-
1
-
-
0026579998
-
The mucosal immune system: From fundamental concepts to vaccine development
-
McGHEE J.R., MESTECKY J., DERTZBAUGH M.T., ELDRIDGE J.H., HIRASAWA M. and KIYONO H. - The mucosal immune system: from fundamental concepts to vaccine development. - Vaccine, 10, 75-88, 1992.
-
(1992)
Vaccine
, vol.10
, pp. 75-88
-
-
McGhee, J.R.1
Mestecky, J.2
Dertzbaugh, M.T.3
Eldridge, J.H.4
Hirasawa, M.5
Kiyono, H.6
-
3
-
-
0028796383
-
Mucosal immunoadjuvant activity of liposomes: Induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with an influenza subunit vaccine and coadministered liposomes
-
DE HAAN A., GEERLIGS H.J., HUCHSHORN J.P., VAN SCHARRENBURG G.J.M., PALACHE A.M. and WILSCHUT J. - Mucosal immunoadjuvant activity of liposomes: induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with an influenza subunit vaccine and coadministered liposomes. - Vaccine, 13, 155-162, 1995.
-
(1995)
Vaccine
, vol.13
, pp. 155-162
-
-
De Haan, A.1
Geerligs, H.J.2
Huchshorn, J.P.3
Van Scharrenburg, G.J.M.4
Palache, A.M.5
Wilschut, J.6
-
4
-
-
0030047688
-
Optimization of live oral Salmonella-HIV-1 vaccine vectors for the induction of HIV-specific mucosal and systemic immune responses
-
HONE D.M., WU S., POWELL R.J., PASCUAL D.W., VAN COTT J., McGHEE J.R., FOUTS T.R., TUSKAN R.G. and LEWIS G.K. - Optimization of live oral Salmonella-HIV-1 vaccine vectors for the induction of HIV-specific mucosal and systemic immune responses. - J. Biotechnol., 44, 203-207, 1996.
-
(1996)
J. Biotechnol.
, vol.44
, pp. 203-207
-
-
Hone, D.M.1
Wu, S.2
Powell, R.J.3
Pascual, D.W.4
Van Cott, J.5
McGhee, J.R.6
Fouts, T.R.7
Tuskan, R.G.8
Lewis, G.K.9
-
5
-
-
0029671022
-
Further characterization of Δaroa ΔvirG Shigella flexneri 2a strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector for delivering antigens of enterotoxigenic Escherichia coli
-
NORIEGA F.R., LOSONSKY G., WANG J.Y., FORMAL S.B. and LEVINE M.M. - Further characterization of ΔaroA ΔvirG Shigella flexneri 2a strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector for delivering antigens of enterotoxigenic Escherichia coli. - Infect. Immun., 64, 23-27, 1996.
-
(1996)
Infect. Immun.
, vol.64
, pp. 23-27
-
-
Noriega, F.R.1
Losonsky, G.2
Wang, J.Y.3
Formal, S.B.4
Levine, M.M.5
-
6
-
-
0023938398
-
Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens
-
CLEMENTS J.D., HARTZOG N.M. and LYON F.L - Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. - Vaccine, 6, 269-277, 1988.
-
(1988)
Vaccine
, vol.6
, pp. 269-277
-
-
Clements, J.D.1
Hartzog, N.M.2
Lyon, F.L.3
-
7
-
-
0022460378
-
Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens
-
LYCKE N. and HOLMGREN J. - Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. - Immunology, 59, 301-308, 1986.
-
(1986)
Immunology
, vol.59
, pp. 301-308
-
-
Lycke, N.1
Holmgren, J.2
-
8
-
-
0026458260
-
Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
-
SPANGLER B.D. - Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. - Microbiol. Rev., 56, 622-647, 1992.
-
(1992)
Microbiol. Rev.
, vol.56
, pp. 622-647
-
-
Spangler, B.D.1
-
9
-
-
0029805948
-
Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin
-
DE HAAN L, VERWEIJ W.R., FEIL I.K., LIJNEMA T.H., HOL W.G.J., AGSTERIBBE E. and WILSCHUT J. - Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin. - Infect. Immun., 64, 5413-5416, 1996.
-
(1996)
Infect. Immun.
, vol.64
, pp. 5413-5416
-
-
De Haan, L.1
Verweij, W.R.2
Feil, I.K.3
Lijnema, T.H.4
Hol, W.G.J.5
Agsteribbe, E.6
Wilschut, J.7
-
10
-
-
0028985871
-
Dissociation of Escherichia coliheat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
-
DICKINSON B.L. and CLEMENTS J.D. - Dissociation of Escherichia coliheat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. - Infect. Immun., 63, 1617-1623, 1995.
-
(1995)
Infect. Immun.
, vol.63
, pp. 1617-1623
-
-
Dickinson, B.L.1
Clements, J.D.2
-
11
-
-
0030066516
-
Induction of antigen-specific antibodies in vaginal secretions by using a non-toxic mutant of heat-labile enterotoxin as a mucosal adjuvant
-
DI TOMMASO A., SALETTI G., PIZZA M., RAPPUOLI R., DOUGAN G., ABRIGNANI S., DOUCE G. and DE MAGISTRIS MT. - Induction of antigen-specific antibodies in vaginal secretions by using a non-toxic mutant of heat-labile enterotoxin as a mucosal adjuvant. - Infect. Immun., 64, 974-979, 1996.
-
(1996)
Infect. Immun.
, vol.64
, pp. 974-979
-
-
Di Tommaso, A.1
Saletti, G.2
Pizza, M.3
Rappuoli, R.4
Dougan, G.5
Abrignani, S.6
Douce, G.7
De Magistris, M.T.8
-
12
-
-
0028918767
-
Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as non-toxic, mucosal adjuvants
-
DOUCE G., TURCOTTE C., CROPLEY I., ROBERTS M., PIZZA M., DOMENIGHINI M., RAPPUOLI R. and DOUGAN G. - Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as non-toxic, mucosal adjuvants.-Proc. Natl. Acad. Sci. USA, 92, 1644-1648, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1644-1648
-
-
Douce, G.1
Turcotte, C.2
Cropley, I.3
Roberts, M.4
Pizza, M.5
Domenighini, M.6
Rappuoli, R.7
Dougan, G.8
-
13
-
-
0029031840
-
Construction of non-toxic derivatives of cholera toxin andcharacterization of the immunological response against the A subunit
-
FONTANA M.R., MANETTI R., GIANNELLI V., MAGAGNOLI C., MARCHINI A., OLIVIERI R., DOMENIGHINI M., RAPPUOLI R. and PIZZA M. - Construction of non-toxic derivatives of cholera toxin andcharacterization of the immunological response against the A subunit. - Infect. Immun., 63, 2356-2360, 1995.
-
(1995)
Infect. Immun.
, vol.63
, pp. 2356-2360
-
-
Fontana, M.R.1
Manetti, R.2
Giannelli, V.3
Magagnoli, C.4
Marchini, A.5
Olivieri, R.6
Domenighini, M.7
Rappuoli, R.8
Pizza, M.9
-
14
-
-
0027992673
-
A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit
-
PIZZA M., FONTANA M.R., GIULIANI M.M., DOMENIGHINI M., MAGAGNOLI C., GIANNELLI V., NUCCI D., HOL W.G.J., MANETTI R. and RAPPUOLI R. - A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit. - J. Exp. Med., 180, 2147-2153, 1994.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2147-2153
-
-
Pizza, M.1
Fontana, M.R.2
Giuliani, M.M.3
Domenighini, M.4
Magagnoli, C.5
Giannelli, V.6
Nucci, D.7
Hol, W.G.J.8
Manetti, R.9
Rappuoli, R.10
-
15
-
-
0026699224
-
The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity
-
LYCKE N., TSUJI T. and HOLMGREN J. - The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity. - Eur. J. Immunol., 22, 2277-2281, 1992.
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 2277-2281
-
-
Lycke, N.1
Tsuji, T.2
Holmgren, J.3
-
16
-
-
0027411361
-
Intranasal immunization against herpes simplex virus infection by using a recombinant glycoprotein D fused with immunomodulating proteins, the B subunit of Escherichia coli heat-labile enterotoxin and interleukin-2
-
HAZAMA M., MAYUMI-AONO A., MIYAZAKI, T., HINUMA S. and FUJISAWA Y. - Intranasal immunization against herpes simplex virus infection by using a recombinant glycoprotein D fused with immunomodulating proteins, the B subunit of Escherichia coli heat-labile enterotoxin and interleukin-2. -Immunology, 78, 643-649, 1993.
-
(1993)
Immunology
, vol.78
, pp. 643-649
-
-
Hazama, M.1
Mayumi-Aono, A.2
Miyazaki, T.3
Hinuma, S.4
Fujisawa, Y.5
-
17
-
-
0031027336
-
Protease susceptibility and toxicity of heat-labile enterotoxins with a mutation in the active site or in the protease-sensitive loop
-
GIANNELLI V., FONTANA M.R., GIULIANI M.M., GUANGCAI D., RAPPUOLI R. and PIZZA M. - Protease susceptibility and toxicity of heat-labile enterotoxins with a mutation in the active site or in the protease-sensitive loop. - Infect. Immun., 65, 331-334, 1997.
-
(1997)
Infect. Immun.
, vol.65
, pp. 331-334
-
-
Giannelli, V.1
Fontana, M.R.2
Giuliani, M.M.3
Guangcai, D.4
Rappuoli, R.5
Pizza, M.6
-
18
-
-
0028296259
-
Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose
-
UESAKA Y., OTSUKA Y., LIN Z., YAMASAKI S., YAMAOKA J., KURAZONO H. and TAKEDA Y. - Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose. - Microb. Pathog., 16, 71-76, 1994.
-
(1994)
Microb. Pathog.
, vol.16
, pp. 71-76
-
-
Uesaka, Y.1
Otsuka, Y.2
Linz, Z.3
Yamasaki, S.4
Yamaoka, J.5
Kurazono, H.6
Takeda, Y.7
-
19
-
-
0029897005
-
Protein engineering studies of A-chain loop 47-56 of E. coli heat-labile enterotoxin point to a prominent role of this loop for cytotoxicity
-
FEIL I.K., REDDY R., DE HAAN L, MERRITT E.A., VAN DEN AKKER F., STORM D.R. and HOL W.G.J. - Protein engineering studies of A-chain loop 47-56 of E. coli heat-labile enterotoxin point to a prominent role of this loop for cytotoxicity. - Mol. Microbiol., 20, 823-832, 1996.
-
(1996)
Mol. Microbiol.
, vol.20
, pp. 823-832
-
-
Feil, I.K.1
Reddy, R.2
De Haan, L.3
Merritt, E.A.4
Van Den Akker, F.5
Storm, D.R.6
Hol, W.G.J.7
-
20
-
-
0029865302
-
Mucosal immunogenicity of the Escherichia coli heat-labile enterotoxin: Role of the A subunit
-
DE HAAN L., VERWEIJ W.R., HOLTROP M., AGSTERIBBE E. and WILSCHUT J. - Mucosal immunogenicity of the Escherichia coli heat-labile enterotoxin: role of the A subunit. - Vaccine, 14, 620-626, 1996.
-
(1996)
Vaccine
, vol.14
, pp. 620-626
-
-
De Haan, L.1
Verweij, W.R.2
Holtrop, M.3
Agsteribbe, E.4
Wilschut, J.5
-
21
-
-
0028028168
-
Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcuspneumoniae
-
ALEXANDER J.E., LOCK R.A., PEETERS C.C.A.M., POOLMAN J.T., ANDREW P.W., MITCHELL T.J., HANSMAN D. and PATON J.C. - Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcuspneumoniae. - Infect. Immun., 62, 5683-5688, 1994.
-
(1994)
Infect. Immun.
, vol.62
, pp. 5683-5688
-
-
Alexander, J.E.1
Lock, R.A.2
Peeters, C.C.A.M.3
Poolman, J.T.4
Andrew, P.W.5
Mitchell, T.J.6
Hansman, D.7
Paton, J.C.8
-
22
-
-
0023767597
-
Protection against influenza virus infection by a vaccine inocculated with cholera toxin B subunit
-
TAMURA S.I., SAMEGAI Y., KURATA H., NAGAMINE T., AIZAWA C. and KURATA T. - Protection against influenza virus infection by a vaccine inocculated with cholera toxin B subunit. -Vaccine, 6, 409-415, 1988.
-
(1988)
Vaccine
, vol.6
, pp. 409-415
-
-
Tamura, S.I.1
Samegai, Y.2
Kurata, H.3
Nagamine, T.4
Aizawa, C.5
Kurata, T.6
-
23
-
-
0027396382
-
Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit
-
WU W.Y. and RUSSELL M.W. - Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit. - Infect. Immun., 61, 314-322, 1993.
-
(1993)
Infect. Immun.
, vol.61
, pp. 314-322
-
-
Wu, W.Y.1
Russell, M.W.2
-
24
-
-
0024565465
-
Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues
-
CZERKINSKY C., RUSSELL M.W., LYCKE N., LINDBLAD M., and HOLMGREN J. - Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues. - Infect. Immun., 57, 1072-1077, 1989.
-
(1989)
Infect. Immun.
, vol.57
, pp. 1072-1077
-
-
Czerkinsky, C.1
Russell, M.W.2
Lycke, N.3
Lindblad, M.4
Holmgren, J.5
-
25
-
-
0028220582
-
Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine
-
TAMURA S.-I, YAMANAKA A., SHIMOHARA M., TOMITA T., KOMASE K., TSUDA T., SUZUKI Y., NAGAMINE T., KAWAHARA K., DANBARA H., AIZAWA C., OYA A. and KURATA T. - Synergistic action of cholera toxin B subunit (and Escherichia coli heat-labile toxin B subunit) and a trace amount of cholera whole toxin as an adjuvant for nasal influenza vaccine.-Vaccine, 12,419-426, 1994.
-
(1994)
Vaccine
, vol.12
, pp. 419-426
-
-
Tamura, S.-I.1
Yamanaka, A.2
Shimohara, M.3
Tomita, T.4
Komase, K.5
Tsuda, T.6
Suzuki, Y.7
Nagamine, T.8
Kawahara, K.9
Danbara, H.10
Aizawa, C.11
Oya, A.12
Kurata, T.13
-
26
-
-
0027486404
-
Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems
-
HOLMGREN J., LYCKE N. and CZERKINSKY C. - Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems. - Vaccine, 11, 1179-1184, 1993.
-
(1993)
Vaccine
, vol.11
, pp. 1179-1184
-
-
Holmgren, J.1
Lycke, N.2
Czerkinsky, C.3
-
27
-
-
0028150631
-
Protective efficacy of oral whole cell/recombinant-B-subunit cholera vaccine in Peruvian military recruits
-
SANCHEZ J.L., VASQUEZ B., BEGUE R.E. et al. - Protective efficacy of oral whole cell/recombinant-B-subunit cholera vaccine in Peruvian military recruits. - Lancet, 344, 1273-1276, 1994.
-
(1994)
Lancet
, vol.344
, pp. 1273-1276
-
-
Sanchez, J.L.1
Vasquez, B.2
Begue, R.E.3
-
29
-
-
0030902280
-
Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity
-
YAMAMOTO S., TAKEDA Y., YAMAMOTO M., KURAZONO H., IMAOKA K., YAMAMOTO M., FUJIHASHI K., NODA M., KIYONO H., and McGHEE J.R. - Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity. - J. Exp. Med., 185, 1203-1210, 1997.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1203-1210
-
-
Yamamoto, S.1
Takeda, Y.2
Yamamoto, M.3
Kurazono, H.4
Imaoka, K.5
Yamamoto, M.6
Fujihashi, K.7
Noda, M.8
Kiyono, H.9
McGhee, J.R.10
-
30
-
-
0029493562
-
The mucosal adjuvant activities of ADP-ribosylating bacterial enterotoxins
-
SNIDER D.P. - The mucosal adjuvant activities of ADP-ribosylating bacterial enterotoxins. - Crit. Rev. Immunol., 15, 317-348, 1996.
-
(1996)
Crit. Rev. Immunol.
, vol.15
, pp. 317-348
-
-
Snider, D.P.1
|