Genetic instability and cancer

International Journal of Hematology

Volumn 67, Issue 1, 1998, Pages 3-14

  Miyagawa, Kiyoshi ^a  

^a Research Institute for Radiation Biology and Medicine   (Japan)

Author keywords

DNA helicase; Genetic instability; Recombinational repair; The RAD52 epistasis group

Indexed keywords

HELICASE; RECA PROTEIN; RECOMBINANT PROTEIN;

ATAXIA TELANGIECTASIA; BLOOM SYNDROME; CANCER; CANCER SUSCEPTIBILITY; COCKAYNE SYNDROME; EPISTASIS; GENETIC DISORDER; HUMAN; MUTATOR GENE; PRIORITY JOURNAL; PROLYMPHOCYTIC LEUKEMIA; REVIEW; TUMOR SUPPRESSOR GENE; WERNER SYNDROME; XERODERMA PIGMENTOSUM;

EID: 0031961007     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0925-5710(97)00113-8     Document Type: Review

References (44)

1. Ishikawa F. Telomere crisis in leukemia. Int J Hematol. 65:1997;355-364.
2. Sancar A. DNA excision repair. Annu Rev Biochem. 65:1996;43-81.
3. Jiricny J. Mismatch repair and cancer. Cancer Surv. 28:1996;47-68.
4. Troelstra C., van Gool A., de Wit J., Vermeulen W., Bootsma D., Hoeijmakers J.H.J. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell. 71:1992;939-953.
5. Ellis N., Groden J., Ye T.-Z.et al. The Bloom's syndrome gene product is homologous to RecQ helicases. Cell. 83:1995;655-666.
6. Yu C.-E., Oshima J., Fu Y.-H.et al. Positional cloning of the Werner's syndrome gene. Science. 272:1996;258-262.
7. Gray M.D., Shen J.-C., Kamath-Loeb A.S., Blank A., Sopher B.L., Martin G.M., Oshima J., Loeb L.A. The Werner syndrome protein is a DNA helicase. Nature Genet. 17:1997;100-103.
8. Subramanya H.S., Bird L.E., Brannigan J.A., Wigley D.B. Crystal structure of a DExx box DNA helicase. Nature. 384:1996;379-383.
9. Savitsky K., Bar-Shira A., Gilad S.et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science. 268:1995;1749-1753.
10. Barlow C., Hirotsune S., Paylor R.et al. Atm-deficient mice: A paradigm of ataxia telangiectasia. Cell. 86:1996;159-171.
11. Lo Ten Foe J.R., Rooimans M.A., Bosnoyan-Collins L.et al. Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA. Nature Genet. 14:1996;320-323.
12. The Fanconi anaemia/Breast cancer consortium Positional cloning of the Fanconi anaemia group A gene. Nature Genet. 14:1996;324-328.
13. Saar K., Chrzanowska K.H., Stumm M.et al. The gene for the ataxia-telangiectasia variant, Nijmegan breakage syndrome, maps to a 1-cM interval on chromosome 8q21. Am J Hum Genet. 60:1997;605-610.
14. Vorechovsky I., Luo L., Dyer M.J.S.et al. Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukemia. Nature Genet. 17:1997;96-99.
15. Scully R., Chen J., Plug A.et al. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell. 88:1997;265-275.
16. Sharan S.K., Morimatsu M., Albrecht U.et al. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature. 386:1997;804-810.
17. Haber J.E. In vivo biochemistry: physical monitoring of recombination induced by site-specific endonucleases. BioEssays. 17:1995;609-620.
18. Shinohara A., Ogawa H., Matsuda Y., Ushio N., Ikeo K., Ogawa T. Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA. Nature Genet. 4:1993;239-243.
19. Sung P. Catalysis of ATP-dependent homologous DNA paring and strand exchange by yeast RAD51 protein. Science. 265:1994;1241-1243.
20. Baumann P., Benson F.E., West S.C. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell. 87:1996;757-766.
21. Tsuzuki T., Fujii Y., Sakumi K.et al. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc Natl Acad Sci USA. 93:1996;6236-6240.
22. Lim D.-S., Hasty P. A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol Cell Biol. 16:1996;7133-7143.
23. Tashiro S., Kotomura N., Shinohara A., Tanaka K., Ueda K., Kamada N. S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes. Oncogene. 12:1996;2165-2170.
24. Maldonado E., Shiekhattar R., Sheldon M.et al. A human RNA polymerase II complex associated with SRB and DNA-repair proteins. Nature. 381:1996;86-89.
25. Hays S.L., Firmenich A.A., Berg P. Complex formation in yeast double-strand break repair: Participation of Rad51, Rad52, Rad55, and Rad57 proteins. Proc Natl Acad Sci USA. 92:1995;6925-6929.
26. Muris D.F.R., Bezzubova O., Buerstedde J.M.et al. Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination. Mutation Res. 315:1994;295-305.
27. Park M.S. Expression of human RAD52 confers resistance to ionizing radiation in mammalian cells. J Biol Chem. 270:1995;15467-15470.
28. Shen Z., Cloud K.G., Chen D.J., Park M.S. Specific interactions between the human RAD51 and RAD52 proteins. J Biol Chem. 271:1996;148-152.
29. Johnson R.D., Symington L.S. Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57. Mol Cell Biol. 15:1995;4843-4850.
30. Eisen J.A., Sweder K.S., Hanawalt P.C. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucl Acids Res. 23:1995;2715-2723.
31. Gibbons R.J., Picketts D.J., Villard L., Higgs D.R. Mutations in a putative global transcriptional regulator cause X-linked mental retardation with α-thalassemia (ATR-X syndrome). Cell. 80:1995;837-845.
32. Essers J., Hendriks R.W., Swagemakers S.M.A.et al. Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. Cell. 89:1997;195-204.
33. -/- mutant of the chicken DT40 cell line. Cell. 89:1997;185-193.
34. Clever B., Interthal H., Schmuckli-Maurer J., King J., Sigrist M., Heyer W.-D. Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins. EMBO J. 16:1997;2535-2544.
35. Golub E.I., Kovalenko O.V., Gupta R.C., Ward D.C., Radding C.M. Interaction of human recombination proteins Rad51 and Rad54. Nucl Acid Res. 25:1997;4106-4110.
36. Ajimura M., Leem S.-H., Ogawa H. Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae. Genetics. 133:1993;51-66.
37. Petrini J.H.J., Walsh M.E., DiMare C., Chen X.-N., Korenberg J.R., Weaver D.T. Isolation and characterization of the human MRE11 homologue. Genomics. 29:1995;80-86.
38. Xiao Y., Weaver D.T. Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells. Nucl Acid Res. 25:1997;2985-2991.
39. Alani E., Padmore R., Kleckner N. Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination. Cell. 61:1990;419-436.
40. Dolganov G.M., Maser R.S., Novikov A., Tosto L., Chong S., Bressan D.A., Petrini J.H.J. Human Rad50 is physically associated with human Mre11: Identification of a conserved multiprotein complex implicated in recombinational DNA repair. Mol Cell Biol. 16:1996;4832-4841.
41. Baker S.M., Bronner C.E., Zhang L.et al. Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell. 82:1995;309-319.
42. de Wind N., Dekker M., Berns A., Radman M., te Riele H. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell. 82:1995;321-330.
43. Edelmann W., Cohen P.E., Kane M.et al. Meiotic pachytene arrest in MLH1-deficient mice. Cell. 85:1996;1125-1134.
44. Richards B., Zhang H., Phear G., Meuth M. Conditional mutator phenotypes in hMSH2-deficient tumor cell lines. Science. 277:1997;1523-1526.