Loss of CD4+ T cells in human immunodeficiency virus type 1-infected chimpanzees is associated with increased lymphocyte apoptosis

Journal of Virology

Volumn 72, Issue 6, 1998, Pages 4623-4632

  Davis, Ian C ^a   Girard, Marc ^b   Fultz, Patricia N ^b,c  

^a UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSTIMULATION; MALE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; T LYMPHOCYTE ACTIVATION; VIRUS RESISTANCE;

EID: 0031901314     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.6.4623-4632.1998     Document Type: Article

References (54)

1. Ameisen, J. C. 1995. From cell activation to cell depletion. The programmed cell death hypothesis of AIDS pathogenesis, p. 139-163. In J.-M. Andrieu and W. Lu (ed.), Cell activation and apoptosis in HIV infection. Plenum Press, New York, N.Y.
2. Ameisen, J. C., and A. Capron. 1991. Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis. Immunol. Today 12:102-105.
3. Antoni, B. A., P. Sabbatini, A. B. Rabson, and E. White. 1995. Inhibition of apoptosis in human immunodeficiency virus-infected cells enhances virus production and facilitates persistent infection. J. Virol. 69:2384-2392.
4. Ascher, M. S., and H. W. Sheppard. 1988. AIDS as immune system activation: a model for pathogenesis. Clin. Exp. Immunol. 73:165-167.
5. + T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor. J. Exp. Med. 185:55-64.
6. Bentin, J., C. Tsoukas, J. A. McCutchan, S. E. Spector, D. D. Richman, and J. H. Vaughan. 1989. Impairment in T-lymphocyte responses during early infection with the human immunodeficiency virus. J. Clin. Immunol. 9:159-168.
7. Biberfeld, P., A. Porwit-Ksiazek, D. Bottiger, L. Morfeldt-Manson, and G. Biberfeld. 1985. Immunohistopathology of lymph nodes in HTLV-III infected homosexuals with persistent adenopathy or AIDS. Cancer Res. 45: 4665s-4670s.
8. + T lymphocytes during HIV infection. J. Immunol. 156:2282-2293.
9. Carbonari, M., M. Cibati, M. Cherchi, D. Sbarigia, A. M. Pesce, L. Dell'Anna, A. Modica, and M. Fiorilli. 1994. Detection and characterisation of apoptotic peripheral blood lymphocytes in human immunodeficiency virus infection and cancer chemotherapy by a novel flow immunocytometric method. Blood 83:1268-1277.
10. + cells. AIDS Res. Hum. Retroviruses 11:789-795.
11. Chinnaiyan, A. M., C. Woffendin, V. M. Dixit, and G. J. Nabel. 1997. The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication. Nat. Med. 3:333-337.
12. + antigen-specific T cells to undergo apoptosis by HIV-infected monocytes. A two-step mechanism involving the gp120 molecule. J. Clin. Invest. 99:257-266.
13. Estaquier, J., T. Idziorek, F. DeBels, F. Barré-Sinoussi, B. Hurtrel, A.-M. Aubertin, A. Venet, M. Mehtali, E. Muchmore, P. Michel, Y. Mouton, M. Girard, and J. C. Ameisen. 1994. Programmed cell death and AIDS: significance of T cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections. Proc. Natl. Acad. Sci. USA 91:9431-9435.
14. Finkel, T. H., G. Tudor-Williams, N. K. Banda, M. F. Cotton, T. Curiel, C. Monks, T. W. Baba, R. M. Ruprecht, and A. Kupfer. 1995. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat. Med. 1:129-134.
15. Fultz, P. N. 1993. Nonhuman primate models for AIDS. Clin. Infect. Dis. 17:5230-5235.
16. Fultz, P. N., J. C. Gluckman, E. Muchmore, and M. Girard. 1992. Transient increases in numbers of infectious cells in an HIV-infected chimpanzee following immune stimulation. AIDS Res. Hum. Retroviruses 8:313-317.
17. + lymphocytopenia and thrombocytopenia in a chimpanzee persistently infected with human immunodeficiency virus type 1. J. Infect. Dis. 163:441-447.
18. Fultz, P. N., A. Srinivasan, C. R. Greene, D. Butler, R. B. Swenson, and H. M. McClure. 1987. Superinfection of a chimpanzee with a second strain of human immunodeficiency virus. J. Virol. 61:4026-4029.
19. Gavrieli, Y., Y. Sherman, and S. A. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
20. Gendelman, H. E., G. D. Ehrlich, L. M. Baca, S. Conley, J. Ribas, D. C. Kalter, M. S. Meltzer, B. J. Poiesz, and P. Nara. 1991. The inability of human immunodeficiency virus to infect chimpanzee monocytes can be overcome by serial viral passage in vivo. J. Virol. 65:3853-3863.
21. Girard, M., J. Mahoney, L. Rimsky, F. Barré-Sinoussi, E. Muchmore, K. Weinhold, and P. Fultz. 1992. HIV-1 genital infection: a chimpanzee model, p. 75-79. In M. Girard and L. Valette (ed.), Retroviruses of human AIDS and related animal diseases. Fondation Merieux, Lyon, France.
22. Giorgi, J. V., and R. Detels. 1989. T-cell subset alterations in HIV-infected homosexual men: NIAID multicenter AIDS cohort study. Clin. Immunol. Immunopathol. 52:10-18.
23. Gougeon, M.-L., S. Garcia, J. Heeney, R. Tschopp, H. Lecoeur, D. Guetard, V. Rame, C. Dauguet, and L. Montagnier. 1993. Programmed cell death in AIDS-related HIV and SIV infections. AIDS Res. Hum. Retroviruses 9:553-563.
24. Gougeon, M.-L., H. Lecoeur, F. Boudet, E. Ledru, S. Marzabal, S. Boullier, R. Roue, S. Nagata, and J. Heeney. 1997. Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype. J. Immunol. 158:2964-2976.
25. Gougeon, M.-L., H. Lecoeur, A. Dulioust, M.-G. Enouf, M. Crouvoisier, C. Goujard, T. Debord, and L. Montagnier. 1996. Programmed cell death in peripheral lymphocytes from HIV-infected persons. Increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression. J. Immunol. 156:3509-3520.
26. Heeney, J., R. Jonker, W. Koornstra, R. Dubbes, H. Niphuis, A.-M. DiRienzo, M.-L. Gougeon, and L. Montagnier. 1993. The resistance of HIV-infected chimpanzees to progression to AIDS correlates with absence of HIV-related T-cell dysfunction. J. Med. Primatol. 22:194-200.
27. Hirsch, V. M., and P. R. Johnson. 1994. Pathogenic diversity of simian immunodeficiency viruses. Virus Res. 32:183-203.
28. Ho, D. D., A. U. Neumann, A. S. Perelson, W. Chen, J. M. Leonard, and M. Markowitz. 1995. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373:123-126.
29. Johnson, B. K., G. A. Stone, M. S. Godec, D. M. Asher, D. C. Gajdusek, and C. J. Gibbs. 1993. Long-term observations of human immunodeficiency virus-infected chimpanzees. AIDS Res. Hum. Retroviruses 9:375-378.
30. Katsikis, P. D., E. S. Wunderlich, C. A. Smith, L. A. Herzenberg, and L. A. Herzenberg. 1995. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J. Exp. Med. 181:2029-2036.
31. Laurent-Crawford, A. G., B. Krust, S. Muller, Y. Riviere, M.-A. Rey-Cuille, J.-M. Bechet, L. Montagnier, and A. G. Hovanessian. 1991. The cytopathic effect of HIV is associated with apoptosis. Virology 185:829-839.
32. Levy, J. A. 1993. Pathogenesis of human immunodeficiency virus infection. Microbiol. Rev. 57:183-289.
33. + T cells from HIV-infected persons. J. Immunol. 153:412-420.
34. Li, C. J., D. J. Friedman, C. Wang, V. Metelev, and A. B. Pardee. 1995. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 268:429-431.
35. + T cells in vitro: differential induction of apoptosis in these cells. J. Immunol. 152:330-342.
36. Mellors, J. W., L. A. Kingsley, C. R. Rinaldo, J. A. Todd, B. S. Hoo, R. P. Kokka, and P. Gupta. 1995. Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion. Ann. Intern. Med. 122:573-579.
37. Meyaard, L., S. A. Otto, R. R. Jonker, M. J. Mijnster, R. P. M. Keet, and F. Miedema. 1992. Programmed death of T cells in HIV-1 infection. Science 257:217-219.
38. Meyaard, L., S. A. Otto, I. P. M. Keet, M. T. L. Roos, and F. Miedema. 1994. Programmed death of T cells in human immunodeficiency virus infection: no correlation with progression to disease. J. Clin. Invest. 93:982-988.
39. Muro-Cacho, C. A., G. Pantaleo, and A. S. Fauci. 1995. Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J. Immunol. 154:5555-5566.
40. Novembre, F. J., M. Saucier, D. C. Anderson, S. A. Klumpp, S. P. O'Neil, C. R. Brown, C. E. Hart, P. C. Guenthner, R. B. Swenson, and H. M. McClure. 1997. Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1. J. Virol. 71:4086-4091.
41. Oyaizn, N., and S. Pahwa. 1995. Role of apoptosis in HIV disease pathogenesis. J. Clin. Immunol. 15:217-231.
42. Pandolfi, F., M. Pierdominici, A. Oliva, G. D'Offizi, I. Mezzaroma, B. Mollicone, A. Giovannetti, L. Rainaldi, I. Quinti, and F. Aiuti. 1995. Apoptosis-related monality in vitro of mononuclear cells from patients with HIV infection correlates with disease severity and progression. J. Acquired Immune Defic. Syndr. Hum. Retrovirol. 9:450-458.
43. Pantaleo, G., and A. S. Fauci. 1995. New concepts in the immunopathogenesis of HIV infection. Annu. Rev. Immunol. 13:487-512.
44. + T cell clones during primary HIV infection. Proc. Natl. Acad. Sci. USA 94:9848-9853.
45. Rey-Cuille, M.-A., J. Golobru, A. Laurent-Crawford, B. Krust, L. Montagnier, and A. G. Hovanessian. 1994. HIV-2 EHO isolate has a divergent envelope gene and induces single cell killing by apoptosis. Virology 202:471-476.
46. Rothen, M., S. Gratzl, H. H. Hirsch, and C. Moroni. 1997. Apoptosis in HIV-infected individuals is an early marker occurring independently of high viremia. AIDS Res. Hum. Retroviruses 13:771-779.
47. Schmid, I., C. H. Uittenbogaart, B. Keld, and J. V. Giorgi. 1994. A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry. J. Immunol. Methods 170:145-157.
48. Schuitemaker, H., L. Meyaard, N. A. Kootstra, R. Dubbes, S. A. Otto, M. Tersmette, J. L. Heeney, and F. Miedema. 1993. Lack of T cell dysfunction and programmed cell death in human immunodeficiency virus type 1-infected chimpanzees correlates with absence of monocytotropic variants. J. Infect. Dis. 168:1140-1147.
49. Villinger, F., S. S. Brar, G. T. Brice, N. F. Chikkala, F. J. Novembre, A. E. Mayne, S. Bucur, C. D. Hillyer, and A. A. Ansari. 1997. Immune and hematopoietic parameters in HIV-1-infected chimpanzees during clinical progression towards AIDS. J. Med. Primatol. 26:11-18.
50. Watanabe, M., D. J. Ringler, P. N. Fultz, J. J. MacKey, J. E. Boyson, C. G. Levine, and N. L. Letvin. 1991. A chimpanzee-passaged human immunodeficiency virus isolate is cytopathic for chimpanzee cells but does not induce disease. J. Virol. 65:3344-3348.
51. Wei, Q., and P. N. Fultz. 1998. Extensive diversification of human immunodeficiency virus type 1 subtype B strains during dual infection of a chimpanzee that progressed to AIDS. J. Virol. 72:3005-3017.
52. Wei, X., S. K. Ghosh, M. E. Taylor, V. A. Johnson, E. A. Emini, P. Deutsch, J. D. Lifson, S. Bonhoeffer, M. A. Nowak, B. H. Hahn, M. S. Saag, and G. M. Shaw. 1995. Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373:117-122.
53. Westendorp, M. O., R. Frank, C. Ochsenbauer, K. Stricker, J. Dhein, H. Walczak, K.-M. Debatin, and P. H. Krammer. 1995. Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 375:497-500.
54. Xu, X.-N., G. R. Screaton, F. M. Gotch, T. Dong, R. Tan, N. Almond, B. Walker, R. Stebbings, K. Kent, S. Nagata, J. E. Stott, and A. J. McMichael. 1997. Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells. J. Exp. Med. 186:7-16.