PKC regulation of cardiac CFTR Cl- channel function in guinea pig ventricular myocytes

American Journal of Physiology - Cell Physiology

Volumn 275, Issue 1 44-1, 1998, Pages

  Middleton, Lisa M ^a   Harvey, Robert D ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bisindolylmaleimide; Cardiac isoform of cystic fibrosis transmembrane conductance regulator; Chelerythrine; Cross talk; Phorbol 12,13 dibutyrate; Protein kinase C

Indexed keywords

BISINDOLYLMALEIMIDE; CHELERYTHRINE; CHLORIDE CHANNEL; ISOPRENALINE; PHORBOL DIBUTYRATE; PROTEIN KINASE C; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHLORIDE CURRENT; ENZYME ACTIVITY; GUINEA PIG; HEART MUSCLE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0031873373     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1998.275.1.c293     Document Type: Article

References (39)

1. - channel gating to an ATP hydrolysis cycle. Neuron 12: 473-482, 1994.
2. Bazzi, M., and G. Nelsestuen. Properties of the protein kinase C-phorbol ester interaction. Biochemistry 28: 3577-3585, 1989.
3. - channel by specific protein kinases and protein phosphatases. J. Biol. Chem. 268: 2037-2047, 1993.
4. Chang, X.-B., J. A. Tabcharani, Y.-X. Hou, T. J. Jensen, N. Kartner, N. Alon, J. W. Hanrahan, and J. R. Riordan. Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites. J. Biol. Chem. 268: 11304-11311, 1993.
5. Collier, M. L., and J. R. Hume. Unitary chloride channels activated by protein kinase C in guinea pig ventricular myocytes. Circ. Res. 76: 317-324, 1995.
6. Dechecchi, M. C., R. Rolfini, A. Tamanini, C. Gamberi, G. Berton, and G. Cabrini. Effect of modulation of protein kinase C on the cAMP-dependent chloride conductance in T84 cells. FEBS Lett. 311: 25-28, 1992.
7. Du, X. Y., and S. Sorota. Protein kinase C stimulates swelling-induced chloride current in canine atrial cells (Abstract). Circulation 96: 1-730, 1997.
8. - currents in rabbit atrial myocytes. Circ. Res. 77: 379-393, 1995.
9. Dulhanty, A. M., and J. R. Riordan. Phosphorylation by cAMP-dependent protein kinase causes a conformational change in the R domain of the cystic fibrosis transmembrane conductance regulator. Biochemistry 33: 4072-4079, 1994.
10. Eckly-Michel, A. E., A. Le Bec, and C. Lugnier. Chelerythrine, a protein kinase C inhibitor, interacts with cyclic nucleotide phosphodiesterases. Eur. J. Pharmacol. 324: 85-88, 1997.
11. Gadsby, D. C., and A. C. Nairn. Regulation of CFTR channel gating. Trends Biochem. Sci. 19: 513-518, 1994.
12. Hamill, O. P., A. Marty, E. Neher, B. Sakmann, and F. J. Sigworth. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391: 85-100, 1981.
13. Hart, P., J. D. Warth, P. C. Levesque, M. L. Collier, Y. Geary, B. Horowitz, and J. R. Hume. Cystic fibrosis gene encodes a cAMP-dependent chloride channel in heart. Proc. Natl. Acad. Sci. USA 93: 6343-6348, 1996.
14. Harvey, R. D., C. D. Clark, and J. R. Hume. Chloride current in mammalian cardiac myocytes. Novel mechanism for autonomic regulation of action potential duration and resting membrane potential. J. Gen. Physiol. 95: 1077-1102, 1990.
15. Herbert, J. M., J. M. Augereau, J. Gleye, and J. P. Maffrand. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 172: 993-999, 1990.
16. - channels in heart. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H2214-H2220, 1993.
17. s-stimulated adenylyl cyclases. FASEB J. 7: 768-775, 1993.
18. James, A. F., T. Tominaga, Y. Okada, and M. Tominaga. Distribution of cAMP-activated chloride current and CFTR mRNA in the guinea pig heart. Circ. Res. 79: 201-207, 1996.
19. Jia, Y., C. J. Mathews, and J. W. Hanrahan. Phosphorylation by protein kinase C is required for acute activation of cystic fibrosis transmembrane conductance regulator by protein kinase A. J. Biol. Chem. 272: 4978-4984, 1997.
20. Jiang, T. R., E. Pak, H. L. Zhang, R. P. Kline, and S. F. Steinberg. Endothelin-dependent actions in cultured AT-1 cardiac myocytes: the role of the ε isoform of protein kinase C. Circ. Res. 78: 724-736, 1996.
21. Martiny-Baron, G., M. G. Kazanietz, H. Mischak, P. M. Blumberg, G. Kochs, H. Hug, D. Marmé, and C. Schächtele. Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. J. Biol. Chem. 268: 9194-9197, 1993.
22. Newton, A. C. Regulation of protein kinase C. Curr. Opin. Cell Biol. 9: 161-167, 1997.
23. Nishizuka, Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature 308: 693-698, 1984.
24. 1-Adrenergic inhibition of the β-adrenergically activated chloride current in guinea-pig ventricular myocytes. Circ. Res. 78: 1090-1099, 1996.
25. Paul, K., N. A. Ball, G. W. Dorn II, and R. A. Walsh. Left ventricular stretch stimulates angiotensin II-mediated phosphatidylinositol hydrolysis and protein kinase C ε isoform translocation in adult guinea pig hearts. Circ. Res. 81: 643-650, 1997.
26. Riordan, J. R., J. M. Rommens, B. Kerem, N. Alon, R. Rozmahel, Z. Grzelczak, J. Zielenski, S. Lok, N. Plavsic, J.-L. Chou, M. L. Drumm, M. C. Iannuzzi, F. S. Collins, and L.-C. Tsui. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245: 1066-1073, 1989.
27. Schluter, K. D., M. Weber, and H. M. Piper. Parathyroid hormone induces protein kinase C but not adenylate cyclase in adult cardiomyocytes and regulates cyclic AMP levels via protein kinase C-dependent phosphodiesterase activity. Biochem. J. 310: 439-444, 1995.
28. Shuba, L. M., T. Asai, and T. F. McDonald. Phorbol ester activation of chloride current in guinea-pig ventricular myocytes. Br. J. Pharmacol. 117: 1395-1404, 1996.
29. Steinberg, S. F., M. Goldberg, and V. O. Rybin. Protein kinase C isoform diversity in the heart. J. Mol. Cell. Cardiol. 27: 141-153, 1995.
30. - channel in CHO cells stably expressing the cystic fibrosis gene. Nature 352: 628-631, 1991.
31. Toullec, D., P. Pianetti, H. Coste, P. Bellevergue, T. Grand-Perret, M. Ajakane, V. Baudet, P. Boissin, E. Boursier, F. Loriolle, L. Duhamel, D. Charon, and J. Kirilovsky. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266: 15771-15781, 1991.
32. Vandenberg, J. I., A. Yoshida, K. Kirk, and T. Powell. Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology. J. Gen. Physiol. 104: 997-1017, 1994.
33. Walsh, K. B. Activation of a heart chloride current during stimulation of protein kinase C. Mol. Pharmacol. 40: 342-346, 1991.
34. Walsh, K. B and K. J. Long. Properties of a protein kinase C-activated chloride current in guinea pig ventricular myocytes. Circ. Res. 74: 121-129, 1994.
35. Warth, J. D., M. L. Collier, P. Hart, Y. Geary, C. H. Gelband, T. Chapman, B. Horowitz, and J. R. Hume. CFTR chloride channels in human and simian heart. Cardiovasc. Res. 31: 615-624, 1996.
36. Wilkinson, D. J., T. V. Strong, M. K. Mansoura, D. L. Wood, S. S. Smith, F. S. Collins, and D. C. Dawson. CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L127-L133, 1997.
37. Winpenny, J. P., H. L. McAlroy, M. A. Gray, and B. E. Argent Protein kinase C regulates the magnitude and stability of CFTR currents in pancreatic duct cells. Am. J. Physiol 268 (Cell Physiol. 37): C823-C828, 1995.
38. - current in dialyzed cardiac myocytes. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1795-H1802, 1995.
39. - currents in feline ventricular myocytes. Circ. Res. 75: 133-143, 1994