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Volumn 4, Issue 4, 1998, Pages 546-551

The natural history of the immune response to exogenous factor VIII in severe haemophilia A

Author keywords

Antibody; Factor VIII; Haemophilia A; Immune response; Inhibitor

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 INHIBITOR;

EID: 0031830428     PISSN: 13518216     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2516.1998.440546.x     Document Type: Conference Paper
Times cited : (19)

References (15)
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    • Anti-factor VIII antibodies of hemophiliac patients are frequently directed towards nonfunctional determinants and do not exhibit isotypic restriction
    • Gilles JGG, Arnout J, Vermylen J, Saint-Remy J-MR. Anti-factor VIII antibodies of hemophiliac patients are frequently directed towards nonfunctional determinants and do not exhibit isotypic restriction. Blood 1993; 82: 2452-61.
    • (1993) Blood , vol.82 , pp. 2452-2461
    • Gilles, J.G.G.1    Arnout, J.2    Vermylen, J.3    Saint-Remy, J.-M.R.4
  • 7
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    • Human anti-factor VIII antibodies: Epitope localization and inhibitory function
    • Scandella D. Human anti-factor VIII antibodies: epitope localization and inhibitory function. Vox Sang 1996; 70: 9-14.
    • (1996) Vox Sang , vol.70 , pp. 9-14
    • Scandella, D.1
  • 8
    • 0029861521 scopus 로고    scopus 로고
    • Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition
    • Saenko EL, Shima M, Gilbert GE, Scandella D. Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition. J Biol Chem 1996; 271: 27424-31.
    • (1996) J Biol Chem , vol.271 , pp. 27424-27431
    • Saenko, E.L.1    Shima, M.2    Gilbert, G.E.3    Scandella, D.4
  • 12
    • 0030926974 scopus 로고    scopus 로고
    • The inhibitor antibody response is more complex in hemophilia A patients than in most nonhemophiliacs with factor VIII autoantibodies
    • Prescott R, Nakai H, Saenko EL, Scharrer I, Nilsson IM, Humphries J, Hurst D, Bray G, Scandella D. The inhibitor antibody response is more complex in hemophilia A patients than in most nonhemophiliacs with factor VIII autoantibodies. Blood 1997; 89: 3663-71.
    • (1997) Blood , vol.89 , pp. 3663-3671
    • Prescott, R.1    Nakai, H.2    Saenko, E.L.3    Scharrer, I.4    Nilsson, I.M.5    Humphries, J.6    Hurst, D.7    Bray, G.8    Scandella, D.9
  • 13
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    • A multicenter study of recombinant factor VIII (Recombinate): Safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A
    • Bray GL, Gomperts ED, Courter S, Gruppo R, Gordon EM, Manco-Johnson M, Shapiro A, Scheibel E, White III G, Lee M, et al. A multicenter study of recombinant factor VIII (Recombinate): Safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. Blood 1994; 83: 2428-35.
    • (1994) Blood , vol.83 , pp. 2428-2435
    • Bray, G.L.1    Gomperts, E.D.2    Courter, S.3    Gruppo, R.4    Gordon, E.M.5    Manco-Johnson, M.6    Shapiro, A.7    Scheibel, E.8    White III, G.9    Lee, M.10
  • 14
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    • In vivo recovery of factor VIII following transfusion: A survey of recent data and publications to assess the influence of standards used for potency assessment
    • Prowse CV. In vivo recovery of factor VIII following transfusion: a survey of recent data and publications to assess the influence of standards used for potency assessment. Thromb Haemostas 1995; 74: 1191-6.
    • (1995) Thromb Haemostas , vol.74 , pp. 1191-1196
    • Prowse, C.V.1
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    • High incidence of anti-FVIII antibodies against non-coagulant epitopes in haemophilia A patients: A possible role for the half-life of transfused FVIII
    • Dazzi F, Tison T, Vianello F, Radossi P, Zerbinati P, Carraro P, Poletti A, Girolami A. High incidence of anti-FVIII antibodies against non-coagulant epitopes in haemophilia A patients: a possible role for the half-life of transfused FVIII. Brit J Haematol 1996; 93: 688-93.
    • (1996) Brit J Haematol , vol.93 , pp. 688-693
    • Dazzi, F.1    Tison, T.2    Vianello, F.3    Radossi, P.4    Zerbinati, P.5    Carraro, P.6    Poletti, A.7    Girolami, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.