-
1
-
-
0028970060
-
Interleukin 12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
-
Trinchieri, G., Interleukin 12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 1995. 13: 251-276.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 251-276
-
-
Trinchieri, G.1
-
2
-
-
0030002111
-
Genetically resistant mice lacking IL-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
-
Martner, F., Magram, J., Ferrante, J., Lanois, P., Dipadova, K., Behin, R., Gately, M. K., Louis, J. A. and Alber, G., Genetically resistant mice lacking IL-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur. J. Immunol. 1996. 26: 1553-1559.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 1553-1559
-
-
Martner, F.1
Magram, J.2
Ferrante, J.3
Lanois, P.4
Dipadova, K.5
Behin, R.6
Gately, M.K.7
Louis, J.A.8
Alber, G.9
-
3
-
-
0027309318
-
Resolution of cutaneous leishmaniasis: Interleukin 12 initiates a protective T helper type 1 immune response
-
Sypek, J. P., Chung, C. L., Mayor, S. E. H., Subramanyan, J. M., Goldman, S. J., Sieburgh, D. S., Wolf, S. F. and Schaub, R. G., Resolution of cutaneous leishmaniasis: Interleukin 12 initiates a protective T helper type 1 immune response. J. Exp. Med. 1993. 177: 1797-1805.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1797-1805
-
-
Sypek, J.P.1
Chung, C.L.2
Mayor, S.E.H.3
Subramanyan, J.M.4
Goldman, S.J.5
Sieburgh, D.S.6
Wolf, S.F.7
Schaub, R.G.8
-
4
-
-
0029076809
-
Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice
-
Heinzel, F. P., Rerko, R. M., Ahmed, F. and Pearlman, E., Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice. J. Immunol. 1995. 155: 730-739.
-
(1995)
J. Immunol.
, vol.155
, pp. 730-739
-
-
Heinzel, F.P.1
Rerko, R.M.2
Ahmed, F.3
Pearlman, E.4
-
5
-
-
0027528795
-
Recombinant Interleukin 12 cures mice infected with Leishmania major
-
Heinzel, F. P., Schoenhaut, D. S., Rerko, R. M., Rosser, L. E. and Gately, M. K., Recombinant Interleukin 12 cures mice infected with Leishmania major. J. Exp. Med. 1993. 177: 1505-1512.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1505-1512
-
-
Heinzel, F.P.1
Schoenhaut, D.S.2
Rerko, R.M.3
Rosser, L.E.4
Gately, M.K.5
-
6
-
-
0028049247
-
The adjuvant effect of Interleukin-12 in a vaccine against Leishmania major
-
Afonso, L. C. C., Scharton, T. M., Vieira, L. Q., Wysocka, M., Trinchieri, G. and Scott, P., The adjuvant effect of Interleukin-12 in a vaccine against Leishmania major. Science 1994. 263: 235-237.
-
(1994)
Science
, vol.263
, pp. 235-237
-
-
Afonso, L.C.C.1
Scharton, T.M.2
Vieira, L.Q.3
Wysocka, M.4
Trinchieri, G.5
Scott, P.6
-
7
-
-
0023151617
-
Parasite-accessory cell interactions in murine leishmaniasis. II. Leishmania donovani suppresses macrophage expression of Class I and Class II major histocompatibility complex gene products
-
Reiner, N. E., Winnie, N. G. and McMaster, W. R., Parasite-accessory cell interactions in murine leishmaniasis. II. Leishmania donovani suppresses macrophage expression of Class I and Class II major histocompatibility complex gene products. J. Immunol. 1987. 138: 1926-1932.
-
(1987)
J. Immunol.
, vol.138
, pp. 1926-1932
-
-
Reiner, N.E.1
Winnie, N.G.2
McMaster, W.R.3
-
8
-
-
0005197276
-
Cutaneous leishmaniasis (oriental score). I. Time required for development of immunity after vaccination
-
Berbarian, D. A., Cutaneous leishmaniasis (oriental score). I. Time required for development of immunity after vaccination. Arch. Dermatol. Syph. 1944. 49: 433-435.
-
(1944)
Arch. Dermatol. Syph.
, vol.49
, pp. 433-435
-
-
Berbarian, D.A.1
-
9
-
-
0005158474
-
Vaccination against oriental score: Report of results of five hundred and fifty-five inoculations
-
Katzenellenbogen, I., Vaccination against oriental score: report of results of five hundred and fifty-five inoculations. Arch. Dermatol. Syph. 1944. 50: 239-242.
-
(1944)
Arch. Dermatol. Syph.
, vol.50
, pp. 239-242
-
-
Katzenellenbogen, I.1
-
10
-
-
0026217940
-
Experimental leishmaniasis in humans; A review
-
Melby, P. C., Experimental leishmaniasis in humans; a review. Rev. Infect. Dis. 1991. 13: 1009-1017.
-
(1991)
Rev. Infect. Dis.
, vol.13
, pp. 1009-1017
-
-
Melby, P.C.1
-
11
-
-
0029147745
-
Characterization of the immune response in subjects with self-healing cutaneous leishmaniasis
-
Carvalho, E. M., Correia Filho, D., Bacellar, O., Almeida, R. P., Essa, H. L. and Rocha, H., Characterization of the immune response in subjects with self-healing cutaneous leishmaniasis. Am. J. Trop. Med. Hyg. 1995. 53: 273-282.
-
(1995)
Am. J. Trop. Med. Hyg.
, vol.53
, pp. 273-282
-
-
Carvalho, E.M.1
Correia Filho, D.2
Bacellar, O.3
Almeida, R.P.4
Essa, H.L.5
Rocha, H.6
-
12
-
-
0027427866
-
In vitro secretion of cytokines by human mononuclear cells of individuals during and after cutaneous leishmaniasis infection
-
Frankenberg, S., Kofsky, Y. and Gross, A., In vitro secretion of cytokines by human mononuclear cells of individuals during and after cutaneous leishmaniasis infection. Parasite Immunol. 1993. 15: 509-512.
-
(1993)
Parasite Immunol.
, vol.15
, pp. 509-512
-
-
Frankenberg, S.1
Kofsky, Y.2
Gross, A.3
-
13
-
-
0028158318
-
Leishmania promastigotes evade Interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection
-
Reiner, S. L., Zheng, S., Wang, Z.-E., Stowring, L. and Locksley, R. M., Leishmania promastigotes evade Interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. J. Exp. Med. 1994. 179: 447-456.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 447-456
-
-
Reiner, S.L.1
Zheng, S.2
Wang, Z.-E.3
Stowring, L.4
Locksley, R.M.5
-
14
-
-
0030911399
-
Endogenous interleukin-12 regulates acquired resistance in experimental visceral leishmaniasis
-
Murray, H. W., Endogenous interleukin-12 regulates acquired resistance in experimental visceral leishmaniasis. J. Infect. Dis. 1997. 175: 1477-1479.
-
(1997)
J. Infect. Dis.
, vol.175
, pp. 1477-1479
-
-
Murray, H.W.1
-
15
-
-
0026357870
-
Natural immunity: A T cell independent pathway of macrophage activation, defined in the scid mouse
-
Bancroft, G. J., Schreiber, R. D. and Unanue, E. R., Natural immunity: a T cell independent pathway of macrophage activation, defined in the scid mouse. Immunol. Rev. 1991. 124: 5-24.
-
(1991)
Immunol. Rev.
, vol.124
, pp. 5-24
-
-
Bancroft, G.J.1
Schreiber, R.D.2
Unanue, E.R.3
-
16
-
-
0026733615
-
Leishmania donovani infection in scid mice: Lack of tissue response and in vivo macrophage activation correlates with failure to trigger natural killer cell-derived gamma interferon production in vitro
-
Kaye, P. M. and Bancroft, G. J., Leishmania donovani infection in scid mice: lack of tissue response and in vivo macrophage activation correlates with failure to trigger natural killer cell-derived gamma interferon production in vitro. Infect. Immun. 1992. 60: 4335-4342.
-
(1992)
Infect. Immun.
, vol.60
, pp. 4335-4342
-
-
Kaye, P.M.1
Bancroft, G.J.2
-
17
-
-
0030298112
-
An in vivo analysis of cytokine production during Leishmania donovani infection in scid mice
-
Engwerda, C. R., Smelt, S. C. and Kaye, P. M., An in vivo analysis of cytokine production during Leishmania donovani infection in scid mice. Exp. Parasitol. 1996. 84: 195-202.
-
(1996)
Exp. Parasitol.
, vol.84
, pp. 195-202
-
-
Engwerda, C.R.1
Smelt, S.C.2
Kaye, P.M.3
-
18
-
-
0030021084
-
Leishmania promastigotes selectively inhibit IL-12 induction in bone-marrow derived macrophages from susceptible and resistant mice
-
Carrera, L., Gazzinelli, R. T., Badolato, R., Hieny, S., Müller, W., Kühn, R. and Sacks, D. L., Leishmania promastigotes selectively inhibit IL-12 induction in bone-marrow derived macrophages from susceptible and resistant mice. J. Exp. Med. 1996. 183: 515-526.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 515-526
-
-
Carrera, L.1
Gazzinelli, R.T.2
Badolato, R.3
Hieny, S.4
Müller, W.5
Kühn, R.6
Sacks, D.L.7
-
19
-
-
0031571866
-
Metacyclogenesis modulates the ability of Leishmania promastigotes to induce IL-12 production in human mononuclear cells
-
Sartori, A., Oliveira, M., Scott, P. and Trinchieri, G., Metacyclogenesis modulates the ability of Leishmania promastigotes to induce IL-12 production in human mononuclear cells. J. Immunol. 1997. 159: 2849-23857.
-
(1997)
J. Immunol.
, vol.159
, pp. 2849-23857
-
-
Sartori, A.1
Oliveira, M.2
Scott, P.3
Trinchieri, G.4
-
20
-
-
0028267766
-
Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of IL-10 in IFN-γ and IL-4 expressing cells
-
Assenmucher, M., Schmitz, J. and Radbruch, A., Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of IL-10 in IFN-γ and IL-4 expressing cells. Eur. J. Immunol. 1994. 24: 1097-1103.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 1097-1103
-
-
Assenmucher, M.1
Schmitz, J.2
Radbruch, A.3
-
21
-
-
0028877056
-
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations
-
Openshaw, P., Murohy, E. E., Hosken, N. A., Maino, V., Davis, K., Murphy, K. and O'Garra, A., Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J. Exp. Med. 1995. 182: 1357-1369.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1357-1369
-
-
Openshaw, P.1
Murohy, E.E.2
Hosken, N.A.3
Maino, V.4
Davis, K.5
Murphy, K.6
O'Garra, A.7
-
22
-
-
0029034014
-
Flow cytometric analysis for cytokine production identifies T helper 1, T helper 2, and T helper 0 cells within the human CD4+ CD27- lymphocyte subpopulation
-
Elson, L., Nutman, T., Metcalfe, D. and Prussin, C., Flow cytometric analysis for cytokine production identifies T helper 1, T helper 2, and T helper 0 cells within the human CD4+ CD27-lymphocyte subpopulation. J. Immunol. 1995. 154: 4294-4302.
-
(1995)
J. Immunol.
, vol.154
, pp. 4294-4302
-
-
Elson, L.1
Nutman, T.2
Metcalfe, D.3
Prussin, C.4
-
23
-
-
15144346540
-
The activated macrophage and granulomatous inflammation
-
Iversen, O. H. (Ed.), Springer, Berlin
-
Adams, D. O. and Hamilton, T. A., The activated macrophage and granulomatous inflammation. In Iversen, O. H. (Ed.), Cell Kinetics of the Inflammatory Reaction, Springer, Berlin 1990, pp 151-167.
-
(1990)
Cell Kinetics of the Inflammatory Reaction
, pp. 151-167
-
-
Adams, D.O.1
Hamilton, T.A.2
-
24
-
-
0029450412
-
Signaling heterogeneity as a contributing factor in macrophage functional diversity
-
Riches, D. H., Signaling heterogeneity as a contributing factor in macrophage functional diversity. Semin. Cell Biol. 1995. 6: 377-384.
-
(1995)
Semin. Cell Biol.
, vol.6
, pp. 377-384
-
-
Riches, D.H.1
-
25
-
-
0026783507
-
Differences in the onset of the inflammatory response to cutaneous leishmaniasis in resistant and susceptible mice
-
Beil, W. J., Meinardus-Hager, G., Neugebauer, D. and Sorg, C., Differences in the onset of the inflammatory response to cutaneous leishmaniasis in resistant and susceptible mice. J. Leukoc. Biol. 1992. 52: 135-142.
-
(1992)
J. Leukoc. Biol.
, vol.52
, pp. 135-142
-
-
Beil, W.J.1
Meinardus-Hager, G.2
Neugebauer, D.3
Sorg, C.4
-
26
-
-
0027967444
-
Transient inducible events in different tissues: In situ studies in the context of the development and expression of the immune responses to intracellular pathogens
-
Belkaid, Y., Bouckson, V., Colle, J.-H., Goossens, P., Lebastard, M., Leclercq, V., Marchal, G., Montixi, C. and Milon, G., Transient inducible events in different tissues: in situ studies in the context of the development and expression of the immune responses to intracellular pathogens. Immunobiology 1994. 191: 413-423.
-
(1994)
Immunobiology
, vol.191
, pp. 413-423
-
-
Belkaid, Y.1
Bouckson, V.2
Colle, J.-H.3
Goossens, P.4
Lebastard, M.5
Leclercq, V.6
Marchal, G.7
Montixi, C.8
Milon, G.9
-
27
-
-
0028359087
-
Infection with Leishmania major induces interleukin-12 production in vivo
-
Vieira, L. Q., Hondowicz, B. D., Afonso, L. C. C., Wysocka, M., Trinchieri, G. and Scott, P., Infection with Leishmania major induces interleukin-12 production in vivo. Immunol. Lett. 1994. 40: 157-161.
-
(1994)
Immunol. Lett.
, vol.40
, pp. 157-161
-
-
Vieira, L.Q.1
Hondowicz, B.D.2
Afonso, L.C.C.3
Wysocka, M.4
Trinchieri, G.5
Scott, P.6
-
28
-
-
0029077326
-
IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
-
Scharton-Kersten, T., Afonso, L. C. C., Wysocka, M., Trinchieri, G. and Scott, P., IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 1995. 154: 5320-5330.
-
(1995)
J. Immunol.
, vol.154
, pp. 5320-5330
-
-
Scharton-Kersten, T.1
Afonso, L.C.C.2
Wysocka, M.3
Trinchieri, G.4
Scott, P.5
-
29
-
-
0031889474
-
Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection
-
Gorak, P., Engwerda, C. R. and Kaye, P., Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection. Eur. J. Immunol. 1998. 28: 687-695.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 687-695
-
-
Gorak, P.1
Engwerda, C.R.2
Kaye, P.3
-
30
-
-
0028262475
-
Impaired interleukin 12 production in human immunodeficiency virus infected patients
-
Chehimi, J., Starr, S. E., Frank, I., D'Andrea, A., Ma, X., MacGregor, R., Sennelier, J. and Trinchieri, G., Impaired interleukin 12 production in human immunodeficiency virus infected patients. J. Exp. Med. 1994. 179: 1361-1366.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1361-1366
-
-
Chehimi, J.1
Starr, S.E.2
Frank, I.3
D'Andrea, A.4
Ma, X.5
MacGregor, R.6
Sennelier, J.7
Trinchieri, G.8
-
31
-
-
0030055867
-
Molecular analysis of decreased interleukin-12 production in persons infected with human immunodeficiency virus
-
Chougnet, C., Wynn, T., Clerici, M., Landay, A., Kessler, H., Rusnak, J., Melcher, G. P., Sher, A. and Shearer, G. M., Molecular analysis of decreased interleukin-12 production in persons infected with human immunodeficiency virus. J. Infect. Dis. 1996. 174: 46-53.
-
(1996)
J. Infect. Dis.
, vol.174
, pp. 46-53
-
-
Chougnet, C.1
Wynn, T.2
Clerici, M.3
Landay, A.4
Kessler, H.5
Rusnak, J.6
Melcher, G.P.7
Sher, A.8
Shearer, G.M.9
-
32
-
-
0029818545
-
Mechanism of suppression of cell-mediated immunity by measles virus
-
Karp, C. L., Wysocka, M., Wahl, L. M., Ahearn, J. M., Cuomo, P. J., Sherry, B., Trinchieri, G. and Griffin, D. E., Mechanism of suppression of cell-mediated immunity by measles virus. Science 1996. 273: 228-231.
-
(1996)
Science
, vol.273
, pp. 228-231
-
-
Karp, C.L.1
Wysocka, M.2
Wahl, L.M.3
Ahearn, J.M.4
Cuomo, P.J.5
Sherry, B.6
Trinchieri, G.7
Griffin, D.E.8
-
33
-
-
0030926583
-
Selective suppression of interleukin-12 induction after macrophage receptor ligation
-
Sutterwala, F. S., Noel, G. J., Clynes, R. and Mosser, D. M., Selective suppression of interleukin-12 induction after macrophage receptor ligation. J. Exp. Med. 1997. 185: 1977-1986.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1977-1986
-
-
Sutterwala, F.S.1
Noel, G.J.2
Clynes, R.3
Mosser, D.M.4
-
34
-
-
0030980385
-
Regulation of interleukin-12 by complement receptor 3 signaling
-
Marth, T. and Kelsall, B., Regulation of interleukin-12 by complement receptor 3 signaling. J. Exp. Med. 1997. 185: 1987-1995.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1987-1995
-
-
Marth, T.1
Kelsall, B.2
-
35
-
-
0024340791
-
CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages
-
da Silva, R. P., Hall, B. F., Joiner, K. A. and Sacks, D. L., CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages. J. Immunol. 1989. 43: 617-622.
-
(1989)
J. Immunol.
, vol.43
, pp. 617-622
-
-
Da Silva, R.P.1
Hall, B.F.2
Joiner, K.A.3
Sacks, D.L.4
-
36
-
-
0027494552
-
The lipophosphoglycan of Leishmania and macrophage protein kinase C
-
Descoteaux, A. and Turco, S. J., The lipophosphoglycan of Leishmania and macrophage protein kinase C. Parasitol. Today 1993. 9: 468-471.
-
(1993)
Parasitol. Today
, vol.9
, pp. 468-471
-
-
Descoteaux, A.1
Turco, S.J.2
-
37
-
-
0029966229
-
Transbilayer inhibition of protein kinase C by the lipophosphoglycan from Leishmania donovani
-
Giorgione, J. R., Turco, S. J. and Epand, E. M., Transbilayer inhibition of protein kinase C by the lipophosphoglycan from Leishmania donovani. Proc. Natl. Acad. Sci. USA 1996. 93: 11634-11639.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11634-11639
-
-
Giorgione, J.R.1
Turco, S.J.2
Epand, E.M.3
-
38
-
-
0021074778
-
Maintenance of granuloma macrophages in serum-free medium
-
Fauve, R. M., Jusforgues, H. and Hevin, B., Maintenance of granuloma macrophages in serum-free medium. J. Immunol. Methods 1983. 64: 345-352.
-
(1983)
J. Immunol. Methods
, vol.64
, pp. 345-352
-
-
Fauve, R.M.1
Jusforgues, H.2
Hevin, B.3
-
39
-
-
0021889262
-
Identification of cell surface carbohydrate and antigenic changes between non infective and infective developmental stages of Leishmania major promastigotes
-
Sacks, D. L., Hieny, S. and Sher, A., Identification of cell surface carbohydrate and antigenic changes between non infective and infective developmental stages of Leishmania major promastigotes. J. Immunol. 1985. 135: 564-569.
-
(1985)
J. Immunol.
, vol.135
, pp. 564-569
-
-
Sacks, D.L.1
Hieny, S.2
Sher, A.3
-
40
-
-
0021059667
-
Isolation and purification of amastigotes of Leishmania mexicana amazonensis by a gradient of metrizamide
-
Saraiva, E. M. B., Pimenta, P., Pereira, M. and DeSouza, W., Isolation and purification of amastigotes of Leishmania mexicana amazonensis by a gradient of metrizamide. J. Parasitol. 1983. 69: 627-629.
-
(1983)
J. Parasitol.
, vol.69
, pp. 627-629
-
-
Saraiva, E.M.B.1
Pimenta, P.2
Pereira, M.3
DeSouza, W.4
-
41
-
-
0020371244
-
Monoclonal antibodies to L. tropica major: Specificities and antigen location
-
de Ibarra, A. A., Howard, J. D. and Snary, D., Monoclonal antibodies to L. tropica major: specificities and antigen location. Parasitology 1982. 85: 523-531.
-
(1982)
Parasitology
, vol.85
, pp. 523-531
-
-
De Ibarra, A.A.1
Howard, J.D.2
Snary, D.3
|