메뉴 건너뛰기




Volumn 51, Issue 1, 1998, Pages 30-34

Correlation of cyclin D 1 and Rb gene expression with apoptosis in invasive breast cancer

Author keywords

Apoptosis; Breast cancer; Cyclin D1; Histological grade; Histological type; Immunohistochemistry; Retinoblastoma susceptibility gene

Indexed keywords

CYCLIN D1; RETINOBLASTOMA PROTEIN; TUMOR PROTEIN;

EID: 0031995120     PISSN: 13668714     EISSN: None     Source Type: Journal    
DOI: 10.1136/mp.51.1.30     Document Type: Article
Times cited : (13)

References (56)
  • 1
    • 0028559479 scopus 로고
    • Apoptosis in breast cancer as related to histopathological characteristics and prognosis
    • Lipponen P, Aaltomaa S, Kosma VM, et al. Apoptosis in breast cancer as related to histopathological characteristics and prognosis. Eur J Cancer 1994;30A:2068-73.
    • (1994) Eur J Cancer , vol.30 A , pp. 2068-2073
    • Lipponen, P.1    Aaltomaa, S.2    Kosma, V.M.3
  • 2
    • 0028301094 scopus 로고
    • p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation
    • Clarke AR, Gledhill S, Hooper ML, et al. p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation. Oncogen 1994;9:1767-73.
    • (1994) Oncogen , vol.9 , pp. 1767-1773
    • Clarke, A.R.1    Gledhill, S.2    Hooper, M.L.3
  • 3
    • 0028335717 scopus 로고
    • Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
    • Miyashita T, Krajewski S, Krajewska M, et al. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Ocogene 1994;9:1799-805.
    • (1994) Ocogene , vol.9 , pp. 1799-1805
    • Miyashita, T.1    Krajewski, S.2    Krajewska, M.3
  • 4
    • 0028072523 scopus 로고
    • DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2
    • Strasser A, Harris AW, Jacks T, et al. DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell 1994;79:329-39.
    • (1994) Cell , vol.79 , pp. 329-339
    • Strasser, A.1    Harris, A.W.2    Jacks, T.3
  • 5
    • 0028944271 scopus 로고
    • Expression of the bcl-2 gene family in normal and malignant breast tissue: Low bax-alpha expression in tumor cells correlates with resistance towards apoptosis
    • Bargou RC, Daniel PT, Mapara MY, et al. Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis. Int J Cancer 1995;60:854-9.
    • (1995) Int J Cancer , vol.60 , pp. 854-859
    • Bargou, R.C.1    Daniel, P.T.2    Mapara, M.Y.3
  • 6
    • 0029032660 scopus 로고
    • Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax
    • Hanada M, Aime-Sempe C, Sato T, et al. Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax. J Biol Chem 1995; 270:11962-9.
    • (1995) J Biol Chem , vol.270 , pp. 11962-11969
    • Hanada, M.1    Aime-Sempe, C.2    Sato, T.3
  • 7
    • 0027130238 scopus 로고
    • Bcl-2 Bax: A rheostat that regulates an anti-oxidant pathway and cell death
    • Korsmeyer SJ, Shutter JR, Veis DJ, et al. Bcl-2 Bax: a rheostat that regulates an anti-oxidant pathway and cell death. Sem Cancer Biol 1993;4:327-32.
    • (1993) Sem Cancer Biol , vol.4 , pp. 327-332
    • Korsmeyer, S.J.1    Shutter, J.R.2    Veis, D.J.3
  • 8
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltavi ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993;74:609-12.
    • (1993) Cell , vol.74 , pp. 609-612
    • Oltavi, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 9
    • 0028986876 scopus 로고
    • Induction of apoptosis by the Bcl-2 homologue Bak
    • Chittenden T, Harrington EA, O'Connor R, et al. Induction of apoptosis by the Bcl-2 homologue Bak. Nature 1995;374:733-6.
    • (1995) Nature , vol.374 , pp. 733-736
    • Chittenden, T.1    Harrington, E.A.2    O'Connor, R.3
  • 10
    • 0028946015 scopus 로고
    • Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K
    • Farrow SN, White JH, Martinou I, et al. Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature 1995;374:731-3.
    • (1995) Nature , vol.374 , pp. 731-733
    • Farrow, S.N.1    White, J.H.2    Martinou, I.3
  • 11
    • 0028904163 scopus 로고
    • Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak
    • Kiefer MC, Brauer MJ, Powers VC, et al. Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature 1995;374:736-9.
    • (1995) Nature , vol.374 , pp. 736-739
    • Kiefer, M.C.1    Brauer, M.J.2    Powers, V.C.3
  • 12
    • 0027282044 scopus 로고
    • Bcl-x, a Bcl-2 related gene that functions as a dominant regulator of apoptotic cell death
    • Boise LH, Gonzalez-Garcia M, Postema CE, et al. Bcl-x, a Bcl-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993;74:597-608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3
  • 13
    • 0027485461 scopus 로고
    • Bcl-2 functions in a antioxidant pathway to prevent apoptosis
    • Hockenberry DM, Oltavi ZN, Yin XM, et al. Bcl-2 functions in a antioxidant pathway to prevent apoptosis. Cell 1993;75:241-51.
    • (1993) Cell , vol.75 , pp. 241-251
    • Hockenberry, D.M.1    Oltavi, Z.N.2    Yin, X.M.3
  • 14
    • 0023786047 scopus 로고
    • Bcl-2 promotes the survival of haemopoietic cells and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, Adams TM. Bcl-2 promotes the survival of haemopoietic cells and cooperates with c-myc to immortalize pre-B cells, Nature 1988;335:440-2.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, T.M.3
  • 15
    • 0027513663 scopus 로고
    • Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2
    • Wagner AJ, Small MB, Hay N. Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2. Mol Cell Biol 1993; 13:2432-40.
    • (1993) Mol Cell Biol , vol.13 , pp. 2432-2440
    • Wagner, A.J.1    Small, M.B.2    Hay, N.3
  • 16
    • 0026688162 scopus 로고
    • Apoptotic cell death induced by c-myc is inhibited by bcl-2
    • Bisonette RP, Echeverri F, Mahboubi A, et al. Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature 1992; 359:552-4.
    • (1992) Nature , vol.359 , pp. 552-554
    • Bisonette, R.P.1    Echeverri, F.2    Mahboubi, A.3
  • 17
    • 0028915222 scopus 로고
    • Molecular foundations of cancer. New targets for intervention
    • Karp JE, Broder S. Molecular foundations of cancer. New targets for intervention. Nat Med 1995;1:309-20.
    • (1995) Nat Med , vol.1 , pp. 309-320
    • Karp, J.E.1    Broder, S.2
  • 18
    • 0027958344 scopus 로고
    • Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines
    • Lukas J, Pagano M, Staskova Z, et al. Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines. Oncogene 1994;9:707-18.
    • (1994) Oncogene , vol.9 , pp. 707-718
    • Lukas, J.1    Pagano, M.2    Staskova, Z.3
  • 19
    • 0028953560 scopus 로고
    • Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck
    • Michalides R, Veelen N van, Hart A, et al. Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck. Cancer Res 1995;55:975-8.
    • (1995) Cancer Res , vol.55 , pp. 975-978
    • Michalides, R.1    Van Veelen, N.2    Hart, A.3
  • 20
    • 0029883680 scopus 로고    scopus 로고
    • A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer
    • Michalides R, Hageman PH, Tinteren H van, et al. A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer. Br J Cancer 1996;73:728-34.
    • (1996) Br J Cancer , vol.73 , pp. 728-734
    • Michalides, R.1    Hageman, P.H.2    Van Tinteren, H.3
  • 22
    • 0026521388 scopus 로고
    • Identification and cloning of two overexpressed genes, U21B31 PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas
    • Schuuring E, Verhoeven E, Mooi WJ, et al. Identification and cloning of two overexpressed genes, U21B31 PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas. Oncogene 1992;7:355-61.
    • (1992) Oncogene , vol.7 , pp. 355-361
    • Schuuring, E.1    Verhoeven, E.2    Mooi, W.J.3
  • 23
    • 0026744608 scopus 로고
    • Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer
    • Schuuring E, Verhoeven E, Tinteren H van, et al. Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer. Cancer Res 1992;52:5229-34.
    • (1992) Cancer Res , vol.52 , pp. 5229-5234
    • Schuuring, E.1    Verhoeven, E.2    Van Tinteren, H.3
  • 24
    • 0025970229 scopus 로고
    • D112287, a putative oncogene on chromosome 11q13 is amplified and expressed in squamous cell and mammary carcinomas and linked to bcl-1
    • Lammie G, Fantl V, Smith R, et al. D112287, a putative oncogene on chromosome 11q13 is amplified and expressed in squamous cell and mammary carcinomas and linked to bcl-1. Oncogene 1991;6:439-44.
    • (1991) Oncogene , vol.6 , pp. 439-444
    • Lammie, G.1    Fantl, V.2    Smith, R.3
  • 25
    • 0031031998 scopus 로고    scopus 로고
    • Cyclin D1 expression in invasive breast cancer: Correlations and prognostic value
    • Diest PJ van, Michalides RJAM, Jannink I, et al. Cyclin D1 expression in invasive breast cancer: correlations and prognostic value. Am J Pathol 1997;150:705-11.
    • (1997) Am J Pathol , vol.150 , pp. 705-711
    • Van Diest, P.J.1    Michalides, R.J.A.M.2    Jannink, I.3
  • 26
    • 0029893319 scopus 로고    scopus 로고
    • Cyclin D1 and prognosis in human breast cancer
    • Gillett C, Smith P, Gregory W, et al. Cyclin D1 and prognosis in human breast cancer. Int J Cancer 1996;69:92-9.
    • (1996) Int J Cancer , vol.69 , pp. 92-99
    • Gillett, C.1    Smith, P.2    Gregory, W.3
  • 27
    • 0029111421 scopus 로고
    • Determination of the prognostic value of cyclin D1 overexpression in breast cancer
    • McIntosh GG, Anderson JJ, Milton I, et al. Determination of the prognostic value of cyclin D1 overexpression in breast cancer. Oncogene 1995;11:885-91.
    • (1995) Oncogene , vol.11 , pp. 885-891
    • McIntosh, G.G.1    Anderson, J.J.2    Milton, I.3
  • 28
    • 0030041916 scopus 로고    scopus 로고
    • Cyclin D1 amplification and expression in human breast carcinoma: Correlation with histological prognostic markers and oestrogen receptor expression
    • Worsley SD, Jennings BA, Khalil KH, et al. Cyclin D1 amplification and expression in human breast carcinoma: correlation with histological prognostic markers and oestrogen receptor expression. J Clin Pathol: Mol Pathol 1996;49:M46-50.
    • (1996) J Clin Pathol: Mol Pathol , vol.49
    • Worsley, S.D.1    Jennings, B.A.2    Khalil, K.H.3
  • 29
    • 0029025644 scopus 로고
    • Cyclin D1 (PRAD1) protein expression in breast cancer: Approximately one-third of infiltrating mammary carcinomas show overexpression of the cyclin D1 oncogene
    • Zukerberg LR, Yang WI, Gadd M, et al. Cyclin D1 (PRAD1) protein expression in breast cancer: approximately one-third of infiltrating mammary carcinomas show overexpression of the cyclin D1 oncogene. Mod Pathol 1995;8:560-7.
    • (1995) Mod Pathol , vol.8 , pp. 560-567
    • Zukerberg, L.R.1    Yang, W.I.2    Gadd, M.3
  • 30
    • 0026064404 scopus 로고
    • Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumours
    • Rosenberg CL, Kim HG, Shows TB, et al. Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumours. Oncogene 1991;6:449-53.
    • (1991) Oncogene , vol.6 , pp. 449-453
    • Rosenberg, C.L.1    Kim, H.G.2    Shows, T.B.3
  • 31
    • 0025806904 scopus 로고
    • A novel cyclin encoded by a bcll-linked candidate oncogene
    • Motokura T, Bloom T, Kim HG, et al. A novel cyclin encoded by a bcll-linked candidate oncogene. Nature 1991;350:512-15.
    • (1991) Nature , vol.350 , pp. 512-515
    • Motokura, T.1    Bloom, T.2    Kim, H.G.3
  • 32
    • 0028324310 scopus 로고
    • Analysis of cell cyclerelated gene expression in postmitotic neurons: Selective induction of cyclin D1 during programmed cell death
    • Freeman RS, Estus S, Johnson EM Jr. Analysis of cell cyclerelated gene expression in postmitotic neurons: selective induction of cyclin D1 during programmed cell death. Neuron 1994;12:343-55.
    • (1994) Neuron , vol.12 , pp. 343-355
    • Freeman, R.S.1    Estus, S.2    Johnson Jr., E.M.3
  • 33
    • 0030031514 scopus 로고    scopus 로고
    • Cyclin D1 is an essential mediator of apoptotic neuronal cell death
    • Kranenburg O, van der Eb AJ, Zantema A. Cyclin D1 is an essential mediator of apoptotic neuronal cell death. EMBO J 1996;15:46-54.
    • (1996) EMBO J , vol.15 , pp. 46-54
    • Kranenburg, O.1    Van Der Eb, A.J.2    Zantema, A.3
  • 34
    • 0028861428 scopus 로고
    • Inhibition of apoptosis by the retinoblastoma gene product
    • Haas-Kogan DA, Kogan SC, Levi D, et al. Inhibition of apoptosis by the retinoblastoma gene product. EMBO J 1995;14:461-72.
    • (1995) EMBO J , vol.14 , pp. 461-472
    • Haas-Kogan, D.A.1    Kogan, S.C.2    Levi, D.3
  • 35
    • 0029883399 scopus 로고    scopus 로고
    • The retinoblastoma gene product inhibits TGF-betal induced apoptosis in primary rat hepatocytes and human HuH-7 hepatoma cells
    • Fan G, Ma X, Kren BT, et al. The retinoblastoma gene product inhibits TGF-betal induced apoptosis in primary rat hepatocytes and human HuH-7 hepatoma cells. Oncogene 1996;12:1909-19.
    • (1996) Oncogene , vol.12 , pp. 1909-1919
    • Fan, G.1    Ma, X.2    Kren, B.T.3
  • 36
    • 0029915968 scopus 로고    scopus 로고
    • Retinoblastoma protein inhibits IFN-gamma induced apoptosis
    • Berry DH, Lu Y, Schmidt B, et al. Retinoblastoma protein inhibits IFN-gamma induced apoptosis. Oncogene 1996;12: 1809-19.
    • (1996) Oncogene , vol.12 , pp. 1809-1819
    • Berry, D.H.1    Lu, Y.2    Schmidt, B.3
  • 37
    • 0028999429 scopus 로고
    • p53-mediated apoptosis in HeLa cells can be overcome by excess pRb
    • Haupt Y, Rowan S, Oren M. p53-mediated apoptosis in HeLa cells can be overcome by excess pRb. Oncongene 1995; 10:1563-71.
    • (1995) Oncongene , vol.10 , pp. 1563-1571
    • Haupt, Y.1    Rowan, S.2    Oren, M.3
  • 38
    • 0001271962 scopus 로고
    • Grading of invasive carcinoma of the breast
    • Page DL, Anderson TJ, eds. Edinburgh: Churchill Livingstone
    • Elston CW. Grading of invasive carcinoma of the breast. In: Page DL, Anderson TJ, eds. Diagnostic histopathology of the breast Edinburgh: Churchill Livingstone, 1987:300-11.
    • (1987) Diagnostic Histopathology of the Breast , pp. 300-311
    • Elston, C.W.1
  • 39
    • 0028308702 scopus 로고
    • Cyclin D1 protein expression and function in human breast cancer
    • Bartkova J, Lukas J, Müller H, et al. Cyclin D1 protein expression and function in human breast cancer. Int J Cancer 1994;57:353-61.
    • (1994) Int J Cancer , vol.57 , pp. 353-361
    • Bartkova, J.1    Lukas, J.2    Müller, H.3
  • 40
    • 0029783518 scopus 로고    scopus 로고
    • Counting of apoptotic cells: A methodological study in invasive breast cancer
    • Schepop HAM, Jong JS de, Diest PJ van, et al. Counting of apoptotic cells: a methodological study in invasive breast cancer. J Clin Pathol: Mol Pathol 1996;49:M214-17.
    • (1996) J Clin Pathol: Mol Pathol , vol.49
    • Schepop, H.A.M.1    De Jong, J.S.2    Van Diest, P.J.3
  • 41
    • 0027434345 scopus 로고
    • A new method to detect apoptosis in paraffin sections: In situ end-labeling of fragmented DNA
    • Weisman JH, Jonker RR, Keijzer R, et al. A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA. J Histochem Cytochem 1993;41:7-12.
    • (1993) J Histochem Cytochem , vol.41 , pp. 7-12
    • Weisman, J.H.1    Jonker, R.R.2    Keijzer, R.3
  • 42
    • 0028135177 scopus 로고
    • Immunohistochemistry of cyclin D1 in human breast cancer
    • Zhang SY, Caamano J, Cooper F, et al. Immunohistochemistry of cyclin D1 in human breast cancer. Am J Clin Pathol 1994;102:695-8.
    • (1994) Am J Clin Pathol , vol.102 , pp. 695-698
    • Zhang, S.Y.1    Caamano, J.2    Cooper, F.3
  • 43
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
    • Gillet C, Fantl V, Smith R, et al. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 1994;54:1812-17.
    • (1994) Cancer Res , vol.54 , pp. 1812-1817
    • Gillet, C.1    Fantl, V.2    Smith, R.3
  • 46
    • 0028907553 scopus 로고
    • Stable overexpression of cyclin D1 in a human mammary epithelial cell line prolongs the S-phase and inhibits growth
    • Han EK-H, Sgambato A, Jiang W, et al. Stable overexpression of cyclin D1 in a human mammary epithelial cell line prolongs the S-phase and inhibits growth. Oncogene 1995;10:953-61.
    • (1995) Oncogene , vol.10 , pp. 953-961
    • Han, E.K.-H.1    Sgambato, A.2    Jiang, W.3
  • 47
    • 0028129498 scopus 로고
    • Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts
    • Pagano M, Theodoras AM, Tam SW, et al. Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes Dev 1994;8:1627-39.
    • (1994) Genes Dev , vol.8 , pp. 1627-1639
    • Pagano, M.1    Theodoras, A.M.2    Tam, S.W.3
  • 48
    • 0027078657 scopus 로고
    • Retinoblastoma and p53 gene product expression in breast carcinoma: Immunohistochemical analysis and clinicopathologic correlation
    • Trudel M, Mulligan L, Cavenee W, et al. Retinoblastoma and p53 gene product expression in breast carcinoma: immunohistochemical analysis and clinicopathologic correlation. Hum Pathol 1992;23:1388-94.
    • (1992) Hum Pathol , vol.23 , pp. 1388-1394
    • Trudel, M.1    Mulligan, L.2    Cavenee, W.3
  • 49
    • 0028951667 scopus 로고
    • Expression of retinoblastoma gene protein (Rb) in breast cancer as related to established prognostic factors and survival
    • Pietilainen T, Lipponen P, Aaltomaa S, et al. Expression of retinoblastoma gene protein (Rb) in breast cancer as related to established prognostic factors and survival, Eur J Cancer 1995;31A:329-33.
    • (1995) Eur J Cancer , vol.31 A , pp. 329-333
    • Pietilainen, T.1    Lipponen, P.2    Aaltomaa, S.3
  • 50
    • 0026729463 scopus 로고
    • The retinoblasoma gene in breast cancer: Allele loss is not correlated with loss of gene protein expression
    • Borg Á, Zhang QX, Alm P, et al. The retinoblasoma gene in breast cancer: allele loss is not correlated with loss of gene protein expression. Cancer Res 1992;52:2991-4.
    • (1992) Cancer Res , vol.52 , pp. 2991-2994
    • Borg, Á.1    Zhang, Q.X.2    Alm, P.3
  • 51
    • 0027264009 scopus 로고
    • TGF alpha and TGF beta expression in mammary carcinoma
    • Dublin EA, Barnes DM, Wang DY, et al. TGF alpha and TGF beta expression in mammary carcinoma. J Pathol 1993;179:15-22.
    • (1993) J Pathol , vol.179 , pp. 15-22
    • Dublin, E.A.1    Barnes, D.M.2    Wang, D.Y.3
  • 52
    • 0025010999 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of growth factors, TGF-alpha, TGF-beta, IGF-I, and neu oncogene product in benign and malignant human breast tissues
    • Mizukami Y, Nonomura A, Yamada T, et al. Immunohistochemical demonstration of growth factors, TGF-alpha, TGF-beta, IGF-I, and neu oncogene product in benign and malignant human breast tissues. Anticancer Res 1996;10:1115-26.
    • (1996) Anticancer Res , vol.10 , pp. 1115-1126
    • Mizukami, Y.1    Nonomura, A.2    Yamada, T.3
  • 54
    • 0028171968 scopus 로고
    • Mediation of c-myc induced apoptosis by p53
    • Hermeking H, Eick D. Mediation of c-myc induced apoptosis by p53. Science 1994;265:2091-3.
    • (1994) Science , vol.265 , pp. 2091-2093
    • Hermeking, H.1    Eick, D.2
  • 55
    • 0027944957 scopus 로고
    • Bcl-2 protein expression and long-term survival in breast cancer
    • Joensuu H, Pylkkanan L, Toikkanan S. Bcl-2 protein expression and long-term survival in breast cancer. Am J Pathol 1994;145:1191-8.
    • (1994) Am J Pathol , vol.145 , pp. 1191-1198
    • Joensuu, H.1    Pylkkanan, L.2    Toikkanan, S.3
  • 56
    • 0028609620 scopus 로고
    • Mcl-1, a member of the Bcl-2 family, delays apoptosis induced by c-myc overexpression in chinese hamster ovary cells
    • Reynolds JE, Yang T, Qian L, et al, Mcl-1, a member of the Bcl-2 family, delays apoptosis induced by c-myc overexpression in chinese hamster ovary cells. Cancer Res 1994;54:6348-52.
    • (1994) Cancer Res , vol.54 , pp. 6348-6352
    • Reynolds, J.E.1    Yang, T.2    Qian, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.