Transforming growth factor-β2 regulates C3 secretion in monocytes through a protein kinase C-dependent pathway

Molecular Immunology

Volumn 35, Issue 1, 1998, Pages 1-11

  Drouin, S M ^a   Kiley, S C ^b   Carlino, J A ^c,e   Barnum, Scott R ^a,d  

^a University of Alabama at Birmingham   (United States)

^b Adirondack Biomedical Research Institute Inc   (United States)

^c Celtrix Pharmaceuticals   (United States)

^d University of Alabama at Birmingham   (United States)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Complement monocytes; Protein kinase C; Transforming growth factor

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; CALPHOSTIN C; COMPLEMENT COMPONENT C3; PROTEIN KINASE C; TRANSFORMING GROWTH FACTOR BETA2;

ARTICLE; COMPLEMENT ACTIVATION; MONOCYTE; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

EID: 0031838209     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(98)00014-5     Document Type: Article

References (55)

1. Bakouche, O., Moreau, J.L., Lachman, L.B., 1992. Secretion of IL-I: role of protein kinase C. J. Immun. 148, 84-91.
2. Barnum, S.R., Fey, G., Tack, B.F., 1990. The biosynthesis and genetics of C3. Curr. Top. Microbiol. Immun. 153, 23-43.
3. Barnum, S.R., Ishii, Y., Agrawal, A., Volanakis, J.E., 1992. Production and interferon-α-mediated regulation of complement component C2 and factors B and D by the astroglioma cell line U105-MG. Biochem. J. 287, 595-601.
4. Barnum, S.R., Jones, J.L., 1994. Transforming growth factor-β1 inhibits inflammatory cytokine-induced C3 gene expression in astrocytes. J. Immun. 152, 756-773.
5. Baumgartner, R.A., Deramo, V.A., Beaven, M.A., 1996. Constitutive and inducible mechanisms for synthesis and release of cytokines in immune cell lines. J. Immun. 157, 4087-4093.
6. Bednarczyk, J.L., Capra, J.D., 1988. Post-translational processing of the murine third component of complement. Scand. J. Immun. 27, 83-95.
7. Bradford, M.M., 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt. Biochem. 72, 248-254.
8. Brandes, M.F., Wakefield, L.M., Wahl, S.M., 1991. Modulation of monocyte type I TGF-β receptors by inflammatory stimuli. J. Biol. Chem. 266, 19697-19703.
9. Bruns, R.F., Miller, F.D., Merriman, R.L., Howbert, J.J., Heath, W.F., Kobayashi, E., Takahashi, I., Tamaoki, T., Nakano, H., 1991. Inhibition of protein kinase C is light-dependent. Biochem. Biophys. Res. Commun. 176, 288-293.
10. Buccione, R., Bannykh, S., Santone, I., Baldassarre, M., Facchiano, F., Bozzi, Y., Di Tullio, G., Mironov, A., Luini, A., De Matteis, M.A., 1996. Regulation of constitutive exocytic transport by membrane receptors. J. Biol. Chem. 271, 3523-3533.
11. Castagna, M., Takai, Y., Kaibuchi, K., Sano, K., Kikkawa, U., Nishizuka, Y., 1982. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J. Biol. Chem. 257, 7847-7851.
12. Chen, R., Miettinen, P.J., Maruoka, E.M., Choy, L., Derynck, R., 1995. A WD-domain protein that is associated with and phosphorylated by the type II TGF-β receptor. Nature 377, 548-552.
13. Disatnik, M., Jones, S.N., Mochly-Rosen, D., 1995. Stimulus-dependent, subcellular localization of activated protein kinase C; a study with acidic fibroblast growth factor and transforming growth factor-β1 in cardiac myocytes. J. Molec. Cell. Cardiol. 27, 2473-2481.
14. Drouin, S.M., Fenster, S.D., Carlino, J.A., Barnum, S.R., 1995. Transforming growth factor-β2-mediated regulation of C3 gene expression in monocytes and hepatocytes. FASEB J. 9, 517A.
15. Drouin, S.M., Carlino, J.A., Barnum, S.R., 1996. Transforming growth factor-β2-mediated regulation of C3 gene expression in monocytes. Molec. Immun. 33, 1025-1034.
16. Fabbri, M., Bannykh, S., Balch, W.E., 1994. Export of protein from the endoplasmic reticulum is regulated by a diacylglycerol/phorbol ester binding protein. J. Biol. Chem. 269, 26848-26857.
17. Faded, H.F., Tachibana, T., Okuda, T.. 1993. The secretion of the third component of complement (C3) by human polymorphonuclear leukocytes from both normal and systemic lupus erythematosus cases. Scand. J. Immun. 37, 19-28.
18. Frey, R.S., Mulder, K.M., 1997. Involvement of extracellular signal-regulated kinase 2 and stress-activated protein kinase/Jun N-terminal kinase activation by transforming growth factor-β in the negative growth control of breast cancer cells. Cancer Res. 57, 628-633.
19. Goodnight, J., Mischak, H., Kolch, W., Mushinski, J.F., 1995. Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. J. Biol. Chem. 270, 9991-10001.
20. Halstead, J., Kemp, K., Ignotz, R.A., 1995. Evidence for involvement of phosphatidylcholine-phospholipase C and protein kinase C in transforming growth factor-β signaling. J. Biol. Chem. 270, 13600-13603.
21. Hidaka, H., Inagaki, M., Kawamoto, S., Sasaki, Y., 1984. Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 23, 5036-5041.
22. Hogansen, A.K.M., Hestdal, K., Hogansen, K., Abrahamsen, T.G., 1995. Transforming growth factor-β modulates C3 and factor B biosynthesis and complement receptor 3 expression in cultured human monocytes. J. Leukoc. Biol. 57, 287-296.
23. Hug, H., Sarre, T.F., 1993. Protein kinase C isoenzymes: divergence in signal transduction? Biochem. J. 291, 329-343.
24. Kiley, S.C., Olivier, A.R., Gordge, P.C., Ryves, W.J., Evans, F.J., Ways, D.K., Parker, P.J., 1994. 12-Deoxyphorbol-13-O-phenylacetate-20-acetate is not protein kinase C-β isozyme-selective in vivo. Carcinogenesis 15, 319-324.
25. Kiley, S.C., Parker, P.J., 1995. Differential localization of protein kinase C isozymes in U937 cells: evidence for distinct isozyme functions during monocyte differentiation. J. Cell Sci. 108, 1003-1016.
26. Kiley, S.C., Parker, P.J., 1997. Defective microtubule reorganization in phorbol ester-resistant U937 variants: reconstitution of the normal cell phenotype with nocodazole treatment. Cell Growth Diff. 8, 231-242.
27. Kobayashi, E., Nakano, H., Morimoto, M., Tamaoki, T., 1989. Calphostin C (UCN-1028C), a novel microbial compound. is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159, 548-553.
28. Lastres, P., Almendro N., Bellón, T., López-Guerrero, J.A., Eritja, R., Bernabéu, C., 1994. Functional regulation of platelet/endothelial cell adhesion molecule-1 by TGF-β1 in promonocytic U937 cells. J. Immun. 153, 4206-4218.
29. Leach, K.L., Powers, E.A., McGuire, J.C., Dong, L., Kiley, S.C., Jaken, S., 1988. Monoclonal antibodies specific for type 3 protein kinase C recognize distinct domains of protein kinase C and inhibit in vitro functional activity. J. Biol. Chem. 263, 13223-13230.
30. Lehel, C., Olah, Z., Jakab, G., Anderson, W.B., 1995. Protein kinase C ε is located to the Golgi via its zinc-finger domain and modulates Golgi function. Proc. Natn. Acad. Sci. U.S.A. 92, 1406-1410.
31. Marais, R.M., Parker, P.J., 1989. Purification and characterization of bovine protein kinase C isotypes α, β and γ. Eur. J. Biochem. 182, 129-137.
32. Massagúé, J., Attisano, L., Wrana, J.L., 1994. The TGF-β family and its composite receptors. Trends Cell Biol. 4, 172-178.
33. McCartney-Francis, N.L., Wahl, 1994. Transforming growth factor-β: a matter of life and death. J. Leukoc. Biol. 55, 401-409.
34. Minta. J.O., Isenman, D.E., 1987. Biosynthesis of the third component of complement by the human monocyte-like cell line, U937. Molec. Immun. 24, 1105-1111.
35. Müller-Eberhard, H.J., 1988. Molecular organization and function of the complement system. Annu. Rev. Biochem. 57, 321-347.
36. Naughton, M.A., Botto, M., Carter, M.J., Alexander, G.J., Goldman, J.M., Walport, M.J., 1996. Extrahepatic secreted complement C3 contributes to circulating C3 levels in humans. J. Immun. 156, 3051-3056.
37. Oda, K., Hirose, S., Takami, N., Maisumi, Y., Takatsuki, A., Ikehara. Y., 1987. Brefeldin A arrests the intracellular transport of a precursor of complement C3 before its conversion site in rat hepatocytes. FEBS Lett. 214, 135-138.
38. Ohtsuki, M., Massagúé, J., 1992. Evidence for the involvement of protein kinase activity in transforming growth factor-β signal transduction. Molec. Cell. Biol. 12, 261-265.
39. Okuda, T., Tachibana, T., 1992. Secretion and function of the third component of complement (C3) by murine leukocytes. Int. Immun. 4, 681-690.
40. Prestle, J., Pfizenmaier, K., Brenner, J., Johannes, F.J., 1996. Protein kinase C μ is located at the Golgi compartment. J. Cell Biol. 134, 1401-1410.
41. Reimann, T., Hempel, U., Krautwald, S., Axmann, A., Scheibe, R., Seidel, D., Wenzel, K.W., 1997. Transforming growth factor-β1 induces activation of Ras, Raf-1, MEK and MAPK in rat hepatic stellate cells. FEBS Lett. 403, 57-60.
42. Roberts, A.B., Sporn, M.B., 1990. The transforming growth factor βs. In Sporn, M.B., Roberts, A.B. (Eds) Peptide Growth Factors and their Receptors. Springer-Verlag, Heidelberg, p. 419.
43. Schaap, D., Parker, P.J., Bristol, A., Kriz, R., Knopf, J., 1989. Unique substrate specificity and regulatory properties of PKC-ε: a rationale for diversity. FEBS Lett. 243, 351-357.
44. Shibuya, H., Yamaguchi, K., Shirakabe, K., Tonegawa, A., Gotoh, Y., Ueno, N., Irie, K., Nishida, E., Matsumoto. K., 1996. TAB1: An activator of the TAK1 MAPKKK in TGF-β signal transduction. Science 272, 1179-1182.
45. Simon, J.P., Ivanov, I.E., Shopsin, B., Hersh, D., Adesnik, M., Sabatini, D.D., 1996. The in vitro generation of post-Golgi vesicles carrying viral envelope glycoproteins requires an ARF-like GTP-binding protein and a protein kinase C associated with the Golgi apparatus. J. Biol. Chem. 271, 16952-16961.
46. Sundstrom, C., Nilsson, K., 1976. Establishment and characterization of a human histiocytic lymphoma cell line (U937). Int. J. Cancer 17, 565-577.
47. Taipale, J., Matikainen, S., Hurme, M., Keski-Oja, J., 1994. Induction of transforming growth factor-[gkb1]1 and its receptor expression during myeloid leukemia cell differentiation. Cell Growth Diff. 5, 1309-1319.
48. Volanakis, J.E., Fearon, D.T., 1992. The molecular biology of the complement system. In McCarty, D.J., Koopman, W.J. (Eds), Arthritis and Allied Conditions-A Textbook of Rheumatology 12th Ed. Lea & Febiger, Philadelphia, pp. 445-467.
49. RAS farnesyltransferase α. subunit in TGF-β and activin signaling. Science 271, 1120-1122.
50. Ways, D.K., Cook, P.P., Webster, C., Parker, P.J., 1992. Effect of phorbol esters on protein kinase C-ζ. J. Biol. Chem. 267, 4799-4805.
51. Ways, D.K., Messer, B.R., Garris, T.O., Qin, W., Cook, P.P., Parker, P.J., 1992. Modulation of protein kinase C-ε by phorbol esters in the monoblastoid U937. Cancer Res. 52, 5604-5609.
52. Ways, K., Riddle, R., Ways, M., Cook, P., 1991. Effect of phorbol esters on cytosolic protein kinase C content and activity in the human monoblastoid U937 cell. J. Biol. Chem. 266, 1258-1264.
53. Westermann, P., Knoblich, M., Maier, O., Lindschau, C., Haller, H., 1996. Protein kinase C bound to the Golgi apparatus supports the formation of constitutive transport vesicles. Biochem. J. 320, 651-658.
54. Wrana, J.L., Attisano, L., Wieser, R., Ventura, F., Massagúé, J., 1994. Mechanism of activation of the TGF-β receptor. Nature 370, 341-347.
55. Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., Matsumoto, K., 1995. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270, 2008-2011.