Artesunate and mefloquine in the treatment of uncomplicated multidrug-resistant hyperparasitaemic falciparum malaria

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 92, Issue 2, 1998, Pages 207-211

  Price, Ric ^a,b,c,e   Luxemburger, Christine ^a,b,e   Van Vugt, Michele ^a,b,d   Nosten, François ^a,b,e   Kham, Am ^a   Simpson, Julie ^b,e   Looareesuwan, Sornchai ^b   Chongsuphajaisiddhi, Tan ^b   White, Nicholas J ^b,e  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Artesunate; Chemotherapy; Malaria; Mefloquine; Plasmodium falciparum

Indexed keywords

ANTIMALARIAL AGENT; ARTESUNATE; MEFLOQUINE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG TOLERABILITY; ENDEMIC DISEASE; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MULTIDRUG RESISTANCE; ORAL DRUG ADMINISTRATION; PARASITEMIA; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD;

ARTESUNATE; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0031917497     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(98)90750-7     Document Type: Article

References (13)

1. Fontanet, A. L. & Walker, A. M. (1993). Predictors of treatment failure in multiple drug-resistant falciparum malaria: results from a 42-day follow-up of 224 patients in eastern Thailand. American Journal of Tropical Medicine and Hygiene, 49, 465-472.
2. Hien, T. T. & White, N. J. (1993). Qinghaosu. Lancet, 341, 603-608.
3. Li, G.-Q., Guo, X.-B., Fu, L.-C., Jian, H.-X & Wang, X.-H. (1994). Clinical trials of artemisinin and its derivatives in the treatment of malaria in China. Transactions of the Royal Society of Tropical Medicine and Hygiene, 88, supplement 1, S1/5-S1/6.
4. Looareesuwan, S., Kyle, D., Viravan, S., Vanijanonta, S.,Wilairatana, P., Charoenlarp, P., Canfield, C. & Webster, K. (1994). Treatment of patients with recrudescent falciparum malaria with sequential combinations of artesunate and mefloquine. American Journal of Tropical Medicine and Hygiene, 47, 794-799.
5. Luxemburger, C., Nosten, F., Shotar, Raimond, D., Chongsuphajaisiddhi,T. & White, N. J. (1995). Oral artesunate in the treatment of uncomplicated hyperparasitemic falciparum malaria. American Journal of Tropical Medicine and Hygiene, 53, 522-525.
6. Luxemburger, C., Kyaw Lay Thwai, White, N. J., Webster, H. K., Kyle, D. E., Maelankirri, L., Chongsuphajaisiddhi, T. & Nosten, F. (1996). The epidemiology of malaria in a Karen population on the western border of Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene, 90, 105-111.
7. Luxemburger, C., Ricci, F., Nosten, F., Raimond, D., Saw Bathet & White, N. J. (1997). The epidemiology of severe malaria in an area of low transmission in Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene, 91, 256-262.
8. Mai, N.T. H., Day, N. P. J., Chuong, L. V., Waller, D., Phu, N. H., Bethell, D., Hien, & White, N. J. (1996). Post-malaria neurological syndrome. Lancet, 348, 917-921.
9. Nosten, F., Luxemburger, C., ter Kuile, F. O., Woodrow, C., Pa Eh, J., Chongsuphajaisiddhi, T. & White, N. J. (1994). Treatment of multi-drug resistant Plasmodium falciparum malaria with a 3 day artesunate-mefloquine combination. Journal of Infectious Diseases, 170, 971-977.
10. Nosten, F., Luxemburger, C., Kyle, D. E., Ballou, W. R., Wittes, R., Eh Wah, Chongsuphajaisiddhi, T., Gordon, D. M.,White, N. J., Sadoff, J. & Heppner, D. G. (1996). Randomised double-blind placebo controlled trial of SPf66 malaria vaccine in children in northwestern Thailand. Lancet, 348, 701-707.
11. Price, R. N., Nosten, F., Luxemburger, C., van Vugt, M., Phaipun, L., Chongsuphajaisiddhi,T. & White, N. J. (1997). Artesunate/mefloquine treatment of multi-drug resistant falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 91, 574-577.
12. Ter Kuile, F. O., Luxemburger, C., Nosten, F., Kyaw Lay Thwai, Chongsuphajaisiddhi, T. & White, N. J. (1995). Predictors of mefloquine treatment failure: a prospective study in 1590 patients with uncomplicated falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 89, 660-664.
13. White, N. J. (1997). Assessment of the pharmacodynamic properties of antimalarial drugs in-vivo. Antimicrobial Agents and Chemotherapy, 41, 1413-1422.