Antigenic stimulation by BCG vaccine as an in vivo driving force for SIV replication and dissemination

Nature Medicine

Volumn 4, Issue 4, 1998, Pages 421-427

  Cheynier, Rémi ^a   Gratton, Sophie ^a   Halloran, Matilda ^b   Stahmer, Ingrid ^a,c   Letvin, Norman L ^b   Wain Hobson, Simon ^a  

^a INSTITUT PASTEUR   (France)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CD4 ANTIGEN; CD8 ANTIGEN; TUBERCULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; IMMUNOSTIMULATION; INTRAVENOUS DRUG ADMINISTRATION; LYMPHOCYTE CLONE; LYMPHOID TISSUE; MONKEY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE; VIRUS REPLICATION; VIRUS TRANSMISSION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BCG VACCINE; DNA PRIMERS; EYELIDS; GENE PRODUCTS, ENV; GENE REARRANGEMENT, T-LYMPHOCYTE; HYPERSENSITIVITY, DELAYED; MACACA MULATTA; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PHYLOGENY; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES; VARIATION (GENETICS); VIRUS REPLICATION;

ANIMALIA; MYCOBACTERIUM; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM TUBERCULOSIS; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0031948463     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0498-421     Document Type: Article

References (38)

1. McIlroy, D., et al. Infection frequency of dendritic cells and CD4+ T lymphocytes in spleens of human immunodeficiency virus-positive patients. J. Virol. 69, 4737-4745 (1995).
2. Schnittman, S.M. et al. Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc. Natl. Acad. Sci. USA 87, 6058-62 (1990).
3. Zack, J.A., et al. HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell 61, 213-222 (1990).
4. Gaynor, R.B. Regulation of HIV-1 gene expression by the transactivator protein. Curr. Top. Microbiol. Immunol. 193, 51-77 (1995).
5. Claydon, E.J., Bennett, J., Gor, D. & Forster, S.M. Transient elevation of serum HIV-1 antigen levels associated with intercurrent infection. AIDS 5, 113-114 (1991).
6. Fultz, P.N., Gluckman, J.C., Muchmore, E. & Girard, M. Transient increases in numbers of infectious cells in an HIV-1 infected chimpanzee following immune activation. AIDS Res. Hum. Retroviruses 8, 313-317 (1992).
7. Brichacek, B., Swindells, S., Janoff, E.N., Pirruccello, S. & Stevenson, M. Increased plasma human immunodeficiency virus type 1 burden following antigenic challenge with pneumococcal vaccine. J. Infect. Dis. 174, 1191-9 (1996).
8. Ho, D.D. HIV-1 viremia and influenza. Lancet 339, 1549 (1992).
9. O'Brien, W.A. et al. Human immunodeficiency virus type 1 replication can be increased in peripheral blood of seropositive patients after influenza vaccination. Blood 86, 1082-1089 (1995).
10. Stanley, S.K. et al. Effect of immunization with a common recall antigen on viral expression in patients infected with human immunodeficiency virus type 1. N. Engl. J. Med. 334, 122-1230 (1996).
11. Staprans, S.I. et al. Activation of virus replication after vaccination of HIV-1 infected individuals. J. Exp. Med. 182, 1727-1737 (1995).
12. Cheynier, R. et al. HIV and T cell expansion in splenic white pulps is accompanied by infiltration of HIV-specific cytotoxic T lymphocytes. Cell 78, 373-87 (1994).
13. Levy, J.A. The value of primate models for studying human immunodeficiency virus pathogenesis. J. Med. Primatol. 25, 163-74 (1996).
14. Pelletier, E., Saurin, W., Cheynier, R., Letvin, N.L. & Wain-Hobson, S. The tempo and mode of SIV quasispecies development in vivo calls for massive viral replication and clearance. Virology 208, 644-652 (1995).
15. Wain-Hobson, S. Viral burden and AIDS. Nature 366, 22 (1993).
16. Burns, D.P.W. & Desrosiers, R.C. Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys. J. Virol. 65, 1843-1854 (1991).
17. Kuramoto, Y., Sekita, Y. & Tagami, H. Histoanalytical study of the cellular infiltrate in the tuberculin reaction. Clin. Exp. Dermatol. 18, 111-118 (1993).
18. Bleavins, M.R. & de la Iglesia, F.A. Cynomologous monkeys (Macaca fascicularis) in preclinical immune function safety testing: development of a delayed-type hypersensitivity procedure. Toxicology 95, 103-112 (1995).
19. Pilkington, C., Costello, A.M., Rook, G.A. & Stanford, J.L. Development of IgG responses to mycobacterial antigens. Arch. Dis. Child. 69, 644-9 (1993).
20. Rota, S., Beyazova, U., Karsligil, T. & Cevheroglu, C. Humoral immune response against antigen 60 in BCG-vaccinated infants. Eur. J. Epidemiol. 10, 713-8 (1994).
21. Chen, Z.W., Yamamoto, H., Watkins, D.I., Levinson, G. & Letvin, N.L. Predominant use of a T-cell receptor Vβ gene family in simian immunodeficiency virus gag-specific cytotoxic T lymphocytes in a rhesus monkey. J. Virol. 66, 3913-3917 (1992).
22. Chen, Z.W., Kou, Z.-C., Shen, L., Reimann, K.A. & Letvin, N.L. Conserved T-cell receptor repertoire in simian immunodeficiency virus-infected rhesus monkeys. J. Immunol. 151, 2177-2187 (1993).
23. Bandelt, H.J. & Dress, A.W.M. Split decomposition: a new and useful approach to phylogenetic analysis of distance data. Mol. Phylogenet. Evol. 1, 242-252 (1992).
24. Dopazo, J., Dress, A.W.M. & von Haeseler, A. Split decomposition: a new technique to analyse viral evolution. Proc. Natl. Acad. Sci. USA 90, 10320-10324 (1993).
25. Mansky, L.M. & Temin, H.M. Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J. Virol. 69, 5087-5094 (1995).
26. Ravn, P., Boesen, H., Pedersen, B.K. & Andersen, P. Human T cell responses induced by vaccination with Mycobacterium bovis Bacillus Calmette-Guérin. J. Virol. 158, 1949-1955 (1997).
27. Weissman, D., Barker, T.D. & Fauci, A.S. The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation. J. Exp. Med. 183, 687-692 (1996).
28. Dittmer, U., Niblein, T., Meyerhans, A., Hunsmann, G. & Stahl-Henning, C. No reactivation of attenuated immunodeficiency viruses in macaques after vaccinia virus-induced immune activation. J. Gen. Virol. 78, 2523-2528 (1997).
29. Kreiss, J. et al. Association between cervical inflammation and cervical shedding of human immunodeficiency virus DNA. J. Infect. Dis. 170, 1597-1601 (1994).
30. Galai, N., Kalinkovich, A., Burstein, R., Vlahov, D. & Bentwich, Z. African HIV-1 subtype C and rate of progression among Ethiopian immigrants in Israel. Lancet 349, 180-181 (1997).
31. Bentwich, Z., Kalinkovich, A. & Weisman, Z. Immune activation is a dominant factor in the pathogenesis of African AIDS. Immunol. Today 16, 187-191 (1995).
32. Gerna, G. et al. Sharp drop in the prevelance of human cytomegalovirus leukoDNAemia in HIV-infected patients following highly active antiretroviral therapy. AIDS 12, 118-119 (1998).
33. Chun, T.-W. et al. Quantitation of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387, 183-188 (1997).
34. Finzi, D. et al. Identification of a reservoir for HIV-1 in patients on highly active anti-retroviral therapy. Science 278, 1295-1300 (1997).
35. Perelson, A.S. et al. Decay characteristics of HIV-1 infected conpartments and implications for eradication. Nature 387, 188-191 (1997).
36. Wong, J.K. et al. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 278, 1291-1295 (1997).
37. Cheynier, R. Henrichwark, S. & Wain-Hobson, S. Sequence of the rhesus monkey T-cell receptor β chain diversity and joining loci. Immunogenet. 43, 83-87 (1996).
38. Cheng, S., Fockler, C., Barnes, W.M. & Higuchi, R. Effective amplification of long targets from cloned inserts and human genomic DNA. Proc. Natl. Acad. Sci. USA 91, 5695-5699 (1994).