030054971
-
Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast
-
Yamaguchi-iwai Y, Stearman R, Dancis A, Klausner RD: Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast. EMBO J 1996, 15:3377-3384. Aft1 is shown to regulate expression of a series of genes whose products are involved in Fe uptake. Included in the regulon are the Atx1 Cu chaperone and Ccc2 Menkes-like ATPase both of which are important for biosynthesis of Fet3.
-
(1996)
EMBO J
, vol.15
, pp. 3377-3384
-
-
Yamaguchi-iwai, Y.1
Stearman, R.2
Dancis, A.3
Klausner, R.D.4
-
22
-
-
0028893379
-
The FET3 gene product required for high affinity iron transport in yeast is a cell surface ferroxidase
-
De Silva DM, Askwith CC, Eide D, Kaplan J: The FET3 gene product required for high affinity iron transport in yeast is a cell surface ferroxidase. J Biol Chem 1995, 270:1098-1101.
-
(1995)
J Biol Chem
, vol.270
, pp. 1098-1101
-
-
De Silva, D.M.1
Askwith, C.C.2
Eide, D.3
Kaplan, J.4
-
23
-
-
0030945592
-
Purification and characterization of Fet3 protein, a yeast homologue of ceruloplasmin
-
DeSilva D, Davis-Kaplan S, Fergestad J, Kaplan J: Purification and characterization of Fet3 protein, a yeast homologue of ceruloplasmin. J Biol Chem 1997, 272:14208-14213.
-
(1997)
J Biol Chem
, vol.272
, pp. 14208-14213
-
-
Desilva, D.1
Davis-Kaplan, S.2
Fergestad, J.3
Kaplan, J.4
-
24
-
-
0029841951
-
The ZRT2 gene encodes the low affinity zinc transporter in Saccharomyces cerevisiae
-
Zhao H, Eide D: The ZRT2 gene encodes the low affinity zinc transporter in Saccharomyces cerevisiae. J Biol Chem 1996, 38:23203-23210.
-
(1996)
J Biol Chem
, vol.38
, pp. 23203-23210
-
-
Zhao, H.1
Eide, D.2
-
25
-
-
0029911793
-
The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation
-
Zhao H, Eide D: The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proc Natl Acad Sci USA 1996, 93:2454-2458.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2454-2458
-
-
Zhao, H.1
Eide, D.2
-
26
-
-
0027500845
-
MAC1, a nuclear regulatory protein related to Cu dependent transcription factors is involved in Cu/Fe utiltization and stress resistance in yeast
-
Jungmann J, Reins HA, Lee J, Romeo A, Hassett R, Kosman D, Jentsch S: MAC1, a nuclear regulatory protein related to Cu dependent transcription factors is involved in Cu/Fe utiltization and stress resistance in yeast EMBO J 1993, 12:5061-5056.
-
(1993)
EMBO J
, vol.12
, pp. 5061-15056
-
-
Jungmann, J.1
Reins, H.A.2
Lee, J.3
Romeo, A.4
Hassett, R.5
Kosman, D.6
Jentsch, S.7
-
27
-
-
0030967609
-
Copper-mediated repression of the activation domain in the yeast Mac1p transcription factor
-
Graden JA, Winge DR: Copper-mediated repression of the activation domain in the yeast Mac1p transcription factor. Proc Natl Acad Sci USA 1997, 94:5550-5555. This paper documents that Mac1 contains a Cu-regulated transactivation domain. Metal-ion regulation of transactivation function has not been previously observed.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5550-5555
-
-
Graden, J.A.1
Winge, D.R.2
-
28
-
-
0030891788
-
Sensors that mediate copper-specific activation and repression of gene expression
-
Winge DR, Graden JA, Posewitz MC, Martins LJ, Jensen LT, Simon JR: Sensors that mediate copper-specific activation and repression of gene expression. J Bioinorg Chem 1997, 2:2-10. A general review of copper-ion regulation of gene expression in yeast focusing on both Cu activation and Cu inhibition of expression.
-
(1997)
J Bioinorg Chem
, vol.2
, pp. 2-10
-
-
Winge, D.R.1
Graden, J.A.2
Posewitz, M.C.3
Martins, L.J.4
Jensen, L.T.5
Simon, J.R.6
-
29
-
-
0030920037
-
The AFT1 transcription factor is differentially required for expression of high-affinity iron uptake genes in Saccharomyces cerevisiae
-
Casas C, Aldea M, Espinet C, Gallego C, Gil R, Herero E: The AFT1 transcription factor is differentially required for expression of high-affinity iron uptake genes in Saccharomyces cerevisiae. Yeast 1997, 13:621-637.
-
(1997)
Yeast
, vol.13
, pp. 621-637
-
-
Casas, C.1
Aldea, M.2
Espinet, C.3
Gallego, C.4
Gil, R.5
Herero, E.6
-
30
-
-
0030794279
-
Zap1p, a metalloregulatory protein involved in zinc-responsive transcriptional regulation in Saccharomyces cerevisiae
-
Zhao H, Eide DJ: Zap1p, a metalloregulatory protein involved in zinc-responsive transcriptional regulation in Saccharomyces cerevisiae. Mol Cell Biol 1997, 17:5044-5052. The identification of the key regulator of Zn(II) plasma membrane transporters is the focus of this important paper. Zap1 appears to a Zn-responsive transcription factor.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5044-5052
-
-
Zhao, H.1
Eide, D.J.2
-
31
-
-
0024291353
-
Copper activates metallothionein gene transcription by altering the conformation of a specific DNa binding protein
-
Furst P, Hu S, Hackett R, Hamer D: Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein. Cell 1988, 55:705-717.
-
(1988)
Cell
, vol.55
, pp. 705-717
-
-
Furst, P.1
Hu, S.2
Hackett, R.3
Hamer, D.4
-
32
-
-
0026743186
-
Expression of a yeast metallothionein gene family is activated by a single metalloregulatory transcription factor
-
Zhou P, Szczypka MS, Sosinowski T, Thiele DJ: Expression of a yeast metallothionein gene family is activated by a single metalloregulatory transcription factor. Mol Cell Biol 1992, 12:3766-3775.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3766-3775
-
-
Zhou, P.1
Szczypka, M.S.2
Sosinowski, T.3
Thiele, D.J.4
-
33
-
-
0030446028
-
Presence of a copper(I)-thiolate regulatory domain in the copper-activated transcription factor Amt1
-
Graden JA, Posewitz MC, Simon JR, George GN, Pickering IJ, Winge DR: Presence of a copper(I)-thiolate regulatory domain in the copper-activated transcription factor Amt1. Biochemistry 1996, 35:14583-14589. Mapping studies on Amt1 reveal that Cu-modulation of DNA-binding activity occurs by reversible formation of a Cu-thiolate cluster within a regulatory domain.
-
(1996)
Biochemistry
, vol.35
, pp. 14583-14589
-
-
Graden, J.A.1
Posewitz, M.C.2
Simon, J.R.3
George, G.N.4
Pickering, I.J.5
Winge, D.R.6
-
34
-
-
0030050312
-
Identification of the Zn(II) site in the copper-responsive yeast transcription factor, AMT1: A conserved Zn module
-
Farrell RA, Thorvaldsen JL, Winge DR: Identification of the Zn(II) site in the copper-responsive yeast transcription factor, AMT1: a conserved Zn module. Biochemistry 1996, 35:1571-1580.
-
(1996)
Biochemistry
, vol.35
, pp. 1571-1580
-
-
Farrell, R.A.1
Thorvaldsen, J.L.2
Winge, D.R.3
-
35
-
-
0027257306
-
Rapid transcriptional autoregulation of a yeast metalloregulatory transcription factor is essential for high-level copper detoxification
-
Zhou P, Thiele DJ: Rapid transcriptional autoregulation of a yeast metalloregulatory transcription factor is essential for high-level copper detoxification. Genes Dev 1993, 7:1824-1835.
-
(1993)
Genes Dev
, vol.7
, pp. 1824-1835
-
-
Zhou, P.1
Thiele, D.J.2
-
36
-
-
0030067833
-
Autoactivation by a Candida glabrata copper metalloregulatory transcription factor requires critical minor groove interactions
-
Koch KA, Thiele DJ: Autoactivation by a Candida glabrata copper metalloregulatory transcription factor requires critical minor groove interactions. Mol Cell Biol 1996, 16:724-734.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 724-734
-
-
Koch, K.A.1
Thiele, D.J.2
-
37
-
-
0029039920
-
The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity
-
Lin S, Culotta VC: The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity. Proc Natl Acad Sci USA 1995, 92:3784-3788.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3784-3788
-
-
Lin, S.1
Culotta, V.C.2
-
38
-
-
0030820818
-
Restriction of copper export in Saccharomyces cerevisiae to a late Golgi or post-Golgi compartment in the secretory pathway
-
Yuan DS, Dancis A, Klausner RD: Restriction of copper export in Saccharomyces cerevisiae to a late Golgi or post-Golgi compartment in the secretory pathway. J Biol Chem 1997, 272:25787-25793.
-
(1997)
J Biol Chem
, vol.272
, pp. 25787-25793
-
-
Yuan, D.S.1
Dancis, A.2
Klausner, R.D.3
-
39
-
-
0030910597
-
A role for the Saccharomyces cerevisiae ATX1 gene is copper trafficking and iron transport
-
Lin S-J, Pufahl RA, Dancis A, O'Halloran TVO, Culotta VC: A role for the Saccharomyces cerevisiae ATX1 gene is copper trafficking and iron transport. J Biol Chem 1997, 272:9215-9220. This papers documents one important role of Atx1 in being a Cu chaperone for delivery of Cu(I) ions to the Ccc2 ATPase transporter for assembly of Fet3.
-
(1997)
J Biol Chem
, vol.272
, pp. 9215-9220
-
-
Lin, S.-J.1
Pufahl, R.A.2
Dancis, A.3
O'Halloran, T.V.O.4
Culotta, V.C.5
-
40
-
-
0031005931
-
Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast
-
Radisky DC, Snyder WB, Emr SD, Kaplan J: Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast Proc Natl Acad Sci USA 1997, 94:5662-5666.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5662-5666
-
-
Radisky, D.C.1
Snyder, W.B.2
Emr, S.D.3
Kaplan, J.4
-
41
-
-
1842366025
-
Metal ion chaperone function of the soluble Cu(I) receptor Atx1
-
Pufahl RA, Singer CP, Peariso KL, Lin S-J, Schmidt P, Fahrni C, Culotta VC, Penner-Hahn JE, O'Halloran TVO: Metal ion chaperone function of the soluble Cu(I) receptor Atx1. Science 1997, 277:853-856. This paper is the first characterization of Atx1 as a Cu-binding protein and shows that Atx1 interacts with the the amino-terminal segment of Ccc2 transporter. The amino-terminal segment of Ccc2 contains conserved Cu-binding modules.
-
(1997)
Science
, vol.277
, pp. 853-856
-
-
Pufahl, R.A.1
Singer, C.P.2
Peariso, K.L.3
Lin, S.-J.4
Schmidt, P.5
Fahrni, C.6
Culotta, V.C.7
Penner-Hahn, J.E.8
O'Halloran, T.V.O.9
-
42
-
-
15844421373
-
Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase
-
Glerum DM, Shtanko A, Tzagoloff A: Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase. J Biol Chem 1996, 271:14504-14509. The identification of Cox17 as an important factor for assembly of cytochrome oxidase is the focus of this paper. The data are consistent with Cox1 7 being a Cu chaperone for delivery of Cu ions to the cytochrome oxidase complex preassembled in the inner mitochondrial membrane.
-
(1996)
J Biol Chem
, vol.271
, pp. 14504-14509
-
-
Glerum, D.M.1
Shtanko, A.2
Tzagoloff, A.3
-
43
-
-
0030802648
-
The copper chaperone for superoxide dismutase
-
Culotta VC, Klomp LWJ, Strain J, Casareno RLB, Krems B, Gitlin JD: The copper chaperone for superoxide dismutase. J Biol Chem 1997, 272:23469-23472. An important paper showing that formation of active superoxide dismutase requires the function of the soluble Lys7 protein. Lys7 contains a candidate Cu-binding motif found in Atx1 and Cu-ATPase transporters.
-
(1997)
J Biol Chem
, vol.272
, pp. 23469-23472
-
-
Culotta, V.C.1
Klomp, L.W.J.2
Strain, J.3
Casareno, R.L.B.4
Krems, B.5
Gitlin, J.D.6
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