Correct assembly of human normal adult hemoglobin when expressed in transgenic swine: Chemical, conformational and functional equivalence with the human-derived protein

Protein Engineering

Volumn 11, Issue 7, 1998, Pages 583-588

  Manjula, Belur N ^a   Kumar, Ramesh ^b   Sun, D Philip ^c   Ho, Nancy T ^c   Ho, Chien ^c   Rao, Janardhan M ^a   Malavalli, Ashok ^a   Acharya, A Seetharama ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Nextran   (United States)

^c CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

Human normal adult hemoglobin assembly; Transgenic swine

Indexed keywords

HEMOGLOBIN; HEMOGLOBIN A; RECOMBINANT PROTEIN;

ALLOSTERISM; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; MOLECULAR WEIGHT; NONHUMAN; OXYGEN AFFINITY; PEPTIDE MAPPING; PH; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; SWINE; TRANSGENIC ANIMAL;

ANIMALIA; ESCHERICHIA COLI; SUS SCROFA;

EID: 0031879158     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/11.7.583     Document Type: Article

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