Characterization of mutations contributing to sulfathiazole resistance in Escherichia coli

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 1, 1998, Pages 88-93

  Vedantam, Gayatri ^a,b   Guay, Gordon G ^a,c   Austria, Natasha E ^a   Doktor, Stella Z ^a,d   Nichols, Brian P ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c Gillette Company   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; AMINO ACID; AMPICILLIN; ANTIPORTER; BICOZAMYCIN; DIHYDROPTEROATE SYNTHASE; DNA; KANAMYCIN; NALIDIXIC ACID; NUCLEOTIDE; SULFATHIAZOLE; TETRACYCLINE;

ALLELE; ANTIBIOTIC RESISTANCE; ARTICLE; ESCHERICHIA COLI; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0031982889     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.1.88     Document Type: Article

References (39)

1. Achari, A., D. O. Somers, J. N. Champness, P. K. Bryant, J. Rosemond, and D. K. Stammers. 1997. Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nature Struct. Biol. 4:490-497.
2. Baumstark, B. R., L. L. Spremulli, U. L. RajBhandary, and G. M. Brown. 1977. Initiation of protein synthesis without formylation in a mutant of Escherichia coli that grows in the absence of tetrahydrofolate. J. Bacteriol. 129:457-471.
3. Bentley, J., L. S. Hyatt, K. Ainley, J. H. Parish, R. B. Herbert, and G. R. White. 1993. Cloning and sequence analysis of an Escherichia coli gene conferrring bicyclomycin resistance. Gene 127:117-120.
4. Birnboim, H., and J. Doly. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1513-1523.
5. Blakely, R. L. 1960. Crystalline dihydropteroylglutamic acid. Nature (London) 188:231-232.
6. Brooks, D. R., P. Wang, M. Read, W. M. Watkins, P. F. Sims, and J. E. Hyde. 1994. Sequence variation of the hydroxymethyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to sulfadoxine. Eur. J. Biochem. 224:397-405.
7. Brown, G. M. 1962. The biosynthesis of folic acid. Inhibition by sulfonamides. J. Biol. Chem. 237:536-540.
8. Dallas, W. S., I. K. Dev, and P. H. Ray. 1993. The dihydropteroate synthase gene, folP, is near the leucine tRNA gene, leuU, on the Escherichia coli chromosome. J. Bacteriol. 175:7743-7744.
9. Dallas, W. S., J. E. Gowen, P. H. Ray, M. J. Cox, and I. K. Dev. 1992. Cloning, sequencing, and enhanced expression of the dihydropteroate synthase gene of Escherichia coli MC4100. J. Bacteriol. 174:5961-5970.
10. Fermér, C., B.-E. Kristiansen, O. Sköld, and G. Swedberg. 1995. Sulfonamide resistance in Neisseria meningitidis as defined by site-directed mutagenesis could have its origin in other species. J. Bacteriol. 177:4669-4675.
11. Hafner, E. W., C. W. Tabor, and H. Tabor. 1977. Isolation of a metK mutant with a temperature-sensitive S-adenosylmethionine synthetase. J. Bacteriol. 132:832-840.
12. Hamplele I. C., A. D'Arcy, G. E. Dale, D. Kostrewa, J. Neilsen, C. Oefner, M. G. P. Page, H.-J. Schönfeld, D. Stüber, and R. L. Then. 1997. Structure and function of the dihydropteroate synthase from Staphylococcus aureus. J. Mol. Biol. 268:21-30.
13. Harvey, R. J. 1973. Growth and initiation of protein synthesis in Escherichia coli in the presence of trimethoprim. J. Bacteriol. 114:309-322.
14. Kohara, Y., K. Akiyama, and K. Inoso. 1987. The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50:495-508.
15. Lewis, K. 1994. Multidrug resistance pumps in bacteria: variations on a theme. Trends Biochem. Sci. 19:119-123.
16. Lopez, P., M. Espanosa, B. Greenberg, and S. A. Lacks. 1987. Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene encoding dihydropteroate synthase and characterization of the enzyme. J. Bacteriol. 169:4320-4326.
17. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
18. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
19. Nagy, P. L., A. Marolewski, S. J. Benkovic, and H. Zalkin. 1995. Formyltetrahydrofolate hydrolase, a regulatory enzyme that functions to balance pools of tetrahydrofolate and one-carbon tetrahydrofolate adducts in Escherichia coli. J. Bacteriol. 177:1292-1298.
20. Nagy, P. L., G. M. McCorkle, and H. Zalkin. 1993. purU, a source of formate for purT-dependent phosphoribosyl-N-formylglycinamide synthesis. J. Bacteriol. 175:7066-7073.
21. Nichols, B. P., and G. G. Guay. 1989. Gene amplification contributes to sulfonamide resistance in Escherichia coli. Antimicrob. Agents Chemother. 33:2242-2248.
22. Nichols, B. P., A. Seibold, and S. Z. Doktor. 1989. para-Aminobenzoate synthesis from chorismate occurs in two steps. J. Biol. Chem. 264:8597-8601.
23. Pato, M. L., and G. M. Brown. 1963. Mechanisms of resistance of Escherichia coli to sulfonamides. Arch. Biochem. Biophys. 103:443-448.
24. Pearson, W., and D. Lipman. 1988. Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85:2444-2448.
25. Rådström, P., and G. Swedberg. 1988. RSF1010 and a conjugative plasmid contain sulII, one of two known genes for plasmid-borne sulfonamide resistance dihydropteroate synthase. Antimicrob. Agents Chemother. 32:1684-1692.
26. Rådström, P., C. Fermér, B.-K. Kristiansen, A. Jenkins, O. Sköld, and G. Swedberg. 1992. Transformational exchanges in the dihydropteroate synthase gene of Neisseria meningitidis: a novel mechanism for acquisition of sulfonamide resistance. J. Bacteriol. 174:6386-6393.
27. Richey, D. P., and G. M. Brown. 1969. The biosynthesis of folic acid. IX. Purification and properties of the enzymes required for the formation of dihydropteroic acid. J. Biol. Chem. 244:1582-1592.
28. Roberts, T. M., and G. D. Lauer. 1979. Maximizing gene expression in a plasmid using recombination in vitro. Methods Enzymol. 68:473-482.
29. Roland, S., R. Ferone, R. J. Harvey, V. L. Styles, and R. W. Morrison. 1979. The characteristics and significance of sulfonamides as substrates for Escherichia coli dihydropteroate synthase. J. Biol. Chem. 254:10337-10345.
30. Rudd, K. E. 1992. Alignment of E. coli DNA sequences to a revised, integrated genomic restriction map. In J. H. Miller (ed.), A short course in bacterial genetics: a laboratory manual and handbook for Escherichia coli and related bacteria. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
31. Singer, M., T. A. Baker, G. Schnitzler, S. M. Deischel, M. Goel, W. Dove, K. J. Jaacks, A. D. Grossman, J. W. Erickson, and C. A. Gross. 1989. Collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli. Microbiol. Rev. 53:1-24.
32. Sköld, O. 1976. R-factor-mediated resistance to sulfonamides by a plasmidborne, drug-resistant dihydropteroate synthase. Antimicrob. Agents Chemother. 9:49-54.
33. Slock, J., D. P. Stahly, C.-Y. Han, E. W. Six, and I. P. Crawford. 1990. An apparent Bacillus subtilis folic acid biosynthetic opcron containing pab, an amphibolic trpG gene, a third gene required for synthesis of para-aminobenzoic acid, and the dihydropteroate synthase gene. J. Bacteriol. 172:7211-7226.
34. Sundström, L., P. Rådström, G. Swedberg, and O. Sköld. 1988. Site-specific recombination promotes linkage between trimethoprim- and sulfonamide resistance genes. Sequence characterization of dhfrV and sulI and a recombination active locus of Tn21. Mol. Gen. Genet. 213:191-201.
35. Triglia, T., and A. F. Cowman. 1994. Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 91:7149-7153.
36. Vogel, H., and D. Bonner. 1956. Acetylornithinase of Escherichia coli: partial purification and some properties. J. Biol. Chem. 218:97-106.
37. Volpe, F., S. P. Ballantine, and C. J. Delves. 1993. The multi-functional folic acid synthesis fas gene of Pneumocystis carinii encodes dihydroneopterin aldolase, hydroxymethyl-dihydropterin pyrophosphokinase, and dihydropteroate synthase. Eur. J. Biochem. 216:449-458.
38. Watanabe, W., G.-I. Sampei, A. Aiba, and K. Mizobuchi. 1989. Identification and sequence analysis of Escherichia coli purE and purK genes encoding 5′-phosphoryl-5-amino-4-imidazole carboxylase for de novo purine biosynthesis. J. Bacteriol. 171:198-204.
39. Wilson, K. 1987. Preparation of genomic DNA from bacteria p. 2.4.1-2.4.5. In F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology. Greene Publishing and Wiley-Interscience, New York, N.Y.