Glucose-induced pulsatile insulin release from single islets at stable and oscillatory cytoplasmic Ca2+

American Journal of Physiology - Endocrinology and Metabolism

Volumn 274, Issue 5 37-5, 1998, Pages

  Bergsten, Peter ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Cytoplasmic calcium concentration; Endocrine pancreas; Insulin secretion; Islets of Langerhans; Oscillations

Indexed keywords

CALCIUM ION; GLUCOSE; INSULIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; GLUCOSE METABOLISM; INSULIN RELEASE; MOUSE; NONHUMAN; OSCILLATION; PANCREAS ISLET CELL; PRIORITY JOURNAL;

EID: 0031859130     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1998.274.5.e796     Document Type: Article

References (36)

1. Ashcroft, F. M., and P. Rorsman. Electrophysiology of the pancreatic β-cell. Prog. Biophys. Mol. Biol. 54: 87-143, 1989.
2. Ashcroft, S. J. H., J. M. Bassett, and P. J. Randle. Insulin secretion mechanisms and glucose metabolism in isolated islets. Diabetes 21, Suppl. 2: 538-545, 1972.
3. 2+ in pancreatic islets correspond to pulsatile insulin release. Am. J. Physiol. 268 (Endocrinol. Metab. 31): E282-E287, 1995.
4. 2+ and insulin release in glucose-stimulated pancreatic islets. J. Biol. Chem. 269: 8749-8753, 1994.
5. 2+. Am. J. Physiol. 255 (Endocrinol. Metab. 18): E422-E427, 1988.
6. Bergsten, P., and B. Hellman. Glucose inhibits insulin release when not promoting the entry of calcium into the β-cells. Biochem. Biophys. Res. Commun. 125: 875-881, 1984.
7. Bergsten, P., and B. Hellman. Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets. Diabetes 42: 670-674, 1993.
8. 2+ and the ATP/ADP ratio in permeabilized RINm5F insulinoma cells supplemented with a glycolyzing cell-free muscle extract. J. Biol. Chem. 263: 4254-4258, 1988.
9. Detimary, P., J. C. Jonas, and J. C. Henquin. Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets. J. Clin. Invest. 96: 1738-1745, 1995.
10. + channel activity provide evidence for inherent metabolic oscillations in pancreatic beta-cells. Biochem. Biophys. Res. Commun. 205: 880-885, 1994.
11. 2+-induced exocytosis in mouse pancreatic B-cells. J. Physiol. (Lond.) 503: 399-412, 1997.
12. 2+ concentration in an electrically excitable cell, the insulin-secreting pancreatic B-cell. J. Biol. Chem. 267: 20713-20720, 1992.
13. 2+ in the pancreatic β-cell. Biochem. Biophys. Res. Commun. 151: 1299-1304, 1988.
14. 2+. Cell Calcium 13: 219-226, 1992.
15. Grill, V., and E. Cerasi. Activation by glucose of adenyl cyclase in pancreatic islets of the rat. FEBS Lett. 33: 311-314, 1973.
16. Gromada, J., W. G. Ding, S. Barg, E. Renström, and P. Rorsman. Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors. Pflügers Arch. 434: 515-524, 1997.
17. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440-3450, 1985.
18. 2+ oscillations in clusters of pancreatic β-cells exposed to glucose. Cell Calcium 12: 229-240, 1991.
19. Gylfe, E., and B. Hellman. Calcium and the control of insulin secretion. In: Calcium and Cell Function, edited by W. Y. Cheung. San Diego, CA: Academic, 1986, vol. VI, p. 253-326.
20. 2+ signalling and insulin release. In: Frontiers of Insulin Secretion and Pancreatic B-Cell Research, edited by P. R. Flatt and S. Lenzen. London, UK: Smith-Gordon, 1994, p. 221-228.
21. Hiriart, M., and M. C. Ramirez-Medeles. Functional subpopulations of individual pancreatic B-cells in culture. Endocrinology 128: 3193-3198, 1991.
22. Kiekens, R., P. In't Veld, T. Mahler, F. Schutt, M. Van De Winkel, and D. Pipeleers. Differences in glucose recognition by individual rat pancreatic B cells are associated with intercellular differences in glucose-induced biosynthetic activity. J. Clin. Invest. 89: 117-125, 1992.
23. 2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets. J. Biol. Chem. 266: 9314-9319, 1991.
24. i oscillations by ketoisocaproate in single mouse pancreatic islets. Diabetes 44: 300-305, 1995.
25. Pipeleers, D. G. Physiological relevance of heterogeneity in the pancreatic beta-cell population. Diabetologia 37, Suppl. 2: S57-S64, 1994.
26. Porksen, N., S. Munn, J. Steers, S. Vore, J. Veldhuis, and P. C. Butler. Pulsatile insulin secretion accounts for 70% of total insulin secretion during fasting. Am. J. Physiol. 269 (Endocrinol. Metab. 32): E478-E488, 1995.
27. 2+ and secretion. EMBO J. 9: 53-60, 1990.
28. 2+ within electropermeabilized insulin-secreting cells (INS-1). Biochim. Biophys. Acta 1175: 107-113, 1992.
29. Stagner, J. I., E. Samols, and G. C. Weir. Sustained oscillations of insulin, glucagon, and somatostatin from the isolated canine pancreas during exposure to a constant glucose concentration. J. Clin. Invest. 65: 939-942, 1980.
30. Tornheim, K. Are metabolic oscillations responsible for the normal oscillatory insulin secretion? Diabetes 46: 1375-1380, 1997.
31. 2+ concentration resembling bursting electrical activity in single mouse islets of Langerhans. FEBS Lett. 259: 19-23, 1989.
32. Van De Winkel, M., and D. Pipeleers. Autofluorescence-activated cell sorting of pancreatic islet cells: purification of insulin-containing B-cells according to glucose-induced changes in cellular redox state. Biochem. Biophys. Res. Commun. 114: 835-842, 1983.
33. Van Schravendijk, C. F. H., R. Kiekens, and D. G. Pipeleers. Pancreatic beta cell heterogeneity in glucose-induced insulin secretion. J. Biol. Chem. 267: 21344-21348, 1992.
34. 2+. J. Clin. Invest. 100: 2547-2551, 1997.
35. 2+. J. Clin. Invest. 97: 1860-1863, 1996.
36. Wollheim, C. B., and G. W. G. Sharp. Regulation of insulin release by calcium. Physiol. Rev. 61: 914-973, 1981.