Selective inhibition of type-I geranylgeranyltransferase in vitro and in whole cells by CAAL peptidomimetics

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 3, 1998, Pages 293-299

  Qian, Yimin ^a   Vogt, Andreas ^a   Vasudevan, Anil ^a   Sebti, Saïd M ^a   Hamilton, Andrew D ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GERANYLTRANSFERASE; PEPTIDE DERIVATIVE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CELL CYCLE G1 PHASE; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SPECIFICITY; ISOPRENYLATION; NONHUMAN; PROTEIN PROCESSING;

3T3 CELLS; ALKYL AND ARYL TRANSFERASES; ANIMALS; ENZYME INHIBITORS; GTP-BINDING PROTEINS; MICE; OLIGOPEPTIDES; PROTEIN ISOPRENYLATION; RAP GTP-BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0031894821     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)10040-2     Document Type: Article

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