Zinc deficiency suppresses plasma leptin concentrations in rats

Journal of Nutritional Biochemistry

Volumn 9, Issue 1, 1998, Pages 47-51

  Mangian, Heather F ^a   Lee, Rita G ^a   Paul, Gregory L ^a   Emmert, Jason L ^a   Shay, Neil F ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Anorexia; Food intake regulation; Leptin; Rats; Zinc deficiency

Indexed keywords

GLUCOSE; INSULIN; LEPTIN; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ARTICLE; BODY FAT; CONTROLLED STUDY; MALE; NONHUMAN; RAT; ZINC DEFICIENCY;

EID: 0031973394     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-2863(97)00165-4     Document Type: Article

References (38)

1. Campfield L.A., Smith F.J., Guisez Y., Devos R., Burn P. Recombinant mouse OB protein evidence for peripheral signal linking adiposity and central neural networks . Science. 269:1995;546-549.
2. Halaas J.L., Gajiwala K.S., Maffei M., Cohen S.L., Chait B.T., Rabinowitz D., Lallone R.L., Burley S.K., Friedman J.M. Weight-reducing effects of the plasma protein encoded by the obese gene. Science. 269:1995;543-546.
3. Pelleymounter M.A., Cullen M.J., Baker M.B., Hecht R., Winters D., Boone T., Collins F. Effects of the obese gene product on body weight regulation in ob/ob mice. Science. 269:1995;540-543.
4. Tartaglia L.A., Dembski M., Weng X., Deng N., Culpepper J., Devos R., Richards G., Campfield L., Clark F., Deeds J., Muir C., Sanker S., Moriarity A., Moore K., Smutko J., Mays G., Woolf E., Monroe C., Tepper R. Identification and expression cloning of a leptin receptor, OB-R. Cell. 83:1995;1263-1271.
5. Leibowitz S.F. Brain neuropeptide Y An integrator of endocrine, metabolic and behavioral processes . Brain Res. Bull. 27:1991;333-337.
6. Tatemoto K., Mutt V. Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides. Nature. 285:1980;417-418.
7. Erickson J.C., Hollopeter G., Palmiter R.D. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science. 274:1996;1704-1707.
8. Mercer J.G., Hoggard N., Williams L.M., Lawrence C.B., Hannah L.T., Morgan P.J., Trayhurn P. Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus. J. Neuroendo. 8:1996;733-735.
9. Clark J.T., Kalra P., Crowley W., Karla S. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology. 115:1984;427-429.
10. 1-27 injected intracerebroventricularly. Pharmacol. Biochem. Behav. 38:1991;379-384.
11. Stanley B.G., Leibowitz S.F. Neuropeptide Y stimulation of feeding and drinking by injection into the paraventricular nucleus . Life Sciences. 35:1984;2635-2642.
12. Kalra S.P., Dube M.G., Sahu A., Phelps C.P., Kalra P.S. Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food. Proc. Natl. Acad. Sci. 88:1991;10931-10935.
13. Sahu A., Kalra P.S., Kalra S.P. Food deprivation and ingestion induced reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus. Peptides. 9:1988;83-86.
14. Sahu A., White J.D., Kalra P.S., Kalra S.P. Hypothalamic neuropeptide Y gene expression in rats on scheduled feeding regimen. Molec. Brain Res. 15:1992;15-18.
15. Chesters J.K., Quarterman J. Effects of zinc deficiency on food intake and feeding patterns of rats. Br. J. Nutr. 24:1970;1061-1069.
16. Odell B.L., Reeves P.G. Zinc status and food intake. Zinc in Human Biology. Vol. 131:1989;173-181 ILSI Press, Washington, DC USA.
17. Li, G., Tovar-Palacio, C., and Shay, N.F. (1996). Zinc deficiency induced anorexia and hypothalamic neuropeptide Y. FASEB J. 10, 1284 (Abst).
18. Selvais P.L., Labuche C., Ninh N.X., Ketelslegers J.-M., Denef J.-F., Maiter D.M. Cyclic feeding behavior and changes in hypothalamic galanin and neuropeptide Y gene expression induced by zinc deficiency in the rat. J. Neuroendo. 9:1997;55-62.
19. Blanchard R.K., Cousins R.J. Differential display of intestinal mRNAs regulated by dietary zinc. Proc. Natl. Acad. Sci. USA. 93:1996;6863-6868.
20. Tamaki N., Fujimoto-Sakate S., Kikugawa M., Kaneko M., Onosaka S. Analysis of cyclic feed intake in rats fed on a zinc-deficient diet and the level of dihydropyrimidinase. Br. J. Nutr. 73:1995;711-722.
21. Rains T.M., Shay N.F. Zinc status specifically changes preferences for carbohydrate and protein intake in rats self-selecting from separate carbohydrate-, protein-, and fat-containing diets. J. Nutrition. 125:1995;2874-2879.
22. Reeves P.G., Nielsen F.H., Fahey G.C. Purified diets for laboratory rodents final report of the AIN ad hoc writing committee on the reformulation of the AIN76A rodent diet . J. Nutrition. 123:1993;1939-1951.
23. Morgan C.R., Lazaron A. Immunoassay of insulin Two antibody system. Plasma insulin levels in normal, subdiabetic and diabetic rats . Diabetes. 12:1963;115.
24. Mickelsen O., Anderson A.A. A method for preparing intact animals for carcass analyses. J. Lab. Clin. Med. 53:1959;282-290.
25. Folch J., Lees M., Sloane S. A simple method for the isolation and purification of total lipids for animal tissues. J. Biol. Chem. 226:1956;497-509.
26. Zheng D., Jones J.P., Usala S.J., Dohm G.L. Differential expression of ob mRNA in rat adipose tissues in response to insulin. Biochem. Biophys. Res. Commun. 218:1996;434-437.
27. MacDougald O.A., Hwang C.S., Fan H.Y., Lane M.D. Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes. Proc. Natl. Acad. Sci. USA. 92:1995;9034-9037.
28. Saladin R., DeVos P., Guerro-Millo M., Armelle L., Girard J., Stalls B., Auwerx J. Transient increase in obese gene expression after food intake or insulin administration. Letts Nature. 377:1995;527-529.
29. Cusin I., Sainsbury A., Doyle P., Rohner-Jeanrenaud F., Jeanrenaud B. The ob gene and insulin a relationship leading to clues to the understanding of obesity . Diabetes. 44:1995;1467-1470.
30. Gettys T., Harkness P.J., Watson P.M. The β-Adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes. Endocrinology. 137:1996;4054-4057.
31. Keiffer T., Heller R.S., Habener J.F. Leptin receptors expressed on pancreatic β-Cells. Biochem. Biophys. Res. Commun. 224:1996;522-527.
32. Trayhurn P., Duncan J.S., Rayner D.V., Hardie H.J. Rapid inhibition of ob gene expression and circulating leptin levels in lean mice by the β-3-adrenoceptor agonists BRL 35135A and ZD2079. Biochem. Biophys. Res. Commun. 228:1996;605-610.
33. Prasad A.S. Clinical manifestations of zinc deficiency. Ann. Rev. Nutr. 5:1985;341-363.
34. Cioffi J.A., Shafer A.W., Zupancic T.J., Smith-Gbur J., Mikhail A., Platika D., Snodgrass H.R. Novel B219.OB receptor isoforms Possible role of leptin in hematopoesis and reproduction . Nature Med. 2:1996;585-589.
35. Lee G., Proenca R., Montez J.M., Carroll K.M., Darvishzadeh J.G., Lee J.I., Friedman J.M. Abnormal splicing of the leptin receptor in diabetic mice. Nature. 379:1996;632-635.
36. Barash I.A., Cheung C.C., Weigle D.S., Ren H., Kabigting E.B., Kuijper J.L., Clifton D.K., Steiner R.A. Leptin is a metabolic signal to the reproductive system. Endocrinology. 137:1996;3144-3147.
37. Kennedy, K.J., Rains, T.M., and Shay, N.F. (1998). Zinc deficiency changes preferred macronutrient intake in subpopulations of Sprague-Dawley outbred rats and reduces hepatic pyruvate kinase gene expression. J. Nutrition (In press).
38. Pekary A.E., Lukaski H.C., Mena I., Hershman J.M. Processing of TRH precursor peptides in rat brain and pituitary is zinc dependent. Peptides. 12:1991;1025-1032.