TGF-βs stimulate cell proliferation via an autocrine production of FGF-2 in corneal stromal fibroblasts

Current Eye Research

Volumn 17, Issue 3, 1998, Pages 286-293

  Kay, EunDuck P ^a,b,c   Lee, Moon Shin ^a   Seong, Gong Je ^a   Lee, Young Ghee ^a  

^a Yonsei University College of Medicine   (South Korea)

^b DOHENY EYE INSTITUTE   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Corneal stromal fibroblast; Fibroblast growth factor; p27; Rabbit; Transforming growth factor; Transforming growth factor receptor

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BETA GLUCAN; CELL DNA; FIBROBLAST GROWTH FACTOR 2; NEUTRALIZING ANTIBODY; PROTEIN P27; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CORNEA STROMA; CULTURE MEDIUM; DNA SYNTHESIS; DOSE RESPONSE; FIBROBLAST; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOLECULAR SIZE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL COUNT; CELL CYCLE PROTEINS; CELL DIVISION; CELLS, CULTURED; CORNEAL STROMA; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; IMMUNOENZYME TECHNIQUES; MICROTUBULE-ASSOCIATED PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; RABBITS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 0031884834     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.17.3.286.5212     Document Type: Article

References (32)

1. Massagué, J. (1990) The transforming growth factor-β family. Annu. Rev. Cell. Biol. 6, 597-641.
2. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F. and Massagué, J. (1994) Mechanism of activation of the TGF-β receptor. Nature, 370, 341-347.
3. Sporn, M. B. and Roberts, A. B. (1992) Transforming growth factor β: recent progress and new challenges. J. Cell Biol. 119, 1017-1021.
4. Ewen, M. E., Sluss, H. K., Whitehouse, L. L. and Livingston, D. M. (1993) TGF-β inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell, 74, 1009-1020.
5. Koff, A., Ohtsuki, M., Polyak, K., Roberts, J. M. and Massagué, J. (1993) Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase of TGF-β. Science, 260, 536-539.
6. Polyak, K., Kato, J. Y., Solomon, M. J., Sherr, C. J., Massagué, J., Roberts, J. M. and Koff, A. (1994) p27kip1, a cyclin-cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8, 9-22.
7. Silberstein, G. B. and Daniel, C. W. (1987) Reversible inhibition of mammary gland growth by transforming growth factor-β. Science, 247, 291-293.
8. Roberts, A. B. and Sporn, M. B. (1990) The transforming growth factor-betas. In Peptide Growth Factors and Their Receptors: Handbook of Experimental Pharmacology, Vol. 95 (Eds. Sporn, M. B. and Roberts, A. B.). Pp. 419-472. Springer-Verlag, Heidelberg.
9. Soma, Y. and Grotendorst, G. R. (1989) TGF-β stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF-related peptides. J. Cell. Physiol. 140, 246-253.
10. Majack, R. A., Majesky, M. W. and Goodman, L. V. (1990) Role of PDGF-A expression in the control of vascular smooth muscle cell growth by transforming growth factor-β. J. Cell Biol. 111, 239-247.
11. de Larco, J. E. and Todaro, G. J. (1978) Growth factors from murine sarcoma virus-transformed cells (epidermal growth factor/polypeptide hormones/cell transformation/ radioreceptor assays). Proc. Natl. Acad. Sci. USA, 75, 4001-4005.
12. Plouët, J. and Gospodarowicz, D. (1989) Transforming growth factor β-1 positively modulates the bioactivity of fibroblast growth factor on corneal endothelial cells. J. Cell. Physiol. 141, 392-399.
13. Kimelman, D. and Kirschner, M. (1987) Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in early Xenopus embryo. Cell, 51, 869-877.
14. Massagué, J. (1992) Receptors for the TGF-β family. Cell, 69, 1067-1070.
15. Miyazono, K., Ichijo, H. and Heldin, C.-H. (1993) Transforming growth factor-β: latent forms, binding proteins and receptors. Growth Factors, 8, 11-22.
16. López-Casillas, F., Wrana, J. L. and Massagué, J. (1993) Betaglycan presents ligand to the TGF-β signaling receptor. Cell, 73, 1435-1444.
17. Kay, E. P., Smith, R. E. and Nimni, M. E. (1985) Type I collagen synthesis by corneal endothelial cells modulated by polymorphonuclear leukocytes. J. Biol. Chem. 260, 5139-5146.
18. Gu, X., Seong, G. J., Lee, Y. G. and Kay, E. P. (1996) Fibroblast growth factor 2 uses distinct signaling pathways for cell proliferation and cell shape changes in corneal endothelial cells. Invest. Ophthalmol. Vis. Sci. 37, 2326-2334.
19. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248, 254.
20. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
21. 3H]-adenine metabolism and radiation damage during in vitro development of the kidney. J. Histochem. Cytochem. 40, 1173-1182.
22. Gentry, L. E. and Nash, B. W. (1990) The pro-domain of pre-pro-transforming growth factor β1 when independently expressed is a functional binding protein for the mature growth factor. Biochemistry, 29, 6851-6857.
23. Lyons, R. M., Keski-Oja, J. and Moses, H. L. (1988) Proteolytic activation of latent transforming growth factor-β from fibroblast-conditioned medium. J. Cell. Biol. 106, 1659-1665.
24. Attisano, L., Wrana, J. L., Lopez-Casillas, F. and Massague, J. (1994) TGF-β receptors and actins. Biochim. Biophys. Acta, 1222, 71-80.
25. Wang, X.-F., Lin, H. Y., Ng-Eaton, E., Downward, J., Lodish, H. F. and Weinberg, R. A. (1991) Expression cloning and characterization of the TGF-type III receptor. Cell, 67, 797-805.
26. Ravitz, M. J., Yan, S., Dolce, C., Kinniburgh, A. J. and Wenner, C. E. (1996) Differential regulation of p27 and cyclin D1 by TGF-β and EGF in C3H 10T1/2 mouse fibroblasts. J. Cell. Physiol. 168, 510-520.
27. Starksen, N. F., Harsh, G. R., Gibbs, V. C. and Williams, L. T. (1987) Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells. J. Biol. Chem. 262, 14381-14384.
28. Leof, E. B., Proper, J. A., Goustin, A. S., Shipley, G. D., DiCorleto, P. E. and Moses, H. L. (1986) Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor β: a proposed model for indirect mitogenesis involving autocrine activity. Proc. Natl. Acad. Sci. USA, 83, 2453-2457.
29. Jester, J. V., Barry-Lane, P. A., Cavanagh, H. D. and Petroll, W. M. (1996) Induction of β-smooth muscle actin expression and myofibroblast transformation in cultured corneal keratocytes. Cornea, 15, 505-516.
30. Sato, Y., Okada, F., Abe, M., Seguchi, T., Kuwano, M., Sato, S., Furuya, A., Hanai, N. and Tamaoki, T. (1993) The mechanism for the activation of latent TGF-β during co-culture of endothelial cells and smooth muscle cells: cell-type specific targeting of latent TGF-β to smooth muscle cells. J. Cell. Biol. 123, 1249-1254.
31. Purchio, A. F., Cooper, J. A., Brunner, A. M., Lioubin, M. N., Gentry, L. E., Kovacina, K. S., Roth, R. A. and Marquard, H. (1988) Identification of mannose-6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor β1 precursor. J. Biol. Chem. 263, 14211-14215.
32. Jirtle, R. L., Haag, J. D., Ariazi, E. A. and Gould, M. N. (1993) Increased mannose-6-phosphate/insulin-like growth factor II receptor and transforming growth factor β1 levels during monoterpene-induced regression of mammary tumors. Cancer Res. 53, 3849-3852.