Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium

British Journal of Pharmacology

Volumn 124, Issue 6, 1998, Pages 1048-1059

  Winton, Helen L ^a   Wan, Hong ^a   Cannell, Mark B ^a   Thompson, Philip J ^b   Garrod, David R ^c   Stewart, Geoffrey A ^b   Robinson, Clive ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Allergens; Apoptosis; Asthma; Bronchial epithelium; Dermatophagoides pteronyssinus; Proteinase inhibitors; Tight junctions

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; CYSTEINE PROTEINASE; DNA FRAGMENT; LIPOCORTIN 5; MATRIX METALLOPROTEINASE INHIBITOR; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PROPIDIUM IODIDE; PROTEINASE; SERINE PROTEINASE; SOYBEAN TRYPSIN INHIBITOR;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ARTICLE; ASTHMA; CELL ADHESION; CELL CULTURE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DERMATOPHAGOIDES PTERONYSSINUS; DNA CLEAVAGE; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MONOLAYER CULTURE; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; RISK FACTOR; SENSITIZATION; STAINING;

ANIMALS; APOPTOSIS; CATALYSIS; CELL ADHESION; CELL LINE; CELL MEMBRANE PERMEABILITY; DOGS; EPITHELIAL CELLS; IMMUNOHISTOCHEMISTRY; LUNG; MITES; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS;

EID: 0031853893     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701905     Document Type: Article

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