Comparison of electrostatic similarity approaches applied to a series of ketanserin analogues with 5-HT(2A) antagonistic activity

Quantitative Structure-Activity Relationships

Volumn 17, Issue 3, 1998, Pages 199-204

  Lozoya, Estrella ^d   Berges, Maribel ^d   Rodríguez, Jesús ^c   Sanz, Ferran ^d   Loza, Maria Isabel ^a,b   Moldes, Victor M ^d   Masaguer, Cristian F ^b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b Universidade de Santiago de Compostela   (Spain)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d NONE

Author keywords

5 HT(2A) receptor; Cluster analysis; Electrostatic similarity; Ketanserin analogues; MEPCOMP; MEPSIM; Molecular electrostatic potential; Molecular similarity

Indexed keywords

BINDING ENERGY; BIOACTIVITY; CLUSTER ANALYSIS;

5-HT(2A) RECEPTOR; ANTAGONISTIC ACTIVITY; BINDING AFFINITIES; ELECTROSTATIC SIMILARITY; KETANSERIN ANALOG; MEPCOMP; MEPSIM; MOLECULAR ELECTROSTATIC POTENTIAL DISTRIBUTIONS; MOLECULAR ELECTROSTATIC POTENTIALS; MOLECULAR SIMILARITY;

ELECTROSTATICS;

KETANSERIN; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR;

ARTICLE; ELECTRIC POTENTIAL; PRIORITY JOURNAL; RECEPTOR AFFINITY;

EID: 0031835351     PISSN: 09318771     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-3838(199806)17:03<199::aid-qsar199>3.3.co;2-r     Document Type: Article

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