Retinoid X receptor expression in the normal pituitary and clinically 'non-functioning' pituitary tumours

Clinical Endocrinology

Volumn 48, Issue 4, 1998, Pages 425-433

  Gittoes, N J L ^a,b   McCabe, C J ^a   Verhaeg, J ^a   Sheppard, M C ^a   Franklyn, J A ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; FOLLITROPIN; GROWTH HORMONE; LUTEINIZING HORMONE; PROLACTIN; RETINOID X RECEPTOR; THYROID HORMONE RECEPTOR; THYROTROPIN;

ADULT; ALPHA CHAIN; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOPHYSIS TUMOR; IMMUNOCYTOCHEMISTRY; MALE; NEGATIVE FEEDBACK; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE DIAGNOSIS; TRANSACTIVATION;

EID: 0031862223     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1998.00339.x     Document Type: Article

References (30)

1. Alexander, J.M., Swearingen, B., Tindall, G.T. & Klibanski, A. (1995) Human pituitary adenomas express endogenous inhibin subunit and follistatin messenger ribonucelic acids. Journal of Clinical Endocrinology and Metabolism, 80, 147-152.
2. Black, P.M., Hsu, D.W., Klibanski, A., Kliman, B., Jameson, J.L., Ridgway, E., Hedley-Whyte, E.T. & Zervas. N.T. (1987) Hormone production in clinically nonfunctioning pituitary adenomas. Journal of Neurosurgery. 66, 244-250.
3. 1 mediates 9-cis RA suppression of the TSH beta promoter in pituitary-derived cells. Thyroid, 6, S-63.
4. Chamba, A., Neuberger, J., Strain, A., Hopkins, J., Sheppard, M.C. & Franklyn, J.A. (1996) Expression and function of thyroid hormone receptor variants in normal and chronically diseased human liver. Journal of Clinical Endocrinology and Metabolism, 81, 360-367.
5. Chomczynski, P. & Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry. 162, 156-159.
6. Cohen, O., Flynn, T.R. & Wondisford, F.E. (1995) Ligand-dependent antagonism by retinoid X receptors of inhibitory thyroid hormone response elements. Journal of Biological Chemistry, 270, 13899-13905.
7. Cooke, T., Allegretto, E., Heyman, R. & Lamph, W. (1996) Direct submission to EMBL/GENBANK/DDBJ data banks. Accession number. P48443.
8. Gittoes, N.J.L., McCabe, C.J., Verhaeg, J., Sheppard, M.C. & Franklyn, J.A. (1997) Thyroid hormone and estrogen receptor expression in normal pituitary and 'non-functioning' tumours of the anterior pituitary. Journal of Clinical Endocrinology and Metabolism, 82, 1960-1967.
9. Glass, C.K. (1994) Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers. Review. Endocrine Review, 15, 391-407.
10. 1 mediates 9-cis-retinoic acid suppression of thyrotrophin-β promoter activity. Molecular Endocrinology. 11, 481-489.
11. Jameson, J.L., Klihanski, A., Black, P.M., Zervas, N.T., Lindell, C.M., Hsu, D.W., Ridgway, E.C. & Habener, J.F. (1987) Glycoprotein hormone genes are expressed in clinically nonfunctioning pituitary adenomas. Journal of Clinical Investigation, 80, 1472-1478.
12. Kindmark, A., Torma, H., Johansson, A., Ljunghall, S. & Melhus, H. (1993) Reverse transcription-polymerase chain reaction assay demonstrates that the 9-cis retinoic acid receptor alpha is expressed in human osteoblasts. Biochemical and Biophysical Research Communications. 192, 1367-1372.
13. 2) in negative regulation by thyroid hormone. In Proceedings of the 10th International Congress of Endocrinology. San Francisco, CA, Vol. 1, Endocrine Society Press, Bethesda. p. 122.
14. Leid, M., Kastner, P., Lyons, R., Nakshatri, H., Saunders, M., Zacharewski, T., Chen, J.Y., Staub, A., Gamier, J.M. & Mader, S. (1992) Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterdimerizes to bind target sequences efficiently. Cell, 68, 377-395.
15. Liu, Q. & Linney, E. (1993) The mouse retinoid-X receptor-gamma gene: genomic organization and evidence for functional isoforms. Molecular Endocrinology. 7, 651-658.
16. Mangelsdorf, D.J. & Borgmeyer, U., Heyman, R.A., Zhou, J.T., Ong, E.S., Oro, A.E., Kakizuka, A. & Evans, R.M. (1992) Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes & Development. 6, 329-344.
17. Mangelsdorf, D.J. & Evans, R.M. (1995) The RXR heterodimers and orphan receptors. Review. Cell, 83, 841-850.
18. Mangelsdorf, D.J., Ong, E.S., Dyck, J.A. & Evans, R.M. (1990) Nuclear receptor that identifies a novel retinoic acid response pathway. Nature, 345, 224-229.
19. Mano, H., Mori, R., Ozawa, T., Takeyama, K., Yoshizawu, Y., Kojima, R., Arao, Y., Masushige, S. & Kato , S. (1994) Positive and negative-regulation of retinoid X receptor gene expression by thyroid hormone in the rat. Transcriptional and post-transcriptional controls by thyroid hormone. Journal of Biological Chemistry, 269, 1591-1594.
20. Mano, H., Ozawa, T., Takeyama, K., Yoshizawa, Y., Kojima, R., Kato, S. & Masushige, S. (1993) Thyroid hormone affects the gene expression of retinoid X receptors in the adult rat. Biochemical and Biophysical Research Communiccitions, 191, 943-949.
21. Nakayama, H., Yokoi, H. & Fujita, J. (1992) Quantification of mRNA by non-radioactive RT-PCR and CCD imaging system. Nucleic Acids Research, 20, 4939.
22. Noonan, K.E., Beck, C., Holzmayer, T.A., Chin, J.E., Wunder, J.A., Andrulis, I.L., Gazdar, A.F., Willman, C.L., Griffith, B. & Von Hoff, D.D. (1990) Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumours by polymerase chain reaction. Proceedings of the National Academy of Sciences of the USA, 87, 7160-7164.
23. Oppenheim, D.S., Kana, A.R., Sangha, J.S. & Klibanski, A. (1990) Prevalence of alpha-subunit hypersecretion in patients with pituitary tumours: clinically nonfunctioning and somatroph adenomas. Journal of Clinical Endocrinology and Metabolism, 70, 859-864.
24. Reichrath, J., Munssinger, T., Kerber, A., Rochette-Egly, C., Chambon, P., Bahmer, F.A. & Baum, H.P. (1995) In situ detection of retinoid-X receptor expression in normal and psoriatic human skin. British Journal of Dermatology, 133, 168-175.
25. Salomon, R.N., Underwood, R., Doyle, M.V., Wang, A. & Libby, P. (1992) Increased apolipoprotein E and c-fms gene expression without elevated interleukin 1 or 6 mRNA levels indicates selective activation of macrophage functions in advanced human atheroma. Proceedings of the National Academy of Sciences of the USA. 89, 2814-2818.
26. Sugawara, A., Yen, P.M., Qi, Y., Lechan, R.M. & Chin, W.W. (1995) Isoform-specific retinoid-X receptor (RXR) antibodies detect differential expression of RXR proteins in the pituitary gland. Endocrinology, 136, 1766-1774.
27. Warnet, A., Porsova-Dutoit, I., Lahlou, N., Seret-Begue, D., Lajeunie, E., Chanson, P., Woimant, F., Lot, G., Guillausseau, P.J & Roger, M. (1994) Glycoprotein hormone alpha-subunit secretion in prolactinomas and in non-functioning adenomas: relation with the tumour size. Clinical Endocrinology, 41, 177-184.
28. Xu, X.C., Ro, J.Y., Lee, J.S., Shin, D.M., Hong, W.K. & Lotan, R. (1994) Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues. Cancer Research, 54, 3580-3587.
29. Yu, V.C., Delsert, C., Andersen, B., Holloway, J.M., Devary, O.V., Naar, A.M., Kim, S.Y., Boutin, J.M., Glass, C.K. & Rosenfeld, M.G. (1991) RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell, 67, 1251 -1266.
30. Zafar, M., Ezzat, S., Ramyar, L., Pan, N., Smyth, H.S. & Asa, S.L. (1995) Cell-specific expression of estrogen receptor in the human pituitary and its adenomas. Journal of Clinical Endocrinology and Metabolism, 80, 3621-3627.