Short-chain fatty acids in ulcerative colitis

Nutrition Reviews

Volumn 56, Issue 1 I, 1998, Pages 17-24

  Kim, Young In ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; BUTYRIC ACID; CORTICOSTEROID; MESALAZINE; PROPIONIC ACID; SALAZOSULFAPYRIDINE; SHORT CHAIN FATTY ACID;

ANAEROBIC METABOLISM; CARBOHYDRATE METABOLISM; CLINICAL TRIAL; COLON; COLON MUCOSA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST CONTROL; DISEASE SEVERITY; ENERGY RESOURCE; FATTY ACID OXIDATION; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; META ANALYSIS; ORAL DRUG ADMINISTRATION; REVIEW; TREATMENT OUTCOME; ULCERATIVE COLITIS;

EID: 0031939532     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1753-4887.1998.tb01654.x     Document Type: Review

References (40)

1. Jewell DP. Ulcerative colitis. In: Sleisenger MH, Fordtran JS, eds. Gastrointestinal disease: pathophysiology/diagnosis/management. Philadelphia: WB Saunders, 1993;1305-30
2. Hanauer SB. Inflammatory bowel disease. N Engl J Med 1996;334:841-8
3. Gionchetti P, Campieri M. Medical treatment of ulcerative colitis. Curr Opin Gastroenterol 1996;12:352-5
4. Marshall JK, Irvine EJ. Rectal corticosteroids versus alternative treatments in ulcerative colitis: a meta-analysis. Gut 1997;40:775-81
5. Bitton A, Peppercorn MA. Medical therapy of ulcerative proctitis and proctosigmoiditis, including refractory disease, Inflamm Bowel Dis 1995;1:207-19
6. Greenberg GR. Nutritional support in inflammatory bowel disease: current status and future directions. Scand J Gastroenterol 1992;27(suppl)192:117-22
7. Kim Y-I. Can fish oil maintain Crohn's disease in remission? Nutr Rev 1996;54:248-57
8. Bugaut M. Occurrence, absorption and metabolism of short-chainfatty acids in the digestive tract of mammals. Comp Biochem Physiol 1987;86B:439-72
9. Rowe WA, Bayless TM. Colonic short-chain fatty acids: fuel from the lumen? Gastroenterology 1992;103:336-9
10. Roediger WEW. Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology 1982;83:424-9
11. McNeil NI. The contribution of the large intestine to energy supplies in man. Am J Clin Nutr 1984;39:338-42
12. Binder HJ, Mehta P. Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon. Gastroenterology 1989;96:989-96
13. Roediger WEW. Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut 1980;21:793-8
14. Roediger WEW. The colonic epithelium in ulcerative colitis: an energy-deficiency disease. Lancet 1980;2:712-5
15. Vernia P, Gnaedinger A, Hauck W, Breuer RI. Organic anions and the diarrhea of inflammatory bowel disease. Dig Dis Sci 1988;33:1353-8
16. Roediger WEW, Heyworth M, Willoughby P, et al. Luminal ions and short-chainfatty acids as markers of functional activity of the mucosa in ulcerative colitis. J Clin Pathol 1982;35:323-6
17. Treem WR, Naheedt A, Shoup M, Hyams JS. Fecal short-chain fatty acids in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1994;18:159-64
18. Roediger WEW, Duncan A, Kapaniris O, Millard S. Reducing sulfur compounds of the colon impair colonocyte nutrition: implications for ulcerative colitis. Gastroenterology 1993;104;802-9
19. Roediger WEW, Duncan A, Kapaniris O, Millard S. Sulfide impairment of substrate oxidation in rat colonocytes: a biochemical basis for ulcerative colitis? Clin Sci 1993;85:623-7
20. Harig JM, Soergel KH, Komorowski RA, Wood CM. Treatment of diversion colitis with short-chain fatty acid irrigation. N Engl J Med 1989;320:23-8
21. Glotzer DJ, Glick ME, Goldman H. Proctitis and colitis following diversion of the fecal stream. Gastroenterology 1981;80:438-41
22. Guillemot F, Colombel JF, Neut C, et al. Treatment of diversion colitis by short-chain fatty acids. Dis Colon Rectum 1991;34:861-4
23. Schouten WR, Duisters MM, Briel JW, ten Kate FJW. Short-chain fatty acid irrigation in the treatment of proctitis in excluded rectal segments. Falk Symposium No 73, Strasbourg, September 8-10, 1993; Abstract D5
24. Breuer RI, Buto SK, Christ ML, et al. Rectal irrigation with short-chain fatty acids for distal ulcerative colitis: preliminary report. Dig Dis Sci 1991;36:185-7
25. Steinhart AH, Brzezinski A, Baker JP. Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas. Am J Gastroenterol 1994;89:179-83
26. Vernia P, Cittadini M, Caprilli R, Torsoli A. Topical treatment of refractory distal ulcerative colitis with 5-ASA and sodium butyrate. Dig Dis Sci 1995;40:305-7
27. Patz J, Jacobsohn WZ, Gottschalk-Sabag S, et al. Treatment of refractory distal ulcerative colitis with short-chain fatty acid enemas. Am J Gastroenterol 1996;91:731-4
28. Scheppach W, Sommer H, Kirchner T, et at. Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis. Gastroenterology 1992;103:51-6
29. Senagore AJ, Mackeigan JM, Scheider M, Ebrom S. Short-chain fatty acid enemas: a cost effective alternative in the treatment of nonspecific proctosigmoiditis. Dis Colon Rectum 1992;35:923-7
30. Venia P, Marcheggiano A, Caprilli R, et al. Short-chain fatty acid topic treatment in distal ulcerative colitis. Aliment Pharmacol Ther 1995;9:309-13
31. Steinhart AH, Hiruki T, Brezezinski A, Baker JP Treatment of left-sided ulcerative colitis with butyrate enemas: a controlled trial. Aliment Pharmacol Ther 1996;10:729-36
32. Scheppach W, German-Austrian SCFA Study Group. Treatment of distal ulcerative colitis with short-chain fatty acid enemas: a placebo-controlled trial. Dig Dis Sci 1996;41:2254-9
33. Breuer RI, Soergel KH, Lashner BA, et al. Short-chain fatty acid rectal irrigation for left-sided ulcerative colitis: a randomized, placebo-controlled trial. Gut 1997;40:485-91
34. Scheppach W, Bartram HP, Richter F. Role of short-chain fatty aids in the prevention of colorectal cancer. Eur J Cancer 1995;31:1077-80
35. Ekbom AM. Cancer risk in inflammatory bowel disease. Can J Gastroenterol 1995;9:23-6
36. Kripke SA, Fox AD, Berman JM, et al. Stimulation of intestinal mucosal growth with intracolonic infusion of short-chain fatty acids. JPEN 989;13:109-16
37. Sakata T. Effects of short-chain fatty acids on epithelial cell proliferation and mucus release in the intestine. In: Roche AF, ed. Short-chain fatty acids: metabolism and clinical importance. Report of the 10th Ross Conference on Medical Research. Columbus, OH: Ross Laboratories, 1991;63-7
38. Kvietys PR, Granger DN. Effect of volatile fatty acids on blood flow and oxygen uptake by the dog colon. Gastroenterology 1981;80:962-9
39. Mortensen FV, Nielsen H, Mulvany MJ, Hessov I. Short-chain fatty acids dilate isolated human colonic resistance arteries. Gut 1990;31:1391-4
40. D'Argenio G, Cosenza V, Sorrentini I, et al. Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: effects on transglutaminase activity. Gastroenterology 1994;106:399-404