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Volumn 53, Issue 6, 1998, Pages 1120-1130

On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CARBACHOL; CHOLINERGIC RECEPTOR; MUSCARINIC M1 RECEPTOR; PIRENZEPINE; XANOMELINE;

EID: 0031866950     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (28)
  • 1
    • 0009644628 scopus 로고
    • Some quantitative uses of drug antagonists
    • Arunlakshana O and Schild HO (1959) Some quantitative uses of drug antagonists. Br J Pharmacol 14:48-58.
    • (1959) Br J Pharmacol , vol.14 , pp. 48-58
    • Arunlakshana, O.1    Schild, H.O.2
  • 3
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Annal Biochem 72:248-254.
    • (1976) Annal Biochem , vol.72 , pp. 248-254
    • Bradford, M.1
  • 4
    • 0024378999 scopus 로고
    • Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum
    • Bredt DS and Snyder SH (1989) Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci USA 86:9030-9033.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9030-9033
    • Bredt, D.S.1    Snyder, S.H.2
  • 7
    • 0030024180 scopus 로고    scopus 로고
    • 2-adrenergic receptor stimulation of adenylyl cyclase by salmeterol: Evidence for a quasi-irreversible binding to an exosite
    • 2-adrenergic receptor stimulation of adenylyl cyclase by salmeterol: evidence for a quasi-irreversible binding to an exosite. Mol Pharmacol 49:182-189.
    • (1996) Mol Pharmacol , vol.49 , pp. 182-189
    • Clark, R.B.1    Allal, C.2    Friedman, J.3    Johnson, M.4    Barber, R.5
  • 8
    • 0030247623 scopus 로고    scopus 로고
    • Exosites: Their current status, and their relevance to the duration of action of long-acting β2-adrenoceptor agonists
    • Coleman RA, Johnson M, Nials AT, and Vardey CJ (1996) Exosites: their current status, and their relevance to the duration of action of long-acting β2-adrenoceptor agonists. Trends Pharmacol Sci 17:324-330.
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 324-330
    • Coleman, R.A.1    Johnson, M.2    Nials, A.T.3    Vardey, C.J.4
  • 9
    • 0028919316 scopus 로고
    • Attenuation of muscarinic receptor-G-protein interaction in Alzheimer disease
    • Ferrari-Dileo G, Mash DC, and Flynn, DD (1995) Attenuation of muscarinic receptor-G-protein interaction in Alzheimer disease. Mol Chem Neuropathol 24:69-91.
    • (1995) Mol Chem Neuropathol , vol.24 , pp. 69-91
    • Ferrari-Dileo, G.1    Mash, D.C.2    Flynn, D.D.3
  • 10
    • 0002361315 scopus 로고
    • Cholinomimetic replacement of cholinergic function in Alzheimer's disease
    • Meyer EM, Simpkins JW, Yamamoto J, and Crews FT, eds, Plenum Press, NY
    • Giacobini E (1992) Cholinomimetic replacement of cholinergic function in Alzheimer's disease, in Treatment of Dementias (Meyer EM, Simpkins JW, Yamamoto J, and Crews FT, eds) pp 19-34, Plenum Press, NY.
    • (1992) Treatment of Dementias , pp. 19-34
    • Giacobini, E.1
  • 12
    • 0025856977 scopus 로고
    • Effects of agonist efficacy on desensitization of phosphoinositide hydrolysis mediated by m1 and m3 muscarinic receptors expressed in Chinese hamster ovary cells
    • Hu J, Wang SZ, and El-Fakahany EE (1991) Effects of agonist efficacy on desensitization of phosphoinositide hydrolysis mediated by m1 and m3 muscarinic receptors expressed in Chinese hamster ovary cells J Pharmacol Exp Ther 257:938-945.
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 938-945
    • Hu, J.1    Wang, S.Z.2    El-Fakahany, E.E.3
  • 15
    • 0030218059 scopus 로고    scopus 로고
    • Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation
    • Kostenis E and Mohr K (1996) Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation. Trends Pharmacol Sci 17:280-283.
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 280-283
    • Kostenis, E.1    Mohr, K.2
  • 17
    • 0029126526 scopus 로고
    • Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: Interactions of strychnine and acetyicholine at muscarinic receptors
    • Lazareno S and Birdsall NJM (1995) Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetyicholine at muscarinic receptors. Mol Pharmacol 48:362-378.
    • (1995) Mol Pharmacol , vol.48 , pp. 362-378
    • Lazareno, S.1    Birdsall, N.J.M.2
  • 18
    • 0025875643 scopus 로고
    • Allosteric antagonists of the muscarinic acetylcholine receptor
    • Lee NH and El-Fakahany EE (1991) Allosteric antagonists of the muscarinic acetylcholine receptor. Biochem Pharmacol 42:199-205.
    • (1991) Biochem Pharmacol , vol.42 , pp. 199-205
    • Lee, N.H.1    El-Fakahany, E.E.2
  • 19
    • 0025212261 scopus 로고
    • Estimation of agonist affinity and efficacy by direct, operational model fitting
    • Leff P, Prentice DJ, Giles H, Martin GR, and Wood J (1990) Estimation of agonist affinity and efficacy by direct, operational model fitting. J Pharmacol Methods 23:225-237.
    • (1990) J Pharmacol Methods , vol.23 , pp. 225-237
    • Leff, P.1    Prentice, D.J.2    Giles, H.3    Martin, G.R.4    Wood, J.5
  • 20
    • 0027375964 scopus 로고
    • Molecular mechanisms of membrane receptor desensitization
    • Lohse MJ (1993) Molecular mechanisms of membrane receptor desensitization. Biochim Biophys Acta 1179:171-188.
    • (1993) Biochim Biophys Acta , vol.1179 , pp. 171-188
    • Lohse, M.J.1
  • 21
    • 0021962590 scopus 로고
    • Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation
    • Mash DC, Flynn DD, and Potter LT (1985) Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation. Science (Washington D C) 228:1115-1117.
    • (1985) Science (Washington D C) , vol.228 , pp. 1115-1117
    • Mash, D.C.1    Flynn, D.D.2    Potter, L.T.3
  • 22
    • 0002704168 scopus 로고
    • Regulation and development of muscarinic receptor number and function
    • Brown JH, ed, Humana Press, NJ
    • Nathanson NM (1989) Regulation and development of muscarinic receptor number and function, in The Muscarinic Receptors (Brown JH, ed) pp 419-454, Humana Press, NJ.
    • (1989) The Muscarinic Receptors , pp. 419-454
    • Nathanson, N.M.1
  • 24
    • 0028231689 scopus 로고
    • Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic receptors
    • Proška J and Tucek S (1994) Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic receptors. Mol Pharmacol 45:709-717.
    • (1994) Mol Pharmacol , vol.45 , pp. 709-717
    • Proška, J.1    Tucek, S.2
  • 27
    • 0028297202 scopus 로고
    • Efficient coupling of m5 muscarinic acetyicholine receptors to activation of nitric oxide synthase
    • Wang SZ, Zhu SZ, and El-Fakahany EE (1994) Efficient coupling of m5 muscarinic acetyicholine receptors to activation of nitric oxide synthase. J Pharmacol Exp Ther 268:552-557.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 552-557
    • Wang, S.Z.1    Zhu, S.Z.2    El-Fakahany, E.E.3
  • 28
    • 0009603660 scopus 로고
    • An arginine residue conserved in most G protein-coupled receptors is essential for the function of the m1 muscarinic receptor
    • Zhu SZ, Wang SZ, Hu J, and El-Fakahany EE (1994) An arginine residue conserved in most G protein-coupled receptors is essential for the function of the m1 muscarinic receptor. Mol Pharmacol 45:517-523.
    • (1994) Mol Pharmacol , vol.45 , pp. 517-523
    • Zhu, S.Z.1    Wang, S.Z.2    Hu, J.3    El-Fakahany, E.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.