-
1
-
-
0023221419
-
A small catalytic oligoribonucleotide
-
Uhlenbeck, O.C. (1987) A small catalytic oligoribonucleotide. Nature 328, 596-600
-
(1987)
Nature
, vol.328
, pp. 596-600
-
-
Uhlenbeck, O.C.1
-
2
-
-
0024286910
-
Construction of a series of several self-cleaving RNA duplexes using synthetic 21-mers
-
Koizumi, M., Iwai, S., and Ohtsuka, E. (1988) Construction of a series of several self-cleaving RNA duplexes using synthetic 21-mers. FEBS Lett. 228, 228-230
-
(1988)
FEBS Lett.
, vol.228
, pp. 228-230
-
-
Koizumi, M.1
Iwai, S.2
Ohtsuka, E.3
-
3
-
-
0025301934
-
The role of a conserved guanosine residue in the hammerhead-type RNA enzyme
-
Odai, O., Hiroaki, H., Sakata, T., Tanaka, T., and Uesugi, S. (1990) The role of a conserved guanosine residue in the hammerhead-type RNA enzyme. FEBS Lett. 267, 150-152
-
(1990)
FEBS Lett.
, vol.267
, pp. 150-152
-
-
Odai, O.1
Hiroaki, H.2
Sakata, T.3
Tanaka, T.4
Uesugi, S.5
-
4
-
-
0026771509
-
Numbering system for the hammerhead
-
Hertel, K.J., Pardi, A., Uhlenbeck, O.C., Koizumi, M., Ohtsuka, E., Uesugi, S., Cedergren, R., Eckstein, F., Gerlach, W.L., Hodgson, R., and Symons, R.H. (1992) Numbering system for the hammerhead. Nucleic Acids Res. 20, 3252
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 3252
-
-
Hertel, K.J.1
Pardi, A.2
Uhlenbeck, O.C.3
Koizumi, M.4
Ohtsuka, E.5
Uesugi, S.6
Cedergren, R.7
Eckstein, F.8
Gerlach, W.L.9
Hodgson, R.10
Symons, R.H.11
-
5
-
-
0026485636
-
7-nitrogens for efficient cleavage by a hammerhead ribozyme. A model for magnesium binding
-
7-nitrogens for efficient cleavage by a hammerhead ribozyme. A model for magnesium binding. Biochemistry 31, 10941-10949
-
(1992)
Biochemistry
, vol.31
, pp. 10941-10949
-
-
Fu, D.J.1
McLaughlin, L.W.2
-
6
-
-
0026532114
-
Importance of specific purine amino and hydroxyl groups for efficient cleavage by a hammerhead ribozyme
-
Fu, D.J. and McLaughlin, L.W. (1992) Importance of specific purine amino and hydroxyl groups for efficient cleavage by a hammerhead ribozyme. Proc. Natl. Acad. Sci. USA 89, 3985-3989
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 3985-3989
-
-
Fu, D.J.1
McLaughlin, L.W.2
-
7
-
-
0027484903
-
7-nitrogens and purine amino groups for efficient cleavage by a hammerhead ribozyme
-
7-nitrogens and purine amino groups for efficient cleavage by a hammerhead ribozyme. Biochemistry 32, 10629-10637
-
(1993)
Biochemistry
, vol.32
, pp. 10629-10637
-
-
Fu, D.J.1
Rajur, S.B.2
McLaughlin, L.W.3
-
8
-
-
0026563846
-
The role of the exocyclic amino groups of conserved purines in hammerhead ribozyme cleavage
-
Slim, G. and Gait, M.J. (1992) The role of the exocyclic amino groups of conserved purines in hammerhead ribozyme cleavage. Biochem. Biophys. Res. Commun. 183, 605-609
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.183
, pp. 605-609
-
-
Slim, G.1
Gait, M.J.2
-
9
-
-
0027426257
-
Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity
-
Tuschl, T., Ng, M.M.P., Pieken, W., Benseler, F., and Eckstein, F. (1993) Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity. Biochemistry 32, 11658-11668
-
(1993)
Biochemistry
, vol.32
, pp. 11658-11668
-
-
Tuschl, T.1
Ng, M.M.P.2
Pieken, W.3
Benseler, F.4
Eckstein, F.5
-
10
-
-
0025264597
-
Mixed deoxyribo- And ribooligonucleotides with catalytic activity
-
Perreault, J.P., Wu, T., Cousineau, B., Ogilivie, K.K., and Cedergren, R. (1990) Mixed deoxyribo- and ribooligonucleotides with catalytic activity. Nature 344, 565-567
-
(1990)
Nature
, vol.344
, pp. 565-567
-
-
Perreault, J.P.1
Wu, T.2
Cousineau, B.3
Ogilivie, K.K.4
Cedergren, R.5
-
11
-
-
0025762699
-
Relationship between 2′-hydroxyls and magnesium binding in the hammerhead RNA domain: A model for ribozyme catalysis
-
Perreault, J.P., Labuda, D., Usman, N., Yang, J.H., and Cedergren, R. (1991) Relationship between 2′-hydroxyls and magnesium binding in the hammerhead RNA domain: A model for ribozyme catalysis. Biochemistry 30, 4020-4025
-
(1991)
Biochemistry
, vol.30
, pp. 4020-4025
-
-
Perreault, J.P.1
Labuda, D.2
Usman, N.3
Yang, J.H.4
Cedergren, R.5
-
12
-
-
0026558930
-
Function of specific 2′-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2′ modification
-
Williams, D.M., Pieken, W.A., and Eckstein, F. (1992) Function of specific 2′-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2′ modification. Proc. Natl. Acad. Sci. USA 89, 918-921
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 918-921
-
-
Williams, D.M.1
Pieken, W.A.2
Eckstein, F.3
-
13
-
-
0026711027
-
Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain
-
Yang, J.H., Usman, N., Chartrand, P., and Cedergren, R. (1992) Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain. Biochemistry 31, 5005-5009
-
(1992)
Biochemistry
, vol.31
, pp. 5005-5009
-
-
Yang, J.H.1
Usman, N.2
Chartrand, P.3
Cedergren, R.4
-
14
-
-
0026040878
-
Study of a hammerhead ribozyme containing 2′-modified adenosine residues
-
Olsen, D.B., Benseler, F., Aurup, H., Pieken, W.A., and Eckstein, F. (1991) Study of a hammerhead ribozyme containing 2′-modified adenosine residues. Biochemistry 30, 9735-9741
-
(1991)
Biochemistry
, vol.30
, pp. 9735-9741
-
-
Olsen, D.B.1
Benseler, F.2
Aurup, H.3
Pieken, W.A.4
Eckstein, F.5
-
15
-
-
0025148422
-
Identification of a non-junction phosphodiester that influences an autolytic processing reaction of RNA
-
Buzayan, J.M., Van Tol, H., Feldstein, P.A., and Bruening, G. (1990) Identification of a non-junction phosphodiester that influences an autolytic processing reaction of RNA. Nucleic Acids Res. 18, 4447-4451
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 4447-4451
-
-
Buzayan, J.M.1
Van Tol, H.2
Feldstein, P.A.3
Bruening, G.4
-
16
-
-
0025130635
-
Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction
-
Ruffner, D.E. and Uhlenbeck, O.C. (1990) Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction. Nucleic Acids Res. 18, 6025-6029
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 6025-6029
-
-
Ruffner, D.E.1
Uhlenbeck, O.C.2
-
17
-
-
9044232886
-
Hammerhead-type RNA enzyme and its derivatives which consist of three RNA oligomer strands
-
Sarma, R.H. and Sarma, M.H., eds. Adenine Press, Schenectady
-
Uesugi, S., Odai, O., Kodama, H., Hiroaki, H., Sakata, T., and Tanaka, T. (1992) Hammerhead-type RNA enzyme and its derivatives which consist of three RNA oligomer strands in Structure and Function (Sarma, R.H. and Sarma, M.H., eds.) Vol. 2, pp. 143-158, Adenine Press, Schenectady
-
(1992)
Structure and Function
, vol.2
, pp. 143-158
-
-
Uesugi, S.1
Odai, O.2
Kodama, H.3
Hiroaki, H.4
Sakata, T.5
Tanaka, T.6
-
18
-
-
0026027594
-
Nuclear magnetic resonance studies of the hammerhead ribozyme domain: Secondary structure formation and magnesium ion dependence
-
Heus, H.A. and Pardi, A. (1991) Nuclear magnetic resonance studies of the hammerhead ribozyme domain: Secondary structure formation and magnesium ion dependence. J. Mol. Biol. 217, 113-124
-
(1991)
J. Mol. Biol.
, vol.217
, pp. 113-124
-
-
Heus, H.A.1
Pardi, A.2
-
19
-
-
0025075436
-
Synthesis and NMR study of ribooligonucleotides forming a hammerhead-type RNA enzyme system
-
Odai, O., Kodama, H., Hiroaki, H., Sakata, T., Tanaka, T., and Uesugi, S. (1990) Synthesis and NMR study of ribooligonucleotides forming a hammerhead-type RNA enzyme system. Nucleic Acids Res. 18, 5955-5960
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 5955-5960
-
-
Odai, O.1
Kodama, H.2
Hiroaki, H.3
Sakata, T.4
Tanaka, T.5
Uesugi, S.6
-
20
-
-
0025217237
-
Sequence-dependent structural variations of hammerhead RNA enzymes
-
Heus, H.A., Uhlenbeck, O.C., and Pardi, A. (1990) Sequence-dependent structural variations of hammerhead RNA enzymes. Nucleic Acids Res. 18, 1103-1108
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 1103-1108
-
-
Heus, H.A.1
Uhlenbeck, O.C.2
Pardi, A.3
-
22
-
-
0028234371
-
Probing the hammerhead ribozyme structure with ribonucleases
-
Hodgson, R.A.J., Shirley, N.J., and Symons, R.H. (1994) Probing the hammerhead ribozyme structure with ribonucleases. Nucleic Acids Res. 22, 1620-1625
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 1620-1625
-
-
Hodgson, R.A.J.1
Shirley, N.J.2
Symons, R.H.3
-
23
-
-
0028063567
-
Three-dimensional structure of a hammerhead ribozyme
-
Pley, H.W., Flaherty, K.M., and Mckay, D.B. (1994) Three-dimensional structure of a hammerhead ribozyme. Nature 372, 68-74
-
(1994)
Nature
, vol.372
, pp. 68-74
-
-
Pley, H.W.1
Flaherty, K.M.2
Mckay, D.B.3
-
24
-
-
0029073091
-
The crystal structure of an all-RNA hammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage
-
Scott, W.G., Finch, J.T., and Klug, A. (1995) The crystal structure of an all-RNA hammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage. Cell 81, 991-1002
-
(1995)
Cell
, vol.81
, pp. 991-1002
-
-
Scott, W.G.1
Finch, J.T.2
Klug, A.3
-
25
-
-
0026686191
-
Minimal sequence requirements for ribozyme activity
-
McCall, M.J., Hendry, P., and Jennings, P.A. (1992) Minimal sequence requirements for ribozyme activity. Proc. Natl. Acad. Sci. USA 89, 5710-5714
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5710-5714
-
-
McCall, M.J.1
Hendry, P.2
Jennings, P.A.3
-
26
-
-
0027250866
-
Hammerhead ribozymes: Importance of stem-loop II for activity
-
Tuschl, T. and Eckstein, F. (1993) Hammerhead ribozymes: Importance of stem-loop II for activity. Proc. Natl. Acad. Sci. USA 90, 6991-6994
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6991-6994
-
-
Tuschl, T.1
Eckstein, F.2
-
27
-
-
0028339955
-
Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions
-
Long, D.M. and Uhlenbeck, O.C. (1994) Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions. Proc. Natl. Acad. Sci. USA 91, 6977-6981
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6977-6981
-
-
Long, D.M.1
Uhlenbeck, O.C.2
-
28
-
-
14444270690
-
Characterization of a hammerhead ribozyme with deletion of stem II
-
Sakamoto, T., Kim, M., Kurihara, Y., Sasaki, N., Noguchi, T., Katahira, M., and Uesugi, S. (1994) Characterization of a hammerhead ribozyme with deletion of stem II. Nucleic Acids Symp. Ser. No. 31, 189-190
-
(1994)
Nucleic Acids Symp. Ser. No. 31
, vol.31
, pp. 189-190
-
-
Sakamoto, T.1
Kim, M.2
Kurihara, Y.3
Sasaki, N.4
Noguchi, T.5
Katahira, M.6
Uesugi, S.7
-
29
-
-
0027744196
-
Activity of hammerhead ribozymes containing non-nucleotidic linkers
-
Thomson, J.B., Tuschl, T., and Eckstein, F. (1993) Activity of hammerhead ribozymes containing non-nucleotidic linkers. Nucleic Acids Res. 21, 5600-5603
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 5600-5603
-
-
Thomson, J.B.1
Tuschl, T.2
Eckstein, F.3
-
30
-
-
0000476296
-
Hammerhead-like molecules containing non-nucleoside linkers are active RNA catalysts
-
Benseler, F., Fu, D.J., Ludwig, J., and McLaughlin, L.W. (1993) Hammerhead-like molecules containing non-nucleoside linkers are active RNA catalysts. J. Am. Chem. Soc. 115, 8483-8484
-
(1993)
J. Am. Chem. Soc.
, vol.115
, pp. 8483-8484
-
-
Benseler, F.1
Fu, D.J.2
Ludwig, J.3
McLaughlin, L.W.4
-
31
-
-
0000696532
-
Cloning and expression of the gene for bacteriophage T7 RNA polymerase
-
Davanloo, P., Rosenburg, A.H., Dunn, J.J., and Studier, F.W. (1984) Cloning and expression of the gene for bacteriophage T7 RNA polymerase. Proc. Natl. Acad. Sci. USA 81, 2035-2039
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 2035-2039
-
-
Davanloo, P.1
Rosenburg, A.H.2
Dunn, J.J.3
Studier, F.W.4
-
32
-
-
0023651444
-
Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA template
-
Milligan, J.F., Groebe, D.R., Witherell, G.W., and Uhlenbeck, O.C. (1987) Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA template. Nucleic Acids Res. 15, 8783-8798
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 8783-8798
-
-
Milligan, J.F.1
Groebe, D.R.2
Witherell, G.W.3
Uhlenbeck, O.C.4
-
33
-
-
0024819451
-
Enzymatic RNA sequencing
-
Dahlberg, J.E. and Abelson, J.N., eds. Academic Press, New York
-
Kuchino, Y. and Nishimura, S. (1989) Enzymatic RNA sequencing in Methods in Enzymology (Dahlberg, J.E. and Abelson, J.N., eds.) Vol. 180, pp. 154-163, Academic Press, New York
-
(1989)
Methods in Enzymology
, vol.180
, pp. 154-163
-
-
Kuchino, Y.1
Nishimura, S.2
-
34
-
-
0023651145
-
Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides
-
Inoue, H., Hayase, Y., Imura, A., Iwai, S., Miura, K., and Ohtsuka, E. (1987) Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides. Nucleic Acids Res. 15, 6131-6148
-
(1987)
Nucleic Acids Res
, vol.15
, pp. 6131-6148
-
-
Inoue, H.1
Hayase, Y.2
Imura, A.3
Iwai, S.4
Miura, K.5
Ohtsuka, E.6
-
35
-
-
0028239625
-
Properties of a hammerhead-type RNA enzyme system that consists of three RNA oligomer strands
-
Odai, O., Hiroaki, H., Tanaka, T., and Uesugi, S. (1994) Properties of a hammerhead-type RNA enzyme system that consists of three RNA oligomer strands. Nucleosides Nucleotides 13, 1569-1579
-
(1994)
Nucleosides Nucleotides
, vol.13
, pp. 1569-1579
-
-
Odai, O.1
Hiroaki, H.2
Tanaka, T.3
Uesugi, S.4
-
36
-
-
0027732494
-
Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism
-
Dahm, S.C., Derrick, W.B., and Uhlenbeck, O.C. (1993) Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism. Biochemistry 32, 13040-13045
-
(1993)
Biochemistry
, vol.32
, pp. 13040-13045
-
-
Dahm, S.C.1
Derrick, W.B.2
Uhlenbeck, O.C.3
-
37
-
-
0027715889
-
Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions
-
Sawata, S., Shimayama, T., Komiyama, M., Kumar, P.K.R., Nishikawa, S., and Taira, K. (1993) Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions. Nucleic Acids Res. 21, 5656-5660
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 5656-5660
-
-
Sawata, S.1
Shimayama, T.2
Komiyama, M.3
Kumar, P.K.R.4
Nishikawa, S.5
Taira, K.6
-
38
-
-
0025613003
-
Mixed DNA/RNA polymers are cleaved by the hammerhead ribozyme
-
Yang, J.H., Perreault, J.P., Labuda, D., Usman, N., and Cedergren, R. (1990) Mixed DNA/RNA polymers are cleaved by the hammerhead ribozyme. Biochemistry 29, 11156-11160
-
(1990)
Biochemistry
, vol.29
, pp. 11156-11160
-
-
Yang, J.H.1
Perreault, J.P.2
Labuda, D.3
Usman, N.4
Cedergren, R.5
-
39
-
-
0024430869
-
Design of RNA enzymes distinguishing a single base mutation in RNA
-
Koizumi, M., Hayase, Y., Iwai, S., Kamiya, H., Inoue, H., and Ohtsuka, E. (1989) Design of RNA enzymes distinguishing a single base mutation in RNA. Nucleic Acids Res. 17, 7059-7071
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 7059-7071
-
-
Koizumi, M.1
Hayase, Y.2
Iwai, S.3
Kamiya, H.4
Inoue, H.5
Ohtsuka, E.6
-
40
-
-
0015215162
-
Magnesium-induced confermational change in transfer ribonucleic acid as measured by circular dichroism
-
Willick, G.E. and Kay, C.M. (1971) Magnesium-induced confermational change in transfer ribonucleic acid as measured by circular dichroism. Biochemistry 10, 2216-2222
-
(1971)
Biochemistry
, vol.10
, pp. 2216-2222
-
-
Willick, G.E.1
Kay, C.M.2
-
43
-
-
0025963132
-
Visualizing the high order folding of a catalytic RNA molecule
-
Celander, D.W. and Cech, T.R. (1991) Visualizing the high order folding of a catalytic RNA molecule. Science 251, 401-407
-
(1991)
Science
, vol.251
, pp. 401-407
-
-
Celander, D.W.1
Cech, T.R.2
-
44
-
-
0028863805
-
In vitro activity of minimized hammerhead ribozymes
-
Hendry, P., McCall, M.J., Santiago, F.S., and Jennings, P.A. (1995) In vitro activity of minimized hammerhead ribozymes. Nucleic Acids Res. 23, 3922-3927
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 3922-3927
-
-
Hendry, P.1
McCall, M.J.2
Santiago, F.S.3
Jennings, P.A.4
-
45
-
-
0027982498
-
Formation of sheared G:A base pairs in an RNA duplex modeled after ribozymes, as revealed by NMR
-
Katahira, M., Kanagawa, M., Sato, H., Uesugi, S., Fujii, S., Kohno, T., and Maeda, T. (1994) Formation of sheared G:A base pairs in an RNA duplex modeled after ribozymes, as revealed by NMR. Nucleic Acids Res. 22, 2752-2759
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 2752-2759
-
-
Katahira, M.1
Kanagawa, M.2
Sato, H.3
Uesugi, S.4
Fujii, S.5
Kohno, T.6
Maeda, T.7
-
46
-
-
0025998488
-
Role of divalent metal ions in the hammerhead RNA cleavage reaction
-
Dahm, S.C. and Uhlenbeck, O.C. (1991) Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry 30, 9464-9469
-
(1991)
Biochemistry
, vol.30
, pp. 9464-9469
-
-
Dahm, S.C.1
Uhlenbeck, O.C.2
-
47
-
-
0029168512
-
Kinetic evidence based on solvent isotope effects for the nonexistence of a proton-transfer process in reactions catalyzed by a hammerhead ribozyme: Implication to the double-metal-ion mechanism of catalysis
-
Sawata, S., Komiyama, M., and Taira, K. (1995) Kinetic evidence based on solvent isotope effects for the nonexistence of a proton-transfer process in reactions catalyzed by a hammerhead ribozyme: Implication to the double-metal-ion mechanism of catalysis. J. Am. Chem. Soc. 117, 2357-2358
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 2357-2358
-
-
Sawata, S.1
Komiyama, M.2
Taira, K.3
-
48
-
-
0028859512
-
A comparison of the in vitro activity of DNA-armed and all-RNA hammerhead ribozymes
-
Hendry, P. and McCall, M.J. (1995) A comparison of the in vitro activity of DNA-armed and all-RNA hammerhead ribozymes. Nucleic Acids Res. 23, 3928-3936
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 3928-3936
-
-
Hendry, P.1
McCall, M.J.2
|