Liquid chromatography/nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry identification of novel metabolites of the multidrug resistance modulator LY335979 in rat bile and human liver microsomal incubations

Drug Metabolism and Disposition

Volumn 26, Issue 1, 1998, Pages 42-51

  Ehlhardt, William J ^a   Woodland, Joseph M ^b   Baughman, Todd M ^b   Vandenbranden, Mark ^b   Wrighton, Steven A ^b   Kroin, J Stan ^b   Norman, Bryan H ^b   Maple, Steven R ^b  

^a ELI LILLY AND COMPANY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; ZOSUQUIDAR;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE ACID METABOLISM; BIOTRANSFORMATION; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DRUG DEGRADATION; DRUG METABOLISM; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; BILE; CATHETERIZATION; CHROMATOGRAPHY, LIQUID; DIBENZOCYCLOHEPTENES; DRUG RESISTANCE, MULTIPLE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MICROSOMES, LIVER; QUINOLINES; RATS; RATS, INBRED F344; TIME FACTORS;

EID: 0031894853     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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