Pharmacokinetics of prulifloxacin. 1st Communication: Absorption, distribution and excretion in rats, dogs, and monkeys after a single administration

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 3, 1997, Pages 276-284

  Okuyama, Yoshio ^a   Momota, Kazuo ^a   Morino, Akira ^a  

^a NIPPON SHINYAKU CO LTD   (Japan)

Author keywords

CAS 112984 60 8; CAS 123447 62 1; NM394; NM441, pharmacokinetics; prulifloxacin, active metabolite, laboratory animals; quinolones

Indexed keywords

6 FLUORO 1 METHYL 4 OXO 7 (1 PIPERAZINYL) 4H 1,3 THIAZETO[3,2 A]QUINOLINE 3 CARBOXYLIC ACID; CARBON 14; DRUG METABOLITE; PRULIFLOXACIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DOG; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG URINE LEVEL; FEMALE; IN VITRO STUDY; INTESTINE; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MALE; MONKEY; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; WHOLE BODY AUTORADIOGRAPHY;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFECTIVE AGENTS; AUTORADIOGRAPHY; BIOTRANSFORMATION; DIOXOLANES; DOGS; FEMALE; FLUOROQUINOLONES; FOOD-DRUG INTERACTIONS; HALF-LIFE; INJECTIONS, INTRAVENOUS; INTESTINAL ABSORPTION; MACACA FASCICULARIS; MALE; PIPERAZINES; QUINOLONES; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; TISSUE DISTRIBUTION;

EID: 0031003017     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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