K-RAS mutation and loss of heterozygosity of chromosome 17p and survival in colorectal cancer

Australian and New Zealand Journal of Surgery

Volumn 67, Issue 5, 1997, Pages 239-244

  Fung, Caroline ^a   Bragg, Tara ^a   Newland, Ronald ^a   Dent, Owen ^b   Nicholson, Garth ^a   Bokey, Lesley ^a   Chapuis, Pierre ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Chromosome 17p; Colorectal cancer; K ras; Mutation; p53; Survival

Indexed keywords

DNA;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CHROMOSOME 17P; CHROMOSOME DELETION; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; POLYMERASE CHAIN REACTION;

EID: 0030845484     PISSN: 00048682     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1445-2197.1997.tb01955.x     Document Type: Article

References (53)

1. Coates M, McCredie M, Taylor R. Cancer in New South Wales Incidence and Mortality 1991. Sydney: New South Wales Cancer Registry, Cancer Epidemiology Research Unit, 1994.
2. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-67.
3. Vogelstein B, Fearon ER, Hamilton SR et al. Genetic alterations during colorectal tumour development. N. Engl. J. Med. 1988; 319: 525-32.
4. Bos JL, Fearon ER, Hamilton SR et al. Prevalence of ras gene mutations in human colorectal cancer. Nature 1987; 327: 293-7.
5. Forrester K, Almoguera C, Han K, Grizzle WE, Perucho M. Detection of high incidence of k-ras oncogenes during human colon tumorigenesis. Nature 1987; 327: 298-303.
6. Ando M, Maruyama M, Oto M, Takemura K, Endo M, Yuasa Y. Higher frequency of point mutations in the c-K-ras 2 gene in human colorectal adenomas with severe atypia than in carcinomas. Jpn J. Cancer Res. 1991; 82: 245-9.
7. Sikura K, Chan S, Evan G et al. C-myc oncogene expression in colorectal cancer. Cancer 1987; 59: 1289-95.
8. Stewart J, Evan G, Watson J, Sikora K. Detection of the c-myc oncogene product in colonic polyps and carcinomas. Br. J. Cancer 1986; 53: 1-6.
9. Baker SJ, Fearon ER, Nigro JM et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 1989; 244: 217-21.
10. Kinzler KW. Identification of a gene located on chromosome 5q21 that is mutated in colorectal carcinomas. Science 1991; 251: 1366-70.
11. Nakamura Y, Lathrop M, Leppert M. Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5. Am. J. Hum. Genet. 1988; 43: 638-44.
12. Olschwang S, Laurent-Puig P, Melot T, Thuille B, Thomas G. High resolution genetic map of the adenomatous polyposis coli gene (APC) region. Am. J. Med. Genet. 1995; 56: 413-19.
13. Fearon ER, Cho KR, Nigro JM. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 1990; 247: 49-56.
14. Aaltonen LA, Peltomaki P, Leach FS et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260: 811-16.
15. Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260: 816-19.
16. Papadopoulos N, Nicolaides NC, Wei Y et al. Mutation of a mutL homolog in hereditary colon cancer. Science 1994; 263: 1625-9.
17. Bronner CE, Baker SM, Morrison PT et al. Mutation in the DNA mismatch repair gene homolog hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994; 368: 258-61.
18. Bell SM, Scott N, Cross D et al. Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer. Gastroenterology 1993; 104: 57-64.
19. Burmer GC, Loeb LA. Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma. Proc. Natl. Acad. Sci. USA 1989; 86: 2403-7.
20. Finkelstein S, Sayegh R, Christensen S, Swalsky P, Rogers A. The presence of k-ras-2 gene mutation in colorectal tumours: A combined histopathologic/genetic study of 50 cases. Lab. Invest. 1992; 66: A41.
21. Bos JL. Ras oncogenes in human cancer: A review. Cancer Res. 1989; 49: 4682-9.
22. Kern SE, Fearon ER, Tersmette KW et al. Allelic loss in colorectal carcinoma. JAMA. 1989; 261: 3099-103.
23. Hamelin R, Laurent-Puig P, Olschwang S et al. Association of p53 mutations with short survival in colorectal cancer. Gastroenterology 1994; 106: 42-8.
24. Kerr IB, Spandidos DA, Finlay IG, Lee FD, McArdle CS. The relation of ras family oncogene expression to conventional staging criteria and clinical outcome in colorectal carcinoma. Br. J. Cancer 1986; 53: 231-5.
25. Bren GD, Gomez T, Coggins JR et al. K-ras mutations in primary and metastatic colorectal neoplasm. Gastroenterology 1990; 98: A274.
26. Laurent-Puig P, Olschwang S, Delattre O et al. Association of ki-ras mutation with differentiation and tumour-formation pathways in colorectal carcinoma. Int. J. Cancer 1991; 49: 220-3.
27. Finkelstein SD, Sayegh R, Christensen S, Swalsky PA. Genotypic classification of colorectal adenocarcinoma. Cancer 1993; 71: 2827-38.
28. Finkelstein SD, Sayegh R, Bakker A, Swalsky P. Determination of tumour aggressiveness in colorectal cancer by k-ras-2 analysis. Arch. Surg. 1993; 128: 526-32.
29. Michelassi F, Grad G, Erroi F, Roncella M, Romagnoli J, Handcock M. Relationship between Ras oncogene expression and clinical and pathological features of colonic carcinoma. Hepatogastroenterology 1990; 37: 513-15.
30. Michelassi F, Erroi F, Roncella M, Block GE. Ras oncogene and the acquisition of metastasizing properties by rectal adenocarcinoma. Dis. Colon Rectum 1989; 32: 665-8.
31. Halter SA, Webb L, Rose J. Lack of ras mutations and prediction of long-term survival in carcinoma of the colon. Mod. Pathol. 1992; 5: 131-4.
32. Parada LF, Land H, Weinberg RA, Wolf D, Rotter V. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature 1984; 312: 649-51.
33. Chin K-V, Ueda K, Pastan I, Gottesman MM. Modulation of the activity of the promoter of the human MDR1 gene by Ras and p53. Science 1992; 255: 459-62.
34. Newland RC, Chapuis PH, Smyth EJ. The prognostic value of substaging colorectal carcinoma: A prospective study of 1117 cases with standardised pathology. Cancer 1987; 60: 852-7.
35. Newland RC, Dent OF, Chapuis PH, Bokey EL. Clinicopathologically diagnosed residual tumour after resection forcolorectal cancer. A 20 year prospective study. Cancer 1993; 72: 1536-42.
36. Fielding LP, Arsenault PA, Chapuis PH et al. Working Party Report to the World Congresses of Gastroenterology, Sydney 1990. Clinicopathological staging for colorectal cancer: An International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT). J. Gastroenterol. Hepatol. 1991; 6: 325-44.
37. Haliassos A, Chomel JC, Grandjouan S, Kruth J, Kaplan JC, Kitzis A. Detection of minority point mutations by modified PCR technique: A new approach for a sensitive diagnosis of tumour-progression markers. Nucleic Acids Res. 1989; 17: 8093-9.
38. Lothe RA, Nakamura Y, Woodward S, Gedde-Dahl Jr T, White R. VNTR (variable number of tandem repeats) markers show loss of chromosome 17p sequences in human colorectal carcinomas. Cytogenet. Cell Genet 1988; 48: 167-9.
39. Weber JL. Human DNA polymorphisms and methods of analysis. Curr. Opin. Biotechnol. 1990; 1: 166-71.
40. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. Am. Star. Assoc. J. 1958; 53: 457-81.
41. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer Inst. 1959; 22: 719-48.
42. EGRET. Statistics and Epidemiology Research Corporation, Seattle, 1991.
43. Cox DR. Regression models and life tables. J. R. Stat. Soc. 1972B; 34: 187-202.
44. Cohn KH, Wang F, DeSoto-LaPaix F et al. Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma. Lancet 1991; 338: 722-4.
45. Jen J, Kim H, Piantadosi S et al. Allelic loss of chromosome 18q and prognosis in colorectal cancer. N. Engl. J. Med. 1994; 331: 213-21.
46. Span M, Moerkerk P, De Goeij A, Arends J. A detailed analysis of K-ras point mutations in relation to tumour progression and survival in colorectal cancer patients. Int. J. Cancer 1996; 69: 241-5.
47. Moerkerk P, Arends J, van Driel M, De Bruine A, de Goeij A, ten Kate J. Type and number of K-ras point mutations relate to stage of human colorectal cancer. Cancer Res. 1994; 54: 3376-8.
48. Hayashi N, Ito I, Yanagisawa A et al. Genetic diagnosis of lymph-node metastasis in colorectal cancer. Lancet 1995; 345: 1257-9.
49. Bulfill JA. Colorectal cancer: Evidence for distinct genetic categories based on proximal or distal tumour location. Ann. Intern. Med. 1990; 113: 779-88.
50. Shaw P, Tardy S, Benito E, Obrador A, Costa J. Occurrence of Ki-ras and p53 mutations in primary colorectal tumours. Oncogene 1991; 6: 2121-8.
51. Laurent-Puig P, Delattre O, Olschwang S et al. A joint study of mutation of the ki ras oncogene and overexpression of the Tp53 oncogene in colorectal cancer. Gastroenterol. Clin. Biol. 1990; 14: 347-51.
52. Wyllie AH, Lang S, Purdie CA, Evans I, Bird CC. p53 and Ki ras oncogenes do not co-operate in human colorectal carcinogenesis. J. Pathol. 1991; 163: A169.
53. Bertorelle R, Esposito G, Del Mistro A et al. Association of p53 gene and protein alterations with metastases in colorectal cancer. Am. J. Surg. Pathol. 1995; 19: 463-71.