Modulation of extracellular GABA levels in the retina by activation of glial P2X-purinoceptors

British Journal of Pharmacology

Volumn 124, Issue 2, 1998, Pages 317-322

  Neal, M J ^a   Cunningham, J R ^a   Dent, Z ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

ATP; GABA release; GABA uptake; Glia; Muller cells; Retina

Indexed keywords

1 (4,4 DIPHENYL 3 BUTENYL)NIPECOTIC ACID; 2 CHLOROADENOSINE 5' TRIPHOSPHATE; 2 METHYLTHIOADENOSINE TRIPHOSPHATE; 4 AMINOBUTYRIC ACID; ADENOSINE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; BETA,GAMMA METHYLENEADENOSINE TRIPHOSPHATE; CALCIUM ION; POTASSIUM CHLORIDE; PURINE ANTAGONIST; PURINE P2X RECEPTOR;

4 AMINOBUTYRIC ACID RELEASE; 4 AMINOBUTYRIC ACID UPTAKE; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SLICE; CONTROLLED STUDY; FEMALE; FROG; GLIA CELL; MALE; MUELLER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA; SIGNAL TRANSDUCTION;

EID: 0031863227     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701841     Document Type: Article

References (35)

1. ANSSELIN, A.D., DAVEY, D.F. & ALLEN, D.G. (1997). Extracellular ATP increases intracellular calcium in cultured adult Schwann cells. Neuroscience, 76, 947-955.
2. BLAZYNSKI, C. (1989). Displaced cholinergic GABAergic amacrine cells in the rabbit retina also contain adenosine. Vis. Neurosci., 3, 425-431.
3. BLAZYNSKI, C. & PEREZ, M.T.R. (1991). Adenosine in vertebrate retina: localization, receptor characterization and function. Cell. Mol. Neurobiol., 11, 463-484.
4. BOLEGO, C., CERUTI, S., BRAMBILLA, R., PUGLISI, L., CATTABENI, F., BURNSTOCK, G. & ABBRACCHIO, M.P. (1997). Characterization of the signalling pathways involved in ATP and basic fibroblast growth factor-induced astrogliosis. Br. J. Pharmacol., 121, 1692-1699.
5. BOYER, J.L., ZOHN, I.E., JACOBSON. K.A. & HARDEN, T.K. (1994). Differential effects of P2-purinoceptor antagonists on phospholipase C and adenylyl cyclase-coupled P2Y-purinoceptors. Br. J. Pharmacol., 113, 614-620.
6. BURNSTOCK, G. (1997). The past, present and future of purine nucleotides as signalling molecules. Neuropharmacology, 36, 1127-1139.
7. 2+ responses evoked by ATP and other nucleotides in mammalian brain astrocytes. Br. J. Pharmacol., 121, 1700-1706.
8. CUNNINGHAM, J.R. & NEAL, M.J. (1983). Effect of γ-aminobutyric acid agonists, glycine, taurine and neuropeptides on acetylcho-line release from the rabbit retina. J. Physiol., 336, 563-577.
9. EDWARDS, F.A., GIBB, A.J. & COLQUHOUN, D. (1992). ATP receptor-mediated synaptic current in the central nervous system. Nature, 359, 144-147.
10. EVANS, R.J. & SURPRENANT, A. (1996). P2X receptors in autonomic and sensory neurons. Sem. Neurosci., 8, 217-223.
11. 2x2-receptor subunit of the ATP-gated ion channel in the retina. Neuro Report, 8, 1083-1088.
12. HONDA, S., YAMAMOTO, M. & SAITO, N. (1995). Immunocytochemical localization of three subtypes of GABA transporter in rat retina. Mol. Brain Res., 33, 319-325.
13. HUMPHREY, P.P.A., BUELL, G., KENNEDY, I., KHAKH, B.S. MICHEL, A.D., SURPRENANT, A. & TREZISE, D.J. (1995). New insights on P2X purinoceptors. Naunyn-Schmiedeberg's Arch. Pharmacol., 352, 585-596.
14. 3H]-glycine in slices and homogenates of rat brain and cord by electron microscope autoradiography. Brain Res., 41, 131-143.
15. KEIRSTEAD, S.A. & MILLER, R.F. (1997). Activation of purinoceptors on Müller cells evokes calcium release from internal stores. Soc. Neurosci. Abst., 498.13.
16. NEAL, M.J. & BOWERY, N.G. (1979). Differential effects of veratridine and potassium depolarization on neuronal and glial GABA release. Brain Res., 167, 337-343.
17. NEAL, M.J. & CUNNINGHAM, J.R. (1994). Modulation by endogenous ATP of the light-evoked release of ACh from retinal cholinergic neurones. Br. J. Pharmacol., 113, 1085-1087.
18. 3H](±)-aminocyclohexane carboxylic acid, a selective inhibitor of neuronal GABA transport. Brain Res., 176, 285-296.
19. NEAL, M.J., CUNNINGHAM, J.R. & PATERSON, S.J. (1995). Binding sites for α,β-methylene ATP are present in the vertebrate retina. Br. J. Pharmacol., 114, 101P.
20. NEAL, M.J., CUNNINGHAM, J.R., SHAH, M.A. & YAZULLA, S. (1989). Immunocytochemical evidence that vigabatrin in rats causes GABA accumulation in glial cells of the retina. Neurosci. Lett., 98, 29-32.
21. 3H]-GABA in rat retina. Nature New Biol., 235, 217-218.
22. NEWMAN, E.A. & REICHENBACH, A. (1996). The Müller cell: a functional element in the retina. Trends Neurosci., 19, 307-312.
23. NEWMAN, E.A. & ZAHS, K.R. (1997). Calcium waves in retinal glial cells. Science, 275, 844-847.
24. 2x-purinoceptor plethora. Sem. Neurosci., 8, 187-194.
25. PARPURA, V., LIU, F., JEFTINIJA, K.V., HAYDON, P.O. & JEFTINIJA, S.D. (1995). Neuroligand-evoked calcium dependent release of excitatory amino acids from Schwann cells. J. Neurosci., 15, 5831-5839.
26. PEREZ, M.T.R., ARNER, K. & EHINGER, B. (1988). Stimulation evoked release of purines from rabbit retina. Neurochem. Int., 13, 307-318.
27. PEREZ, M.T.R., EHINGER, B., LINSTROM, K. & FREDHOLM, B.B. (1986). Release of endogenous and radioactive purines from the rabbit retina. Brain Res., 398, 106-112.
28. ROBITAILLE, R. (1995). Purinergic receptors and their activation by endogenous purines at perisynaptic glial cells of the frog neuromuscular junction. J. Neurosci., 15, 7121-7131.
29. SALTER, M.W. & HICKS, J.L. (1994). ATP-evoked increases in intracellular calcium in neurons and glia from the dorsal spinal cord. J. Neurosci., 14, 1563-1575.
30. 2x-receptor for extra-cellular ATP. Nature, 371, 516-519.
31. 3 receptor subunits in rat and monkey sensory neurons and their central terminals. Neuropharmacology, 36, 1229-1242.
32. WINDSCHEIF, U., PFAFF, G., ZIGANSHIN, A.U., HOYLE, C.H., BAUMERT, H.G., MUTSCHLER, E., BURNSTOCK, G. & LAMBRECHT, G. (1995). Inhibitory action of PPADS on relaxant response to adenine nucleotides or electrical field stimulation in guinea pig taenia coli and rat duodenum. Br. J. Pharmacol., 115, 1509-1517.
33. WINDSCHEIF, U., RALEVIC, V., BAUMERT, H.G., MUTSCHLER, E., LAMBRECHT, G. & BURNSTOCK, G (1994). Vasoconstrictor and vasodilator responses to various agonists in the rat perfused mesenteric arterial bed: selective inhibition by PPADS of contractors via P2X-purinoceptors. Br. J. Pharmacol., 113, 1015-1021.
34. ZHOU, Z.J. & FAIN, G.L. (1995). Neurotransmitter receptors of starburst amacrine cells in rabbit retinal slices. J. Neurosci., 15, 5334-5345.
35. ZIGANSHIN, A.U., HOYLE, C.H.V., BO, X., LAMBRECHT, G., MUTSCHLER, E., BAUMERT, H.G. & BURNSTOCK, G. (1993). PPADS selectively antagonizes P2X-purinoceptor-mediated responses in the rabbit urinary bladder. Br. J. Pharmacol., 110, 1491-1495.