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Efficacy and safety profile of gemcitabine in non-small cell lung cancer. Phase II study
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2
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0028020890
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Phase II study of gemcitabine (2′,2′-difluorodeoxycytidine) in previously treated ovarian cancer patients
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B. Lund, O.P. Hansen, K. Theilade, M. Hansen, J.P. Neijt, Phase II study of gemcitabine (2′,2′-difluorodeoxycytidine) in previously treated ovarian cancer patients, J. Natl. Cancer Inst., 86: 1530-1533 (1994).
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84920312988
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Combination chemotherapy studies with gemcitabine
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in press
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C.J.A. van Moorsel, G. Veerman, A.M. Bergman, A. Guechev, J.B. Vermorken, P.E. Postumus, G.J. Peters, Combination chemotherapy studies with gemcitabine, Sem. Oncol., in press.
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Sem. Oncol.
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Van Moorsel, C.J.A.1
Veerman, G.2
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Peters, G.J.7
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4
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0027180521
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2′,2′-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA from tumour cell lines
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V.W.T. Ruiz van Haperen, G. Veerman, J.B. Vermorken, G.J. Peters, 2′,2′-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA from tumour cell lines, Biochem. Pharmacol., 46: 762-766 (1993).
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5
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0026324313
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Action of 2′,2′-difluorodeoxycytidine on DNA synthesis
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P. Huang, S. Chubb, L.W. Hertel, G.B. Grindey, W. Plunkett, Action of 2′,2′-difluorodeoxycytidine on DNA synthesis, Cancer Res., 51: 6110-6117 (1991).
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6
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Comparison off the substrate specifities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs
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S. Eriksson, B. Kierszuk, B. Munch-Petersen, B. Oberg, N.G. Johansson, Comparison off the substrate specifities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs, Biochem. Biophys. Res. Comm., 176: 586-592 (1991).
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7
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0025049372
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Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine
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V. Heinemann, Y-Z Xu, S. Chubb, A. Sen, L.W. Hertel, G.B. Grindey, W. Plukett, Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine, Mol. Pharmacol., 38: 567-572 (1990).
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Plukett, W.7
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8
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0028214771
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New targets for pyrimidine antimetabolites for the treatment of solid tumours. II: Deoxycytidine kinase
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V.W.T. Ruiz van Haperen, G.J. Peters, New targets for pyrimidine antimetabolites for the treatment of solid tumours. II: Deoxycytidine kinase, Pharmacy World Sci., 16: 104-112 (1994).
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Pharmacy World Sci.
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Ruiz Van Haperen, V.W.T.1
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0024329881
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The biochemistry of P-glycoprotein-mediated multidrug resistance
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J.A. Endicott and V. Ling, The biochemistry of P-glycoprotein-mediated multidrug resistance, Annu. Rev. Biochem., 58: 137-171 (1989).
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Endicott, J.A.1
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10
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0028054888
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Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs
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C.E. Grant, G. Valdimarsson, D.R. Hipfner, K.C. Almquist, S.P.C. Cole, R.G. Deeley, Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs, Cancer Res., 54: 357-361 (1994).
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Cancer Res.
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Grant, C.E.1
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Deeley, R.G.6
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11
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84920308431
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Cross-resistancce to anti-folates in multi drug resisttant cell lines with P-glycoprotein or multi drug resistance related protein expression
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in press
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B. Van Triest, H.M. Pinedo, F. Telleman, C.L. Van der Wilt, G. Jansen, G.J. Peters, Cross-resistancce to anti-folates in multi drug resisttant cell lines with P-glycoprotein or multi drug resistance related protein expression, Biochem. Pharm., in press.
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Biochem. Pharm.
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Van Triest, B.1
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Van Der Wilt, C.L.4
Jansen, G.5
Peters, G.J.6
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12
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0025878872
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Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing
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Y.P. Keepers, P.E. Pizao, G.J. Peters, J. van Ark-Otte, B. Winograd, H.M. Pinedo, Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing, Eur. J. Cancer, 27: 897-900 (1991).
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Keepers, Y.P.1
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Winograd, B.5
Pinedo, H.M.6
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13
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0027451344
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Deoxycytidine kinase and deoxycytidine deaminase activities in human xenografts
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V.W.T. Ruiz van Haperen, G. Veerman, B.J.M. Braakhuis, J.B. Vermorken, E. Boven, A. Leyva, G.J. Peters, Deoxycytidine kinase and deoxycytidine deaminase activities in human xenografts, Eur. J. Cancer, 29A: 2132-2137 (1993).
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Eur. J. Cancer
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Van Ruiz Haperen, V.W.T.1
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Vermorken, J.B.4
Boven, E.5
Leyva, A.6
Peters, G.J.7
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14
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0028105119
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Schedule dependence of sensitivity to 2′,2′-difluorodeoxycytidine (gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumour cell lines and solid tumours
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V.W.T. Ruiz van Haperen, G. Veerman, E. Boven, P. Noordhuis, J.B. Vermorken, G.J. Peters, Schedule dependence of sensitivity to 2′,2′-difluorodeoxycytidine (gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumour cell lines and solid tumours, Biochem. Pharmacol, 48: 1327-1339 (1994).
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Van Ruiz Haperen, V.W.T.1
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Vermorken, J.B.5
Peters, G.J.6
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15
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0031021259
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The antiproliferative effect of 8-chloro-adenosine, an metabolite of 8-chloro-cyclic adenosine monophosphate, and disturbances in nucleic acid synthesis and cell cycle kinetics
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C.H. Langeveld, C.A.M. Jongenelen, J.W.M. Theeuwes, J.P.A. Baak, J.J. Heimans, J.C. Stoof, G.J. Peters, The antiproliferative effect of 8-chloro-adenosine, an metabolite of 8-chloro-cyclic adenosine monophosphate, and disturbances in nucleic acid synthesis and cell cycle kinetics, Biochem. Pharm., 53:1441-148 (1997).
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Heimans, J.J.5
Stoof, J.C.6
Peters, G.J.7
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16
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0029875635
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Synergistic interaction between cisplatin and gemcitabine in vitro
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A.M. Bergman, V.W.T Ruiz van Haperen, G. Veerman, C.M. Kuiper, G.J. Peters, Synergistic interaction between cisplatin and gemcitabine in vitro, Clin. Cancer Res., 2: 521-530 (1996).
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Clin. Cancer Res.
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17
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0031039517
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In vitro cross-resistance and collateral sensitivity in seven resistant small-cell lung cancer cell lines: Preclinical identification of suitable drug partners to taxotere, taxol, topotecan and gemcitabine
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P.B. Jensen, B. Holm, M. Sorensen, I.J. Christensen, M. Sehested, In vitro cross-resistance and collateral sensitivity in seven resistant small-cell lung cancer cell lines: preclinical identification of suitable drug partners to taxotere, taxol, topotecan and gemcitabine, Brit. J. Cancer, 75: 869-877 (1997).
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