Activation of JNK/SAPK in primary glial cultures: II. Differential activation of kinase isoforms corresponds to their differential expression

Neurochemical Research

Volumn 23, Issue 2, 1998, Pages 219-225

  Zhang, P ^a   Hogan, E L ^a   Bhat, N R ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Astrocytes; c Jun N terminal kinase; Microglia; Oligodendrocytes; TNF

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 1; ISOENZYME; LYMPHOTOXIN; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GLIA CELL; MACROGLIA; MICROGLIA; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; ENZYME ACTIVATION; ISOENZYMES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROGLIA; PROTEIN KINASES; RATS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0031885806     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022489127107     Document Type: Article

References (34)

1. Cano, E., and Mahadevan, L. C. 1995. Parallel signal processing among mammalian MAPKs. Trends Biochem. Sci. 20:117-122.
2. Kyriakis, J. M., and Avruch, J. 1996. Sounding the alarm: Protein kinase cascades activated by stress and inflammation. J. Biol. Chem. 271:24313-24316.
3. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J., and Woodgett, J. R. 1994. The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369:156-160.
4. Gupta, S., Barrett, T., Whitmarsh, A. J., Cavanagh, J., Sluss, H. K., Derijard, B., and Davis, R., 1996. Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J. 15: 2760-2770.
5. Hill, C. S., and Treisman, R. 1995. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80:199-211.
6. Karin, M. 1995. The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 270:16483-16486.
7. Barna, B. P., Estes, M. L., Jacobs, B. S., Hudson, S., and Ransohoff, R. M. 1990. Human strocytes proliferate in response to tumor necrosis factor alpha. J. Neuro-immunol. 30:239-243.
8. Giulian, D., Woodward, J., Young, D. G., Krebs, J. F., Lachman, L. B. 1988. Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization. J. Neurosci. 8:2485-2490.
9. Yong, V. W., Moumdijian, R., Yong, F. P., Ruijs, T. G. C., Freedman, M. S., Cashman, N., and Antel, J. P. 1991. Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo. Proc. Natl. Acad. Sci. USA. 88:7016-7020.
10. D'Souza, S., Alinauskas, K., McCrea, E., Goodyear, C., and Antel, J. P. 1995. Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury. J. Neurosci. 15:7293-7230.
11. Raine, C. S. 1995. Multiple sclerosis: TNF revisited, with promise. Nature Med. 1:211-214.
12. Vartanian, T., Li, Y., Zhao, M., and Stefansson, K. 1995. Interferon-γ induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. Mol. Med. 1:732-743.
13. Zhang, P., Miller, B. S., Rosenzweig, S. A., and Bhat, N. R. 1996. Activation of c-Jun N-terminal kinase/stress-activated protein kinase in primary glial cultures. J. Neurosci. Res. 46:114-121.
14. Perry, V. H., Andersson, P-B., and Gordon, S. 1993. Macrophages and inflammation in the central nervous system. Trends Neurosci. 16:268-273.
15. Streit, W. J., and Kincaid-Colton, C. A. 1995. The brain's immune system. Sci. Am. 273:54-61.
16. Wekerle, H. 1995. Antigen presentation by central nervous system glia. Pages 685-699, In Kettenman, H., and Ransom, B. R. (eds.), Neuroglia. Oxford Univ Press.
17. Dickson, D. W., Mattiace, L. A., Kure, K., Hutchins, K., Lyman, W. D., Brosnan, C. F. 1991. Biology of disease: Microglia in human disease, with an emphasis on acquired immune deficiency syndrome. Lab. Invest. 64:135-156.
18. Giulian, D. 1992. Microglia and disease of the nervous system. Curr. Topics Neurol. 12:23-54.
19. Kruetzberg, G. W. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19:312-318.
20. Merrill, J. E., and Benveniste, E. N. 1996. Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci. 19: 331-338.
21. Sweet, M. J., and Hume, D. A. 1996. Endotoxin signal transduction in macrophages. J. Leuk. Biol. 60:8-26.
22. Ulevitch, R. J., and Tobias, P. S. 1995. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Ann. Rev. Immunol. 13:437-457.
23. Bhat, N. R., Hauser, K. F., and Kindy, M. S. 1992. Cell proliferation and proto-oncogene induction in oligodendroglial progenitors. J. Neurosci. Res. 32:340-349.
24. Bhat, N. R., Zhang, P., and Bhat, A. N. 1995. Expression of MARCKS in oligodendrocytes is developmentally regulated. Dev. Neurosci. 17:256-263.
25. Bhat, N. R., and Zhang, P. 1994. Inhibitors of N-linked oligosaccharide processing glucosidases interfere with oligodendrocyte differentiation in culture. J. Neurosci. Res. 39:1-10.
26. Hibi, M., Lin, A., Smeal, T., Minden, A., and Karin, M. 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7:2135-2148.
27. 2-terminal kinase/stress-activated protein kinase by insulin. Biochemistry 35:8769-8775.
28. Raff, M. C., Miller, R. H., and Noble, M. 1983. A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303:390-396.
29. Bruce, A. J., Boling, W., Kindy, M. S., Peschon, J., Kraemer, P. J., Carpenter, M. K., Holtsberg, F. W., and Mattson, M. P. 1996. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nature Med. 7:788-794.
30. Hambleton, J., Weinstein, S. L., Lem, L., and DeFranco, A. L. 1996. Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. Proc. Natl. Acad. Sci. USA. 93:2774-2778.
31. Lee, J. C., and Young, P. R. 1996. Role of CSBP/p38/RK. stress-response kinase in LPS and cytokine signaling mechanisms. J. Leuk. Biol. 59:152-157.
32. Becher, B., Federowicz, V., and Antel, J. 1996. Regulation of CD14 expression on human adult central nervous system-derived microglia. J. Neurosci. Res. 45:375-38.
33. Galea, E., Reis, D. J., Fox, E. S., Xu, H., and Feinstein, D. L. 1996. CD14 mediates endotoxin induction of nitric oxide synthase in cultured brain glial cells. J. Neuro-immunol. 64:19-28.
34. Bhat, N .R., Lee, J. C., and Zhang, P. 1997. MAP kinase cascades and microglial activation. J. Neurochem. 69 (suppl.) S206D.