메뉴 건너뛰기




Volumn 70, Issue 2, 1998, Pages 699-707

Inflammatory signals induce neurotrophin expression in human microglial cells

Author keywords

Alzheimer's disease; Complement factors; Cytokines; Nerve growth factor

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; COMPLEMENT COMPONENT C3A; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN 4; PYRROLIDINE DITHIOCARBAMATE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0031913982     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70020699.x     Document Type: Article
Times cited : (254)

References (65)
  • 1
    • 0026530256 scopus 로고
    • Basic FGF in astroglial, microglial, and neuronal cultures: Characterization of binding sites and modulation of release by lymphokines and trophic factors
    • Araujo D. M. and Cotman C. W. (1992) Basic FGF in astroglial, microglial, and neuronal cultures: characterization of binding sites and modulation of release by lymphokines and trophic factors. J. Neurosci. 12, 1668-1678.
    • (1992) J. Neurosci. , vol.12 , pp. 1668-1678
    • Araujo, D.M.1    Cotman, C.W.2
  • 2
    • 0030271387 scopus 로고    scopus 로고
    • NF-κB: Ten years after
    • Baeuerle P. A. and Baltimore D. (1996) NF-κB: ten years after. Cell 87, 13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 4
    • 0029328620 scopus 로고
    • Inflammatory reaction in experimental autoimmune encephalomyelitis (EAE) is accompanied by a microglial expression of the βA4-amyloid precursor protein (APP)
    • Banati R. B., Gehrmann J., Lannes-Vieira J., Wekerle H., and Kreutzberg G. W. (1995) Inflammatory reaction in experimental autoimmune encephalomyelitis (EAE) is accompanied by a microglial expression of the βA4-amyloid precursor protein (APP). Glia 14, 209-215.
    • (1995) Glia , vol.14 , pp. 209-215
    • Banati, R.B.1    Gehrmann, J.2    Lannes-Vieira, J.3    Wekerle, H.4    Kreutzberg, G.W.5
  • 5
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes P. J. and Karin M. (1997) Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336, 1066-1071.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 7
    • 0029998346 scopus 로고    scopus 로고
    • The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide
    • Boland K., Behrens M., Choi D., Manias K., and Perlmutter D. H. (1996) The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide. J. Biol. Chem. 271, 18032-18044.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18032-18044
    • Boland, K.1    Behrens, M.2    Choi, D.3    Manias, K.4    Perlmutter, D.H.5
  • 9
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 10
    • 0026713423 scopus 로고
    • β-Amyloid neurotoxicity: A discussion of in vitro findings
    • Cotman C. W., Pike C. J., and Copani A. (1992) β-Amyloid neurotoxicity: a discussion of in vitro findings. Neurobiol. Aging 13, 587-590.
    • (1992) Neurobiol. Aging , vol.13 , pp. 587-590
    • Cotman, C.W.1    Pike, C.J.2    Copani, A.3
  • 11
    • 0028260210 scopus 로고
    • Cellular forms and functions of brain microglia
    • Davies E. J., Foster T. D., and Thomas W. E. (1994) Cellular forms and functions of brain microglia. Brain Res. Bull. 34, 73-78.
    • (1994) Brain Res. Bull. , vol.34 , pp. 73-78
    • Davies, E.J.1    Foster, T.D.2    Thomas, W.E.3
  • 12
    • 0028946146 scopus 로고
    • Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures
    • Del Bo R., Angeretti N., Lucca E., De Simoni M. G., and Forloni G. (1995) Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures. Neurosci. Lett. 188, 70-74.
    • (1995) Neurosci. Lett. , vol.188 , pp. 70-74
    • Del Bo, R.1    Angeretti, N.2    Lucca, E.3    De Simoni, M.G.4    Forloni, G.5
  • 13
    • 0027354484 scopus 로고
    • Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
    • Dickson D. W., Lee S. C., Mattiace L. A., Yen S. H., and Brosnan C. (1993) Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 7, 75-83.
    • (1993) Glia , vol.7 , pp. 75-83
    • Dickson, D.W.1    Lee, S.C.2    Mattiace, L.A.3    Yen, S.H.4    Brosnan, C.5
  • 14
    • 0027429536 scopus 로고
    • Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase trk in activated CD4-positive T-cell clones
    • Ehrhard P. B., Erb P., Graumann U., and Otten U. (1993a) Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase trk in activated CD4-positive T-cell clones. Proc. Natl. Acad. Sci. USA 90, 10984-10988.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10984-10988
    • Ehrhard, P.B.1    Erb, P.2    Graumann, U.3    Otten, U.4
  • 15
  • 17
    • 0029972857 scopus 로고    scopus 로고
    • Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function
    • Elkabes S., DiCicco-Bloom E. M., and Black I. B. (1996) Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function. J. Neurosci. 16, 2508-2521.
    • (1996) J. Neurosci. , vol.16 , pp. 2508-2521
    • Elkabes, S.1    DiCicco-Bloom, E.M.2    Black, I.B.3
  • 19
    • 0024997223 scopus 로고
    • Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor release from cultured astrocytes
    • Gadient R. A., Cron C., and Otten U. (1990) Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor release from cultured astrocytes. Neurosci. Lett. 117, 335-340.
    • (1990) Neurosci. Lett. , vol.117 , pp. 335-340
    • Gadient, R.A.1    Cron, C.2    Otten, U.3
  • 20
    • 0025917576 scopus 로고
    • Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus
    • Gall C., Murray K., and Isackson P. J. (1991) Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus. Mol. Brain Res. 9, 113-123.
    • (1991) Mol. Brain Res. , vol.9 , pp. 113-123
    • Gall, C.1    Murray, K.2    Isackson, P.J.3
  • 21
    • 0001352432 scopus 로고
    • Microglia and disease of the nervous system
    • Giulian D. (1992) Microglia and disease of the nervous system. Curr. Neurol. 12, 23-54.
    • (1992) Curr. Neurol. , vol.12 , pp. 23-54
    • Giulian, D.1
  • 22
    • 0025609978 scopus 로고
    • Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1
    • Giulian D., Vaca K., and Noonan C. A. (1990) Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 250, 1593-1596.
    • (1990) Science , vol.250 , pp. 1593-1596
    • Giulian, D.1    Vaca, K.2    Noonan, C.A.3
  • 26
    • 0027468515 scopus 로고
    • Synthetic Alzheimer amyloid β/A4 peptides enhance production of complement C3 component by cultured microglial cells
    • Haga S., Ikeda K., Sato M., and Ishii T. (1993) Synthetic Alzheimer amyloid β/A4 peptides enhance production of complement C3 component by cultured microglial cells. Brain Res. 601, 88-94.
    • (1993) Brain Res. , vol.601 , pp. 88-94
    • Haga, S.1    Ikeda, K.2    Sato, M.3    Ishii, T.4
  • 27
    • 0025077238 scopus 로고
    • Quantitative PCR: The determination of template copy numbers by temperature gradient gel electrophoresis (TGGE)
    • Henco K. and Heibey M. (1990) Quantitative PCR: the determination of template copy numbers by temperature gradient gel electrophoresis (TGGE). Nucleic Acids Res. 18, 6733-6734.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 6733-6734
    • Henco, K.1    Heibey, M.2
  • 28
    • 0027176524 scopus 로고
    • Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B
    • Henkel T., Machleidt T., Alkalay I., Krönke M., Ben-Neriah Y., and Baeuerle P. A. (1993) Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B. Nature 365, 182-185.
    • (1993) Nature , vol.365 , pp. 182-185
    • Henkel, T.1    Machleidt, T.2    Alkalay, I.3    Krönke, M.4    Ben-Neriah, Y.5    Baeuerle, P.A.6
  • 29
    • 0029115575 scopus 로고
    • Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen
    • Janabi N., Peudenier S., Héron B., Heng Ng K., and Tardieu M. (1995) Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen. Neurosci. Lett. 195, 105-108.
    • (1995) Neurosci. Lett. , vol.195 , pp. 105-108
    • Janabi, N.1    Peudenier, S.2    Héron, B.3    Heng Ng, K.4    Tardieu, M.5
  • 30
    • 0030983079 scopus 로고    scopus 로고
    • Transcription factor NF-κB is activated in primary neurons by amyloid peptides and in neurons surrounding early plaques from patients with Alzheimer disease
    • Kaltschmidt B., Uherek M., Volk B., Baeuerle P. A., and Kaltschmidt C. (1997) Transcription factor NF-κB is activated in primary neurons by amyloid peptides and in neurons surrounding early plaques from patients with Alzheimer disease. Proc. Natl. Acad. Sci. USA 94, 2642-2647.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2642-2647
    • Kaltschmidt, B.1    Uherek, M.2    Volk, B.3    Baeuerle, P.A.4    Kaltschmidt, C.5
  • 32
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg G. W. (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19, 312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 33
    • 0024545848 scopus 로고
    • Neuronglia relationship during regeneration of motoneurons
    • Kreutzberg G. W., Graeber M. B., and Streit W. (1986) Neuronglia relationship during regeneration of motoneurons. Metab. Brain Dis. 4, 81-85.
    • (1986) Metab. Brain Dis. , vol.4 , pp. 81-85
    • Kreutzberg, G.W.1    Graeber, M.B.2    Streit, W.3
  • 34
    • 0023236055 scopus 로고
    • The nerve growth factor 35 years later
    • Levi-Montalcini R. (1987) The nerve growth factor 35 years later. Science 237, 1154-1162.
    • (1987) Science , vol.237 , pp. 1154-1162
    • Levi-Montalcini, R.1
  • 35
    • 0023000607 scopus 로고
    • Nerve growth factor as a paradigm for polypeptide growth factors
    • Levi-Montalcini R. and Calissano P. (1986) Nerve growth factor as a paradigm for polypeptide growth factors. Trends Neurosci. 9, 473-477.
    • (1986) Trends Neurosci. , vol.9 , pp. 473-477
    • Levi-Montalcini, R.1    Calissano, P.2
  • 36
    • 0028065290 scopus 로고
    • Brain macrophages: Neurotoxic or neurotrophic effector cells?
    • Mallat M. and Chamak B. (1994) Brain macrophages: neurotoxic or neurotrophic effector cells? J. Leukocyte Biol. 56, 416-422.
    • (1994) J. Leukocyte Biol. , vol.56 , pp. 416-422
    • Mallat, M.1    Chamak, B.2
  • 37
    • 0024514228 scopus 로고
    • Lipopolysaccharide-stimulated rat brain macrophages release NGF in vitro
    • Mallat M., Houlgatte R., Brachet P., and Prochiantz A. (1989) Lipopolysaccharide-stimulated rat brain macrophages release NGF in vitro. Dev. Biol. 133, 309-311.
    • (1989) Dev. Biol. , vol.133 , pp. 309-311
    • Mallat, M.1    Houlgatte, R.2    Brachet, P.3    Prochiantz, A.4
  • 38
    • 0025786684 scopus 로고
    • Glial changes following an excitotoxic lesion in the CNS. I. Microglia/macrophages
    • Marty S., Dusart I., and Peschanski M. (1991) Glial changes following an excitotoxic lesion in the CNS. I. Microglia/macrophages. Neuroscience 45, 529-539.
    • (1991) Neuroscience , vol.45 , pp. 529-539
    • Marty, S.1    Dusart, I.2    Peschanski, M.3
  • 39
    • 0030961544 scopus 로고    scopus 로고
    • Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia
    • McDonald D. R., Brunden K. R., and Landreth G. E. (1997) Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia. J. Neurosci. 17, 2284-2294.
    • (1997) J. Neurosci. , vol.17 , pp. 2284-2294
    • McDonald, D.R.1    Brunden, K.R.2    Landreth, G.E.3
  • 40
    • 0029610011 scopus 로고
    • The inflammatory response system of the brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer P. L. and McGeer E. G. (1995) The inflammatory response system of the brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res. Rev. 21, 195-218.
    • (1995) Brain Res. Rev. , vol.21 , pp. 195-218
    • McGeer, P.L.1    McGeer, E.G.2
  • 41
    • 0023633015 scopus 로고
    • Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR
    • McGeer P. L., Itagaki S., Tago H., and McGeer E. G. (1987) Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR. Neurosci. Lett. 79, 195-200.
    • (1987) Neurosci. Lett. , vol.79 , pp. 195-200
    • McGeer, P.L.1    Itagaki, S.2    Tago, H.3    McGeer, E.G.4
  • 44
    • 0030210955 scopus 로고    scopus 로고
    • β-Amyloid (25-35) peptide and IFN-γ synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells
    • Meda L., Bernasconi S., Bonaiuto C., Sozzani S., Zhou D., Otvos L. Jr., Mantovani A., Rossi F., and Cassatella A. M. (1996) β-Amyloid (25-35) peptide and IFN-γ synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells. J. Immunol. 155, 1213-1218.
    • (1996) J. Immunol. , vol.155 , pp. 1213-1218
    • Meda, L.1    Bernasconi, S.2    Bonaiuto, C.3    Sozzani, S.4    Zhou, D.5    Otvos Jr., L.6    Mantovani, A.7    Rossi, F.8    Cassatella, A.M.9
  • 45
    • 0031172065 scopus 로고    scopus 로고
    • NF-κB: A crucial transcription factor for glial and neuronal cell function
    • O'Neill L. A. J. and Kaltschmidt K. (1997) NF-κB: a crucial transcription factor for glial and neuronal cell function. Trends Neurosci. 20, 252-258.
    • (1997) Trends Neurosci. , vol.20 , pp. 252-258
    • O'Neill, L.A.J.1    Kaltschmidt, K.2
  • 46
    • 0029013842 scopus 로고
    • Neurotrophins and cytokines - Intermediaries between the immune and nervous systems
    • Otten U. and Gadient R. A. (1995) Neurotrophins and cytokines - intermediaries between the immune and nervous systems. Int. J. Dev. Neurosci. 13, 147-151.
    • (1995) Int. J. Dev. Neurosci. , vol.13 , pp. 147-151
    • Otten, U.1    Gadient, R.A.2
  • 47
    • 0000577580 scopus 로고
    • Synthesis and release of nerve growth factor by rat macrophages
    • Otten U., Weskamp G., Hardung M., and Meyer D. K. (1987) Synthesis and release of nerve growth factor by rat macrophages. Soc. Neurosci. Abstr. 13, 184.
    • (1987) Soc. Neurosci. Abstr. , vol.13 , pp. 184
    • Otten, U.1    Weskamp, G.2    Hardung, M.3    Meyer, D.K.4
  • 48
    • 0028588573 scopus 로고
    • Neurotrophins: Signals between the nervous and immune systems
    • Otten U., Scully J. L., Ehrhard P. B., and Gadient R. A. (1994) Neurotrophins: signals between the nervous and immune systems. Prog. Brain Res. 103, 293-305.
    • (1994) Prog. Brain Res. , vol.103 , pp. 293-305
    • Otten, U.1    Scully, J.L.2    Ehrhard, P.B.3    Gadient, R.A.4
  • 49
    • 0030248270 scopus 로고    scopus 로고
    • Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via a scavenger receptor
    • Paresce D. M., Ghosh R. N., and Maxfield F. R. (1996) Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via a scavenger receptor. Neuron 17, 553-565.
    • (1996) Neuron , vol.17 , pp. 553-565
    • Paresce, D.M.1    Ghosh, R.N.2    Maxfield, F.R.3
  • 50
    • 0028981219 scopus 로고
    • Structure-activity analyses of β-amyloid peptides: Contributions of the β25-35 region to aggregation and neurotoxicity
    • Pike C. J., Walencewicz-Wassermann A. J., Kosmoski J., Cribbs D. H., Glabe C. G., and Cotman C. W. (1995) Structure-activity analyses of β-amyloid peptides: contributions of the β25-35 region to aggregation and neurotoxicity. J. Neurochem. 64, 253-265.
    • (1995) J. Neurochem. , vol.64 , pp. 253-265
    • Pike, C.J.1    Walencewicz-Wassermann, A.J.2    Kosmoski, J.3    Cribbs, D.H.4    Glabe, C.G.5    Cotman, C.W.6
  • 51
    • 0026507049 scopus 로고
    • Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification
    • Price T., Aitken J., and Simpson E. R. (1992) Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification. J. Clin. Endocrinol. Metab. 74, 879-883.
    • (1992) J. Clin. Endocrinol. Metab. , vol.74 , pp. 879-883
    • Price, T.1    Aitken, J.2    Simpson, E.R.3
  • 52
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor γB activation in intact cells
    • Schreck R., Meier B., Männel D. N., Droge W., and Baeuerle P. A. (1992) Dithiocarbamates as potent inhibitors of nuclear factor γB activation in intact cells. J. Exp. Med. 175, 1181-1194.
    • (1992) J. Exp. Med. , vol.175 , pp. 1181-1194
    • Schreck, R.1    Meier, B.2    Männel, D.N.3    Droge, W.4    Baeuerle, P.A.5
  • 53
    • 0027207091 scopus 로고
    • Glucocorticoid modulation of neurotrophin expression in immortalized mouse hippocampal neurons
    • Scully J. L. and Otten U. (1993) Glucocorticoid modulation of neurotrophin expression in immortalized mouse hippocampal neurons. Neurosci. Lett. 155, 11-14.
    • (1993) Neurosci. Lett. , vol.155 , pp. 11-14
    • Scully, J.L.1    Otten, U.2
  • 54
    • 0026099861 scopus 로고
    • Production of basic fibroblast growth factor in cultured brain microglia
    • Shimojo M., Nakajima K., Takei N., Hamanoue M., and Kohsaka S. (1991) Production of basic fibroblast growth factor in cultured brain microglia. Neurosci. Lett. 123, 229-231.
    • (1991) Neurosci. Lett. , vol.123 , pp. 229-231
    • Shimojo, M.1    Nakajima, K.2    Takei, N.3    Hamanoue, M.4    Kohsaka, S.5
  • 55
    • 0028354917 scopus 로고
    • Increased levels of nerve growth factor (NGF) protein and mRNA and reactive gliosis following kainic acid injection into the rat striatum
    • Strauss S., Otten U., Joggerst B., Plüss K., and Volk B. (1994) Increased levels of nerve growth factor (NGF) protein and mRNA and reactive gliosis following kainic acid injection into the rat striatum. Neurosci. Lett. 168, 193-196.
    • (1994) Neurosci. Lett. , vol.168 , pp. 193-196
    • Strauss, S.1    Otten, U.2    Joggerst, B.3    Plüss, K.4    Volk, B.5
  • 56
    • 0027168447 scopus 로고
    • NF-kappa B controls expression of inhibitor I kappa B alpha: Evidence for an inducible autoregulatory pathway
    • Sun S. C., Ganchi P. A., Ballard D. W., and Greene W. C. (1993) NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. Science 259, 1912-1915.
    • (1993) Science , vol.259 , pp. 1912-1915
    • Sun, S.C.1    Ganchi, P.A.2    Ballard, D.W.3    Greene, W.C.4
  • 57
    • 0027464886 scopus 로고
    • Treatment of rat retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro
    • Thanos S., Mey J., and Wild M. (1993) Treatment of rat retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro. J. Neurosci. 13, 455-466.
    • (1993) J. Neurosci. , vol.13 , pp. 455-466
    • Thanos, S.1    Mey, J.2    Wild, M.3
  • 58
    • 0019071287 scopus 로고
    • Physiology of nerve growth factor
    • Thoenen H. and Barde Y.-A. (1980) Physiology of nerve growth factor. Trends Neurosci. 60, 1284-1335.
    • (1980) Trends Neurosci. , vol.60 , pp. 1284-1335
    • Thoenen, H.1    Barde, Y.-A.2
  • 59
    • 0026708978 scopus 로고
    • Brain macrophages: Evaluation of microglia and their functions
    • Thomas W. E. (1992) Brain macrophages: evaluation of microglia and their functions. Brain Res. Rev. 17, 61-74.
    • (1992) Brain Res. Rev. , vol.17 , pp. 61-74
    • Thomas, W.E.1
  • 61
    • 0027531855 scopus 로고
    • Construction of recombinant RNA templates for use as internal standards in quantitative RT-PCR
    • Vanden Heuval J., Tyson F., and Bell D. (1993) Construction of recombinant RNA templates for use as internal standards in quantitative RT-PCR. Biotechniques 14, 395-398.
    • (1993) Biotechniques , vol.14 , pp. 395-398
    • Vanden Heuval, J.1    Tyson, F.2    Bell, D.3
  • 62
    • 0028923898 scopus 로고
    • Complement and cytokine gene expression in cultured microglia derived from postmortem human brains
    • Walker D. G., Kim S. U., and McGeer P. L. (1995) Complement and cytokine gene expression in cultured microglia derived from postmortem human brains. J. Neurosci. Res. 40, 478-493.
    • (1995) J. Neurosci. Res. , vol.40 , pp. 478-493
    • Walker, D.G.1    Kim, S.U.2    McGeer, P.L.3
  • 63
    • 0023219442 scopus 로고
    • An enzyme-linked immunoassay for nerve growth factor (NGF): A tool for studying regulatory mechanisms involved in NGF production in brain and peripheral tissues
    • Weskamp G. and Otten U. (1987) An enzyme-linked immunoassay for nerve growth factor (NGF): a tool for studying regulatory mechanisms involved in NGF production in brain and peripheral tissues. J. Neurochem. 48, 1779-1786.
    • (1987) J. Neurochem. , vol.48 , pp. 1779-1786
    • Weskamp, G.1    Otten, U.2
  • 65
    • 0031104806 scopus 로고    scopus 로고
    • A competitive RT-PCR method for the quantitative analysis of cytokine mRNA in mouse tissues
    • Zhou N.-M., Matthys P., Polacek C., Fiten P., Sato A., Billiau A., and Froyen G. (1997) A competitive RT-PCR method for the quantitative analysis of cytokine mRNA in mouse tissues. Cytokine 9, 212-218.
    • (1997) Cytokine , vol.9 , pp. 212-218
    • Zhou, N.-M.1    Matthys, P.2    Polacek, C.3    Fiten, P.4    Sato, A.5    Billiau, A.6    Froyen, G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.