Are two antidepressant mechanisms better than one?

Journal of Clinical Psychiatry

Volumn 58, Issue 8, 1997, Pages 339-340

  Stahl, Stephen M ^a  

^a BRAINSTORMS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOMIPRAMINE; MIRTAZAPINE; MONOAMINE OXIDASE INHIBITOR; NEFAZODONE; NORADRENALIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE;

ANXIETY; DEPRESSION; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG TOLERABILITY; HUMAN; NAUSEA; PRIORITY JOURNAL; SEXUAL DYSFUNCTION; SHORT SURVEY;

EID: 0030776757     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.v58n0801     Document Type: Short Survey

References (10)

1. Stahl SM. Essential Psychopharmacology. New York, NY: Cambridge University Press; 1996
2. de Boer T. The effects of mirtazapine on central noradrenergic and serotonergic neurotransmission. Int Clin Psychopharmacol 1995;10(suppl 4):19-23
3. Stimml GL, Dopheide JA, Stahl SM. Mirtazapine: an antidepressant with noradrenergic and specific serotonergic effects. Pharmacotherapy 1997;17:10-21
4. Pedersen L, Klysner R. Antagonism of selective serotonin reuptake inhibitor-induced nausea by mirtazapine. Int Clin Psychopharmacol 1997;12:59-60
5. Danish University Antidepressant Group. Citalopram: clinical effect profile in comparison with clomipramine: a controlled multicenter study. Psychopharmacology (Berl) 1986;90: 131-138
6. Danish University Antidepressant Group. Paroxetine: a selective serotonin reuptake inhibitor showing better tolerance but weaker antidepressant effect than clomipramine in a controlled multicenter study. J Affect Disord 1990; 18:289-299
7. Clerc GE, Ruimy P, Verdeau-Pailles J, on behalf of the Venlafaxine French Inpatient Study Group. A double-blind comparison of venlafaxine and fluoxetine in patients hospitalized for minor depression and melancholia. Int Clin Psychopharmacol 1994;9:139-143
8. Wheatley D, Kremer C. A randomized, double-blind comparison of mirtazapine and fluoxetine in patients with major depression. In: New Research Program and Abstracts of the American Psychiatric Association; May 17-22, 1997; San Diego, Calif
9. Shader RI, Fogelman SM, Greenblatt DJ. Newer antidepressants: hypotheses and evidence [editorial]. J Clin Psychopharmacol 1997;17:1-3
10. Schatzberg AF. Treatment of severe depression with the selective serotonin reuptake inhibitors. Depression and Anxiety 1996;4:182-189