Detection of DCC and Ki-ras gene alterations in colorectal carcinoma tissue as prognostic markers for liver metastatic recurrence

Cancer

Volumn 77, Issue 8 SUPPL., 1996, Pages 1729-1735

  Kato, Masataka ^a   Ito, Yasushi ^a   Kobayashi, Susumu ^a   Isono, Kaichi ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

colorectal carcinoma; DCC; Ki ras; liver metastasis; loss of heterozygosity

Indexed keywords

DNA; PROTEIN P53; TUMOR MARKER;

ADULT; AGED; ALLELE; CANCER MORTALITY; CANCER RECURRENCE; CODON; COLORECTAL CARCINOMA; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENE MUTATION; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; INCIDENCE; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS;

ADENOCARCINOMA; AGED; BASE SEQUENCE; CODON; COLORECTAL NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; GENE DELETION; GENES, DCC; GENES, P53; GENES, RAS; HETEROZYGOTE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 0030001892     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19960415)77:8<1729::AID-CNCR47>3.0.CO;2-Z     Document Type: Conference Paper

References (26)

1. Welch JP, Donaldson GA. Detection and treatment of recurrent cancer of the colon and rectum. Am J Surg 1978;135:505-11.
2. August DA, Sugarbaker PH, Ottow RT, Ginola RJ, Schneider PD. Hepatic resection of colorectal metastases. Influence of clinical factors and adjuvant intraperitoneal 5-FU via Tenckhoff catheter. Ann Surg 1985;201:210-8.
3. Cady B, McDermott WV. Major hepatic resection for metachronous metastases from colon cancer. Ann Surg 1985;201:204-9.
4. Deans GT, Parks TG, Rowlands BJ, Spence RAJ. Prognostic factors in colorectal cancers. Br J Surg 1992;79:608-13.
5. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preinsinger AC, Leppert M, et al. Genetic alteration during colorectal-tumor development. N Engl J Med 1988;319:525-32.
6. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-67.
7. Hamilton SR. The molecular genetics of colorectal neoplasia. Gastroenterology 1993;105:3-7.
8. Iino H, Fukayama M, Maeda Y, Koike M, Mori T, Takahashi T. Molecular genetics for clinical management of colorectal carcinoma. Cancer 1994;73:1324-31.
9. Jen J, Kim H, Piantadosi S, Liu ZF, Levitt RC, Sistonen P, et al. Allelic loss of chromosome 18q and prognosis in colorectal cancer. N Engl J Med 1994;331:213-21.
10. Ookawa K, Sakamoto M, Hirohashi S, Yoshida Y, Sugimura T. Terada M, et al. Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma. Int J Cancer 1993;53:382-7.
11. Maniatis T, Fritsch EF, Sambrook J. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor: Cold Spring Harbor, 1989.
12. Feinberg AP, Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983;132:6-13.
13. Cunningham J, Lust JA, Schaid DJ, Bren GD. Carpenter HA, Rizza E, et al. Expression of p53 and 17p allelic loss in colorectal carcinoma. Cancer Res 1992;52:1974-80.
14. Uchino S, Tsuda H, Noguchi M, Yokota J, Terada M, Saito T, et al. Frequent loss of heterozygosity at the DCC locus in gastric cancer. Cancer Res 1992;52:3099-102.
15. Levi S, Ispizua AU, Gill R, Thomas DM, Gilbertson J, Foster C, et al. Multiple K-ras codon 12 mutations in cholangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique. Cancer Res 1991;51:3497-502.
16. Yanoshita RK, Konishi M, Fukunari H, Tanaka K, Miyaki M. Loss of expression of the DCC gene during progression of colorectal carcinomas in familial adenomatous polyposis and non-familial adenomatous polyposis patients. Cancer Res 1992;52:3801-03.
17. Itoh F, Hinoda Y, Ohe M, Ohe Y, Ban T, Endo T, et al. Decreased expression of DCC mRNA in human colorectal cancers. Int J Cancer 1993;53:260-3.
18. Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 1990;247:49-56.
19. Rodrigues NR, Rowan A, Smith MEF, Kerr IB, Bodmer WF, Gannon JV, et al. p53 mutations in colorectal cancer. Proc Natl Acad Sci USA 1990;87:7555-9.
20. Scott N, Sagar P, Stewart J, Blair GE, Dixon MF, Quirke P. p53 in colorectal cancer: clinicopathological correlation and prognostic significance. Br J Cancer 1991;63:317-9.
21. Bos JL, Fearon ER, Hamilton SR, Vries MV, Boom V, Vogelstein B. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987;327:293-7.
22. Forrester K, Almoguera C, Han K, Grizzle HK, Perucho M. Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature 1987;327:298-303.
23. Fujimori T, Satonaka K, Idei YY, Nagasako K, Maeda S. Non-involvement of ras mutations in flat colorectal adenomas and carcinomas. Int J Cancer 1994;57:51-5.
24. Yamagata S, Muto T, Uchida Y, Masaki T, Sawada T, Tsuno N, et al. Lower incidence of K-ras codon 12 mutations in flat colorectal adenomas than in polypoid adenomas. Jpn J Cancer Res 1994;85:147-51.
25. Mitooka H, Fujimori T, Ohno S, Morimoto S, Nakashima T, Ohmoto A, et al. Chromoscopy of the colon using indigo carmine dye with electrolyte lavage solution. Gastrointes Endosc 1992;38:373-4.
26. Ikegami M. A pathological study on colorectal cancer. From de novo carcinoma to advanced carcinoma. Acta Pathol Jpn 1987;37:21-37.