Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification

Development

Volumn 125, Issue 5, 1998, Pages 845-856

  Rhinn, Muriel ^a   Dierich, Andrée ^a   Shawlot, William ^b   Behringer, Richard R ^b   Meur, Marianne Le ^a   Ang, Siew Lan ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Chimera; Drosophila; ES cell; Explant; Forebrain; Midbrain; Mouse; Orthodenticle; Otx2; Patterning

Indexed keywords

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CHIMERA; DEVELOPMENTAL GENETICS; EMBRYO; ENDODERM; FOREBRAIN; HOMEOBOX; MESENCEPHALON; MOUSE; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; VISCERA;

ANIMALS; CARRIER PROTEINS; CELL LINE; CHIMERA; DROSOPHILA; ECTODERM; EMBRYONIC INDUCTION; ENDODERM; FEMALE; FOLLISTATIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; GENES, INSECT; GLYCOPROTEINS; HOMEODOMAIN PROTEINS; IN SITU HYBRIDIZATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MESENCEPHALON; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; NERVE TISSUE PROTEINS; OTX TRANSCRIPTION FACTORS; PREGNANCY; PROSENCEPHALON; PROTEINS; TRANS-ACTIVATORS;

ANIMALIA;

EID: 0031891150     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. -/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development 121, 3279-3290.
2. Albano, R. M., Arkell, R., Beddington, R. S. and Smith, J. C. (1994). Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain. Development 120, 803-813.
3. Ang, S.-L. and Rossant, J. (1993). Anterior mesendoderm induces mouse Engrailed genes in explant cultures. Development 118, 139-149.
4. Ang, S.-L., Conlon, R. A., Jin, O. and Rossant, J. (1994). Positive and negative signals from mesoderm regulates the expression of mouse Otx2 in ectoderm explants. Development 120, 2979-2989.
5. Ang, S.-L., Jin, O., Rhinn, M., Daigle, N., Stevenson, L. and Rossant, J. (1996). A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development 122, 243-252.
6. Bally-Cuif, L., Gusilano, M., Broccoli, V. and Boncinelli, E. (1995). c-otx2 is expressed in two different phases of gastrulation and is sensitive to retinoic acid treatment in chick embryo. Mech. Dev. 49, 49-63.
7. Barnes, J. D., Crosby, J. L., Jones, C. M., Wright, C. V. E. and Hogan, B. L. M. (1994). Embryonic expression of Lim-1, the mouse homolog of Xenopus XLim-1, suggests a role in lateral mesoderm differentiation and neurogenesis. Dev. Biol. 161, 168-178.
8. Beddington, R. S. P. and Robertson, E. J. (1989). An assessment of the developmental potential of embryonic stem cells in the midgestation embryo. Development 105, 733-737.
9. Beddington, R. S. P, Morgenstein, J., Land, H. and Hogan, A. (1989). An in situ transgenic enzyme marker for the midgestation mouse embryo and the visualization of the inner cell mass clones during early organogenesis. Development 106, 37-46.
10. Biben, C., Stanley, E., Fabri, L., Kotecha, K., Rhinn, M., Drinkwater, K., Wang, C., Nash, A., Hilton, D., Ang, S.-L., Mohun, T. and Harvey, R. P. (1997). A murine cerberus homologue (mCer-1) expressed in anterior primitive endoderm and embryonic mesendoderm during gastrulation. Dev. Biol., in press.
11. Blitz, I. C. and Cho K. W. Y. (1995). Anterior neurectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene orthodenticle. Development 121, 993-1004.
12. Bouwmeester, T., Kim, S.-H., Sasai, Y., Lu, B. and De Robertis, E. M. (1996). Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature 382, 595-601.
13. Candia, A. H., Hu, J., Crosby, J., Lalley, P. A., Noden, D., Nadeau, J. H. and Wright, C. V. E. (1992). Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development 116, 1123-1136.
14. Chen, W. S., Manova, K., Weinstein, D. C., Duncan, S. A., Plump, A. S., Prezioso, V. R., Bachvarova, R. F. and Darnell, J. E., Jr. (1994). Disruption of the HNF-4 gene, expressed in visceral endoderm. leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev. 8, 2466-2477.
15. Cohen, S. and Jurgens, G. (1991). Drosophila headlines. Trends Genet. 7, 267-272.
16. Collignon, J., Sockanathan, S., Hacker, A., Cohen-Tannoudji, M., Norris, D., Rastan, S., Stevanovic, M., Goodfellow, P. N. and Lovell-Badge, R. (1996). A comparison of properties of Sox-3 with Sry and two related genes, Sox-1 and Sax-2. Development 122, 509-520.
17. Conlon, R. A. and Herrmann, B. G. (1993). Detection of messenger RNA by in situ hybridization to postimplantation embryo whole mounts. Methods Enzymol. 225, 373-383.
18. Danielian P. S. and McMahon A. P. (1996). Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature 383, 332-334.
19. Davis, C. A. and Joyner, A. L. (1988). Expression patterns of the homeobox-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development. Genes Dev. 2, 1736-1744.
20. Davis, C. A., Holmyard, D. P., Millen, K. J. and Joyner, A. L. (1991). Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum. Development 111, 287-298.
21. Dierich, A. and Dollé, P. (1997). Gene targeting in embryonic stem cells. In Methods in Developmental Toxicology and Biology, pp111-123. Oxford: Bluckwell Science.
22. -/- embryos. Development 124, 279-287.
23. Finkelstein, R. and Perrimon, N. (1991). The molecular genetics of head development in Drosophila melanogaster. Development 112, 899-912.
24. Friedrich, G. and Soriano, P. (1991). Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev, 5, 1513-1523.
25. Fung, Y. K., Shackleford, G. M., Brown, A. M. and Sanders, G. S. (1985). Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene. Mol. Cell Biol. 5, 3337-3344.
26. Gan, L., Mao, C.-A., Wikramanayake, A., Angerer, L. M., Angerer, R. C. and Klein, W. H. (1995). An orthodenticle-related protein from Strongylocentrotus purpuratus. Dev. Biol. 167, 517-528.
27. Hemmati-Brivanlou, A., Kelly, O. G. and Melton, D. A. (1994). Follistatin, an antagonist of activin is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295.
28. Hermesz, E., Mackem, S. and Mahon, K. A. (1996). Rpx: a novel anterior- restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo. Development 122, 41-52.
29. Hogan, B., Beddington, R., Constantini, F., and Lacy, E. (1994). Manipulating the Mouse Embryo: A Laboratory Manual, New York: Cold Spring Harbor.
30. Jollie, W. P. (1990). Development, morphology, and function of the yolk-sac placenta of laboratory rodents. Teratology 41, 361-381.
31. Kaestner, K. H., Monaghan, A. P., Kern, H., Ang, S.-L., Weitz, S., Lichter, P. and Schutz, G. (1995). The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization. J. Biol. Chem. 270, 30029-30035.
32. Kaufman, M. H. (1992). The Atlas of Mouse Development. New York: Academic Press.
33. Lemaire, P. and Kodjabachian, L. (1996). The verterbrate organizer: structure and molecules. Trends Genet. 12, 525-530.
34. Li, Y., Allend, M. L., Finkelstein, R. and Weinberg, E. S. (1994). Expression of zebrafish orthodenticle-related genes in the embryonic brain. MOD 48, 229-244.
35. Matsuo, I., Kuratani, S., Kimura, C., Takeda, N. and Aizawa, S. (1995). Mouse Otx2 functions in the formation and patterning of rostral head. Genes Dev. 9, 2646-2658.
36. - mice results from stepwise deletion of engrailed expressing cells by 9.5 days postcoitum. Cell 69, 581-595.
37. Mercier, P., Simeone, A., Coteli, F. and Boncinelli, E. (1995). Expression pattern of the two otx genes suggests a role in specifying anterior body structures in zebrafish. Int. J. Dev. Biol. 39, 559-573.
38. Millet, S., Bloch-Gallego, E., Simeone, A. and Alvarado-Mallart, R. M. (1996). The caudal limit of Otx2 gene expression as a marker of the midbrain/hindbrain boundary: a study using in situ hybridization and chick/quail homotopic grafts. Development 122, 3785-3797.
39. Nagy, A., Rossant, J., Nagy, R., Abramov-Neuely, W. and Roder. (1993). Viable cell culture-derived mice from early passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428.
40. Nornes, H. O., Dressler, G. R., Knapik, E. W., Deutsch, U. and Gruss, P. (1990). Spatially and temporally restricted expression of Pax2 during murine neurogenesis. Development 109, 797-809.
41. Oliver, G., Mailhos, A., Wehr, R., Copeland, N. G., Jenkins, N. A. and Gruss, P. (1995). Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development 121, 4045-4055.
42. Pannese, M., Polo, C., Andreazzoli, M., Vignali, R., Kablar, B., Barsacchi, G. and Boncinelli, E. (1995). The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions. Development 121, 707-720.
43. Robertson, E.J. (1987). Embryo-derived stem cell lines. In Teratocarcinomas and Embryonic Stem cells: a Practical Approach (ed E. J. Robertson), pp.71-112. Oxford: IRL Press.
44. Rowitch, D. H. and McMahon, A. P. (1995). Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech. Dev. 52, 3-8.
45. Sasai, Y., Lu, B., Steinbesser, H., Geissert, D., Gont, L. K., and De Robertis, E. M. (1995). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.
46. Shawlot, W. and Behringer, R. R. (1995). Requirement for Lim1 in head- organizer function. Nature 374, 425-430.
47. Simeone, A. Gulisano, M., Acampora, D., Stornaiuolo, A., Rambaldi, M. and Boncinelli, E. (1992). Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 11, 2541-2550.
48. Simeone, A., Acampora, D., Mallamaci, A., Stornaiuolo, A., D'Apice. M. R., Nigro. V. and Boncinelli, E. (1993). A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J. 12, 2735-2747.
49. Smith, W. C. and Harland, R. M. (1992). Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70, 829-840.
50. Spyropoulus, D. D. and Capecchi, M. R. (1994). Targeted disruption of the even-skipped genes, evx1, causes early postimplantation lethality of the mouse conceptus. Genes Dev. 8, 1949-1961.
51. te Riele, H., Robanus Maandag, E., Clarke, A., Hooper, M. and Berns, A. (1990). Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells. Nature 348, 649-651.
52. Thomas, P. and Beddington, R. (1996). Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo. Curr. Biol. 6, 1487-1496.
53. Varlet, I., Collignon, J. and Robertson, E. J. (1997). nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development 124, 1033-1044.
54. Wilkinson, D. G., Bhatt, S., Cook, M., Boncinelli, E. and Krumlauf, R. (1989). Segmental expression of Hox-2 homeobox genes in the developing mouse hindbrain. Nature 341, 405-409.