Fission yeast cdc24+ encodes a novel replication factor required for chromosome integrity

Genetics

Volumn 149, Issue 3, 1998, Pages 1221-1233

  Gould, Kathleen L ^a,c   Burns, C Geoffrey ^a   Feoktistova, Anna ^a   Hu, Ching Pei ^a   Pasion, Sally G ^b   Forsburg, Susan L ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c B2309 MCN ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CYCLE; DNA REPLICATION; GENE ISOLATION; GENETIC CONSERVATION; GENETIC STABILITY; NONHUMAN; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE;

ALLELES; AMINO ACID SEQUENCE; BASE SEQUENCE; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; FUNGAL PROTEINS; GENETIC COMPLEMENTATION TEST; GENOTYPE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INTRONS; MOLECULAR SEQUENCE DATA; PROTO-ONCOGENE PROTEINS; RECOMBINATION, GENETIC; REPRESSOR PROTEINS; RESTRICTION MAPPING; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE;

FUNGI; MYXOGASTRIA; SCHIZOSACCHAROMYCES POMBE;

EID: 0031855473     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. ALTSCHUL, S. F., W. GISH, W. MILLER, E. W. MYERS and D. J. LIPMAN, 1990 Basic local alignment search tool. J. Mol. Biol. 215: 403-410.
2. BARBET, N., W. J. MURIEL, and A. M. CARR, 1992 Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe. Gene 114: 59-66.
3. BIERNE, H., and B. MICHEL, 1994 When replication forks stop. Mol. Microbiol. 13: 17-23.
4. BUDD, M. E., and J. L. CAMPBELL, 1993 DNA polymerases δ and ε are required for chromosomal replication in Saccharomyces cerevisiae. Mol. Cell. Biol. 13: 496-505.
5. BUDD, M. E., and J. L. CAMPBELL, 1995 A yeast gene required for DNA replication encodes a protein with homology to DNA helicases. Proc. Natl. Acad. Sci. USA 92: 7642-7646.
6. BUDD, M. E., and J. L. CAMPBELL, 1997 A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function. Mol. Cell. Biol. 17: 2136-2142.
7. BUDD, M. E., W.-C. CHOE and J. L. CAMPBELL, 1995 DNA2 encodes a DNA helicase essential for replication of eukaryotic chromosomes. J. Biol. Chem. 270: 26766-26769.
8. BURGERS, P. M., 1996 Enzymology of the replication fork, pp. 1-28 in Eukaryotic DNA Replication, edited by J. J. BLOW. Oxford University Press, Oxford.
9. CARPENTER, P. B., P. R. MUELLER and W. G. DUNPHY, 1996 Role for a Xenopus Orc2-related protein in controlling DNA replication. Nature 379: 357-360.
10. CARR, A. M., and M. F. HOEKSTRA, 1995 The cellular response to DNA damage. Trends Cell Biol. 5: 32-40.
11. + belongs to a family of proteins involved in an early step of chromosome replication. Nucleic. Acids Res. 20: 5571-5577.
12. D'INCALCI, M., 1993 DNA topoisomerase inhibitors. Curr. Opin. Oncol. 5: 1023-1028.
13. + encodes DNA polymerase ε and is required for chromosomal replicaton but not for the S phase checkpoint. Proc. Natl. Acad. Sci. USA 94: 12,491-12,496.
14. D'URSO, G., B. GRALLERT and P. NURSE, 1995 DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast. J. Cell Sci. 108: 3109-3118.
15. DAMAGNEZ, V., J. TILLIT, A.-M. RECONDO and G. BALDACCI, 1991 The POL1 gene from fission yeast, Schizosaccharomyces pombe, shows conserved amino acid blocks specific for eukaryotic DNA polymerase alpha. Mol. Gen. Genet. 226: 182-189.
16. DONOVAN, S., J. HARWOOD, L. S. DRURY and J. F. X. DIFFLEY, 1997 Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast. Proc. Natl. Acad. Sci. USA 94: 5611-5616.
17. + of the fission yeast Schizosaccharomyces pombe encode the large and small subunits of ribonucleotide reductase. Mol. Gen. Genet. 238: 241-251.
18. FIKES, J. D., D. M. BECKER, F. WINSTON and L. GUARENTE, 1990 Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Nature 346: 291-294.
19. FIORENTINO, D. F., and G. R. CRABTREE, 1997 Characterization of Saccharomyces cerevisiae dna2 mutants suggests a role for the helicase late in S phase. Mol. Biol. Cell 8: 2519-2537.
20. FORSBURG, S. L., 1996 Regulation of S phase in the fission yeast Schizosaccharomyces pombe, pp. 197-228 in Eukaryotic DNA Replication, edited by J. J. BLOW. Oxford University Press, Oxford.
21. + gene encodes a member of the MCM family of replication proteins. J. Cell Sci. 107: 2779-2788.
22. FRANCESCONI, S., A.-M. DE RECONDO and G. BALDACCI, 1995 DNA polymerase delta is required for the replication feedback control of cell cycle progression in Schizosaccharomyces pombe. Mol. Gen. Genet. 246: 561-569.
23. FRANCESCONI, S., H. PARK and T. S. F. WANG, 1993 Fission yeast with DNA polymerase delta temperature sensitive alleles exhibits cell division cycle phenotype. Nucleic. Acids Res. 21: 3821-3828.
24. GORBALENYA, A. E., E. V. KOONIN, A. P. DONCHENKO and V. M. BLINOV, 1989 Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res. 17: 4713-4730.
25. GRALLERT, B., and P. NURSE, 1996 The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase. Genes Dev. 10: 2644-2654.
26. HOHEISEL, J. D., E. MAIER, R. MOTT, L. MCCARTHY, A. V. GRIGORIEV et al., 1993 High-resolution cosmid and P1 maps spanning the 14 Mbp genome of the fission yeast Schizosaccharomyces pombe. Cell 73: 109-120.
27. + required for G2-M transition in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 231: 401-410.
28. IINO, Y., and M. YAMAMOTO, 1997 The Schizosaccharomyces pombe cdc6 gene encodes the catalytic subunit of DNA polymerase delta. Mol. Gen. Genet. 254: 93-97.
29. JALLEPALLI, P. V., and T. J. KELLY, 1996 rum1 and cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe. Genes Dev. 10: 541-552.
30. JOHNSTON, L., D. BARKER and P. NURSE, 1986 Molecular cloning of the Schizosaccharomyces pombe DNA ligase gene cdc17 and an associated sequence promoting high frequency plasmid transformation. Gene 41: 321-325.
31. + gene product couples S phase to START and mitosis. Cell 74: 371-382.
32. KOMINAMI, K., and T. TODA, 1997 Fission yeast WD-repeat protein Pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18. Genes Dev. 11: 1548-1560.
33. KUO, C.-L., N.-H. HUANG and J. L. CAMPBELL, 1983 Isolation of yeast DNA replication mutants in permeabilized cells. Proc. Natl. Acad. Sci. USA 80: 6465-6469.
34. LEATHERWOOD, J., A. LOPEZGIRONA and P. RUSSELL, 1996 Interaction of cdc2 and cdc18 with a fission yeast Orc2-like protein. Nature 379: 360-363.
35. +. Nature 355: 449-452.
36. LUNDGREN, K., N. WALWORTH, R. BOOHER, M. DEMBSKI, M. KIRSCHNER et al., 1991 mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell 64: 1111-1122.
37. MACNEILL, S. A., S. MORENO, N. REYNOLDS, P. NURSE and P. A. FANTES, 1996 The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27. EMBO J. 15: 4613-4628.
38. MACNEILL, S. A., and P. NURSE, 1997 Cell cycle control in fission yeast, pp. 697-763 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Cell Cycle and Cell Biology, edited by J. PRINGLE, J. BROACH and E. W. JONES. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
39. MAIORANO, D., G. BLOM VAN ASSENDELFT and S. E. KEARSEY, 1996 Fission yeast cdc21, a member of the MCM protein family, is required for onset of S phase and located in the nucleus throughout the cell cycle. EMBO J. 15: 861-872.
40. + , a Schizosaccharomyces pombe gene related to Saccharomyces cerevisiae CDC7, is required for chromosomal replication. EMBO J. 14: 3094-3104.
41. MAUNDRELL, K., 1990 nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine. J. Biol. Chem. 265: 10857-10864.
42. MICHEL, B., S. D. EHRLICH and M. UZEST, 1997 DNA double strand breaks caused by replication arrest. EMBO J. 16: 430-438.
43. MORENO, S., A. KLAR and P. NURSE, 1991 Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194: 795-823.
44. MUZI-FALCONI, M., and T. J. KELLY, 1995 Orp1, a member of the cdc18/cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex. Proc. Natl. Acad. Sci. USA 92: 12475-12479.
45. NASMYTH, K., and P. NURSE, 1981 Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 182: 119-124.
46. NURSE, P., and Y. BISSETT, 1981 Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast. Nature 292: 558-560.
47. OHI, R., A. FEOKTISTOVA and K. L. GOULD, 1996 Construction of vectors and a genomic library for use with his3-deficient strains of Schizosaccharomyces pombe. Gene 174: 315-318.
48. OKISHIO, N., Y. ADACHI and M. YANAGIDA, 1996 Fission yeast nda1 and nda4, MCM homologs required for DNA replication, are constitutively nuclear proteins. J. Cell Sci. 109: 319-326.
49. PALITTI, F., 1993 Mechanism of induction of chromosomal aberrations by inhibitors of DNA topoisomerases. Environ. Mol. Mutagen. 22: 275-277.
50. PARKER, A. E., R. K. CLYNE, A. M. CARR and T. J. KELLY, 1997 The Schizosaccharomyces pombe rad11(+) gene encodes the large subunit of replication protein A. Mol. Cell. Biol. 17: 2381-2390.
51. PIGNEDE, G., D. BOUVIER, A. M. DERECONDO and G. BALDACCI, 1991 Characterization of the pol3 gene product from Schizosaccharomyces pombe indicates interspecies conservation of the catalytic subunit of DNA polymerase delta. J. Mol. Biol. 222: 209-218.
52. PRENTICE, H. L., 1992 High efficiency transformation of Schizosaccharomyces pombe by electroporation. Nucleic Acids Res. 20: 621.
53. ROMANOWSKI, P., M. A. MADINE, A. ROWLES, J. J. BLOW and R. A. LASKEY, 1996 The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin. Curr. Biol. 6: 1416-1425.
54. +. Cell 74: 383-393.
55. SANTOCANALE, C., and J. F. X. DIFFLEY, 1996 ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae. EMBO J. 15: 6671-6679.
56. SAZER, S., and S. W. SHERWOOD, 1990 Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast. J. Cell Sci. 97: 509-516.
57. SCLAFANI, R. A., and A. L. JACKSON, 1994 Cdc7 protein-kinase for DNA metabolism comes of age. Mol. Microbiol. 11: 805-810.
58. SINGH, J., and A. J. S. KLAR, 1993 DNA polymerase alpha is essential for mating type switching in fission yeast. Nature 361: 271-273.
59. STEWART, E., and T. ENOCH, 1996 S-phase and Dna-damage checkpoints - a tale of two yeasts. Curr. Opin. Cell. Biol. 8: 781-787.
60. WASEEM, N. H., K. LABIB, P. NURSE and D. P. LANE, 1992 Isolation and analysis of the fission yeast gene encoding polymerase δ accessory protein PCNA. EMBO J. 11: 5111-5120.
61. ZHANG, M. Q., and T. G. MARR, 1994 Fission yeast gene structure and recognition. Nucleic Acids Res. 22: 1750-1759.