α1-adrenergic inhibition of the β-adrenergically activated Cl- current in guinea pig ventricular myocytes

Circulation Research

Volumn 78, Issue 6, 1996, Pages 1090-1099

  Oleksa, Lisa M ^a   Hool, Livia C ^a   Harvey, Robert D ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

acetylcholine; isoproterenol; methoxamine; phorbol 12,13 dibutyrate; protein kinase C

Indexed keywords

ACETYLCHOLINE; ADENYLATE CYCLASE; ALPHA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CHLORIDE ION; FORSKOLIN; HISTAMINE; ISOBUTYLMETHYLXANTHINE; ISOPRENALINE; MALEIMIDE DERIVATIVE; METHOXAMINE; NISOLDIPINE; NORADRENALIN; PERTUSSIS TOXIN; PHORBOL DIBUTYRATE; PHOSPHODIESTERASE; PRAZOSIN; PROTEIN KINASE C; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ALPHA ADRENERGIC RECEPTOR BLOCKING; ANIMAL CELL; ARTICLE; BETA ADRENERGIC STIMULATION; CHLORIDE CONDUCTANCE; CHLORIDE CURRENT; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GUINEA PIG; HEART VENTRICLE WALL; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; VOLTAGE CLAMP;

EID: 0029888788     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.78.6.1090     Document Type: Article

References (41)

1. 1-Adrenoceptors in myocardium: functional aspects and transmembrane signaling mechanisms. Physiol Rev. 1993;73:469-487.
2. 1-adrenoceptors: an overview. Pharmacol Rev. 1993;45:147-175.
3. - currents in rabbit atrial myocytes: characterization of a novel ionic regulatory mechanism. Circ Res. 1995;77:379-393.
4. Walsh KB. Activation of a heart chloride current during stimulation of protein kinase C. Mol Pharmacol. 1991;40:342-346.
5. - channels in heart. Am J Physiol. 1993;264:H2214-H2220.
6. Bahinski A, Nairn AC, Greengard P, Gadsby DC. Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes. Nature. 1989;340:718-721.
7. Harvey RD, Hume JR. Autonomic regulation of a chloride current in heart. Science. 1989;244:983-985.
8. - channel by specific protein kinases and protein phosphatases. J Biol Chem. 1993;268:2037-2047.
9. - channel in CHO cells stably expressing the cystic fibrosis gene. Nature. 1991;352:628-631.
10. Chang X-B, Tabcharani JA, Hou Y-X, Jensen TJ, Kartner N, Alon N, Hanrahan JW, Riordan JR. Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites. J Biol Chem. 1993;268:11304-11311.
11. Collier ML, Hume JR. Unitary chloride channels activated by protein kinase C in guinea pig ventricular myocytes. Circ Res. 1995;76:317-324.
12. Walsh KB, Long KJ. Properties of a protein kinase C-activated chloride current in guinea pig ventricular myocytes. Circ Res. 1994;74:121-129.
13. - currents in feline ventricular myocytes. Circ Res. 1994;75:133-143.
14. Harvey RD, Clark CD, Hume JR. Chloride current in mammalian cardiac myocytes: novel mechanism for autonomic regulation of action potential duration and resting membrane potential. J Gen Physiol. 1990;95:1077-1102.
15. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 1981;391:85-100.
16. Fabiato A. Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands. Methods Enzymol. 1988;157:378-416.
17. Datyner NB, Gintant GA, Cohen IS. Versatile temperature controlled tissue bath for studies of isolated cells using an inverted microscope. Pflugers Arch. 1985;403:318-323.
18. - current in dialyzed cardiac myocytes. Am J Physiol. 1995;268:H1795-H1802.
19. 125I]IBE 2254 are bound specifically to a receptor population with high affinity and low density. Arch Int Pharmacodyn Ther. 1987;289:234-250.
20. Harvey RD. Effects of stilbenedisulfonic acid derivatives on the cAMP-regulated chloride current in cardiac myocytes. Pflugers Arch. 1993;422:436-442.
21. Walsh KB, Kass RS. Regulation of a heart potassium channel by protein kinase A and C. Science. 1988;242:67-69.
22. Yazawa K, Kameyama M. Mechanism of receptor-mediated modulation of the delayed outward potassium current in guinea-pig ventricular myocytes. J Physiol (Lond). 1990;421:135-150.
23. Tohse N, Kameyama M, Sekiguchi K, Shearman MS, Kanno M. Protein kinase C activation enhances the delayed rectifier potassium current in guinea-pig heart cells. J Mol Cell Cardiol. 1990;22:725-734.
24. + current of guinea pig ventricular cells through the activation of protein kinase C. Circ Res. 1992;71:1441-1446.
25. + current in mammalian heart involves G proteins. Am J Physiol. 1989;257:H818-H823.
26. Hwang T-C, Horie M, Nairn AC, Gadsby DC. Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance. J Gen Physiol. 1992;99:465-489.
27. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, Baudet V, Boissin P, Boursier E, Loriolle F, Duhamel L, Charon D, Kirilovsky J. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem. 1991;266:15771-15781.
28. Hartzell HC. Regulation of cardiac ion channels by catecholamines, acetylcholine and second messenger systems. Prog Biophys Mol Biol. 1988;52:165-247.
29. Overholt JL, Hobert ME, Harvey RD. On the mechanism of rectification of the isoproterenol-activated chloride current in guinea-pig ventricular myocytes. J Gen Physiol. 1993;102:871-895.
30. Huang K-P. The mechanism of protein kinase C activation. Trends Neurosci. 1989;12:425-432.
31. - current. Circulation. 1995;92(suppl I):I-576. Abstract.
32. Hoffman BB, Lefkowitz RJ. Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG, eds. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill Publishing Co; 1995:199-248.
33. Hwa J, De Young MB, Perez DM, Graham RM. Autonomic control of myocardium: alpha-adrenoceptor mechanisms. In: Shepherd J, Vatner SF, eds. The Nervous Control of the Heart. Cambridge, Mass: Harvard Academic Press; 1996.
34. Bylund DB, Eikenberg DC, Hieble JP, Langer SZ, Lefkowitz RJ, Minneman KP, Molinoff PB, Ruffolo RR Jr, Trendelenburg U. International union of pharmacology nomenclature of adrenoceptors. Pharmacol Rev. 1994;46:121-136.
35. 2-adrenoceptors in rat isolated kidney: involvement of purines and prostaglandins. Naunyn Schmiedebergs Arch Pharmacol. 1993;347:273-279.
36. 3H)-prazosin. Biochem Biophys Res Commun. 1979;90:142-149.
37. K via a pertussis toxin-sensitive pathway. Biophys J. 1988;54:219-225.
38. Buxton IL, Brunton LL. Action of the cardiac alpha 1-adrenergic receptor: activation of cyclic AMP degradation. J Biol Chem. 1985;260:6733-6737.
39. 1- and β-adrenergic interactions on L-type calcium current in cardiac myocytes. Pflugers Arch. 1992;421:397-399.
40. 1-adrenoceptor-mediated inhibition of cellular cAMP accumulation in neonatal rat ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol. 1993;347:384-393.
41. Kurz T, Yamada KA, DaTorre SD, Corr PB. Alpha 1-adrenergic system and arrhythmias in ischaemic heart disease. Eur Heart J. 1991;12(suppl F):88-98.