P2X purinoceptor plethora

Seminars in the Neurosciences

Volumn 8, Issue 4, 1996, Pages 187-194

  North, R Alan ^a  

^a GLAXO INST FOR MOLECULAR BIOLOGY   (Switzerland)

Author keywords

ATP; Homology; Ion channels; P2X; Protein structure

Indexed keywords

BRAIN RECEPTOR; PURINE P2X RECEPTOR; RECEPTOR SUBUNIT;

BRAIN; HUMAN; MAMMAL CELL; MEMBRANE CHANNEL; NONHUMAN; OOCYTE; PROTEIN STRUCTURE; REVIEW; SENSORY GANGLION; STOICHIOMETRY; TISSUE DISTRIBUTION; TISSUE SPECIFICITY;

EID: 0030220611     PISSN: 10445765     EISSN: None     Source Type: Journal    
DOI: 10.1006/smns.1996.0024     Document Type: Review

References (51)

1. 1. Burnstock G (1972) Purinergic nerves. Pharmacol Rev 24:509-581
2. 2. Burnstock G (1980) Purinergic nerves and receptors. Prog Biochem Pharmacol 16:141-154
3. 3. Jahr CE, Jessell TM (1983) ATP excites a subpopulation of rat dorsal horn neurones. Nature 304:730-733
4. 4. Krishtal OA, Marchenko SM, Pidoplichko VI (1983) Receptor for ATP in the membrane of mammalian sensory neurones. Neurosci Lett 35:41-45
5. 2+-permeable channel activated by ATP in smooth muscle. Nature 328:275-278
6. 6. Bean BP (1992) Pharmacology and electrophysiology of ATP-activated ion channels. Trends Pharmacol Sci 13:87-90
7. 2 purinoceptor? Gen Pharmacol 16:433-440
8. 8. Lambrecht G, Friebe T, Grimm U, Windscheif U, Bungardt E, Hildebrandt C, Bäamert HG, Spatz-Kumbel G, Mutschler E (1992) PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses. Eur J Pharmacol 217:217-219
9. 9. Evans RJ, Surprenant A (1992) Vasoconstriction of guinea-pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP. Br J Pharmacol 106:242-249
10. 10. Evans RJ, Derkach V, Surprenant A (1992) ATP mediates fast synaptic transmission in mammalian neurons. Nature 357:503-505
11. 11. Edwards FA, Gibb AJ, Colquhoun D (1992) ATP receptor-mediated synaptic currents in the central nervous system. Nature 359:144-147
12. 2x receptor for extracellular ATP. Nature 371:516-519
13. 13. Brake AJ, Wagenbach MJ, Julius D (1994) New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371:519-523
14. 14. Lewis C, Neidhart S, Holy C, North RA, Buell G, Surprenant A (1995) Heteropolymerization of P2X receptor subunits can account for ATP-gated currents in sensory neurons. Nature 377:432-435
15. 15. Chen C, Akopian AN, Sivilotti L, Colquhoun D, Burnstock G, Wood JN (1995) A P2X receptor expressed by a subset of sensory neurons. Nature 377:428-430
16. 2x receptor expressed in epithelia and brain. EMBO J 15:55-62
17. 17. Bo X, Zhang Y, Nassar M, Burnstock G, Schoepfer R (1995) A P2X purinoceptor cDNA conferring a novel pharmacological profile. FEBS Lett 375:129-133
18. 18. Soto F, Garcia-Guzman M, Gomez-Hernandez JM, Hollmann M, Karschin C, Stuhmer W (1996) P2Xα4: an ATP-activated ionotropic receptor cloned from rat brain. Proc Natl Acad Sci USA 93:3684-3688
19. 19. Seguela P, Haghihi A, Soghomonian J-J, Cooper E (1996) A novel neuronal P2X ATP receptor ion channel with widespread distribution in the brain. J Neurosci 16:448-455
20. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J Neurosci 16:2495-2507
21. 21. Valera S, Talabot F, Evans RJ, Gos A, Antonarakis SE, Morris MA, Buell GN (1995) Characterization and chromosomal localization of a human P2X receptor from urinary bladder. Receptors Channels 3:283-289
22. 22. Owens GP, Hahn WE, Cohen JJ (1991) Identification of mRNAs associated with programmed cell death in immature thymocytes. Mol Cell Biol 11:4177-4188
23. 23. Housley GD, Greenwood DR, Bennett T, Ryan AF (1995) Identification of a short form of the P2XR1-purinoceptor subunit produced by alternative splicing in the pituitary and cochlea. Biochem Biophys Res Commun 212:501-508
24. 24. Kidd EJ, Grahames CBA, Simon J, Michel AD, Barnard EA, Humphrey PPA (1995) Localization of P2X purinoceptor transcripts in the rat nervous system. Mol Pharmacol 48:569-573
25. 25. Jiang S, Kull B, Fredholm BB, Orrenius S (1996) P2X purinoceptor is not important in thymocyte apoptosis. Immunol Lett, in press
26. 26. Buell G, Michel AD, Lewis C, Collo G, Humphrey PPA, Surprenant A (1996) P2X1 receptor activation in HL60 cells. Blood 67:2659-2664
27. 27. Vulchanova L, Arvidsson U, Riedl M, Buell G, Surprenant A, North RA, Elde RP (1995) Differential distribution of ATP-gated ion channels (P2X receptors) as determined by immunohistochemistry. Soc Neurosci Abstr 21:55
28. 28. Reithmeier RAF (1995) Characterization and modeling of membrane proteins using sequence analysis. Curr Opin Struct Biol 5:491-500
29. 29. White SH (ed.) Membrane Protein Structure. Oxford University Press, New York
30. 30. von Heijne G (1992) Membrane protein structure prediction - hydrophobicity analysis and the positive inside rule. J Mol Biol 225:487-494
31. 31. Werner P, Seward E, Buell G, North RA (1995) Structural determinants of ATP-gated channels. Soc Neurosci Abst 21:1262
32. + channel (αrENaC) mediates its localisation at the apical membrane. EMBO J 13:4440-4450
33. 33. Evans RJ, Surprenant A (1996) P2X receptors in autonomic and sensory neurons. Semin Neurosci 8:217-223
34. 34. Surprenant A, Buell G, North RA (1995) P2X receptors bring new structure to ligand-gated ion channels. Trends Neurosci 18:224-229
35. 35. North RA (1995) (ed.) Ligand-and Voltage-gated Ion Channels. CRC Press, Roca Baton, Florida.
36. 36. Krishtal OA, Marchenko SM, Obukhov AG (1988) Cationic channels activated by extracellular ATP in rat sensory neurons. Neuroscience 3:995-1000
37. 37. Khakh B, Humphrey PPA, Surprenant A (1995) Electrophysiological properties of P2X purinoceptors in rat superior cervical, nodose and guinea-pig coeliac neurones. J Physiol 484:385-396
38. 38. Cully DF, Vassitalis DK, Liu KK, Paress PS, Van der Ploegh LH, Schaeffer JM, Arena JP (1994) Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans. Nature 371:707-711
39. 39. Akabas MH, Kaufmann C, Archdeacon P, Karlin A (1994) Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit. Neuron 13:919-927
40. 40. Unwin N (1995) Acetylcholine receptor channel imaged in the open state. Nature 373:37-43
41. 41. Hollmann M, Caron C, Heinemann S (1994) N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor. Neuron 13:1331-1343
42. 42. Wood MW, VanDongen HMA, VanDongen AMJ (1995) Structural conservation of ion conduction pathways in K channels and glutamate receptors. Proc Natl Acad Sci USA 92:4882-4886
43. 43. Lingueglia E, Champigny G, Lazdunski M, Barbry P (1995) Cloning of the amiloride-sensitive FMRFamide peptide gated sodium channel. Nature 378:730-732
44. 44. Canessa CM, Horisberger J-D, Rossier BC (1994) Epithelial sodium channel related to proteins involved in neurodegeneration. Nature 361:467-470
45. 45. Canessa CM, Schild L, Buell G, Thorens B, Gauthschl I, Horisberger J-D, Rossier BC (1994) Amiloride-sensitive sodium channel is made of three homologous subunits. Nature 367:463-467
46. 46. Hong K, Driscoll M (1994) A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans. Nature 367:470-472
47. 47. Huang M, Chalfie M (1994) Gene interactions affecting mechanosensory transduction in Caenorhabditics elegans. Nature 367:467-470
48. 48. Karlin A (1993) Structure of nicotinic acetylcholine receptors. Curr Opin Neurobiol 3:299-309
49. 49. Stern-Bach Y, Bettler B, Hartley M, Sheppard PO, O'Hara PJ, Heinemann SF (1994) Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid binding proteins. Neuron 13:1345-1357
50. 50. Koonin EV (1993) A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. Nucleic Acids Res 21:2541-2547
51. 51. Traut TW (1994) The functions and consensus motifs of nine types of peptide segments that form different types of nucleotide-binding sites. Eur J Biochem 22:9-19