-
1
-
-
10144251380
-
Studies on the clinical efficacy of marketed antiepileptic drugs
-
US Government Printing Office, Washington DC
-
Coatsworth JJ (1971) Studies on the clinical efficacy of marketed antiepileptic drugs. NINDS Monograph, Vol. 12. US Government Printing Office, Washington DC
-
(1971)
NINDS Monograph
, vol.12
-
-
Coatsworth, J.J.1
-
2
-
-
0029826744
-
The new generation of antiepileptic drugs: Advantages and disadvantages
-
Perucca E (1996) The new generation of antiepileptic drugs: advantages and disadvantages. Brit J Clin Pharmacol 42: 531-541
-
(1996)
Brit J Clin Pharmacol
, vol.42
, pp. 531-541
-
-
Perucca, E.1
-
3
-
-
7144225772
-
Monotherapy with the new antiepileptic drugs: Test protocols, experience and indications
-
Stefan H (ed) Blackwell Wissenschaft. Berlin (in press)
-
Perucca F, (1998) Monotherapy with the new antiepileptic drugs: test protocols, experience and indications. In: Stefan H (ed) Updates in the treatment of epilepsy. Blackwell Wissenschaft. Berlin (in press)
-
(1998)
Updates in the Treatment of Epilepsy
-
-
Perucca, F.1
-
4
-
-
0027141296
-
Innovative designs of controlled clinical trials in epilepsy
-
Gram L, Schmidt D (1993) Innovative designs of controlled clinical trials in epilepsy. Epilepsia 34 (Suppl 7): 1-6
-
(1993)
Epilepsia
, vol.34
, Issue.7 SUPPL.
, pp. 1-6
-
-
Gram, L.1
Schmidt, D.2
-
6
-
-
0021887675
-
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures
-
Mattson RH, Cramer JA, Collins JF, Smith DB, Delgado-Escueta AV, Browne TR, Williamson PD, Treiman DM, McNamara JO, McCutchen CB, Homan R, Crill WE, Lubozynski MF, Rosenthal NP, Mayersdorf A (1985) Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. New Engl J Med 313: 145-151
-
(1985)
New Engl J Med
, vol.313
, pp. 145-151
-
-
Mattson, R.H.1
Cramer, J.A.2
Collins, J.F.3
Smith, D.B.4
Delgado-Escueta, A.V.5
Browne, T.R.6
Williamson, P.D.7
Treiman, D.M.8
McNamara, J.O.9
McCutchen, C.B.10
Homan, R.11
Crill, W.E.12
Lubozynski, M.F.13
Rosenthal, N.P.14
Mayersdorf, A.15
-
7
-
-
0028956555
-
Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: A randomised comparative monotherapy trial
-
Heller AJ, Chesterman P, Elwes RDC, Crawford P, Chadwick D, Johnson AL, Reynolds EH (1995) Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomised comparative monotherapy trial. J Neurol Neurosurg Psychiatry 58: 44-50
-
(1995)
J Neurol Neurosurg Psychiatry
, vol.58
, pp. 44-50
-
-
Heller, A.J.1
Chesterman, P.2
Elwes, R.D.C.3
Crawford, P.4
Chadwick, D.5
Johnson, A.L.6
Reynolds, E.H.7
-
8
-
-
0029960040
-
Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy
-
De Silva M, MacArdle B, McGowan M, Hughes E, Stewart J, Neville BGR, Johnson AL, Reynolds EH (1996) Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy. Lancet 347: 709-713
-
(1996)
Lancet
, vol.347
, pp. 709-713
-
-
De Silva, M.1
MacArdle, B.2
McGowan, M.3
Hughes, E.4
Stewart, J.5
Neville, B.G.R.6
Johnson, A.L.7
Reynolds, E.H.8
-
9
-
-
0030017195
-
Comparison of phenobarbitone, phenytoin with sodium valproate: Randomized, double-blind study
-
Thilothammal N, Banu K, Ratnam RS (1996) Comparison of phenobarbitone, phenytoin with sodium valproate: randomized, double-blind study. Indian Pediatr 33: 549-555
-
(1996)
Indian Pediatr
, vol.33
, pp. 549-555
-
-
Thilothammal, N.1
Banu, K.2
Ratnam, R.S.3
-
10
-
-
0026794763
-
A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults
-
Mattson RH, Cramer JA, Collins JF, and the Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group (1992) A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. New Engl J Med 327: 765-771
-
(1992)
New Engl J Med
, vol.327
, pp. 765-771
-
-
Mattson, R.H.1
Cramer, J.A.2
Collins, J.F.3
-
12
-
-
0028891208
-
A multicentre comparative trial of sodium valproate and carbamazepine in paediatric epilepsy
-
Verity CM, Hosking G, Easter DJ, on behalf of The Pediatric EPITEG Collaborative Group (1995) A multicentre comparative trial of sodium valproate and carbamazepine in paediatric epilepsy. Dev Med Child Neurol 37: 97-108
-
(1995)
Dev Med Child Neurol
, vol.37
, pp. 97-108
-
-
Verity, C.M.1
Hosking, G.2
Easter, D.J.3
-
13
-
-
0028915864
-
The management of epilepsy in the 1990s. Acquisitions, uncertainties and perspectives for future research
-
Beghi E, Perucca E (1995) The management of epilepsy in the 1990s. Acquisitions, uncertainties and perspectives for future research. Drugs 49: 680-694
-
(1995)
Drugs
, vol.49
, pp. 680-694
-
-
Beghi, E.1
Perucca, E.2
-
14
-
-
0008584463
-
The implicit assumptions of active controlled trials (a critical examination)
-
Leber P (1983) The implicit assumptions of active controlled trials (a critical examination). Control Clin Trials 14: 133
-
(1983)
Control Clin Trials
, vol.14
, pp. 133
-
-
Leber, P.1
-
15
-
-
0024443991
-
Hazards of inference. The active control investigation
-
Leber P (1989) Hazards of inference. The active control investigation. Epilepsia 30: S57-S63
-
(1989)
Epilepsia
, vol.30
-
-
Leber, P.1
-
16
-
-
0025992079
-
Clinical trials of investigational antiepileptic drugs: Monotherapy designs
-
Pledger G, Kramer LD (1991) Clinical trials of investigational antiepileptic drugs: monotherapy designs. Epilepsia 32: 716-731
-
(1991)
Epilepsia
, vol.32
, pp. 716-731
-
-
Pledger, G.1
Kramer, L.D.2
-
17
-
-
0345069847
-
Emerging treatments
-
Richens A, Chadwick D, Mattson RH, Pellock JM (eds) Churchill-Livingstone, Edinburgh (in press)
-
Perucca E, Richens A (1998) Emerging treatments. In: Richens A, Chadwick D, Mattson RH, Pellock JM (eds) A textbook of epilepsy. Churchill-Livingstone, Edinburgh (in press)
-
(1998)
A Textbook of Epilepsy
-
-
Perucca, E.1
Richens, A.2
-
18
-
-
0027420062
-
Felbamate: A double-blind controlled trial in patients undergoing presurgical evaluation of partial seizures
-
Bourgeois B, Leppik IE, Sackellares JC, Laxer K, Lesser R (1993) Felbamate: a double-blind controlled trial in patients undergoing presurgical evaluation of partial seizures. Neurology 43: 693-696
-
(1993)
Neurology
, vol.43
, pp. 693-696
-
-
Bourgeois, B.1
Leppik, I.E.2
Sackellares, J.C.3
Laxer, K.4
Lesser, R.5
-
19
-
-
0028911352
-
Efficacy of felbamate monotherapy in patients undergoing presurgical evaluation of partial seizures
-
Devinsky O, Faught RE, Wilder BJ, Kanner AM, Kamin M, Kramer LD, Rosenberg A (1995) Efficacy of felbamate monotherapy in patients undergoing presurgical evaluation of partial seizures. Epilepsy Res 20: 241-246
-
(1995)
Epilepsy Res
, vol.20
, pp. 241-246
-
-
Devinsky, O.1
Faught, R.E.2
Wilder, B.J.3
Kanner, A.M.4
Kamin, M.5
Kramer, L.D.6
Rosenberg, A.7
-
20
-
-
7144233541
-
Gabapentin (Neurontin) monotherapy in men versus women and in patients receiving previous monotherapy versus those receiving previous polytherapy
-
Lamoreaux L, Garofalo EA, Crockatt JG, and the US Gabapentin Study Group 88/89 (1996) Gabapentin (Neurontin) monotherapy in men versus women and in patients receiving previous monotherapy versus those receiving previous polytherapy. Epilepsia 37 (Suppl 4): 69
-
(1996)
Epilepsia
, vol.37
, Issue.4 SUPPL.
, pp. 69
-
-
Lamoreaux, L.1
Garofalo, E.A.2
Crockatt, J.G.3
-
21
-
-
0342446851
-
Monotherapy trial of oxcarbazepine for partial seizures in hospitalized presurgical patients
-
Schachter SC, Vazquez B, Fisher RS, Laxer KD, Combs Cantrell DT, Montouris GD, Faught E, Willmore LJ, Ojemann LM, Morris GL, Bennett DA (1996) Monotherapy trial of oxcarbazepine for partial seizures in hospitalized presurgical patients. Epilepsia 37 (Suppl 5): 202
-
(1996)
Epilepsia
, vol.37
, Issue.5 SUPPL.
, pp. 202
-
-
Schachter, S.C.1
Vazquez, B.2
Fisher, R.S.3
Laxer, K.D.4
Combs Cantrell, D.T.5
Montouris, G.D.6
Faught, E.7
Willmore, L.J.8
Ojemann, L.M.9
Morris, G.L.10
Bennett, D.A.11
-
22
-
-
0029942451
-
Tiagabine monotherapy in the treatment of partial epilepsy
-
Schachter SC (1995) Tiagabine monotherapy in the treatment of partial epilepsy. Epilepsia 36 (Suppl 6): 2-6
-
(1995)
Epilepsia
, vol.36
, Issue.6 SUPPL.
, pp. 2-6
-
-
Schachter, S.C.1
-
23
-
-
0001143043
-
Vigabatrin as first-line monotherapy in newly diagnosed infantile spasms: A placebo-controlled double-blind trial
-
Peters ACB, Appleton RE, Roy L, Thornton JL (1996) Vigabatrin as first-line monotherapy in newly diagnosed infantile spasms: a placebo-controlled double-blind trial. Epilepsia 3 (Suppl 4): 118
-
(1996)
Epilepsia
, vol.3
, Issue.4 SUPPL.
, pp. 118
-
-
Peters, A.C.B.1
Appleton, R.E.2
Roy, L.3
Thornton, J.L.4
-
24
-
-
0031024282
-
Safety and efficacy of divalproex sodium monotherapy in partial epilepsy: A double-blind, concentration-response design clinical trial
-
Beydoun A, Sachellares JC, Shu V, and the Depakote Monotherapy for Partial Seizures Study Group (1997) Safety and efficacy of divalproex sodium monotherapy in partial epilepsy: a double-blind, concentration-response design clinical trial. Neurology 48: 182-188
-
(1997)
Neurology
, vol.48
, pp. 182-188
-
-
Beydoun, A.1
Sachellares, J.C.2
Shu, V.3
-
25
-
-
0026320316
-
The randomized concentration trial. Evaluation of its sample size efficacy
-
Sanathan LP, Peck CC (1991) The randomized concentration trial. Evaluation of its sample size efficacy. Control Clin Trials 12: 780-794
-
(1991)
Control Clin Trials
, vol.12
, pp. 780-794
-
-
Sanathan, L.P.1
Peck, C.C.2
-
26
-
-
0026662642
-
Felbamute monotherapy: Controlled trial in patients with partial onset seizures
-
Sachdeo R, Kramer LD, Rosenberg A, Sachdeo SK (1992) Felbamute monotherapy: controlled trial in patients with partial onset seizures. Ann Neurol 32: 386-392
-
(1992)
Ann Neurol
, vol.32
, pp. 386-392
-
-
Sachdeo, R.1
Kramer, L.D.2
Rosenberg, A.3
Sachdeo, S.K.4
-
27
-
-
0027536726
-
Felbamate monotherapy for partial-onset seizures: An active control trial
-
Faught E, Sachdeo RC, Remler MP, Chayasirisobhon S, Iragui-Madox VJ (1993) Felbamate monotherapy for partial-onset seizures: an active control trial. Neurology 43: 688-692
-
(1993)
Neurology
, vol.43
, pp. 688-692
-
-
Faught, E.1
Sachdeo, R.C.2
Remler, M.P.3
Chayasirisobhon, S.4
Iragui-Madox, V.J.5
-
28
-
-
7144242528
-
Gabapentin monotherapy: Clinical trial results. from add-on to monotherapy
-
The Hague, September 1-5
-
Garofalo EA (1996) Gabapentin monotherapy: clinical trial results. From add-on to monotherapy (abstract). Satellite Symposium at the 2nd European Congress of Epileptology, The Hague, September 1-5
-
(1996)
Satellite Symposium at the 2nd European Congress of Epileptology
-
-
Garofalo, E.A.1
-
29
-
-
0011779277
-
Topiramate: Double-blind trial as monotherapy
-
Sachdeo SK, Sachdeo RC, Reife RA, Lim P, Pledger G (1995) Topiramate: double-blind trial as monotherapy. Epilepsia 36 (Suppl 4): 33
-
(1995)
Epilepsia
, vol.36
, Issue.4 SUPPL.
, pp. 33
-
-
Sachdeo, S.K.1
Sachdeo, R.C.2
Reife, R.A.3
Lim, P.4
Pledger, G.5
-
30
-
-
0030875699
-
Evaluation of drug treatment outcome in epilepsy: A clinical perspective
-
Perucca E (1997) Evaluation of drug treatment outcome in epilepsy: a clinical perspective. Pharm World Sci 19: 217-222
-
(1997)
Pharm World Sci
, vol.19
, pp. 217-222
-
-
Perucca, E.1
-
31
-
-
0023629575
-
Comparison of oxcarbazepine and carbamazepine: A double-blind study
-
Reinikanen KJ, Keranen T, Halonen T, Komulainen H, Riekkinen PJ (1987) Comparison of oxcarbazepine and carbamazepine: a double-blind study. Epilepsy Res 1: 284-289
-
(1987)
Epilepsy Res
, vol.1
, pp. 284-289
-
-
Reinikanen, K.J.1
Keranen, T.2
Halonen, T.3
Komulainen, H.4
Riekkinen, P.J.5
-
32
-
-
0024494368
-
A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy
-
Dam M, Ekberg R, Lovning Y, Waltimo O. Jacobsen K (1989) A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy. Epilepsy Res 3: 70-77
-
(1989)
Epilepsy Res
, vol.3
, pp. 70-77
-
-
Dam, M.1
Ekberg, R.2
Lovning, Y.3
Waltimo, O.4
Jacobsen, K.5
-
33
-
-
0030805745
-
A double-blind, controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy
-
Bill P, Vigonius U, Pohlmann H, Guerreiro C, Kochen S, Saffer D, Moore A (1997) A double-blind, controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy. Epilepsy Res 27: 195-204
-
(1997)
Epilepsy Res
, vol.27
, pp. 195-204
-
-
Bill, P.1
Vigonius, U.2
Pohlmann, H.3
Guerreiro, C.4
Kochen, S.5
Saffer, D.6
Moore, A.7
-
34
-
-
0343247768
-
A double-blind, controlled clinical trial of oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy
-
Christe W, Kramer G, Vigonius U. Pohlmann H, Steinhoff BJ, Brodie MJ, Moore A (1997) A double-blind, controlled clinical trial of oxcarbazepine versus sodium valproate in adults with newly diagnosed epilepsy. Epilepsy Res 26: 451-460
-
(1997)
Epilepsy Res
, vol.26
, pp. 451-460
-
-
Christe, W.1
Kramer, G.2
Vigonius, U.3
Pohlmann, H.4
Steinhoff, B.J.5
Brodie, M.J.6
Moore, A.7
-
35
-
-
0030796901
-
A double-blind, controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy
-
Guerreiro M, Vigonius U, Pohlmann H, Manreza M, Fejerman N, Antoniuk S, Moore A (1997) A double-blind, controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy. Epilepsy Res 27: 205-213
-
(1997)
Epilepsy Res
, vol.27
, pp. 205-213
-
-
Guerreiro, M.1
Vigonius, U.2
Pohlmann, H.3
Manreza, M.4
Fejerman, N.5
Antoniuk, S.6
Moore, A.7
-
36
-
-
0000083872
-
Comparison of lamotrigine and phenytoin monotherapy in newly diagnosed epilepsy
-
Steiner TJ (1994) Comparison of lamotrigine and phenytoin monotherapy in newly diagnosed epilepsy. Epilepsia 35 (Suppl 8): 31
-
(1994)
Epilepsia
, vol.35
, Issue.8 SUPPL.
, pp. 31
-
-
Steiner, T.J.1
-
37
-
-
0029866895
-
A randomized open multicentre comparative trial of lamotrigine and carbamazepine as monotherapy in patients with newly diagnosed or recurrent epilepsy
-
Reunanen M, Dam M, Yuen AWC (1996) A randomized open multicentre comparative trial of lamotrigine and carbamazepine as monotherapy in patients with newly diagnosed or recurrent epilepsy. Epilepsy Res 23: 149-155
-
(1996)
Epilepsy Res
, vol.23
, pp. 149-155
-
-
Reunanen, M.1
Dam, M.2
Yuen, A.W.C.3
-
38
-
-
0029651761
-
Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy
-
Brodie MJ, Richens A, Yuen AW (1995) Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. Lancet 345: 476-479
-
(1995)
Lancet
, vol.345
, pp. 476-479
-
-
Brodie, M.J.1
Richens, A.2
Yuen, A.W.3
-
39
-
-
0029143292
-
Vigabatrin versus carbamazepine monotherapy in patients with newly diagnosed epilepsy: A randomized controlled study
-
Kalviainen R, Aikia M, Saukkonen AM, Mervaala E, Riekkinen PJ (1995) Vigabatrin versus carbamazepine monotherapy in patients with newly diagnosed epilepsy: a randomized controlled study. Arch Neurol 52: 989-996
-
(1995)
Arch Neurol
, vol.52
, pp. 989-996
-
-
Kalviainen, R.1
Aikia, M.2
Saukkonen, A.M.3
Mervaala, E.4
Riekkinen, P.J.5
-
40
-
-
0006453308
-
Vigabatrin (Sabril) as first-line monotherapy in newly diagnosed epilepsy: A double-blind comparison with carbamazepine
-
Chadwick DW, Roi L, Kennedy KM (1996) Vigabatrin (Sabril) as first-line monotherapy in newly diagnosed epilepsy: a double-blind comparison with carbamazepine. Epilepsia 37 (Suppl 4): 6
-
(1996)
Epilepsia
, vol.37
, Issue.4 SUPPL.
, pp. 6
-
-
Chadwick, D.W.1
Roi, L.2
Kennedy, K.M.3
-
41
-
-
84920299806
-
Gabapentin (Neurontin) as monotherapy in newly diagnosed patients with partial epilepsy: A fixed-dose comparison study versus carbamazepine
-
Chadwick D, Anhut H, Murray G, Greiner M, and the International Gabapentin Monotherapy Study Group 94 077 (1996) Gabapentin (Neurontin) as monotherapy in newly diagnosed patients with partial epilepsy: a fixed-dose comparison study versus carbamazepine. Epilepsia 37 (Suppl 4): 61
-
(1996)
Epilepsia
, vol.37
, Issue.4 SUPPL.
, pp. 61
-
-
Chadwick, D.1
Anhut, H.2
Murray, G.3
Greiner, M.4
-
42
-
-
0030994378
-
Bringing epilepsy out of the shadows
-
Kale R (1997) Bringing epilepsy out of the shadows. Br Med J 315: 2-3
-
(1997)
Br Med J
, vol.315
, pp. 2-3
-
-
Kale, R.1
-
43
-
-
0028152905
-
The cost of epilepsy: A model based on incidence and prognosis
-
Begley CE, Annegers JF, Lairson D, Reynolds T, Hauser WA (1994) The cost of epilepsy: a model based on incidence and prognosis. Epilepsia 35: 1230-1243
-
(1994)
Epilepsia
, vol.35
, pp. 1230-1243
-
-
Begley, C.E.1
Annegers, J.F.2
Lairson, D.3
Reynolds, T.4
Hauser, W.A.5
-
44
-
-
0028129672
-
The cost of epilepsy in the United Kingdom: An estimation based on results from two population based studies
-
Cockerell OC, Hart YM, Sander JWAS, Shorvon SD (1994) The cost of epilepsy in the United Kingdom: an estimation based on results from two population based studies. Epilepsy Res 18: 249-260
-
(1994)
Epilepsy Res
, vol.18
, pp. 249-260
-
-
Cockerell, O.C.1
Hart, Y.M.2
Sander, J.W.A.S.3
Shorvon, S.D.4
|