메뉴 건너뛰기




Volumn 5, Issue 5, 1998, Pages 1025-1033

Differential effects of estradiol and its analogs on cyclin D1 and CDK4 expression in estrogen receptor positive MCF-7 and estrogen receptor-transfected MCF-10AEwt5 cells

Author keywords

CDK4; Cyclin D1; Estradiol; MCF 7 cells

Indexed keywords

2 HYDROXYESTRATRIEN 17BETA OL; 3 HYDROXYESTRATRIENE; 4 HYDROXYESTRATRIEN 17BETA OL; CYCLIN D1; CYCLIN DEPENDENT KINASE; ESTRADIOL; ESTRADIOL DERIVATIVE; ESTRATRIEN 17BETA OL; ESTROGEN RECEPTOR; UNCLASSIFIED DRUG;

EID: 0031854959     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.5.5.1025     Document Type: Article
Times cited : (14)

References (63)
  • 1
    • 0027450031 scopus 로고
    • Hormonal chemoprevention of cancer in women
    • Henderson BE, Ross RK and Pike MC: Hormonal chemoprevention of cancer in women. Science 259: 633-638, 1993.
    • (1993) Science , vol.259 , pp. 633-638
    • Henderson, B.E.1    Ross, R.K.2    Pike, M.C.3
  • 4
    • 0030867507 scopus 로고    scopus 로고
    • Hormone replacement therapy and the risk of breast lesions that predispose to cancer
    • Cahn MD, Tran T, Theur CP and Butler JA: Hormone replacement therapy and the risk of breast lesions that predispose to cancer. Am Surg 63: 858-860, 1997.
    • (1997) Am Surg , vol.63 , pp. 858-860
    • Cahn, M.D.1    Tran, T.2    Theur, C.P.3    Butler, J.A.4
  • 7
    • 0030071445 scopus 로고    scopus 로고
    • Tripartite steroid hormone receptor pharmacology; interaction with multiple effector sites as a basis for the cell-and promoter-specific action of these hormones
    • Katzenellenbogen JA, O'Malley BW and Katzenellenbogen BS: Tripartite steroid hormone receptor pharmacology; interaction with multiple effector sites as a basis for the cell-and promoter-specific action of these hormones. Mol Endocrinol 10: 119-131, 1996.
    • (1996) Mol Endocrinol , vol.10 , pp. 119-131
    • Katzenellenbogen, J.A.1    O'Malley, B.W.2    Katzenellenbogen, B.S.3
  • 8
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β
    • Kuiper G, Carlsson B, Grandien K, Enmark E, Hagglad J, Nilsson S and Gustafsson J-A: Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 138: 863-870, 1997.
    • (1997) Endocrinology , vol.138 , pp. 863-870
    • Kuiper, G.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Hagglad, J.5    Nilsson, S.6    Gustafsson, J.-A.7
  • 9
    • 0024323891 scopus 로고
    • Direct effects of estrogen on c-fos and c-myc protooncogene expression and cellular proliferation in human breast cancer cells
    • Van der Burg B, van Selm-Miltenburg AJ, De Laat SW and van Zoelen EJ: Direct effects of estrogen on c-fos and c-myc protooncogene expression and cellular proliferation in human breast cancer cells. Mol Cell Endocrinol 64: 223-228, 1989.
    • (1989) Mol Cell Endocrinol , vol.64 , pp. 223-228
    • Van Der Burg, B.1    Van Selm-Miltenburg, A.J.2    De Laat, S.W.3    Van Zoelen, E.J.4
  • 11
    • 0023462398 scopus 로고
    • Estrogen and oncogene mediated growth regulation of human breast cancer cells
    • Kasid A and Lippman ME: Estrogen and oncogene mediated growth regulation of human breast cancer cells. J Steroid Biochem 27: 465-470, 1987.
    • (1987) J Steroid Biochem , vol.27 , pp. 465-470
    • Kasid, A.1    Lippman, M.E.2
  • 12
    • 0028265460 scopus 로고
    • Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: Therapeutic implications
    • Thomas T and Thomas TJ: Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications. Breast Cancer Res Treat 29: 189-201, 1993.
    • (1993) Breast Cancer Res Treat , vol.29 , pp. 189-201
    • Thomas, T.1    Thomas, T.J.2
  • 13
    • 0029781653 scopus 로고    scopus 로고
    • Structure-activity correlations of S-adenosylmethionine decarboxylase inhibitors on the growth of MCF-7 breast cancer cells
    • Thomas T, Faaland CA, Adhikarakunnathu S and Thomas TJ: Structure-activity correlations of S-adenosylmethionine decarboxylase inhibitors on the growth of MCF-7 breast cancer cells. Breast Cancer Res Treat 39: 293-306, 1996.
    • (1996) Breast Cancer Res Treat , vol.39 , pp. 293-306
    • Thomas, T.1    Faaland, C.A.2    Adhikarakunnathu, S.3    Thomas, T.J.4
  • 14
    • 0030964233 scopus 로고    scopus 로고
    • Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens
    • Wilken NRC, Prall OWJ, Musgrove EA and Sutherland RL: Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens. Clin Cancer Res 3: 849-854, 1997.
    • (1997) Clin Cancer Res , vol.3 , pp. 849-854
    • Wilken, N.R.C.1    Prall, O.W.J.2    Musgrove, E.A.3    Sutherland, R.L.4
  • 15
    • 0030012189 scopus 로고    scopus 로고
    • Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells
    • Foster JS and Wimalasena J: Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells. Mol Endocrinol 10: 488-498, 1996.
    • (1996) Mol Endocrinol , vol.10 , pp. 488-498
    • Foster, J.S.1    Wimalasena, J.2
  • 16
    • 0026693966 scopus 로고
    • Animal cell cycles and their control
    • Norbury C and Nurse P: Animal cell cycles and their control. Annu Rev Biochem 61: 441-470, 1992.
    • (1992) Annu Rev Biochem , vol.61 , pp. 441-470
    • Norbury, C.1    Nurse, P.2
  • 18
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ: Cancer cell cycles. Science 274: 1672-1677, 1996.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 20
    • 0029910364 scopus 로고    scopus 로고
    • Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 check-point
    • Lukas J, Bartkova J and Bartek J: Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 check-point. Mol Cell Biol 16: 6917-6925, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 6917-6925
    • Lukas, J.1    Bartkova, J.2    Bartek, J.3
  • 23
    • 0028889751 scopus 로고
    • Mice lacking cyclin D1 are small and show defects in eye and mammary gland development
    • Fant V, Stamp G, Andrews A, Rosewell I and Dickson C: Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. Genes Dev 9: 2364-2372, 1995.
    • (1995) Genes Dev , vol.9 , pp. 2364-2372
    • Fant, V.1    Stamp, G.2    Andrews, A.3    Rosewell, I.4    Dickson, C.5
  • 24
    • 0030888284 scopus 로고    scopus 로고
    • Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2
    • Prall OWJ, Sarcevic B, Musgrove EA, Watts CKW and Sutherland RL: Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2. J Biol Chem 272: 10882-10894, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 10882-10894
    • Prall, O.W.J.1    Sarcevic, B.2    Musgrove, E.A.3    Watts, C.K.W.4    Sutherland, R.L.5
  • 25
    • 0029665447 scopus 로고    scopus 로고
    • 17β-estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(l)-arrested human breast cancer cells
    • Altucci L, Addeo R, Cicatiello L, Dauvois S, Parker MG, Truss M, Beato M, Sica V, Bresciani F and Weisz A: 17β-estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(l)-arrested human breast cancer cells. Oncogene 12: 2315-2324, 1996.
    • (1996) Oncogene , vol.12 , pp. 2315-2324
    • Altucci, L.1    Addeo, R.2    Cicatiello, L.3    Dauvois, S.4    Parker, M.G.5    Truss, M.6    Beato, M.7    Sica, V.8    Bresciani, F.9    Weisz, A.10
  • 28
    • 0027486303 scopus 로고
    • Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases
    • Geng Y and Weinberg RA: Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases. Proc Natl Acad Sci USA 90: 10315-10319, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10315-10319
    • Geng, Y.1    Weinberg, R.A.2
  • 29
    • 0030861110 scopus 로고    scopus 로고
    • Mutual requirement of CDK4 and Myc in malignant transformation: Evidence for cyclin D1/CDK4 and p16/ INK4A as upstream regulators of Myc
    • Haas K, Staller P, Geisen C, Bartek J, Eilers M and Moroy T: Mutual requirement of CDK4 and Myc in malignant transformation: evidence for cyclin D1/CDK4 and p16/ INK4A as upstream regulators of Myc. Oncogene 15: 179-192, 1997.
    • (1997) Oncogene , vol.15 , pp. 179-192
    • Haas, K.1    Staller, P.2    Geisen, C.3    Bartek, J.4    Eilers, M.5    Moroy, T.6
  • 32
    • 0030833331 scopus 로고    scopus 로고
    • Reproductive health in humans and wildlife: Are adverse trends associated with environmental chemical exposure?
    • Harrison PT, Holmes P and Humfrey CD: Reproductive health in humans and wildlife: are adverse trends associated with environmental chemical exposure? Sci Total Environ 205: 97-106, 1997.
    • (1997) Sci Total Environ , vol.205 , pp. 97-106
    • Harrison, P.T.1    Holmes, P.2    Humfrey, C.D.3
  • 33
    • 0030905564 scopus 로고    scopus 로고
    • Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins
    • Danzo BJ: Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins. Environ Health Perspect 105: 294-301, 1997.
    • (1997) Environ Health Perspect , vol.105 , pp. 294-301
    • Danzo, B.J.1
  • 34
    • 0030954438 scopus 로고    scopus 로고
    • In vitro synergistic interaction of alligator and human estrogen receptors with combinations of environmental chemicals
    • Arnold SF, Vonier PM, Collins BM, Klotz DM, Guillette LJ Jr and McLachlan JA: In vitro synergistic interaction of alligator and human estrogen receptors with combinations of environmental chemicals. Environ Health Perspect 105 (Suppl 3): 615-618, 1997.
    • (1997) Environ Health Perspect , vol.105 , Issue.3 SUPPL. , pp. 615-618
    • Arnold, S.F.1    Vonier, P.M.2    Collins, B.M.3    Klotz, D.M.4    Guillette Jr., L.J.5    McLachlan, J.A.6
  • 37
    • 0027530041 scopus 로고
    • Blood levels of organochlorine residues and risk of breast cancer
    • Wolff MS, Toniolo PG, Lee EW and Dubin RN: Blood levels of organochlorine residues and risk of breast cancer. J Natl Cancer Inst 85: 648-652, 1993.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 648-652
    • Wolff, M.S.1    Toniolo, P.G.2    Lee, E.W.3    Dubin, R.N.4
  • 38
    • 0028267949 scopus 로고
    • Breast cancer and serum organochlorines: A prospective study among White, Black, and Asian women
    • Krieger N, Wolff MS, Hiatt RA, Rivera M, Vogelman J and Orentreich N: Breast cancer and serum organochlorines: a prospective study among White, Black, and Asian women. J Natl Cancer Inst 86: 589-599, 1994.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 589-599
    • Krieger, N.1    Wolff, M.S.2    Hiatt, R.A.3    Rivera, M.4    Vogelman, J.5    Orentreich, N.6
  • 39
    • 0027169989 scopus 로고
    • Influence of estrogen structure on nuclear binding and progesterone receptor induction by the receptor complex
    • Van der Kurr JA, Wiese T and Brooks SC: Influence of estrogen structure on nuclear binding and progesterone receptor induction by the receptor complex. Biochemistry 32: 7002-7008, 1993.
    • (1993) Biochemistry , vol.32 , pp. 7002-7008
    • Van Der Kurr, J.A.1    Wiese, T.2    Brooks, S.C.3
  • 40
    • 0027261504 scopus 로고
    • Effects of estradiol-17β analogues on activation of estrogen response element regulated chloramphenicol acetyltransferase expression
    • Van der Kuur JA, Hafner MS, Christman JK and Brooks SC: Effects of estradiol-17β analogues on activation of estrogen response element regulated chloramphenicol acetyltransferase expression. Biochemistry 32: 7016-7021, 1993.
    • (1993) Biochemistry , vol.32 , pp. 7016-7021
    • Van Der Kuur, J.A.1    Hafner, M.S.2    Christman, J.K.3    Brooks, S.C.4
  • 41
    • 0027204135 scopus 로고
    • Differential induction of pS2 and cathepsin D mRNAs by structurally altered estrogens
    • Pilat MJ, Hafner MS, Kral LG and Brooks SC: Differential induction of pS2 and cathepsin D mRNAs by structurally altered estrogens. Biochemistry 32: 7009-7015, 1993.
    • (1993) Biochemistry , vol.32 , pp. 7009-7015
    • Pilat, M.J.1    Hafner, M.S.2    Kral, L.G.3    Brooks, S.C.4
  • 42
    • 0024422821 scopus 로고
    • Regulation of ornithine decarboxylase gene expression in MCF-7 breast cancer cells by antiestrogens
    • Thomas T, Trend B, Butterfield JR, Jänne OA and Kiang DT: Regulation of ornithine decarboxylase gene expression in MCF-7 breast cancer cells by antiestrogens. Cancer Res 49: 5852-5857, 1989.
    • (1989) Cancer Res , vol.49 , pp. 5852-5857
    • Thomas, T.1    Trend, B.2    Butterfield, J.R.3    Jänne, O.A.4    Kiang, D.T.5
  • 43
    • 0031973862 scopus 로고    scopus 로고
    • Induction of p21(CIP1/WAF1/SID1) by estradiol in a breast epithelial cell line transfected with the recombinant estrogen receptor gene: A possible mechanism for a negative regulatory role of estradiol
    • Thomas TJ, Faaland CA, Adhikarakunnathu S, Watkins L and Thomas T: Induction of p21(CIP1/WAF1/SID1) by estradiol in a breast epithelial cell line transfected with the recombinant estrogen receptor gene: a possible mechanism for a negative regulatory role of estradiol. Breast Cancer Res Treat 47: 181-193, 1998.
    • (1998) Breast Cancer Res Treat , vol.47 , pp. 181-193
    • Thomas, T.J.1    Faaland, C.A.2    Adhikarakunnathu, S.3    Watkins, L.4    Thomas, T.5
  • 44
    • 0028205818 scopus 로고
    • Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells
    • Thomas T and Thomas TJ: Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells. Cancer Res 54: 1077-1084, 1994.
    • (1994) Cancer Res , vol.54 , pp. 1077-1084
    • Thomas, T.1    Thomas, T.J.2
  • 45
    • 0031027116 scopus 로고    scopus 로고
    • Anti-tumor effects of a bis(benzyl)spermine analog on MCF-7 breast cancer cells in culture and in nude mice xenografts
    • Thomas TJ, Shah N, Faaland CA, Gallo MA, Yurkow E, Satyaswaroop PC and Thomas T: Anti-tumor effects of a bis(benzyl)spermine analog on MCF-7 breast cancer cells in culture and in nude mice xenografts. Oncol Rep 4: 5-13, 1997.
    • (1997) Oncol Rep , vol.4 , pp. 5-13
    • Thomas, T.J.1    Shah, N.2    Faaland, C.A.3    Gallo, M.A.4    Yurkow, E.5    Satyaswaroop, P.C.6    Thomas, T.7
  • 46
    • 0022501550 scopus 로고
    • Ribonuclease-induced transformation of progesterone receptor from rabbit uterus
    • Thomas T and Klang DT: Ribonuclease-induced transformation of progesterone receptor from rabbit uterus. J Steroid Biochem 24: 505-511, 1986.
    • (1986) J Steroid Biochem , vol.24 , pp. 505-511
    • Thomas, T.1    Klang, D.T.2
  • 47
    • 0021249233 scopus 로고
    • Characterization of nuclear estradiol receptors released by micrococcal nuclease and DNAse I
    • Thomas T and Leung BS: Characterization of nuclear estradiol receptors released by micrococcal nuclease and DNAse I. J Steroid Biochem 21: 35-42, 1984.
    • (1984) J Steroid Biochem , vol.21 , pp. 35-42
    • Thomas, T.1    Leung, B.S.2
  • 48
    • 0023136544 scopus 로고
    • Structural alterations and stabilization of rabbit uterine estrogen receptors by natural polyamines
    • Thomas T and Kiang DT: Structural alterations and stabilization of rabbit uterine estrogen receptors by natural polyamines. Cancer Res 47: 1799-1804, 1987.
    • (1987) Cancer Res , vol.47 , pp. 1799-1804
    • Thomas, T.1    Kiang, D.T.2
  • 49
    • 0027484427 scopus 로고
    • Estrogen inhibits the growth of estrogen receptor-negative, but not estrogen receptor-positive, human mammary epithelial cells expressing a recombinant estrogen receptor
    • Zajchowski DA, Sager R and Webster L: Estrogen inhibits the growth of estrogen receptor-negative, but not estrogen receptor-positive, human mammary epithelial cells expressing a recombinant estrogen receptor. Cancer Res 53: 5004-5011, 1993.
    • (1993) Cancer Res , vol.53 , pp. 5004-5011
    • Zajchowski, D.A.1    Sager, R.2    Webster, L.3
  • 50
    • 0026520381 scopus 로고
    • Growth regulation of estrogen receptor-negative breast cancer cells transfected with complimentary DMAs for estrogen receptor
    • Jiang S-Y and Jordan VC: Growth regulation of estrogen receptor-negative breast cancer cells transfected with complimentary DMAs for estrogen receptor. J Natl Cancer Inst 84: 580-591, 1992.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 580-591
    • Jiang, S.-Y.1    Jordan, V.C.2
  • 51
    • 0028108451 scopus 로고
    • Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle
    • Musgrove EA, Lee CS, Buckley MF and Sutherland RL: Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle. Proc Natl Acad Sci USA 91: 8022-8026, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8022-8026
    • Musgrove, E.A.1    Lee, C.S.2    Buckley, M.F.3    Sutherland, R.L.4
  • 52
    • 0025064122 scopus 로고
    • Estradiol and estrogen receptor-dependent stabilization of a minivitellogenin mRNA lacking 5,100 nucleotides of coding sequence
    • Nielsen DA and Shapiro DJ: Estradiol and estrogen receptor-dependent stabilization of a minivitellogenin mRNA lacking 5,100 nucleotides of coding sequence. Mol Cell Biol 10: 371-376, 1990.
    • (1990) Mol Cell Biol , vol.10 , pp. 371-376
    • Nielsen, D.A.1    Shapiro, D.J.2
  • 53
    • 0030753755 scopus 로고    scopus 로고
    • Rapid membrane effects of steroids in neuroblastoma cells: Effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription
    • Watters JJ, Campbell JS, Cunningham MJ, Krebs EG and Dorsa DM: Rapid membrane effects of steroids in neuroblastoma cells: effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription. Endocrinology 138: 4030-4033, 1997.
    • (1997) Endocrinology , vol.138 , pp. 4030-4033
    • Watters, J.J.1    Campbell, J.S.2    Cunningham, M.J.3    Krebs, E.G.4    Dorsa, D.M.5
  • 54
    • 0026450958 scopus 로고
    • Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells
    • Garcia M, Derocq D, Freiss G and Rochefort H: Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells. Proc Natl Acad Sci USA 89: 11538-11542, 1992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11538-11542
    • Garcia, M.1    Derocq, D.2    Freiss, G.3    Rochefort, H.4
  • 55
    • 0025013048 scopus 로고
    • Construction of cell lines that express high levels of the human estrogen receptor that are killed by estrogens
    • Kushner PJ, Hort E, Shine J, Baxter JD and Greene GL: Construction of cell lines that express high levels of the human estrogen receptor that are killed by estrogens. Mol Endocrinol 4: 1465-1473, 1990.
    • (1990) Mol Endocrinol , vol.4 , pp. 1465-1473
    • Kushner, P.J.1    Hort, E.2    Shine, J.3    Baxter, J.D.4    Greene, G.L.5
  • 56
    • 0030663347 scopus 로고    scopus 로고
    • 17β-estradiol-mediated growth inhibition of MDA-MB-468 cells stably transfected with the estrogen receptor: Cell cycle effects
    • Wang W, Smith R III, Burghardt R and Safe SH: 17β-estradiol-mediated growth inhibition of MDA-MB-468 cells stably transfected with the estrogen receptor: cell cycle effects. Mol Cell Endocrinol 133: 49-62, 1997.
    • (1997) Mol Cell Endocrinol , vol.133 , pp. 49-62
    • Wang, W.1    Smith III, R.2    Burghardt, R.3    Safe, S.H.4
  • 57
    • 0027495966 scopus 로고
    • Ligand-mediated modulation of estrogen receptor conformation by estradiol analogs
    • Schwartz JA and Skafar DF: Ligand-mediated modulation of estrogen receptor conformation by estradiol analogs. Biochemistry 32: 10109-10115, 1993.
    • (1993) Biochemistry , vol.32 , pp. 10109-10115
    • Schwartz, J.A.1    Skafar, D.F.2
  • 58
    • 0028881966 scopus 로고
    • Relationship between estrogen structure and conformational changes in estrogen receptor/DNA complexes
    • Christman JK, Nehls S, Polin L and Brooks SC: Relationship between estrogen structure and conformational changes in estrogen receptor/DNA complexes. J Steroid Biochem Mol Biol 54: 201-210, 1995.
    • (1995) J Steroid Biochem Mol Biol , vol.54 , pp. 201-210
    • Christman, J.K.1    Nehls, S.2    Polin, L.3    Brooks, S.C.4
  • 59
    • 0031059270 scopus 로고    scopus 로고
    • The estradiol pharmacophore ligand structure-estrogen receptor binding affinity relationships and a model for receptor binding site
    • Anstead GM, Carlson KE and Katzenellenbogen JA: The estradiol pharmacophore ligand structure-estrogen receptor binding affinity relationships and a model for receptor binding site. Steroids 62: 268-303, 1997.
    • (1997) Steroids , vol.62 , pp. 268-303
    • Anstead, G.M.1    Carlson, K.E.2    Katzenellenbogen, J.A.3
  • 61
    • 0023689751 scopus 로고
    • The mechanism of action of steroid antagonists: Insights from crystallographic studies
    • Duax WL, Griffin JF, Weeks CM and Wawrzak Z: The mechanism of action of steroid antagonists: insights from crystallographic studies. J Steroid Biochem 31: 481-492, 1988.
    • (1988) J Steroid Biochem , vol.31 , pp. 481-492
    • Duax, W.L.1    Griffin, J.F.2    Weeks, C.M.3    Wawrzak, Z.4
  • 62
    • 0030660115 scopus 로고    scopus 로고
    • Induction of the estrogen specific mitogenic response of MCF-7 cells by selected analogue of estradiol-17β: A 3D QSAR study
    • Wiese TE, Polin LA, Palomino E and Brooks SC: Induction of the estrogen specific mitogenic response of MCF-7 cells by selected analogue of estradiol-17β: a 3D QSAR study. J Med Chem 40: 3659-3669, 1997.
    • (1997) J Med Chem , vol.40 , pp. 3659-3669
    • Wiese, T.E.1    Polin, L.A.2    Palomino, E.3    Brooks, S.C.4
  • 63
    • 0030685806 scopus 로고    scopus 로고
    • Molecular and kinetic basis form the mixed agonist/antagonist activity of estradiol
    • Melmed M, Castano E, Notides AC and Sason S: Molecular and kinetic basis form the mixed agonist/antagonist activity of estradiol. Mol Endocrinol 11: 1868-1876, 1997.
    • (1997) Mol Endocrinol , vol.11 , pp. 1868-1876
    • Melmed, M.1    Castano, E.2    Notides, A.C.3    Sason, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.