Increased P-selectin gene expression in the liver vasculature and its role in the pathophysiology of neutrophil-induced liver injury in murine endotoxin shock

Journal of Leukocyte Biology

Volumn 63, Issue 3, 1998, Pages 288-296

  Essani, Naeem A ^a   Fisher, Michael A ^a   Simmons, Carol A ^a   Hoover, Jennifer L ^a   Farhood, Anwar ^b   Jaeschke, Hartmut ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Adhesion molecules; Inflammation; Interleukin 1; Tumor necrosis factor

Indexed keywords

GALACTOSAMINE; INTERLEUKIN 1; PADGEM PROTEIN; SALMONELLA ENDOTOXIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; LEUKOCYTE MIGRATION; LIVER INJURY; LIVER SINUSOID; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; VASCULAR ENDOTHELIUM;

ANIMALIA; MURINAE; SALMONELLA; SALMONELLA ABORTUS; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR ABORTUSEQUI;

EID: 0031908271     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.63.3.288     Document Type: Article

References (64)

1. Jaeschke, H., Farhood, A., Smith, C. W. (1990) Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo. FASEB J. 4, 3355-3359.
2. Jaeschke, H., Farhood, A., Bautista, A. P., Spolarics, Z., Spitzer, J. J., Smith, C. W. (1993) Functional inactivation of neutrophils with a Mac-1 (CD11b/CD18) monoclonal antibody protects against ischemia-reperfusion injury in rat liver. Hepatology 17, 915-923.
3. Jaeschke, H., Farhood, A., Smith, C. W. (1991) Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism. Am. J. Physiol. 261, G1051-1056.
4. Hewett, J. A., Schultze, A. E., Vancise, S., Roth, R. A. (1992) Neutrophil depletion protects against liver injury from bacterial endotoxin. Lab. Invest. 66, 347-361.
5. Bautista, A. P. (1997) Chronic alcohol intoxication induces hepatic injury through enhanced macrophage inflammatory protein-2 production and intercellular adhesion molecule-1 expression in the liver. Hepatology 25, 335-342.
6. Maher, J. J., Scott, M. K., Saito, J. M., Burton, M. C. (1997) Adenovirus-mediated expression of cytokine-induced neutrophil chemoattractant in rat liver induces a neutrophilic hepatitis. Hepatology 25, 624-630.
7. Granger, D. N., Kubes, P. (1994) The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion. J. Leukoc. Biol. 55, 662-675.
8. Von Adrian, U. H., Chambers, J. D., McEvoy, L. M. Bargatze, R. F., Arfors, K.-E., Butcher, E. C. (1991) Two step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte β2 integrins in vivo. Proc. Natl. Acad. Sci. USA 88, 7538-7542.
9. Ley, K., Gaehtgens, P., Fennie, C., Singer, M. S., Lasky, L. A., Rosen, S. D. (1991) Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo. Blood 77, 2553-2555.
10. Dore, M., Korthuis, R. J., Granger, D. N., Entman, M. L., Smith, C. W. (1993) P-selectin mediates spontaneous leukocyte rolling in vivo. Blood 82, 1308-1316.
11. Kishimoto, T. K., Jutila, M. A., Berg, E. L., Butcher, E. C. (1989) Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. Science 245, 1238-1241.
12. Lawrence, M. B., Springer, T. A. (1991) Leukocytes roll on a selectin at physiological flow rates: distinction from and prerequisite for adhesion through integrins. Cell 65, 859-873.
13. Lindbom, L., Xie, X., Raud, J., Hedqvist, P. (1992) Chemoattractant-induced firm adhesion of leukocytes to vascular endothelium in vivo is critically dependent on initial leukocyte rolling. Acta Physiol. Scand. 146, 415-421.
14. Smith, C. W. (1992) Transendothelial migration. In: Adhesion: Its Role In Inflammatory Disease (J. M. Harlan, D. Y. Liu, eds.), New York: W. H. Freeman, 85-115.
15. Bevilacqua, M. P., Nelson, R. M. (1993) Selectins. J. Clin. Invest. 91, 379-387.
16. McEver, R. P., Beckstead, J. H., Moore, K. L., Marshall-Carlson, L., Bainton, D. F. (1989) GMP-140, a platelet α-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel Palade bodies. J. Clin. Invest. 84, 92-99.
17. Weller, A., Isenmann, S., Vestweber, D. (1992) Cloning of the mouse endothelial selectins: expression of both E-and P-selectin is inducible by tumor necrosis factor. J. Biol. Chem. 267, 15176-15183.
18. Weyrich, A. S., Ma, X., Lefer, D. J.; Albertine, K. H., Lefer, A. M. (1993) In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury. J. Clin. Invest. 91, 2620-2629.
19. Chen, L. Y., Nichols, W. W., Hendricks, J. B., Yang, B. C., Mehta, J. L. (1994) Monoclonal antibody to P-selectin (PB1.3) protects against myocardial reperfusion injury in the dog. Cardiovasc. Res. 28, 1414-1422.
20. Mulligan, M. S., Policy, M. J., Bayer, R. J., Nunn, M. F., Paulson, J. C., Ward, P. A. (1992) Neutrophil-dependent acute lung injury: requirement for P-selectin (GMP-140). J. Clin. Invest. 90, 1600-1607.
21. Carden, D. L., Young, J. A., Granger, D. N. (1993) Pulmonary microvascular injury after intestinal ischemia-reperfusion: role of P-seleetin. J. Appl. Physiol. 75, 2529-2534.
22. Davenbeck, K. L., Gauthier, T. W., Albertine, K. H., Lefer, A. M. (1994) Role of P-selectin in microvascular leukocyte-endothelial interaction in splanchnic ischemia-reperfusion. Am. J. Physiol. 267, H622-H630.
23. Bienvenu, K., Granger, D. N. (1993) Molecular determinants of shear rate-dependent leukocyte adhesion in postcapillary venules. Am. J. Physiol. 264, H1504-H1508.
24. Steinhoff, G., Behrend, M., Schrader, B., Duijvestijn, A. M., Wonigeit, K. (1993) Expression patterns of leukocyte adhesion ligand molecules on human liver endothelia. Am. J. Pathol. 142, 481-488.
25. Irving, M. G., Roll, F. J., Huang, S., Bissell, D. M. (1984) Characterization and culture of sinusoidal endothelium from normal rat liver: Lipoprotein uptake and collagen phenotype. Gastroenterol. 87, 1233-1247.
26. Wisse, E. (1972) An ultrastructural characterization of the endothelial cell in the rat liver sinusoid under normal and various experimental conditions, as a contribution to the distinction between endothelial and Kupffer cells. J. Ultrastruct. Res. 38, 528-562.
27. Essani, N. A., McGuire, G. M., Manning, A. M., Jaeschke, H. (1995) Differential induction of mRNA for ICAM-1 and selectins in hepatocytes, Kupffer cells and endothelial cells during endotoxemia. Biochem. Biophys. Res. Commun. 211, 74-82.
28. Garcia-Criado, F. J., Toledo-Pereyra, L. H., Lopez-Neblina, F., Phillips, M. L., Paez-Rollys, A., Misawa, K. (1995) Role of P-selectin in total hepatic ischemia and reperfusion. Am. Coll. Surg. 181, 327-334.
29. Essani, N. A., Fisher, M. A., Farhood, A., Manning, A. M., Smith, C. W., Jaeschke, H. (1995) Cytokine-induced hepatic intercellular adhesion molecule-1 (ICAM-1) mRNA expression and its role in the pathophysiology of murine endotoxin shock and acute liver failure. Hepatology 21, 1632-1639.
30. Schlayer, H. J., Laaff, H., Peters, T., Woort-Menker, M., Estler, H. C., Karck, U., Schaefer, H. E., Decker, K. (1988) Involvement of tumor necrosis factor in endotoxin-triggered neutrophil adherence to sinusoidal endothelial cells of mouse liver and its modulation in acute phase. J. Hepatol. 7, 239-249.
31. Chosay, J. C., Essani, N. A., Dunn, C. J., Jaeschke, H. (1997) Neutrophil margination and extravasation in sinusoids and venules of the liver during endotoxin-induced injury. Am. J. Physiol. 272, G1195-G1200.
32. Essani, N. A., Bajt, M. L., Vonderfecht, S. L., Farhood, A., Jaeschke, H. (1997) Transcriptional activation of vascular cell adhesion molecule-1 (VCAM-1) gene in vivo and its role in the pathophysiology of neutrophil-induced liver injury in murine endotoxin shock. J. Immunol. 158, 5941-5948.
33. Bullard, D. C., Quin, L., Lorenzo, I., Quinlin, W. M., Doyle, N. A., Bosse, R., Vestweber, D., Doerschuk, C. M., Beaudet, A. L. (1995) P-selectin/ ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli. J. Clin. Invest. 95, 1782-1788.
34. Chomczynski, P., Sacchi, N. (1987) Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
35. Maniatis, T., Fritsch, E. F., Sambrook, J. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbour Laboratory Press.
36. Sanders, W. E., Wilson, R. W., Ballantyne, C. M., Beaudet, A. L. (1992) Molecular cloning and analysis of in vivo expression of murine P-selectin. Blood 80, 795-800.
37. 2 integrins and intercellular adhesion molecule-1. Shock 6, 345-350.
38. Krawisz, J. E., Sharon, P., Stenson, W. F. (1984) Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Gastroenlerol. 87, 1344-1350.
39. Ruco, L. P., Meltzer, M. S. (1978) Defective tumoricidal capacity of macrophages from C3H/HeJ mice. J. Immunol. 120, 329-334.
40. Beutler, B., Krochin, N., Milsark, I. W., Luedke, C., Cerami, A. (1986) Control of cachectin (tumor necrosis factor) synthesis: Mechanism of endotoxin resistance. Science 232, 977-980.
41. Essani, N. A., Fisher, M. A., Jaeschke, H. (1997) Inhibition of NF-κB activation by dimethyl sulfoxide correlates with suppression of TNF-α formation, reduced ICAM-1 gene transcription and protection against endotoxin-induced liver injury. Shock 7, 90-96.
42. Pan, J., McEver, R. P. (1994) Characterization of the promoter for the human P-selectin gene. J. Biol. Chem. 268, 22600-22608.
43. Hahne, M., Jäger, U., Isenmann, S., Hallmann, R., Vestweber, D. (1992) Five tumor necrosis factor-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes. J. Cell Biol. 121, 655-664.
44. Collins, T., Read, M. A., Neish, A. S., Whitley, M. Z., Thanos, D., Maniatis, T. (1995) Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine-inducible enhancers. FASEB J. 9, 899-909.
45. Essani, N. A., McGuire, G. M., Manning, A. M., Jaeschke, H. (1996) Endotoxin-induced activation of the nuclear transcription factor κB and expression of E-selectin messenger RNA in hepatocytes, Kupffer cells, and endothelial cells in vivo. J. Immunol. 156, 2956-2963.
46. Jaeschke, H., Essani, N. A., Fisher, M. A., Vonderfecht, S. L., Farhood, A., Smith, C. W. (1996) Release of soluble intercellular adhesion molecule 1 into bile and serum in murine endotoxin shock. Hepatology 23, 530-536.
47. Bosse, R., Vestweber, D. (1994) Only simultaneous blocking of the L-and P-selectin completely inhibits neutrophil migration into mouse peritoneum. Eur. J. Immunol. 24, 3019-3024.
48. Jaeschke, H., Smith, C. W. (1997) Mechanisms of neutrophil-induced parenchymal cell injury. J. Leukoc. Biol. 61, 647-653.
49. Farhood, A., McGuire, G. M., Manning, A. M., Miyasaka, M., Smith, C. W., Jaeschke, H. (1995) Intercellular adhesion molecule-1 (ICAM-1) expression and its role in neutrophil-induced ischemia-reperfusion injury in rat liver. J. Leukoc. Biol. 57, 368-374.
50. Vollmar, B., Glasz, J., Menger, M. D., Messmer, K. (1995) Leukocytes contribute to hepatic ischemia-reperfusion injury via intercellular adhesion molecule-1-mediated venular adherence. Surgery 117, 195-200.
51. McCuskey, R. S. (1993) Hepatic microvascular responses to endotoxemia and sepsis. Prog. Appl. Microcirc. 19, 76-84.
52. Zhang, J. X., Pegoli, W., Clemens, M. G. (1994) Endothelin-1 induces direct constriction of hepatic sinusoids. Am. J. Physiol. 266, G624-G632.
53. Worthen, G. S., Schwab, B., Elson, E. L., Downey, G. P. (1989) Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries. Science 245, 183-186.
54. Zhang, J. X., Jones, D. V., Clemens, M. G. (1994) Effect of activation on neutrophil-induced hepatic microvascular injury in isolated rat liver. Shock 1, 273-278.
55. Bilzer, M., Lauterburg, B. H. (1994) Oxidant stress and potentiation of ischemia-reperfusion injury to the perfused rat liver by human polymorphonuclear leukocytes. J. Hepatol. 20, 473-477.
56. Thornton, A. J., Ham, J., Kunkel, S. L. (1992) Kupffer cell-derived cytokines induce the synthesis of a leukocyte chemotactic peptide, interleukine-8, in human hepatoma and primary hepatocyte culture. Hepatology 15, 1112-1122.
57. Zhang, P., Xie, M., Zagorski, J., Spitzer, J. A. (1995) Attenuation of hepatic neutrophil sequestration by anti-CINC antibody in endotoxic rats. Shock 4, 262-268.
58. Ohira, H., Ueno, T., Torimura, T., Tanikawa, K., Kasukawa, R. (1995) Leukocyte adhesion molecules in the liver and plasma cytokine levels in endotoxin-induced rat liver injury. Scand. J. Gastroenterol. 30, 1027-1035.
59. Maroushek-Boury, N., Czuprynski, C. J. (1995) Listeria monocytogenes infection increases neutrophil adhesion and damage to a murine hepatocyte cell line in vitro. Immunol. Lett. 46, 111-116.
60. Nagendra, A. R., Mickelson, J. K., Smith, C. W. (1997) CD18 integrin and intercellular adhesion molecule-1 (CD54)-dependent neutrophil adhesion to cytokine-stimulated human hepatocytes. Am. J. Physiol. 272, G408-G416.
61. Jaeschke, H., Farhood, A. (1991) Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver in vivo. Am. J. Physiol. 260, G355-G362.
62. Liu, P., McGuire, G. M., Fisher, M. A., Farhood, A., Smith, C. W., Jaeschke, H. (1995) Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia. Shock 3, 56-62.
63. Gibbs, A. A. L., Weiser, M. R., Kobzik, L., Valeri, C. R., Shepro, D., Hechtman, H. B. (1996) P-selectin mediates intestinal ischemic injury by enhancing complement deposition. Surgery 119, 652-656.
64. Jaeschke, H., Farhood, A., Bautista, A. P., Spolarics, Z., Spitzer, J. J. (1993) Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia. Am. J. Physiol. 264, G801-G809.