A combined analysis of genomic and primary protein structure defines the phylogenetic relationship of new members of the T-box family

Genomics

Volumn 48, Issue 1, 1998, Pages 24-33

  Wattler, Sigrid ^a,c   Russ, Andreas ^b   Evans, Martin ^b   Nehls, Michael ^a,c  

^a IPF PHARMACEUTICALS GMBH   (Germany)

^b WELLCOME CRC INSTITUTE   (United Kingdom)

^c LEXICON PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GENE PRODUCT;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; DNA BINDING; DNA SEQUENCE; DROSOPHILA; EXON; GENOME; HUMAN; HUMAN CELL; INTRON; MODEL; MOUSE; MULTIGENE FAMILY; NEMATODE; NONHUMAN; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN STRUCTURE;

EID: 0031889965     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1997.5150     Document Type: Article

References (38)

1. Agulnik S. I., Garvey N., Hancock S., Ruvinsky I., Chapman D. L., Agulnik I., Bollag R., Papaioannou V., Silver L. M. Evolution of mouse T-box genes by tandem duplication and cluster dispersion. Genetics. 25:1996;249-254.
2. Bamshad M., Lin R. C., Law D. J., Watkins W. S., Krakowiak P. A., Moore M. E., Franceschini P., Lala R., Holmes L. B., Gebuhr T. C., Bruneau B. G., Schinzel A., Seidman J. G., Seidman C. E., Jorde L. B. Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. Nature Genet. 16:1997;311-315.
3. Basson C. T., Bachinsky D. R., Lin R. C., Levi T., Elkins J. A., Soults J., Graycel D., Kroumpouzou E., Traill T. A., Leblanc-Straceski J., Renault B., Kucherlapati R., Seidman J. G., Seidman C. E. Mutations in human cause limb and cardiac malformations in Holt-Oram syndrome. Nature Genet. 15:1997;30-35.
4. Bollag R. J., Siegfried Z., Cebra-Thomas J. A., Garvey N., Davison E. M., Silver L. M. An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus. Nature Genet. 7:1994;383-389.
5. Bulfone A., Smiga S. M., Shimamura K., Peterson A., Puelles L., Rubenstein J. L. R. T-brain-1: A homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. Neuron. 15:1995;63-78.
6. Chapman D. L., Agulnik I., Hancock S., Silver L. M., Papaioannou V. E. Tbx6, a mouse T-box gene implicated in paraxial mesoderm formation at gastrulation. Dev. Biol. 180:1996a;534-542.
7. Chapman D. L., Garvey N., Hancock S., Alexiou M., Agulnik S. I., Gibson-Brown J. J., Cebra-Thomas J., Bollag R. J., Silver L. M., Papaioannou V. E. Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Dev. Dyn. 206:1996b;379-390.
8. Cunliffe V., Smith J. C. Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue. Nature. 358:1992;427-430.
9. Dobrovolskaia-Zavadskaia N. Sur la mortification spontanee de la queue chez la souris nouveau-nee et sur l'existence d'un caractere hereditaire 'non viable.'. C. R. Hebd. Seances Soc. Biol. 97:1927;114-116.
10. Gibson-Brown J. J., Agulnik S. I., Chapman D. L., Alexiou M., Garvey N., Silver L. M., Papaioannou V. E. Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity. Mech. Dev. 56:1996;93-101.
11. Halpern M. E., Ho R. K., Walker C., Kimmel C. B. Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation. Cell. 75:1993;99-111.
12. Hein J. J. Unified approach to alignment and phylogenies. Methods Enzymol. 183:1990;626-645.
13. Herrmann B. G. Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos. Development. 113:1991;913-917.
14. Herrmann B. G. Action of the Brachyury gene in mouse embryogenesis. Ciba Found. Symp. 165:1992;78-86.
15. Herrmann B. G., Kispert A. The T genes in embryogenesis. Trends Genet. 10:1994;280-286.
16. Herrmann B. G., Labeit S., Poustka A., King T. R., Lehrach H. Cloning of the T gene required in mesoderm formation in the mouse. Nature. 343:1990;617-622.
17. Holland P. W. H., Koschorz B., Holland L. Z., Herrmann B. G. Conservation of Brachyury (T) genes in amphioxus and vertebrates: Developmental and evolutionary implications. Development. 121:1995;4283-4291.
18. Hug B., Walter V., Grunwald D. J. Tbx6, a Brachyury-related gene expressed by ventral mesendodermal precursors in the zebrafish embryo. Dev. Biol. 183:1997;61-73.
19. Kispert A., Herrmann B. G. The Brachyury gene encodes a novel DNA binding protein. EMBO J. 12:1993;3211-3220.
20. Kispert A., Herrmann B. G. Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos. Dev. Biol. 161:1994;179-193.
21. Kispert A., Herrmann B. G., Leptin M., Reuter R. Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta. Genes Dev. 8:1994;2135-2150.
22. Kispert A., Koschorz B., Herrmann B. G. The T protein encoded by Brachyury is a tissue-specific transcription factor. EMBO J. 14:1995a;4763-4772.
23. Kispert A., Ortner H., Cooke J., Herrmann B. G. The chick Brachyury gene: Developmental expression pattern and response to axial induction by localized activin. Dev. Biol. 168:1995b;406-415.
24. Knezevic V., De Santo R., Mackem S. Two novel chick T-box genes related to mouse Brachyury are expressed in different, non overlapping mesodermal domains during gastrulation. Development. 124:1997;411-419.
25. Lustig K. D., Kroll K. L., Sun E. E., Kirschner M. W. Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation. Development. 122:1996;4001-4012.
26. Matysiak-Scholze U., Nehls M. The structural integrity of RORα isoforms is mutated instaggerer. Genomics. 43:1997;78-84.
27. Pflugfelder G. O., Roth H., Poeck B. A homology domain shared betweenDrosophila. Biochem. Biophys. Res. Commun. 186:1992;918-925.
28. Ryan K., Garrett N., Mitchell A., Gurdon J. B. Eomesodermin, a key early gene in Xenopus mesoderm differentiation. Cell. 87:1996;989-1000.
29. Schulte-Merker S., Ho R. K., Herrmann B. G., Nüsslein-Volhard C. The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. Development. 116:1992;1021-1032.
30. Schulte-Merker S., van Eeden F. J., Halpern M. E., Kimmel C. B., Nüsslein-Volhard C. no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development. 120:1994;1009-1015.
31. Simon H.-G., Kittappa R., Khan P. A., Tsilfidis C., Liversage R. A., Oppenheimer S. A novel family of T-box genes in urodele amphibian limb development and regeneration: Candidate genes involved in vertebrate forelimb/hindlimb patterning. Development. 124:1997;1355-1366.
32. Smith J. C., Price B. M., Green J. B., Weigel D., Herrmann B. G. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm-induction. Cell. 67:1991;79-87.
33. Stoltzfus A., Logsdon M. J. Jr., Palmer J. D., Ford Doolittle W. Intron "sliding" and the diversity of intron positions. Proc. Natl. Acad. Sci. USA. 94:1997;10739-10744.
34. Strahle U., Blader P., Henrique D., Ingham P. W. Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos. Genes Dev. 7:1993;1436-1446.
35. Wilkinson D. G., Bhatt S., Herrmann B. G. Expression pattern of the mouse T gene and its role in mesoderm formation. Nature. 343:1990;657-659.
36. Wilson V., Rashbass P., Beddington R. S. Chimeric analysis of T (Brachyury) gene function. Development. 117:1993;1321-1331.
37. Yasuo H., Satoh N. Function of vertebrate T gene. Nature. 364:1993;582-583.
38. Yi Li Q., Newbury-Ecob R. A., Terrett J. A., Wilson D. I., Curtis A. R. J., Ho Yi C., Gebuhr T., Bullen P. J., Robson S. C., Strachan T., Bonnet D., Lyonnet S., Young I. D., Raeburn J. A., Buckler A. J., Law D. J., Brook J. D. Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nature Genet. 15:1997;21-29.