Synthesis, affinity at 5-HT(2A), 5-HT(2B) and 5-HT(2C) serotonin receptors and structure-activity relationships of a series of cyproheptadine analogues

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 5, 1997, Pages 842-848

  Honrubia, Maria Angeles ^a   Jesús, Rodriguez ^a   Dominguez, Rosa ^a   Lozoya, Estrella ^b   Manaut, Francesc ^b   Seijas, Julio A ^a   Villaverde, Maria Carmen ^a   Calleja, Jose M ^a   Cadavid, Maria Isabel ^a   Maayani, Saul ^c   Sanz, Ferran ^b   Loza, Maria Isabel ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

5 HT2 receptor; Cyproheptadine; Molecular feature

Indexed keywords

1 METHYL 4 (9H THIOXANTHEN 9 YLIDENE)PIPERIDINE; 1 METHYL 4 (9H XANTHEN 9 YLIDENE)PIPERIDINE; 4 (9H FLUOREN 9 YLIDENE) 1 METHYLPIPERIDINE; 4 BENZHYDRYLIDENE 1 METHYLPIPERIDINE; 4 METHYLPHENYLMETHYLENE 1 METHYLPIPERIDINE; CYPROHEPTADINE; DRUG ANALOG; KETANSERIN; MESULERGINE; SEROTONIN; SEROTONIN 2 RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN CORTEX; CHEMICAL STRUCTURE; CHOROID PLEXUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SYNTHESIS; MALE; MOLECULAR MODEL; MUSCLE CONTRACTION; NONHUMAN; RAT; RECEPTOR AFFINITY; STOMACH FUNDUS; STRUCTURE ACTIVITY RELATION; SWINE;

EID: 0342981540     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.842     Document Type: Article

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