Pharmacological characterization of apoptotic cell death in a model of photothrombotic brain injury in rats

Brain Research

Volumn 734, Issue 1-2, 1996, Pages 1-9

  Kharlamov, Alexander ^a   Uz, Tolga ^b   Joo, Jin Yang ^a   Manev, Hari ^b  

^a ALLEGHENY SINGER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Apoptosis; Cycloheximide; Excitotoxicity; Glutamate; Programmed cell death; Propidium iodide; Stroke

Indexed keywords

AURINTRICARBOXYLIC ACID; CYCLOHEXIMIDE; DIZOCILPINE; DNA FRAGMENT; GLUTAMATE RECEPTOR ANTAGONIST; ROSE BENGAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR CORTEX; STROKE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030599159     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00274-0     Document Type: Article

References (37)

1. [1] Alexianu, M.E., Mohamed, A.H., Smith, A.G., Colom, L.V. and Appel, S.H., Apoptotic cell death of a hybrid motoneuron cell line induced by immunoglobulins from patients with amyotrophic lateral sclerosis, J. Neurochem., 63 (1994) 2365-2368.
2. [2] Atabay, C., Kharlamov, E., Cagnoli, C.M., Ikonomovic, D.M. and Manev, H., Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: protection with antioxidants and glutamate receptor antagonists, J. Neurosci. Res., 43 (1996) 465-475.
3. [3] Batistatou, A. and Greene, L.A., Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppresion of endonuclease activity, J. Cell Biol., 115 (1991) 461-471.
4. [4] Beilharz, E.J., Williams, C.E., Dragunow, M., Sirimanne, E.S. and Gluckman, P.D., Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: evidence for apoptosis during selective neuronal loss, Mol. Brain Res., 29 (1995) 1-14.
5. [5] Cadet, L.C., Free radicals and neurodegeneration, Trends Neurosci., 17 (1994) 192-193.
6. [6] Chopp, M., Li, Y., Zhang, Z.G. and Freytag, S.O., p53 expression in brain after middle cerebral artery occlusion in the rat, Biochem. Biophys. Res. Commun., 182 (1992) 1201-1207.
7. [7] Comelli, M.C., Seren, M.S., Guidolin, D., Manev, M.R., Favaron, M., Rimland, J., Canella, R., Negro, A. and Manev, H., Photochemical stroke and brain-derived neurotrophic factor (BDNF) mRNA expression, NeuroReport, 3 (1992) 473-476.
8. [8] Comelli, M.C., Guidolin, D., Seren, M.S., Zanoni, R., Canelli, R., Rubini, R. and Manev, H., Time course, localization and pharmacological characterization of immediate early inducible genes, BDNF and trkB mRNAs in the rat brain following photochemical stroke, Neuroscience, 55 (1993) 473-490.
9. [9] Cohen, G.M., Sun, X.-M., Snowden, R.T., Dinsdale, D. and Skilleter, D.N., Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation, Biochem. J., 286 (1992) 331-334.
10. [10] Crumrine, R.C., Thomas, A.L. and Morgan, P.F., Attenuation of p53 expression protects against focal ischemic damage in transgenic mice, J. Cereb. Blood Flow Metab., 14 (1994) 887-891.
11. [11] Gonzales, R.G., Haxo, R.S. and Schleich, T., Mechanism of action of the polymeric aurintricarboxylic acid, a potent inhibitor of protein-nucleic acid interaction, Biochemistry, 19 (1980) 4299-4303.
12. [12] Hartman, H., Eckert, A. and Muller, W.E., Disturbances of the neuronal calcium homeostasis in the aging nervous system, Life Sci., 55 (1994) 2011-2018.
13. [13] Héron, A., Pollard, H., Dessi, F., Moreau, J., Lasbennes, F., Ben-Ari, Y. and Charriaut-Marlangue, C., Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain, J. Neurochem., 61 (1993) 1973-1976.
14. [14] Ikonomidu, C. and Turski, L., Glutamate in neurodegenerative disorders. In T.W. Stone and B. Pharm (Eds.), CNS Neurotransmitters and Neuromodulators - Glutamate, CRC Press, Boca Raton, FL, 1995, pp. 253-272.
15. [15] Ishimaru, M., Der, T.C., Tenkova, T.I., Sesma, M.A., Thurston, J.H. and Olney, J.W., Three types of excitotoxicity evaluated for 'apoptosis' signals, Soc. Neurosci. Abstr., 21 (1995) 1584.
16. [16] Kharlamov, A., Guidotti, A., Costa, E., Hayes, R. and Armstrong, D., Semisynthetic sphingolipids prevent protein kinase C translocation and neuronal damage in the perifocal area following a photochemically induced thrombotic brain cortical lesion, J. Neurosci., 13 (1993) 2483-2494.
17. [17] Kharlamov, A., Zivkovic, I., Polo, A., Armstrong, D.M., Costa, E. and Guidotti, A., LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit, Proc. Natl. Acad. Sci. USA, 91 (1994) 6303-6307.
18. [18] Kroemer, G., Petit, P., Zamzami, N., Vayssiere, J.-L. and Mignotte, B., The biochemistry of programmed cell death, FASEB J., 9 (1995) 1277-1287.
19. [19] Kubota, Y., The interaction of DNA with Hoechst 33258 studied by fluorescence spectroscopy, Bull. Chem. Soc. Jpn., 63 (1990) 758-764.
20. [20] Kure, S., Tominaga, T., Yoshimoto, T., Tada, K. and Narisawa, K., Glutamate triggers internucleosomal DNA cleavage in neuronal cells, Biochem. Biophys. Res. Commun., 179 (1991) 39-45.
21. [21] Li, Y., Chopp, M., Jiang, N., Zhang, Z.G. and Zaloga, C., Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats, Stroke, 26 (1995) 1252-1258.
22. [22] Linnik, M.D., Zahos, P., Geschwind, M.D. and Federoff, H.J., Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia. Stroke, 26 (1995) 1670-1675.
23. [23] Linnik, M.D., Zobrist, R.H. and Hatfield, M.D., Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats, Stroke, 24 (1993) 2002-2009.
24. [24] Manev, H., Costa, E., Wroblewski, J.T. and Guidotti, A., Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity, FASEB J., 4 (1990) 2789-2797.
25. [25] Manev, H., Kharlamov, A. and Armstrong, D., Photochemical brain injury in rats triggers DNA fragmentation, p53 and HSP72, NeuroReport, 5 (1994) 2661-2664.
26. [26] Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, Sydney, 1982.
27. [27] Portera-Cailliau, C., Hedreen, J.C., Price, D.L. and Koliatsos, V.E., Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models, J. Neurosci., 15 (1995) 3775-3787.
28. [28] Reed, J.C., Bcl-2 and the regulation of programmed cell death, J. CellBiol., 124 (1994) 1-6.
29. [29] Roberts-Lewis, J.M., Marcy, V.R., Zhao, Y., Vaught, J.L., Siman, R. and Lewis, M.E., Aurintricarboxylic acid protects hippocampal neurons from NMDA-and ischemia-induced toxicity in vivo, J. Neurochem., 61 (1993) 378-381.
30. [30] Sakhi, S., Bruce, A., Sun, N., Tocco, G., Baudry, M. and Schreiber, S.S., p53 induction is associated with neuronal damage in the central nervous system, Proc. Natl. Acad. Sci. USA, 91 (1994) 7525-7529.
31. [31] Schreiber, S.S. and Baudry, M., Selective neuronal vulnerability in the hippocampus - a role for gene expression? Trends Neurosci., 18 (1995) 446-451.
32. [32] Schulze-Osthoff, K., Walczak, H., Droge, W. and Kramer, P.H., Cell nucleus and DNA fragmentation are not required for apoptosis, J. Cell Biol., 127 (1994) 15-20.
33. [33] Steller, H., Mechanisms and genes of cellular suicide, Science, 267 (1995) 1445-1449.
34. [34] Su, J.H., Anderson, A.J., Cummings, B.J. and Cotman, C.W., Immunohistochemical evidence for apoptosis in Alzheimer's disease, NeuroReport, 5 (1994) 2529-2533.
35. [35] Thompson, C.B., Apoptosis in the pathogenesis and treatment of disease, Science, 267 (1995) 1456-1462.
36. [36] Watson, D.B., Dietrich, W.D., Busto, R., Wachte, M.S. and Ginsburg, M.D., Induction of reproducible brain infarction by photo-chemically initiated thrombosis, Ann. Neurol., 17 (1985) 497-504.
37. [37] Zeevalk, G.D., Schoepp, D. and Nicklas, W.J., Aurintricarboxylic acid prevents NMDA-mediated excitotoxicity: evidence for its action as an NMDA receptor antagonists, J. Neurochem., 61 (1993) 386-389.