The role of manganese superoxide dismutase in health and disease

Journal of Inherited Metabolic Disease

Volumn 21, Issue 5, 1998, Pages 598-603

  Robinson, B H ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; HYDROXYL RADICAL; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL ENZYME; PROTEIN BCL 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE;

BASAL GANGLION; BRAIN DISEASE; CARDIOMYOPATHY; CELL TYPE; CONFERENCE PAPER; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INDUCTION; HUMAN; LIPID PEROXIDATION; MITOCHONDRIAL RESPIRATION; OXIDATION REDUCTION STATE; PROTEIN INDUCTION; RESPIRATORY CHAIN;

ANIMALS; DISEASE; HEALTH; HUMANS; MICE; SUPEROXIDE DISMUTASE;

EID: 0031847248     PISSN: 01418955     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005427323835     Document Type: Conference Paper

References (26)

1. Borgstahl GEO, Parge HE, Hickey MJ, et al (1992) The structure of human manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles. Cell 71: 107-118.
2. Bourgeois J, Raha S, Tarnopolsky M, et al (1998) Alternative induction of either MnSOD or bcl-2 in response to mitochondrial disease and increased superoxide production. FEBS Lett, submitted.
3. Boveris A, Chance B (1977) Mitochondrial production of superoxide radical and hydrogen peroxide. In Reivich M, Coburn R, Lahiri S, Chance B, eds. Tissue Hypoxia and Ischemia. New York: Plenum Press, 67-82.
4. Das DK, Engelman RM, Kimura Y (1993) Molecular adaptation of cellular defences following preconditioning of heart by repeated ischemia. Cardiovasc Res 27: 578-584.
5. Das KC, Lewis-Molock Y, White CW (1995) Activation of NF-kappa-B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma cells. Am J Physiol 269: 588-602.
6. Flint DH, Tuminello JF, Emptage MH (1993) The inactivation of Fe-S cluster containing hydro-lyases by superoxide. J Biol Chem 268: 22369-22376.
7. Fridovitch I (1995) Superoxide radical and superoxide dismutases. Annu Rev Biochem 64: 97-112.
8. Gardner PR, Rainier I, Epstein LB, et al (1995) Superoxide radical and iron modulate aconitase activity in mammalian cells. J Biol Chem 270: 13399-13405.
9. Ho YS, Dey MS, Crapo JD (1996) Antioxidant enzyme expression in rat lungs during hyperoxia. Am J Physiol 270: 810-818.
10. Hockenberry DM, Oltvai ZN, Yin X-M, et al (1993) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75: 241-251.
11. Lebovitz RM, Zhang H, Vogel H, et al (1996) Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc Natl Acad Sci USA 93: 9782-9787.
12. Li Y, Huang TT, Carlson EJ, et al (1995) Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nature Genetics 11: 376-381.
13. Luo X, Pitkänen S, Robinson BH, et al (1997) Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency. J Clin Invest 99: 2877-2882.
14. Meier B, Radeke HH, Selle S, et al (1989) Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α. Biochem J 263: 539-545.
15. Nogae C, Makino H, Hata T, et al (1995) Interleukin 1α-induced expression of manganous superoxide dismutase reduces myocardial reperfusion injury in rats. J Mol Cell Cardiol 27: 2091-2099.
16. Pitkänen S, Robinson BH (1996) Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase. J Clin Invest 98: 345-351.
17. Pitkänen S, Merante F, McLeod DR, et al (1996a) Familial cardiomyopathy with cataracts and lactic acidosis: a defect in complex I (NADH-dehydrogenase) of the mitochondrial respiratory chain. Pediatr Res 39: 513-521.
18. Pitkänen S, Feigenbaum A, Laframboise R, et al (1996b) NADH-coenzyme Q reductase (complex I) deficiency: heterogeneity in phenotype and biochemical findings. J Inher Metab Dis 19: 675-686.
19. Salganik RI, Solovyova NA, Dikalov SI, et al (1994) Inherited enhancement of hydroxyl radical generation and lipid peroxidation in the S strain rats results in DNA rearrangements, degenerative diseases, and premature aging. Biochem Biophys Res Commun 199: 726-733.
20. Shimoda-Matsubayashi S, Matsumine H, Kobayashi T, et al (1996) Structural dimorphism in the mitochondrial targetting sequence in the human manganese superoxide dismutase gene. Biochem Biophys Res Commun 226: 561-565.
21. Wan XS, Devalaraja MN, St Clair DK (1994) Molecular structure and organization of the human manganese superoxide dismutase gene. DNA Cell Biol 13: 1127-1136.
22. Warner BB, Stuart L, Gebb S, et al (1996) Redox regulation of manganese superoxide dismutase. Am J Physiol 271: 150-158.
23. Weidau-Pazos M, Trudell JR, Altenbach C, et al (1996) Expression of bcl-2 inhibits cellular radical generation. Free Radical Res 24: 205-212.
24. Wolvetang EJ, Johnson KL, Krauer K, et al (1994) Mitochondrial respiratory chain inhibitors induce apoptosis. FEBS Lett 339: 40-44.
25. Wong GHW, Elwell JH, Oberly LW, et al (1989) Mangenous superoxide dismutase is essential for cellular resistance to cytotoxicity of TNF. Cell 58: 923-931.
26. Zhu W, Cowie AC, Wasfy GW, et al (1996) Bcl-2 mutants with restricted cellular location reveal spatially distinct pathways for apoptosis in different cell types. EMBO J 15: 4130-4141.