Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea

Molecular and General Genetics

Volumn 257, Issue 5, 1998, Pages 542-553

  Salah Bey, K ^a   Doumith, M ^a   Michel, J M ^a   Haydock, S ^b,c   Cortes J ^b   Leadlay, P F ^b   Raynal, M C ^a  

^a Infectious Disease Group   (France)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Desosamine; Erythromycin biosynthetic genes; Glycosyltransferase; Mycarose; Saccharopolyspora erythraea

Indexed keywords

DEOXYSUGAR; ERYTHROMYCIN; ERYTHRONOLIDE B; GENE PRODUCT; GLYCOSYLTRANSFERASE; ISOMERASE; POLYKETIDE; SYNTHETASE;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIUM MUTANT; CARBOHYDRATE SYNTHESIS; CHROMOSOME MUTATION; CONTROLLED STUDY; DELETION MUTANT; DNA FLANKING REGION; ENZYME ACTIVITY; GENE CLUSTER; GENE LOCUS; GENE TARGETING; MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REACTION ANALYSIS; SACCHAROPOLYSPORA;

AMINO ACID SEQUENCE; AMINO SUGARS; BACTERIAL PROTEINS; CLONING, MOLECULAR; ERYTHROMYCIN; GLYCOSYLTRANSFERASES; HEXOSES; INTRAMOLECULAR OXIDOREDUCTASES; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MULTIGENE FAMILY; MUTAGENESIS; OPEN READING FRAMES; OXIDOREDUCTASES; SACCHAROPOLYSPORA; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0031981439     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050680     Document Type: Article

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