Higher-order chromatin structure-dependent repair of DNA double-strand breaks: Factors affecting elution of DNA from nucleoids

Radiation Research

Volumn 149, Issue 6, 1998, Pages 533-542

  Johnston, P J ^a   MacPhail, S H ^a   Banath J P ^a   Olive, P L ^a  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CYCLE S PHASE; CELL KILLING; CELL NUCLEUS MATRIX; CELL SURVIVAL; CHROMATIN STRUCTURE; CHROMOSOME ABERRATION; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; GENETIC RECOMBINATION; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; CHO CELLS; CHROMATIN; CRICETINAE; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; HUMANS;

EID: 0031833112     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579899     Document Type: Article

References (50)

1. D. Blöcher and W. Pohlit, DNA double strand breaks in Ehrlich ascites tumour cells at low doses of X-rays. II. Can cell death be attributed to double strand breaks? Int. J. Radiat. Biol. 42, 329-338 (1982).
2. P. E. Bryant, Enzymatic restriction of mammalian cell DNA: Evidence for double strand breaks as potentially lethal lesions. Int. J. Radiat. Biol. 48, 55-60 (1985).
3. P. E. Bryant, D. A. Birch and P. A. Jeggo, High chromosomal sensitivity of Chinese hamster xrs 5 cells to restriction endonuclease induced DNA double-strand breaks. Int. J. Radiat. Biol. 52, 537-554 (1987).
4. D. Frankenberg, M. Frankenberg-Schwager and R. Harbich, Interpretation of the shape of survival curves in terms of induction and repair/misrepair of DNA double strand breaks. Br. J. Cancer 49, 233-238 (1984).
5. 2 stages of the cell cycle. Mutat. Res. 69, 293-305 (1980).
6. P. L. Olive, J. P. Banáth and H. S. MacPhail, Lack of a correlation between radiosensitivity and DNA double-strand break induction or rejoining in six human tumor cell lines. Cancer Res. 54, 3939-3946 (1994).
7. P. A. Jeggo, Studies on mammalian mutants defective in rejoining double-strand breaks in DNA. Mutat. Res. 239, 1-6 (1990).
8. J. Dahm-Daphi, E. Dikomey, C. Pyttlik and P. A. Jeggo, Reparable and nonreparable DNA strand breaks induced by X-irradiation in CHO K1 cells and the radiosensitive mutants xrs1 and xrs5. Int. J. Radiat. Biol. 64, 19-26 (1993).
9. G. Iliakis, R. Mehta and M. Jackson, Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose dependent: Implications for the mechanism of radiosensitivity. Int. J. Radiat. Biol. 61, 315-321 (1992).
10. L. M. Kemp, S. G. Sedgwick and P. A. Jeggo, X-ray sensitive mutants of Chinese hamster ovary cells deficient in double-strand break rejoining. Mutat. Res. 132, 189-196 (1984).
11. D. T. Goodhead, Initial events in the cellular effects of ionising radiations: Clustered damage in DNA. Int. J. Radiat. Biol. 65, 7-17 (1994).
12. C. von Sonntag, The Chemical Basis of Radiation Biology. Taylor & Francis, London, 1987.
13. J. F. Ward, Biochemistry of DNA lesions. Radiat. Res. 105 (Suppl.), S103-S111 (1985).
14. W. R. Holley and A. Chatterjee, Clusters of DNA induced by ionizing radiation: Formation of short DNA fragments. I. Theoretical modeling. Radiat. Res. 145, 188-199 (1996).
15. M. Löbrich, P. K. Cooper and B. Rydberg, Non-random distribution of DNA double-strand breaks induced by particle radiation. Int. J. Radiat. Biol. 70, 493-503 (1996).
16. B. Rydberg, Clusters of DNA damage induced by ionizing radiation: Formation of short DNA fragments. II. Experimental detection. Radiat. Res. 145, 200-209 (1996).
17. P. J. Johnston and P. E. Bryant, A component of DNA double-strand break repair is dependent on the spatial orientation of the lesions within the higher-order structures of chromatin. Int. J. Radiat. Biol. 66, 531-536 (1994).
18. P. R. Cook and I. A. Brazell, Supercoils in human DNA. J. Cell Sci. 19, 261-279 (1975).
19. M. O. Bradley and K. W. Kohn, X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Res. 7, 793-804 (1979).
20. P. J. Johnston, P. L. Olive and P. E. Bryant, Higher-order chromatin structure-dependent repair of DNA double-strand breaks: Modeling the elution of DNA from nucleoids. Radiat. Res. 148, 561-567 (1997).
21. P. L. Olive and P. J. Johnston, DNA damage from oxidants: Influence of lesion complexity and chromatin organisation. Oncol. Res. 9, 287-294 (1997).
22. P. J. Johnston, S. H. MacPhail, T. D. Stamato, C. U. Kirchgessner and P. L. Olive, Higher-order chromatin structure-dependent repair of DNA double-strand breaks: Involvement of the V(D)J recombination DSB repair pathway. Radiat. Res. 149, 455-462 (1998).
23. G. Iliakis, R. Okayasu and R. Seaner, Radiosensitive xrs-5 and parental CHO cells show identical DNA neutral filter elution dose-response: implications for relationship between cell radiosensitivity and induction of DNA double strand breaks. Int. J. Radiat. Biol. 54, 55-62 (1988).
24. P. L. Olive, DNA organisation affects cellular radiosensitivity and detection of initial DNA strand breaks. Int. J. Radiat. Biol. 62, 389-396 (1992).
25. 125I decay. Int. J. Radiat. Biol. 59, 343-357 (1991).
26. G. E. Iliakis, L. Metzger, N. Denko and T. D. Stamato, Detection of DNA double-strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis. Int. J. Radiat. Biol. 59, 321-341 (1991).
27. 125IdUrd. Int. J. Radiat. Biol. 64, 349-358 (1993).
28. D. Wlodek and P. L. Olive, Neutral filter elution detects differences in chromatin organisation which can influence cellular radiosensitivity. Radiat. Res. 132, 242-247 (1992).
29. T. C. Pretlow and T. P. Pretlow, Centrifugal elutriation (counter-streaming centrifugation) of cells. Cell Biophys. 1, 195-210 (1979).
30. D. A. Jackson, J. Yuan and P. R. Cook, A gentle method for preparing cyto- and nucleo-skeletons and associated chromatin. J. Cell Sci. 90, 365-378 (1988).
31. M. M. Elkind and G. F. Whitmore, The Radiobiology of Cultured Mammalian Cells. Gordon and Breach, New York, 1967.
32. O. Östling and K. J. Johanson, Microelectrophoretic study of radiation induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 123, 291-298 (1984).
33. T. A. Hughes, A. Pombo, J. McManus, P. Hozak, D. A. Jackson and P. R. Cook, On the structure of replication and transcription factories. J. Cell Sci. Suppl. 19, 59-65 (1995).
34. J. Mirkovitch, S. M. Gasser and U. K. Laemmli, Relation of chromosome structure and gene expression. Phil. Trans. R. Soc. Lond. B 317, 563-574 (1987).
35. J. Mirkovitch, S. M. Gasser and U. K. Laemmli, Scaffold attachment of DNA loops in metaphase chromosomes. J. Mol. Biol. 200, 101-109 (1988).
36. J. R. Paulson, Scaffold morphology in histone-depleted HeLa metaphase chromosomes. Chromosoma 97, 289-295 (1989).
37. J. R. Paulson and U. K. Laemmli, The structure of histone depleted metaphase chromosomes. Cell 12, 817-827 (1977).
38. M. H. Fox, D. J. Amdt-Jovin, T. M. Jovin, P. H. Baumann and M. Robert-Nicoud, Spatial and temporal distribution of DNA replication sites localised by immunofluorescence and confocal microscopy in mouse fibroblasts. J. Cell Sci. 99, 247-253 (1991).
39. P. Hozak, A. B. Hassan, D. A. Jackson and P. R. Cook, Visualisation of replication factories attached to a nucleoskeleton. Cell 73, 361-373 (1993).
40. J. P. Vaughn, J. P. Dijkwel, L. H. F. Mullenders and J. L. Hamlin, Replication forks are associated with the nuclear matrix. Nucleic Acids Res. 18, 1965-1969 (1990).
41. S. J. McCready, J. Godwin, D. W. Mason, I. A. Brazell and P. R. Cook, DNA is replicated at the nuclear cage. J. Cell Sci. 46, 365-386 (1980).
42. B. J. Brewer and W. L. Fangman, The localization of replication origins on ARS plasmids in S. cerevisiae. Cell 51, 463-471 (1987).
43. W. C. Dewey and N. Albright, Developing a model of DNA replication to be used for Monte Carlo calculations that predict the sizes and shapes of molecules resulting from DNA double-strand breaks induced by X irradiation during DNA synthesis. Radiat. Res. 148, 421-434 (1997).
44. W. C. Dewey, R. S. L. Wong and N. Albright, Pulsed-field electrophoretic migration of DNA broken by X irradiation during DNA synthesis: Experimental results compared with Monte Carlo calculations. Radiat. Res. 148, 413-420 (1997).
45. P. R. Cook, The nucleoskeleton and the topology of transcription. Eur. J. Biochem. 185, 487-501 (1989).
46. P. R. Cook, The nucleoskeleton and the topology of replication. Cell 66, 627-635 (1991).
47. M. Ronne, A. O. Gyldenholm and C. O. Storm. Minihands and chromosome structure. A theory. Anticancer Res. 15, 249-254 (1995).
48. J. J. Yunis, Mid-prophase human chromosomes. The attainment of 2000 bands. Hum. Genet. 56, 293-298 (1981).
49. R. K. Sachs, C. van den Engh, B. Trask, H. Yokota and J. E. Hearst, A random-walk/giant-loop model for interphase chromosomes. Proc. Natl. Acad. Sci. USA 92, 2710-2714 (1995).
50. H. Yokota, C. van den Engh, J. E. Hearst, R. K. Sachs and B. J. Trask, Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in the human G0/G1 interphase nucleus. J. Cell Biol. 130, 1239-1249 (1995).