Paraoxonase has a major role in the hydrolysis of prulifloxacin (NM441), a prodrug of a new antibacterial agent

Drug Metabolism and Disposition

Volumn 26, Issue 4, 1998, Pages 355-359

  Tougou, Katsuhiko ^a   Nakamura, Akio ^b   Watanabe, Shuji ^b   Okuyama, Yoshio ^b   Morino, Akira ^b  

^a NIPPON SHINYAKU CO LTD   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARYLESTERASE; PRULIFLOXACIN;

AMINO ACID SEQUENCE; ANION EXCHANGE; ARTICLE; CATALYSIS; DRUG HYDROLYSIS; DRUG PROTEIN BINDING; ENZYME ACTIVITY; GENETIC POLYMORPHISM; HUMAN; HUMAN EXPERIMENT; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; ARYLDIALKYLPHOSPHATASE; DIOXOLANES; ESTERASES; FLUOROQUINOLONES; HUMANS; HYDROLYSIS; MALE; MICE; MICROSOMES, LIVER; MOLECULAR SEQUENCE DATA; PIPERAZINES; PRODRUGS; QUINOLONES; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SEQUENCE HOMOLOGY, AMINO ACID;

ORYCTOLAGUS CUNICULUS;

EID: 0031920093     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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