-
1
-
-
0030010348
-
Mutant insulin receptors in syndromes of insulin resistance
-
Shepherd M, Franklyn J, Eds. London, Balliere Tindall
-
Krook A, O'Rahilly S: Mutant insulin receptors in syndromes of insulin resistance. In Balliere's Clinical Endocrinology and Metabolism. Shepherd M, Franklyn J, Eds. London, Balliere Tindall, 1996, p. 97-122
-
(1996)
Balliere's Clinical Endocrinology and Metabolism
, pp. 97-122
-
-
Krook, A.1
O'Rahilly, S.2
-
2
-
-
0028047457
-
Molecular scanning of the insulin receptor gene in syndromes of insulin resistance
-
Krook A, Kumar S, Laing I, Boulton AJM, Wass JAH, O'Rahilly S: Molecular scanning of the insulin receptor gene in syndromes of insulin resistance. Diabetes 43:357-368, 1994
-
(1994)
Diabetes
, vol.43
, pp. 357-368
-
-
Krook, A.1
Kumar, S.2
Laing, I.3
Boulton, A.J.M.4
Wass, J.A.H.5
O'Rahilly, S.6
-
3
-
-
0028044901
-
Prevalence of mutations in the insulin receptor gene in subjects with features of the type A syndrome of insulin resistance
-
Moller DE, Cohen O, Yamaguchi Y, Assiz R, Grigorescu F, Eberle A, Morrow LA, Moses AC, Flier JS: Prevalence of mutations in the insulin receptor gene in subjects with features of the type A syndrome of insulin resistance. Diabetes 43:247-255, 1994
-
(1994)
Diabetes
, vol.43
, pp. 247-255
-
-
Moller, D.E.1
Cohen, O.2
Yamaguchi, Y.3
Assiz, R.4
Grigorescu, F.5
Eberle, A.6
Morrow, L.A.7
Moses, A.C.8
Flier, J.S.9
-
4
-
-
0025813375
-
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
-
Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PM, Cahill DA, Goldstein BJ, White MF: Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 352:73-77, 1991
-
(1991)
Nature
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.M.6
Cahill, D.A.7
Goldstein, B.J.8
White, M.F.9
-
5
-
-
0030748457
-
The insulin signalling system and the IRS proteins
-
White MF: The insulin signalling system and the IRS proteins. Diabetologia 40:S2-S17, 1997
-
(1997)
Diabetologia
, vol.40
-
-
White, M.F.1
-
6
-
-
0028023002
-
Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling
-
Tanti JF, Gremeaux T, Van Obberghen E, Le Marchand Brustel Y: Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling. J Biol Chem 269:6051-6057, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 6051-6057
-
-
Tanti, J.F.1
Gremeaux, T.2
Van Obberghen, E.3
Le Marchand Brustel, Y.4
-
7
-
-
15844389443
-
Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action
-
Mothe I, Van Obberghen E: Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action. J Biol Chem 271:11222-11227, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 11222-11227
-
-
Mothe, I.1
Van Obberghen, E.2
-
8
-
-
0027437376
-
Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1
-
Sun XJ, Crimmin DL, Myers MG, Miralpeix M, White MF: Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1. Mol Cell Biol 13:7418-7428, 1993
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7418-7428
-
-
Sun, X.J.1
Crimmin, D.L.2
Myers, M.G.3
Miralpeix, M.4
White, M.F.5
-
9
-
-
0026605216
-
Cloning and increased expression of an insulin receptor substrate-1-like gene in human hepatocellular carcinoma
-
Nishiyama M, Wands JR: Cloning and increased expression of an insulin receptor substrate-1-like gene in human hepatocellular carcinoma. Biochem Biophys Res Commun 183:280-285, 1992
-
(1992)
Biochem Biophys Res Commun
, vol.183
, pp. 280-285
-
-
Nishiyama, M.1
Wands, J.R.2
-
10
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, Neel BG, Birge RB, Fajardo JE, Chou MM, Hanafusa H, Schaffhausen B, Cantley LC: SH2 domains recognize specific phosphopeptide sequences. Cell 72:767-778, 1993
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
Shoelson, S.E.2
Chaudhuri, M.3
Gish, G.4
Pawson, T.5
Haser, W.G.6
King, F.7
Roberts, T.8
Ratnofsky, S.9
Lechleider, R.J.10
Neel, B.G.11
Birge, R.B.12
Fajardo, J.E.13
Chou, M.M.14
Hanafusa, H.15
Schaffhausen, B.16
Cantley, L.C.17
-
11
-
-
0027367546
-
Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus
-
Almind K, Bjorbaek C, Vestergaard H, Hansen T, Echwald S, Pederson O: Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus. Lancet 342:828-832, 1993
-
(1993)
Lancet
, vol.342
, pp. 828-832
-
-
Almind, K.1
Bjorbaek, C.2
Vestergaard, H.3
Hansen, T.4
Echwald, S.5
Pederson, O.6
-
12
-
-
0029893417
-
A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling
-
Almind K, Inoue G, Pederson O, Kahn CR: A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. J Clin Invest 97:2569-2575, 1996
-
(1996)
J Clin Invest
, vol.97
, pp. 2569-2575
-
-
Almind, K.1
Inoue, G.2
Pederson, O.3
Kahn, C.R.4
-
13
-
-
0030917640
-
Impact of natural IRS-1 mutations on insulin signals: Mutations of IRS-1 in the PTB domain and near SH2 protein binding sites result in impaired function at different steps of IRS-1 signaling
-
Yoshimura R, Araki E, Ura S, Todaka M, Tsuruzoe K, Furukawa N, Motoshima H, Yoshizato K, Kaneko K, Matsuda K, Kishikawa H, Shichiri M: Impact of natural IRS-1 mutations on insulin signals: mutations of IRS-1 in the PTB domain and near SH2 protein binding sites result in impaired function at different steps of IRS-1 signaling. Diabetes 46:929-936, 1997
-
(1997)
Diabetes
, vol.46
, pp. 929-936
-
-
Yoshimura, R.1
Araki, E.2
Ura, S.3
Todaka, M.4
Tsuruzoe, K.5
Furukawa, N.6
Motoshima, H.7
Yoshizato, K.8
Kaneko, K.9
Matsuda, K.10
Kishikawa, H.11
Shichiri, M.12
-
14
-
-
0028876067
-
Identification by mutation of the tyrosine residues in the insulin receptor substrate-1 affecting association with the Tyrosine phosphatase 2C and phosphatidylinositol 3-kinase
-
Rocchi S, Tartare-Deckert S, Mothe I, Van Obberghen E: Identification by mutation of the tyrosine residues in the insulin receptor substrate-1 affecting association with the Tyrosine phosphatase 2C and phosphatidylinositol 3-kinase. Endocrinology 136:5291-5297, 1995
-
(1995)
Endocrinology
, vol.136
, pp. 5291-5297
-
-
Rocchi, S.1
Tartare-Deckert, S.2
Mothe, I.3
Van Obberghen, E.4
-
15
-
-
0026594654
-
YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase
-
Shoelson SE, Chatterjee S, Chaudhuri M, White MF: YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase. Proc Natl Acad Sci 89:2027-2031, 1992
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 2027-2031
-
-
Shoelson, S.E.1
Chatterjee, S.2
Chaudhuri, M.3
White, M.F.4
-
16
-
-
0028938721
-
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
-
Songyang Z, Carraway KL, Eck MJ, Harrison SC, Feldman RA, Mohammadi M, Schlessinger J, Hubbard SR, Smith DP, Eng C, Lorenzo MJ, Ponder BAJ, Mayer BJ, Cantley LC: Catalytic specificity of protein-tyrosine kinases is critical for selective signalling. Nature 373:536-539, 1995
-
(1995)
Nature
, vol.373
, pp. 536-539
-
-
Songyang, Z.1
Carraway, K.L.2
Eck, M.J.3
Harrison, S.C.4
Feldman, R.A.5
Mohammadi, M.6
Schlessinger, J.7
Hubbard, S.R.8
Smith, D.P.9
Eng, C.10
Lorenzo, M.J.11
Ponder, B.A.J.12
Mayer, B.J.13
Cantley, L.C.14
-
17
-
-
0029927839
-
Two naturally occurring mutant insulin receptors phosphorylate insulin receptor substrate-1 (IRS-1) but fail to mediate the biological effects of insulin
-
Krook A, Moller DE, Dib K, O'Rahilly S: Two naturally occurring mutant insulin receptors phosphorylate insulin receptor substrate-1 (IRS-1) but fail to mediate the biological effects of insulin. J Biol Chem 271:7134-7140, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 7134-7140
-
-
Krook, A.1
Moller, D.E.2
Dib, K.3
O'Rahilly, S.4
-
18
-
-
14444276528
-
Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects
-
Krook A, Whitehead JP, Dobson SP, Griffiths MR, Ouwens M, Baker C, Hayward AC, Sen SK, Maassen JA, Siddle K, Tavare JM, O'Rahilly S: Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects. J Biol Chem 272:30208-30214, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 30208-30214
-
-
Krook, A.1
Whitehead, J.P.2
Dobson, S.P.3
Griffiths, M.R.4
Ouwens, M.5
Baker, C.6
Hayward, A.C.7
Sen, S.K.8
Maassen, J.A.9
Siddle, K.10
Tavare, J.M.11
O'Rahilly, S.12
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