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Volumn 12, Issue 1, 1998, Pages 146-156

The 20-kilodalton (kDa) human growth hormone (hGH) differs from the 22- kDa hGH in the complex formation with cell surface hGH receptor and hGH- binding protein circulating in human plasma

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RECEPTOR; HUMAN GROWTH HORMONE;

EID: 0031893308     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.12.1.0054     Document Type: Article
Times cited : (66)

References (37)
  • 2
    • 0025999498 scopus 로고
    • Growth hormone heterogenity: Genes, isoforms, variants, and binding proteins
    • Baumann G 1991 Growth hormone heterogenity: genes, isoforms, variants, and binding proteins. Endocr Rev 12:424-449
    • (1991) Endocr Rev , vol.12 , pp. 424-449
    • Baumann, G.1
  • 3
    • 0018819667 scopus 로고
    • The 20,000-dalton variant of human growth hormone: Location of the amino acid deletions
    • Lewis UJ, Bonewald LF, Lewis LJ 1980 The 20,000-dalton variant of human growth hormone: location of the amino acid deletions. Biochem Biophys Res Commun 92:511-516
    • (1980) Biochem Biophys Res Commun , vol.92 , pp. 511-516
    • Lewis, U.J.1    Bonewald, L.F.2    Lewis, L.J.3
  • 4
    • 0019785870 scopus 로고
    • Human growth hormone DNA sequence and mRNA structure: Possible alternative splicing
    • DeNoto FM, Moore DD, Goodman HM 1981 Human growth hormone DNA sequence and mRNA structure: possible alternative splicing. Nucleic Acids Res 9:3719-3730
    • (1981) Nucleic Acids Res , vol.9 , pp. 3719-3730
    • DeNoto, F.M.1    Moore, D.D.2    Goodman, H.M.3
  • 8
    • 0026332810 scopus 로고
    • Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule
    • Cunningham BC, Ultsch M, DeVos AM, Mulkerrin MG, Clauser KR, Wells JA 1991 Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule. Science 254:821-825
    • (1991) Science , vol.254 , pp. 821-825
    • Cunningham, B.C.1    Ultsch, M.2    DeVos, A.M.3    Mulkerrin, M.G.4    Clauser, K.R.5    Wells, J.A.6
  • 9
    • 0024403619 scopus 로고
    • High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis
    • Cunningham BC, Wells JA 1989 High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. Science 244:1081-1085
    • (1989) Science , vol.244 , pp. 1081-1085
    • Cunningham, B.C.1    Wells, J.A.2
  • 10
    • 0030050701 scopus 로고    scopus 로고
    • Binding in the growth hormone receptor complex
    • Wells JA 1996 Binding in the growth hormone receptor complex. Proc Natl Acad Sci USA 93:1-6
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1-6
    • Wells, J.A.1
  • 11
    • 0026598960 scopus 로고
    • Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
    • De Vos AM, Ultsch M, Kossiakoff AA 1992 Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 255:306-312
    • (1992) Science , vol.255 , pp. 306-312
    • De Vos, A.M.1    Ultsch, M.2    Kossiakoff, A.A.3
  • 15
    • 0028273518 scopus 로고
    • The stoichiometry of growth hormone-binding protein complexes in human plasma: Comparison with cell surface receptors
    • Baumann G, Lowman HB, Mercado M, Wells JA 1994 The stoichiometry of growth hormone-binding protein complexes in human plasma: comparison with cell surface receptors. J Clin Endocrinol Metab 78:1113-1118
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1113-1118
    • Baumann, G.1    Lowman, H.B.2    Mercado, M.3    Wells, J.A.4
  • 16
    • 84969001783 scopus 로고
    • The attractions of proteins for small molecules and ions
    • Scatchard G 1949 The attractions of proteins for small molecules and ions. Ann NY Acad Sci 51:660-672
    • (1949) Ann NY Acad Sci , vol.51 , pp. 660-672
    • Scatchard, G.1
  • 18
    • 0027943686 scopus 로고
    • Crystal structure of the catalytic domain of the β-1,4-glycanase cex from cellulomonas fimi
    • White A, Withers SG, Gilkes NR, Rose DR 1994 Crystal structure of the catalytic domain of the β-1,4-glycanase cex from cellulomonas fimi. Biochemistry 33:12546-12552
    • (1994) Biochemistry , vol.33 , pp. 12546-12552
    • White, A.1    Withers, S.G.2    Gilkes, N.R.3    Rose, D.R.4
  • 19
    • 0029770041 scopus 로고    scopus 로고
    • Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 Å resolution
    • Sundström M, Lundqvist T, Rödin J, Giebel LB, Milligan D, Norstedt G 1996 Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 Å resolution. J Biol Chem 271:32197-32203
    • (1996) J Biol Chem , vol.271 , pp. 32197-32203
    • Sundström, M.1    Lundqvist, T.2    Rödin, J.3    Giebel, L.B.4    Milligan, D.5    Norstedt, G.6
  • 20
    • 0028898944 scopus 로고
    • Amino acids of the human growth hormone receptor that are required for proliferation and Jak-STAT signaling
    • Wang Y-D, Wood WI 1995 Amino acids of the human growth hormone receptor that are required for proliferation and Jak-STAT signaling. Mol Endocrinol 9:303-311
    • (1995) Mol Endocrinol , vol.9 , pp. 303-311
    • Wang, Y.-D.1    Wood, W.I.2
  • 22
    • 0027135143 scopus 로고
    • The growth hormone (GH)-binding protein cloned from human IM-9 lymphocytes modulates the down-regulation of GH receptors by 22- and 20-kilodalton human GH in IM-9 lymphocytes and the biological effects of the hormone in Nb2 lymphoma cells
    • Hansen BS, Hjorth S, Welinder BS, Skriver L, De Meyts P 1993 The growth hormone (GH)-binding protein cloned from human IM-9 lymphocytes modulates the down-regulation of GH receptors by 22- and 20-kilodalton human GH in IM-9 lymphocytes and the biological effects of the hormone in Nb2 lymphoma cells. Endocrinology 133:2809-2817
    • (1993) Endocrinology , vol.133 , pp. 2809-2817
    • Hansen, B.S.1    Hjorth, S.2    Welinder, B.S.3    Skriver, L.4    De Meyts, P.5
  • 23
    • 0023930989 scopus 로고
    • The circulating growth hormone (GH)-binding protein complex: A major constituent of plasma GH in man
    • Baumann G, Amburn K, Shaw MA 1988 The circulating growth hormone (GH)-binding protein complex: a major constituent of plasma GH in man. Endocrinology 122:976-984
    • (1988) Endocrinology , vol.122 , pp. 976-984
    • Baumann, G.1    Amburn, K.2    Shaw, M.A.3
  • 24
    • 0022000726 scopus 로고
    • Slow metabolic clearence rate of the 20,000-dalton variant of human growth hormone: Implications for biological activity
    • Baumann G, Stolar MW, Buchanan TA 1985 Slow metabolic clearence rate of the 20,000-dalton variant of human growth hormone: implications for biological activity. Endocrinology 117:1309-1313
    • (1985) Endocrinology , vol.117 , pp. 1309-1313
    • Baumann, G.1    Stolar, M.W.2    Buchanan, T.A.3
  • 25
    • 0026630440 scopus 로고
    • Growth hormone (GH) binding protein and GH interactions in vivo in the guinea pig
    • Fairhall KM, Carmignac DF, Robinson ICAF 1992 Growth hormone (GH) binding protein and GH interactions in vivo in the guinea pig. Endocrinology 131:1963-1969
    • (1992) Endocrinology , vol.131 , pp. 1963-1969
    • Fairhall, K.M.1    Carmignac, D.F.2    Robinson, I.C.A.F.3
  • 26
    • 0019997618 scopus 로고
    • The biological half-life of human growth hormone and a biologically active 20,000-dalton variant in mouse blood
    • Sigel MB, VanderLaan WP, Kobrin MS, VanderLaan EF, Thorpe NA 1982 The biological half-life of human growth hormone and a biologically active 20,000-dalton variant in mouse blood. Endocr Res Commun 9:67-77
    • (1982) Endocr Res Commun , vol.9 , pp. 67-77
    • Sigel, M.B.1    VanderLaan, W.P.2    Kobrin, M.S.3    VanderLaan, E.F.4    Thorpe, N.A.5
  • 29
    • 84995826606 scopus 로고
    • Receptor dimerization determines the effect of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes
    • Ilond MM, Damholt AB, Cunningham BA, Wells JA, De Meyts P, Shymko RM 1994 Receptor dimerization determines the effect of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes. Endocrinology 134:2397-2403
    • (1994) Endocrinology , vol.134 , pp. 2397-2403
    • Ilond, M.M.1    Damholt, A.B.2    Cunningham, B.A.3    Wells, J.A.4    De Meyts, P.5    Shymko, R.M.6
  • 31
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Köhler G, Milstein C 1975 Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256:495-497
    • (1975) Nature , vol.256 , pp. 495-497
    • Köhler, G.1    Milstein, C.2
  • 32
    • 0025884056 scopus 로고
    • Efficient selection for high- Expression transfectants with a novel eukaryotic vector
    • Niwa H, Yamamura K, Miyazaki J 1991 Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:193-200
    • (1991) Gene , vol.108 , pp. 193-200
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 33
    • 0030727296 scopus 로고    scopus 로고
    • The full agonistic effect of recombinant 20 kDa human growth hormone (hGH) on CHO cells stably transfected with hGH receptor cDNA
    • Wada M, Ikeda M, Takahashi Y, Asada N, Chang K-T, Takahashi M, Honjo M 1997 The full agonistic effect of recombinant 20 kDa human growth hormone (hGH) on CHO cells stably transfected with hGH receptor cDNA. Mol Cell Endocrinol 133:99-107
    • (1997) Mol Cell Endocrinol , vol.133 , pp. 99-107
    • Wada, M.1    Ikeda, M.2    Takahashi, Y.3    Asada, N.4    Chang, K.-T.5    Takahashi, M.6    Honjo, M.7
  • 34
    • 0014010845 scopus 로고
    • The release of enzyme by osmotic shock from Escherichia coli in exponential phase
    • Nossal NG, Heppel LA 1966 The release of enzyme by osmotic shock from Escherichia coli in exponential phase. J Biol Chem 241:3055-3062
    • (1966) J Biol Chem , vol.241 , pp. 3055-3062
    • Nossal, N.G.1    Heppel, L.A.2
  • 35
    • 15644364751 scopus 로고
    • October Biosym/MSI, San Diego, CA
    • Insight II Use Guide, October 1995 Biosym/MSI, San Diego, CA
    • (1995) Insight II Use Guide
  • 36
    • 0008792208 scopus 로고
    • October Biosym/MSI, San Diego, CA
    • Homology User Guide, October 1995 Biosym/MSI, San Diego, CA
    • (1995) Homology User Guide
  • 37
    • 0015222647 scopus 로고
    • The interpretation of protein's structures: Estimation of state accessibility
    • Lee B, Richards FM 1971 The interpretation of protein's structures: estimation of state accessibility. J Mol Biol 55:379-400
    • (1971) J Mol Biol , vol.55 , pp. 379-400
    • Lee, B.1    Richards, F.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.