A novel rat tyrosine hydroxylase mRNA species generated by alternative splicing

Journal of Neurochemistry

Volumn 66, Issue 5, 1996, Pages 1819-1825

  Lanièce, Philippe ^a   Le Hir, Hervé ^b   Bodeau Péan, Sylvie ^c   Charon, Yves ^a   Valentin, Luc ^a   Thermes, Claude ^b   Mallet, Jacques ^c   Dumas, Sylvie ^c  

^a Orsay Campus   (France)

^b CNRS   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Adrenal medulla; Alternative splicing; Rat; Tyrosine hydroxylase; Tyrosine hydroxylase mRNA species; Tyrosine hydroxylase regulation

Indexed keywords

MESSENGER RNA; TYROSINE 3 MONOOXYGENASE;

ADRENAL MEDULLA; ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DROSOPHILA; ENZYME ACTIVITY; ENZYME REGULATION; EXON; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SUBSTANTIA NIGRA;

ANIMALIA; PRIMATES;

EID: 0029875467     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66051819.x     Document Type: Article

References (37)

1. Abate C. and Job T. H. (1991) Limited proteolysis of rat brain tyrosine hydroxylase defines an N-terminal region required for regulation of cofactor binding and directing substrate specificity. J. Mol. Neurosci. 2, 203-215.
2. Baruchin A., Weisberg E. P., Miner L. L., Ennis D., Nisenbaum L. K., Naylor E., Stricker E. M., Zigmond M. J., and Kaplan B. B. (1990) Effects of cold exposure on rat adrenal tyrosine hydroxylase, an analysis of RNA, protein, enzyme activity and cofactor levels. J. Neurochem. 54, 1769-1775.
3. Birman S., Morgan B., Anzivino M., and Hirsh J. (1994) A novel and major isoform of tyrosine hydroxylase in Drosophila is generated by alternative RNA processing. J. Biol Chem. 269, 1-9.
4. Bonnefoy E., Ferrara P., Rohrer H., Gros F., and Thibault J. (1988) Role of the N-terminus of rat pheochromocytoma tyrosine hydroxylase in the regulation of the enzyme's activity. Eur. J. Biochem. 174, 685-690.
5. Campbell D. G., Hardie D. G., and Vulliet P. R. (1986) Identification of four phosphorylation sites in the N-terminal region of tyrosine hydroxylase. J. Biol. Chem. 261, 10489-10492.
6. Cervini R., Berrard S , Bejanin S., and Mallet J. (1994) Regulation by CDF/LIF and retinoic acid of multiple chAT mRNAs produced from distinct promoters. Neuroreport 5, 1346-1348.
7. Coker G. T. III, Studelska D., Harmon S., Burke W., and O'Malley K. L. (1990) Analysis of tyrosine hydroylase and insulin transcripts in human neuroendocrine tissues. Mol. Brain Res. 8, 93-98.
8. Daubner S. C., Lohse D. L., and Fitzpatrick P. F. (1993) Characterization of catalytic and regulatory domains of rat tyrosine hydroxylase. Protein Sci. 2, 1452-1460.
9. D'Mello S. R , Weisberg E. P., Stachowiak M. D., Turzai L. M., Gioi A. E., and Kaplan B. B. (1988) Isolation and nucleotide sequence of a cDNA clone encoding bovine adrenal tyrosine hydroxylase: comparative analysis of tyrosine hydroxylase gene products. J. Neurosci. Res. 19, 440-449.
10. Dumas S., Horellou P., Helin C., and Mallet J. (1992) Co-expression of tyrosine hydroxylase messenger RNA 1 and 2 in human ventral mesencephalon revealed by digoxigenin- and biotin-labelled oligodeoxyribonucleotides. J. Chem. Neuroanat. 5, 11-18.
11. Fauquet M., Grima B., Lamouroux A., and Mallet J. (1988) Cloning of quail tyrosine hydroxylase: amino acid homology with other hydroxylases discloses functional domains. J. Neurochem. 50, 142-148
12. Goldstein M. (1995) Long- and short-term regulation of tyrosine hydroxylase, in Psychopharmacology: The Fourth Generation of Progress (Bloom F E. and Kupfer D. J., eds), pp. 189-195. Raven Press, New York.
13. Grima B., Lamouroux A., Blanot F., Faucon-Biguet N., and Mallet J. (1985) Complete coding sequence of rat tyrosine hydroxylase mRNA. Proc. Natl. Acad. Sci. USA 82, 617-621.
14. Grima B., Lamouroux A., Boni C., Julien J. F., Javoy-Agid F., and Mallet J. (1987) A single human gene encoding multiple tyrosine hydroxylase with different predicted functional characteristics. Nature 326, 707-711.
15. 40. Neurochem. Res. 18, 15-26.
16. Higushi R. (1989) PCR Technology, Principles and Applications for DNA Amplification (Erlich H. A., ed), pp. 61-70. Stockton Press, New York.
17. Horellou P., Le Bourdellès B., Clot-Humbert J., Guibert B., Leviel V., and Mallet J. (1988) Multiple human tyrosine hydroxylase enzymes, generated through alternative splicing, have different specific activities in Xenopus oocytes. J. Neurochem. 51, 652-655.
18. Ichikawa S., Ichinose H., and Nagatsu T (1990) Multiple mRNAs of monkey tyrosine hydroxylase. Biochem. Biophys. Res. Commun. 173, 1331-1336.
19. Ichikawa S., Sasaoka T., and Nagatsu T. (1991) Primary structure of mouse tyrosine hydroxylase deduced from its cDNA. Biochem. Biophys. Res. Commun. 176, 1610-1616.
20. Ichinose H., Ohye T., Fujita K., Yoshida M., Ueda S., and Nagatsu T. (1993) Increased heterogeneity of TH in humans. Biochem. Biophys. Res. Commun. 195, 158-165.
21. Johnston R. F., Pickett S. C., and Barker D. L. (1990) Autoradiography using storage phosphor technology. Electrophoresis 11, 355-360.
22. Kaneda N., Kobayashi K., Ichinose H., Kishi F., Nakazawa A., Kurosawa Y., Fujita K., and Nagatsu T. (1987) Isolation of a novel cDNA clone for human tyrosine hydroxylase: alternative RNA splicing produces four kinds of mRNA from a single gene. Biochem. Biophys. Res. Commun. 146, 971-975.
23. Kedzierski W. and Porter J. C. (1990) Quantitative study of tyrosine hydroxylase mRNA in catecholaminergic neurons and adrenals during development and aging. Mol. Brain Res. 7, 45-51.
24. Kobayashi K., Kaneda Y., Ichinose H., Kishi F., Nakazawa A., Kurosawa Y., Fujita K., and Nagatsu T. (1988a) Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA types. J. Biochem. (Tokyo) 103, 907-912.
25. Kobayashi K., Kiuchi K., Ishii A., Kaneda N., Kurosawa Y., Fujita K., and Nagatsu T. (1988b) Expression of four types of human tyrosine hydroxylase in COS cells. FEBS Lett. 238, 431-434.
26. Lanièce P., Charon Y., Dumas S., Mastrippolito R., Pinot R., Tricoire H., and Valentin L. (1994) HRRI: a high resolution radioimager for fast, direct quantification in in situ hybridization experiments. Biotechniques 17, 338-344.
27. Lebourdellès B., Boularand S., Boni C., Horellou P., Dumas S., Grima B., and Mallet J. (1988) Analysis of the 5′ region of human tyrosine hydroxylase gene: combinatorial patterns of exon splicing generate multiple regulated tyrosine hydroxylase isoforms. J. Neurochem. 50, 988-991.
28. Lebourdellès B., Horellou P., Le Caer J. P., Denèfle P., Latta M., Haavik J., Guibert B., Mayaux J. F., and Mallet J. (1991) Phosphorylation of human recombinant tyrosine hydroxylase isoforms 1 and 2: an additional phosphorylated residue in isoform 2, generated through alternative splicing. J. Biol. Chem. 266, 17124-17130.
29. Lewis D. A., Melchitzky D. S., and Haycock J. W. (1993) Four isoforms of tyrosine hydroxylase are expressed in human brain. Neuroscience 54, 477-492.
30. Nagatsu T. (1991) Genes for human catecholamine-synthesizing enzymes. Neurosci. Res. 12, 315-345.
31. Nagatsu T. and Ichinose H. (1991) Comparative studies on the structure of human tyrosine hydroxylase with those of the enzyme of various mammals. Comp. Biochem. Physiol. 98, 203-210.
32. Nasrin S., Ichinose H., Hidaka H., and Nagatsu T. (1994) Recombinant human tyrosine hydroxylase types 1-4 show regulatory kinetic properties for the natural (6R)-tetrahydrobiopterin cofactor. J. Biochem. (Tokyo) 116, 393-398.
33. Neckameyer W. S. and Quinn W. G. (1989) Isolation and characterization of the gene for Drosophila tyrosine hydroxylase. Neuron 2, 1167-1175.
34. Ribeiro P., Wang Y., Citron B. A., and Kaufman S. (1993) Deletion mutagenesis of rat PC12 tyrosine hydroxylase regulatory and catalytic domains. J. Mol. Neurosci. 4, 125-139.
35. Strong R., Moore M. A., Hale C., Wessels-Reiker M., Armbrecht H. J., and Richardson A. (1990) Modulation of tyrosine hydroxylase gene expression in the rat adrenal gland by age and reserpine. Brain Res. 525, 126-132.
36. Walker J. S., Liu X., Roskoski R., and Vrana K. E. (1994) Catalytic core of rat tyrosine hydroxylase: terminal deletion analysis of bacterially expressed enzyme. Biochim. Biophys. Acta 1206, 113-119.
37. Zigmond R. E. (1985) Biochemical consequences of synaptic stimulation. The regulation of tyrosine hydroxylase activity by multiple transmitters. Trends Neurosci. 8, 63-69.